BR9203266A - Composto,formulacao farmaceutica,processo para inibir 5alfa-reductase,processos para tratar hiperplasia benigna da prostata,seborreia e alopecia androgenica - Google Patents

Composto,formulacao farmaceutica,processo para inibir 5alfa-reductase,processos para tratar hiperplasia benigna da prostata,seborreia e alopecia androgenica

Info

Publication number: BR9203266A
Authority: BR; Brazil
Prior art keywords: reductase; 5alfa; seborrhea; inhibit; processes
Prior art date: 1991-08-21

Application number

BR929203266A

Other languages

English (en)

Portuguese (pt)

Inventor

Kennety Steven Hirsch

Charles David Jones

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-08-21

Filing date

1992-08-21

Publication date

1993-04-06

1992-08-21 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1993-04-06 Publication of BR9203266A publication Critical patent/BR9203266A/pt

Links

150000001875 compounds Chemical class 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
238000000034 method Methods 0.000 title 2
201000004384 Alopecia Diseases 0.000 title 1
206010004446 Benign prostatic hyperplasia Diseases 0.000 title 1
206010039792 Seborrhoea Diseases 0.000 title 1
201000002996 androgenic alopecia Diseases 0.000 title 1
208000008742 seborrheic dermatitis Diseases 0.000 title 1
HHBUAEFLOSPGQP-UHFFFAOYSA-N 2,4,5,6-tetrahydro-1h-benzo[f]quinolin-3-one Chemical class C1=CC=C2C(CCC(N3)=O)=C3CCC2=C1 HHBUAEFLOSPGQP-UHFFFAOYSA-N 0.000 abstract 1
239000002677 5-alpha reductase inhibitor Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
- C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Photoreceptors In Electrophotography (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Fats And Perfumes (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

BR929203266A 1991-08-21 1992-08-21 Composto,formulacao farmaceutica,processo para inibir 5alfa-reductase,processos para tratar hiperplasia benigna da prostata,seborreia e alopecia androgenica BR9203266A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US74813491A	1991-08-21	1991-08-21
US07/780,166 US5250539A (en)	1991-08-21	1991-10-21	Hexahydrobenzo[f]quinolinones

Publications (1)

Publication Number	Publication Date
BR9203266A true BR9203266A (pt)	1993-04-06

Family

ID=27114886

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR929203266A BR9203266A (pt)	1991-08-21	1992-08-21	Composto,formulacao farmaceutica,processo para inibir 5alfa-reductase,processos para tratar hiperplasia benigna da prostata,seborreia e alopecia androgenica

Country Status (17)

Country	Link
US (1)	US5250539A (2)
EP (1)	EP0531026B1 (2)
JP (1)	JPH05213889A (2)
KR (1)	KR930004269A (2)
CN (1)	CN1069488A (2)
AT (1)	ATE173467T1 (2)
AU (1)	AU2118292A (2)
BR (1)	BR9203266A (2)
CA (1)	CA2076509A1 (2)
CZ (1)	CZ256792A3 (2)
DE (1)	DE69227612T2 (2)
FI (1)	FI923751L (2)
HU (1)	HUT68064A (2)
IL (1)	IL102880A0 (2)
MX (1)	MX9204815A (2)
NO (1)	NO923266L (2)
TW (1)	TW218011B (2)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU654573B2 (en) *	1991-08-21	1994-11-10	Eli Lilly And Company	Benzo(f)quinolinones
US5239075A (en) *	1991-08-21	1993-08-24	Eli Lilly And Company	Process for the preparation of benzo (f) quinolinones
GB9317314D0 (en) *	1993-08-20	1993-10-06	Smithkline Beecham Corp	Compounds
US5578724A (en) *	1994-09-20	1996-11-26	Eli Lilly And Company	Process for preparation of benzo[f]quinolinones
FR2737721B1 (fr)	1995-08-08	1997-09-05	Roussel Uclaf	Nouveaux composes biphenyles, leur procede de preparation et les intermediaires de ce procede, leur application a titre de medicament et les compositions pharmaceutiques les contenant
EP0926148A1 (en)	1997-12-23	1999-06-30	Applied Research Systems Ars Holding N.V.	Benzo (C)quinolizine derivatives, their preparation and use as 5-alphareductases inhibitors
GB0222516D0 (en) *	2002-09-27	2002-11-06	Karobio Ab	Novel compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0102046A1 (en) *	1982-08-26	1984-03-07	Schering Corporation	Tricyclic lactams, method for making them, pharmaceutical compositions containing them
US4511569A (en) *	1982-08-26	1985-04-16	Schering Corporation	Tricyclic lactams and derivatives useful in increasing cardiac contractility
US4859681A (en) *	1984-02-27	1989-08-22	Merck & Co., Inc.	17 α-Acyl-4-aza-5a-androst-1-en-3-ones as 5 alpha-reductase inhibitors
US5120742A (en) *	1984-02-27	1992-06-09	Merck & Co., Inc.	17 β-acyl-4-aza-5 α-androst-1-ene-3-ones as 5 α-reductase inhibitors
FI82931C (fi) *	1986-01-23	1991-05-10	Hoffmann La Roche	Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensazecinderivat.
US4888336A (en) *	1987-01-28	1989-12-19	Smithkline Beckman Corporation	Steroid 5-alpha-reductase inhibitors
DE3872937T2 (de) *	1987-05-11	1993-01-21	Ono Pharmaceutical Co	Benzoylaminophenoxybuttersaeure-derivate.
IN167395B (2) *	1987-07-21	1990-10-20	Hoffmann La Roche
US5120840A (en) *	1990-08-01	1992-06-09	Merrell Dow Pharmaceuticals Inc.	4-amino-4-ene-steroids and their use as 5α-reductase inhibitors

