BR9206736A - Composição para afetar o crescimento de tecido vivo em mamíferos processos para promover a angiogenese em mamíferos para tratar tecido transplantado ou órgãos em mamíferos e para tratar osso danificado ou transplantado - Google Patents

Composição para afetar o crescimento de tecido vivo em mamíferos processos para promover a angiogenese em mamíferos para tratar tecido transplantado ou órgãos em mamíferos e para tratar osso danificado ou transplantado

Info

Publication number: BR9206736A
Authority: BR; Brazil
Prior art keywords: mammals; treat; transplanted; tissue; organs
Prior art date: 1991-11-11

Application number

BR9206736A

Other languages

English (en)

Inventor

Howard C Herrmann

Eliot Barnathan

Paul B Weisz

Original Assignee

Univ Pennsylvania

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-11-11

Filing date

1992-11-10

Publication date

1995-10-31

1991-11-11 Priority claimed from IL10002391A external-priority patent/IL100023A/en

1992-11-10 Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania

1995-10-31 Publication of BR9206736A publication Critical patent/BR9206736A/pt

Links

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- C07K14/503—Fibroblast growth factor [FGF] basic FGF [bFGF]
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
- A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Dermatology (AREA)
Transplantation (AREA)
Oral & Maxillofacial Surgery (AREA)
Materials Engineering (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Orthopedic Medicine & Surgery (AREA)
Biotechnology (AREA)
Nanotechnology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Hematology (AREA)
Toxicology (AREA)
Immunology (AREA)
Surgery (AREA)
Virology (AREA)
Developmental Biology & Embryology (AREA)
Urology & Nephrology (AREA)
Botany (AREA)
Cell Biology (AREA)
Rheumatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)

BR9206736A 1991-11-11 1992-11-10 Composição para afetar o crescimento de tecido vivo em mamíferos processos para promover a angiogenese em mamíferos para tratar tecido transplantado ou órgãos em mamíferos e para tratar osso danificado ou transplantado BR9206736A (pt)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
IL10002391A IL100023A (en)	1991-11-11	1991-11-11	Pharmaceutical composition comprising a cyclodextrin derivative for the inhibition of undesired smooth muscle cell growth following angioplasty
US79032091A	1991-11-12	1991-11-12
US90059292A	1992-06-18	1992-06-18
PCT/US1992/009754 WO1993009790A1 (en)	1991-11-11	1992-11-10	Methods of inhibiting restenosis

Publications (1)

Publication Number	Publication Date
BR9206736A true BR9206736A (pt)	1995-10-31

Family

ID=27271521

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9206736A BR9206736A (pt)	1991-11-11	1992-11-10	Composição para afetar o crescimento de tecido vivo em mamíferos processos para promover a angiogenese em mamíferos para tratar tecido transplantado ou órgãos em mamíferos e para tratar osso danificado ou transplantado

Country Status (8)

Country	Link
EP (1)	EP0612249A4 (pt)
JP (1)	JPH07500843A (pt)
AU (1)	AU678760B2 (pt)
BR (1)	BR9206736A (pt)
CA (1)	CA2124857A1 (pt)
FI (1)	FI942166A7 (pt)
NO (1)	NO941738L (pt)
WO (1)	WO1993009790A1 (pt)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6515009B1 (en)	1991-09-27	2003-02-04	Neorx Corporation	Therapeutic inhibitor of vascular smooth muscle cells
DE69322721T2 (de) *	1992-09-24	1999-06-10	Terumo K.K., Tokio/Tokyo	Sulfonierte Verbindungen aus Beta-Cyclodextrinpolymer und diese enthaltendes Medikament welches die Hyperplasie von Gefässwanden hemmt
US6395494B1 (en)	1993-05-13	2002-05-28	Neorx Corporation	Method to determine TGF-β
CA2162586C (en) *	1993-05-13	2006-01-03	David J. Grainger	Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells
US5464815A (en) *	1993-09-08	1995-11-07	Genentech, Inc.	Inhibition of heparin-binding
US5464827A (en) *	1994-06-20	1995-11-07	American Home Products Corporation	Esterified polyanionic cyclodextrins as smooth muscle cell proliferation inhibitors
US5498775A (en) *	1994-11-07	1996-03-12	American Home Products Corporation	Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation
US5565432A (en) *	1994-11-07	1996-10-15	American Home Products Corporation	Smooth muscle cell proliferation inhibitors
US5773420A (en) *	1994-11-07	1998-06-30	American Home Products Corporation	Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation
US7611533B2 (en)	1995-06-07	2009-11-03	Cook Incorporated	Coated implantable medical device
DE69733664T3 (de) *	1996-04-19	2011-04-14	Grifols Inc. (n.d. Ges.d.Staates Delaware), Los Angeles	Verfahren zur INaktivierung von Viren und Lyophilisierung von Blutproteinen
AUPO888497A0 (en) *	1997-09-01	1997-09-25	Australian National University, The	Use of sulfated oligosaccharides as inhibitors of cardiovascular disease
IL125336A0 (en) *	1998-07-14	1999-03-12	Yissum Res Dev Co	Compositions for inhibition and treatment of restinosis
US6664243B1 (en)	1998-11-24	2003-12-16	Wyeth	Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6362170B1 (en)	1998-11-24	2002-03-26	American Home Products Corporation	Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6187755B1 (en)	1998-11-24	2001-02-13	American Home Products Corporation	Benzylmaltosides as inhibitors of smooth muscle cell proliferation
US7081448B2 (en)	1998-11-24	2006-07-25	Wyeth	Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6340670B1 (en)	1998-11-24	2002-01-22	American Home Products Corporation	Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6291434B1 (en)	1998-11-24	2001-09-18	American Home Products Corp.	Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6339064B1 (en)	1998-11-24	2002-01-15	American Home Products Corporation	Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en)	1998-11-24	2006-11-07	Wyeth	Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6451767B1 (en)	1998-11-24	2002-09-17	Wyeth	Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6258784B1 (en)	1998-11-24	2001-07-10	American Home Products Corp.	Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
FR2811572B1 (fr) *	2000-07-17	2003-04-18	Adir	Utilisation de cyclodextrines polysulfatees pour le traitement de l'arthrose
US6613083B2 (en)	2001-05-02	2003-09-02	Eckhard Alt	Stent device and method
FR2827799A1 (fr) *	2001-07-27	2003-01-31	Sofradim Production	Endoprothese vasculaire recouverte d'un derive fonctionnalise de dextrane et son procede de preparation
US10517883B2 (en)	2003-06-27	2019-12-31	Zuli Holdings Ltd.	Method of treating acute myocardial infarction
FR2923391B1 (fr) *	2007-11-08	2012-07-27	Biocydex	Compositions pour conserver des cellules, des tissus ou des organes, procede d'obtention et utilisations.
KR20110067130A (ko)	2008-09-22	2011-06-21	아카리오스 비.브이.	약제로서 유용한 카르복시에틸화 사이클로덱스트린 폴리설페이트
US9993427B2 (en)	2013-03-14	2018-06-12	Biorest Ltd.	Liposome formulation and manufacture

