MA56056A - Nouveau procédé efficace de synthèse de 2-amino-5-chloro-n-,3-diméthylbenzamide - Google Patents

Nouveau procédé efficace de synthèse de 2-amino-5-chloro-n-,3-diméthylbenzamide

Info

Publication number
MA56056A
MA56056A MA056056A MA56056A MA56056A MA 56056 A MA56056 A MA 56056A MA 056056 A MA056056 A MA 056056A MA 56056 A MA56056 A MA 56056A MA 56056 A MA56056 A MA 56056A
Authority
MA
Morocco
Prior art keywords
dimethylbenzamide
chloro
synthesis
amino
efficient process
Prior art date
Application number
MA056056A
Other languages
English (en)
Inventor
Liang Chen
Yefeng Fan
Jianhua Mao
Zhijian Xu
Original Assignee
Fmc Agro Singapore Pte Ltd
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Agro Singapore Pte Ltd, Fmc Corp filed Critical Fmc Agro Singapore Pte Ltd
Publication of MA56056A publication Critical patent/MA56056A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/10Preparation of carboxylic acid amides from compounds not provided for in groups C07C231/02 - C07C231/08
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/14Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/08Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/12Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reactions not involving the formation of oxyimino groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32Oximes
    • C07C251/34Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/36Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atoms of the oxyimino groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/38Oxygen atoms in positions 2 and 3, e.g. isatin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/241,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26Two oxygen atoms, e.g. isatoic anhydride

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
MA056056A 2019-11-01 2020-10-28 Nouveau procédé efficace de synthèse de 2-amino-5-chloro-n-,3-diméthylbenzamide MA56056A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962929138P 2019-11-01 2019-11-01

Publications (1)

Publication Number Publication Date
MA56056A true MA56056A (fr) 2022-04-06

Family

ID=73543326

Family Applications (1)

Application Number Title Priority Date Filing Date
MA056056A MA56056A (fr) 2019-11-01 2020-10-28 Nouveau procédé efficace de synthèse de 2-amino-5-chloro-n-,3-diméthylbenzamide

Country Status (15)

Country Link
US (2) US11542241B2 (fr)
EP (2) EP3976583B1 (fr)
JP (3) JP7730309B2 (fr)
KR (1) KR20220091537A (fr)
CN (3) CN114080388A (fr)
AU (1) AU2020372895A1 (fr)
BR (1) BR112022008061A2 (fr)
HU (1) HUE067805T2 (fr)
IL (3) IL313390A (fr)
MA (1) MA56056A (fr)
MX (2) MX2022005229A (fr)
PL (1) PL3976583T3 (fr)
TW (2) TWI881549B (fr)
WO (1) WO2021086957A1 (fr)
ZA (2) ZA202204803B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112022008061A2 (pt) * 2019-11-01 2022-07-12 Fmc Corp Processo eficaz para síntese de 2-amino-5-cloro-n,3-dimetilbenzamida
WO2023073502A1 (fr) * 2021-10-28 2023-05-04 Laurus Labs Limited Procédés de préparation de composés intermédiaires de pyrazole-carboxylate et d'anthranilamide
TW202421613A (zh) * 2022-10-19 2024-06-01 美商富曼西公司 合成2-胺基-5-氯-n,3-二甲基苯甲醯胺之高效新方法
CN115594608A (zh) * 2022-10-20 2023-01-13 九江善水科技股份有限公司(Cn) 一种氯虫苯甲酰胺中间体的制备方法
CN116730859B (zh) * 2023-06-01 2025-06-13 青岛科技大学 一种2-氨基-5-氯-n,3-二甲基苯甲酰胺的制备方法
CN116987002A (zh) * 2023-06-20 2023-11-03 湖北可赛化工有限公司 一种2-氨基-5-氯-n,3-二甲基苯甲酰胺的制备方法
TW202542105A (zh) 2023-12-19 2025-11-01 印度商皮埃企業有限公司 經取代的鄰胺基苯甲醯胺化合物、其中間產物及其鹽的合成方法
WO2025134140A1 (fr) * 2023-12-19 2025-06-26 Pi Industries Ltd. Procédé de synthèse de composés amides anthraniliques substitués, intermédiaires et sels associés