1991
- 1991-10-21 US US07/780,166 patent/US5250539A/en not_active Expired - Fee Related
1992
- 1992-08-19 HU HU9202710A patent/HUT68064A/hu unknown
- 1992-08-20 JP JP4221358A patent/JPH05213889A/ja active Pending
- 1992-08-20 NO NO92923266A patent/NO923266L/no unknown
- 1992-08-20 AU AU21182/92A patent/AU2118292A/en not_active Abandoned
- 1992-08-20 IL IL102880A patent/IL102880A0/xx unknown
- 1992-08-20 CA CA002076509A patent/CA2076509A1/en not_active Abandoned
- 1992-08-20 KR KR1019920014993A patent/KR930004269A/ko not_active Withdrawn
- 1992-08-20 AT AT92307636T patent/ATE173467T1/de not_active IP Right Cessation
- 1992-08-20 CZ CS922567A patent/CZ256792A3/cs unknown
- 1992-08-20 DE DE69227612T patent/DE69227612T2/de not_active Expired - Fee Related
- 1992-08-20 EP EP92307636A patent/EP0531026B1/en not_active Expired - Lifetime
- 1992-08-20 CN CN92109570A patent/CN1069488A/zh active Pending
- 1992-08-20 MX MX9204815A patent/MX9204815A/es unknown
- 1992-08-20 FI FI923751A patent/FI923751L/fi not_active Application Discontinuation
- 1992-08-21 BR BR929203266A patent/BR9203266A/pt not_active Application Discontinuation
- 1992-09-25 TW TW081107628A patent/TW218011B/zh active

Also Published As

Publication number	Publication date
MX9204815A (es)	1993-12-01
EP0531026A1 (en)	1993-03-10
NO923266D0 (no)	1992-08-20
FI923751A0 (fi)	1992-08-20
IL102880A0 (en)	1993-01-31
DE69227612D1 (de)	1998-12-24
AU2118292A (en)	1993-02-25
CN1069488A (zh)	1993-03-03
EP0531026B1 (en)	1998-11-18
TW218011B (2)	1993-12-21
JPH05213889A (ja)	1993-08-24
FI923751A7 (fi)	1993-02-22
HUT68064A (en)	1995-05-29
CA2076509A1 (en)	1993-02-22
CZ256792A3 (en)	1993-04-14
FI923751L (fi)	1993-02-22
DE69227612T2 (de)	1999-05-06
KR930004269A (ko)	1993-03-22
NO923266L (no)	1993-02-22
ATE173467T1 (de)	1998-12-15
US5250539A (en)	1993-10-05

Legal Events

Date	Code	Title	Description
1995-10-03	FA1	Application withdrawn (art. 18(2))

Publication	Publication Date	Title
PT981341E (pt)	2003-10-31	Uso de derivados de acido betulinico para o tratamento e prevencao de melanona
NZ234414A (en)	1999-05-28	A method of prophylaxis and/or treatment of benign prostatic hyperplasia (bph)
PT1203770E (pt)	2005-05-31	Piran -2-onas e 5, 6-di-hidropiran-2-onas uteis para o tratamento de hiperplasia e outras doencas
BR1100217A (pt)	1999-11-09	Composto, e, composição farmacêutica
PL337758A1 (en)	2000-09-11	Derivatives of piperazine and their application as anti-inflammatory agents
AU5377698A (en)	1998-07-03	Substituted pyrrolyl compounds for the treatment of inflammation
HRP930239A2 (en)	1996-06-30	Anti-inflamatory 4-aminophenol derivatives
MX9702382A (es)	1998-02-28	Nuevos derivados de pirimidona con actividad antifungica.
FI931765A7 (fi)	1993-10-21	Steroidijohdannaisia eturauhasen liikakasvun käsittelyyn, niiden valmistus ja käytöt
ATE212351T1 (de)	2002-02-15	Androsten-derivate
WO1997004788A3 (en)	1997-03-27	Use of calendula glycosides for the treatment of psoriasis
ZA957507B (en)	1996-04-18	L-carnitine salt and cosmetic and pharmaceutical compositions containing same for treating dermatoses
ATE178795T1 (de)	1999-04-15	7-substituierte-4-aza-steroid-derivate als 5- alpha-reductase-hemmer
DE69519728D1 (de)	2001-02-01	17 beta-aryl-4-aza-steroidderivate
ZA957506B (en)	1996-04-18	L-carnite salt and cosmetic and pharmaceutical compositions containing same for treating dermatoses
DK0742214T3 (da)	1999-12-13	I hjerte-kar-systemet aktive, nye seco-D steroider samt farmaceutiske præparater indeholdende sådanne
ATE173467T1 (de)	1998-12-15	Hexahydrobenzo(f)quinolinone als 5-alpha- reduktase inhibitoren