DK0742214T3 - I hjerte-kar-systemet aktive, nye seco-D steroider samt farmaceutiske præparater indeholdende sådanne - Google Patents
I hjerte-kar-systemet aktive, nye seco-D steroider samt farmaceutiske præparater indeholdende sådanneInfo
- Publication number
- DK0742214T3 DK0742214T3 DK96830206T DK96830206T DK0742214T3 DK 0742214 T3 DK0742214 T3 DK 0742214T3 DK 96830206 T DK96830206 T DK 96830206T DK 96830206 T DK96830206 T DK 96830206T DK 0742214 T3 DK0742214 T3 DK 0742214T3
- Authority
- DK
- Denmark
- Prior art keywords
- new
- seco
- steroids
- well
- pharmaceutical preparations
- Prior art date
Links
- 150000003431 steroids Chemical class 0.000 title abstract 2
- 210000000748 cardiovascular system Anatomy 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 229940125692 cardiovascular agent Drugs 0.000 abstract 1
- 239000002327 cardiovascular agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- IMCGHZIGRANKHV-AJNGGQMLSA-N tert-butyl (3s,5s)-2-oxo-5-[(2s,4s)-5-oxo-4-propan-2-yloxolan-2-yl]-3-propan-2-ylpyrrolidine-1-carboxylate Chemical compound O1C(=O)[C@H](C(C)C)C[C@H]1[C@H]1N(C(=O)OC(C)(C)C)C(=O)[C@H](C(C)C)C1 IMCGHZIGRANKHV-AJNGGQMLSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95RM000303A IT1282286B1 (it) | 1995-05-11 | 1995-05-11 | Seco-d steroidi sul sistema cardiovascolare, processi per la loro preparazione e composizioni farmaceutiche che li contengono. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0742214T3 true DK0742214T3 (da) | 1999-12-13 |
Family
ID=11403363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96830206T DK0742214T3 (da) | 1995-05-11 | 1996-04-11 | I hjerte-kar-systemet aktive, nye seco-D steroider samt farmaceutiske præparater indeholdende sådanne |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5731345A (da) |
| EP (1) | EP0742214B1 (da) |
| JP (1) | JPH09291086A (da) |
| AT (1) | ATE181324T1 (da) |
| CA (1) | CA2174715A1 (da) |
| DE (1) | DE69602886T2 (da) |
| DK (1) | DK0742214T3 (da) |
| ES (1) | ES2133918T3 (da) |
| GR (1) | GR3031118T3 (da) |
| IT (1) | IT1282286B1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19633376A1 (de) * | 1996-08-19 | 1998-02-26 | Sigma Tau Ind Farmaceuti | Neue Seco-D-Steroide, die auf das kardiovaskuläre System wirken, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten |
| ATE473759T1 (de) | 1998-05-22 | 2010-07-15 | Univ Leland Stanford Junior | Bifunktionelle moleküle sowie darauf basierende therapien. |
| AU2002322720B2 (en) | 2001-07-25 | 2008-11-13 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| US20040064050A1 (en) * | 2002-09-20 | 2004-04-01 | Jun Liu | System and method for screening tissue |
| CN102379684B (zh) | 2005-04-28 | 2014-11-19 | 普罗透斯数字保健公司 | 药物信息系统 |
| US9062126B2 (en) | 2005-09-16 | 2015-06-23 | Raptor Pharmaceuticals Inc. | Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof |
| ES2380491T3 (es) * | 2005-11-25 | 2012-05-14 | Rostaquo S.P.A. | Formas cristalinas adicionales de la Rostafuroxina |
| EP2398500B1 (en) | 2009-02-20 | 2019-03-13 | 2-BBB Medicines B.V. | Glutathione-based drug delivery system |
| ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4221636C1 (de) * | 1992-07-01 | 1994-03-31 | Sigma Tau Ind Farmaceuti | Cyclopentanperhydrophenanthren-17beta-(3-furyl)-3-Derivate |
| DE4221538C1 (de) * | 1992-07-01 | 1994-03-31 | Sigma Tau Ind Farmaceuti | 14-Desoxy-14alpha-cardenolid-3beta-thioderivate |
| DE4227605C2 (de) * | 1992-08-20 | 1995-02-16 | Sigma Tau Ind Farmaceuti | 17-Hydroxyiminomethyl-14beta-hydroxy-5ß-androstan-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die dieselben enthalten |
-
1995
- 1995-05-11 IT IT95RM000303A patent/IT1282286B1/it active IP Right Grant
-
1996
- 1996-04-11 ES ES96830206T patent/ES2133918T3/es not_active Expired - Lifetime
- 1996-04-11 DK DK96830206T patent/DK0742214T3/da active
- 1996-04-11 AT AT96830206T patent/ATE181324T1/de not_active IP Right Cessation
- 1996-04-11 DE DE69602886T patent/DE69602886T2/de not_active Expired - Fee Related
- 1996-04-11 EP EP96830206A patent/EP0742214B1/en not_active Expired - Lifetime
- 1996-04-15 US US08/632,124 patent/US5731345A/en not_active Expired - Fee Related
- 1996-04-22 CA CA002174715A patent/CA2174715A1/en not_active Abandoned
- 1996-04-26 JP JP8106864A patent/JPH09291086A/ja active Pending
-
1999
- 1999-08-31 GR GR990402200T patent/GR3031118T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ITRM950303A0 (it) | 1995-05-11 |
| IT1282286B1 (it) | 1998-03-16 |
| GR3031118T3 (en) | 1999-12-31 |
| CA2174715A1 (en) | 1996-11-12 |
| ITRM950303A1 (it) | 1996-11-11 |
| EP0742214B1 (en) | 1999-06-16 |
| DE69602886T2 (de) | 1999-11-04 |
| ES2133918T3 (es) | 1999-09-16 |
| JPH09291086A (ja) | 1997-11-11 |
| DE69602886D1 (de) | 1999-07-22 |
| EP0742214A1 (en) | 1996-11-13 |
| ATE181324T1 (de) | 1999-07-15 |
| US5731345A (en) | 1998-03-24 |
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