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FR1421255A (fr) * 1962-09-18 1965-12-17 Parke Davis & Co Nouveaux anhydrides d'acides n-arylisatoïques et procédés pour leur préparation
DE2262830A1 (de) * 1972-12-22 1974-06-27 Bayer Ag Verfahren zur herstellung von oximinoacet-o-toluidid
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
US6472349B1 (en) 1999-03-31 2002-10-29 Basf Aktiengesellschaft Pyridine-2,3-dicarboxylic acid diamides
CA2540289A1 (fr) * 2003-10-02 2005-04-14 Cephalon, Inc. Derives d'indole substitues
JP4989976B2 (ja) * 2004-02-13 2012-08-01 プレジデント アンド フェロウズ オブ ハーバード カレッジ 翻訳開始阻害剤としての3−3−二置換オキシインドール
TWI363756B (en) * 2004-12-07 2012-05-11 Du Pont Method for preparing n-phenylpyrazole-1-carboxamides
ZA200810231B (en) * 2006-07-19 2010-07-28 Du Pont Process for making 3-substituted 2-amino-5-halobenzamides
US20110065671A1 (en) * 2008-05-19 2011-03-17 Harris Joel M Bicyclic heterocycle derivatives and use thereof as gpr119 modulators
CN101786980B (zh) * 2010-03-31 2012-12-05 滨海康杰化学有限公司 靛红衍生物的合成方法
CN102311424A (zh) * 2010-07-05 2012-01-11 温州大学 一种氯虫苯甲酰胺关键中间体的合成方法
US8440662B2 (en) * 2010-10-31 2013-05-14 Endo Pharmaceuticals, Inc. Substituted quinazoline and pyrido-pyrimidine derivatives
CN103058993B (zh) * 2013-01-08 2014-06-04 河南师范大学 一种氯虫苯甲酰胺的制备方法
EP2984088B1 (fr) 2013-04-12 2019-03-20 Asana BioSciences, LLC Quinazolines et azaquinazolines en tant que doubles inhibiteurs des voies ras/raf/mek/erk et pi3k/akt/pten/mtor
BR112018007021B1 (pt) * 2015-10-06 2024-01-09 Proteostasis Therapeutics, Inc Composto, composição compreendendo os ditos compostos e uso dos mesmos para tratar fibrose cística
CN105732462B (zh) * 2016-02-03 2019-01-04 常州工程职业技术学院 一种合成7-卤代吲哚的方法
BR112022008061A2 (pt) * 2019-11-01 2022-07-12 Fmc Corp Processo eficaz para síntese de 2-amino-5-cloro-n,3-dimetilbenzamida

Also Published As

Publication number Publication date
IL292210A (en) 2022-06-01
PL3976583T3 (pl) 2024-09-16
IL313390A (en) 2024-08-01
TW202408988A (zh) 2024-03-01
IL294707B2 (en) 2024-12-01
KR20220091537A (ko) 2022-06-30
CN114621130A (zh) 2022-06-14
JP2023501851A (ja) 2023-01-20
MX2026001742A (es) 2026-03-02
IL292210B1 (en) 2023-03-01
CN115536540B (zh) 2025-03-25
BR112022008061A2 (pt) 2022-07-12
EP3976583A1 (fr) 2022-04-06
TW202126616A (zh) 2021-07-16
IL294707A (en) 2022-09-01
US20220242837A1 (en) 2022-08-04
ZA202403308B (en) 2025-08-27
IL292210B2 (en) 2023-07-01
HUE067805T2 (hu) 2024-11-28
AU2020372895A1 (en) 2022-05-26
CN114080388A (zh) 2022-02-22
TWI881549B (zh) 2025-04-21
ZA202204803B (en) 2024-08-28
CN114621130B (zh) 2025-02-25
US11542241B2 (en) 2023-01-03
JP7730309B2 (ja) 2025-08-27
EP3976583B1 (fr) 2024-05-01
WO2021086957A1 (fr) 2021-05-06
JP2025061138A (ja) 2025-04-10
JP2023002456A (ja) 2023-01-10
CN115536540A (zh) 2022-12-30
US20230096826A1 (en) 2023-03-30
EP4119542A1 (fr) 2023-01-18
US12304893B2 (en) 2025-05-20
MX2022005229A (es) 2022-06-08
IL294707B1 (en) 2024-08-01

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