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4020160A (en) *	1975-08-15	1977-04-26	American Cyanamid Company	Cyclodextrin sulfate salts as complement inhibitors
DE3782652D1 (de) *	1986-04-04	1992-12-17	Angiogenics Ltd	Zubereitung zum stoppen von angiogenese und einem kapillar-, zellen- oder membranleck.
US5019562A (en) *	1988-01-19	1991-05-28	The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation	Growth inhibiting agent and the use thereof
CA1333363C (en) *	1988-01-19	1994-12-06	Judah Folkman	Angiogenesis inhibitor comprising fumagillin
AU614137B2 (en) *	1988-06-06	1991-08-22	Takeda Chemical Industries Ltd.	Stabilized fgf composition and production thereof
US4990610A (en) *	1988-08-25	1991-02-05	Applied Analytical Industries, Inc.	Method for preparing high potency sucralfate
US5482929A (en) *	1991-12-26	1996-01-09	Kaken Pharmaceutical Co., Ltd.	Composition of stabilized fibroblast growth factor

1992
- 1992-11-10 AU AU30742/92A patent/AU678760B2/en not_active Ceased
- 1992-11-10 FI FI942166A patent/FI942166A7/fi unknown
- 1992-11-10 BR BR9206736A patent/BR9206736A/pt not_active Application Discontinuation
- 1992-11-10 JP JP5509395A patent/JPH07500843A/ja active Pending
- 1992-11-10 WO PCT/US1992/009754 patent/WO1993009790A1/en not_active Ceased
- 1992-11-10 EP EP92924424A patent/EP0612249A4/en not_active Withdrawn
- 1992-11-10 CA CA002124857A patent/CA2124857A1/en not_active Abandoned
1994
- 1994-05-10 NO NO941738A patent/NO941738L/no unknown

Also Published As

Publication number	Publication date
WO1993009790A1 (en)	1993-05-27
NO941738L (no)	1994-07-11
FI942166L (fi)	1994-07-08
EP0612249A4 (en)	1995-11-08
AU3074292A (en)	1993-06-15
JPH07500843A (ja)	1995-01-26
CA2124857A1 (en)	1993-05-27
FI942166A0 (fi)	1994-05-10
EP0612249A1 (en)	1994-08-31
AU678760B2 (en)	1997-06-12
FI942166A7 (fi)	1994-07-08
NO941738D0 (no)	1994-05-10

Legal Events

Date	Code	Title	Description
1996-01-02	EE	Request for examination
1999-03-02	EG	Technical examination (opinion): publication of technical examination (opinion)
1999-08-24	FC	Decision: refusal
2000-03-08	FC	Decision: refusal
2018-03-27	B15K	Others concerning applications: alteration of classification	Ipc: B82Y 5/00 (2011.01), A61K 31/335 (2006.0

Publication	Publication Date	Title
BR9206736A (pt)	1995-10-31	Composição para afetar o crescimento de tecido vivo em mamíferos processos para promover a angiogenese em mamíferos para tratar tecido transplantado ou órgãos em mamíferos e para tratar osso danificado ou transplantado
EP0432560A3 (en)	1991-08-14	Set of instruments to close hollow organs and wounds
EP0653192A3 (de)	1995-11-08	Hochfrequenz-Chirurgiegerät zum Schneiden und/oder Koagulieren biologischer Gewebe.
BR8900357A (pt)	1989-09-19	Composicao e processo de tratamento de tecido e processo para a preparacao da dita composicao
SE9804183D0 (sv)	1998-12-03	Biocompatible glue
BR9701028A (pt)	1998-11-03	Instrumentos cirúrgicos e procedimentos para estabilizar o coração batendo durante cirurgia de enxerto e desvio da artéria coronária
ATE145564T1 (de)	1996-12-15	Anordnung zur bestrahlung von laserstrahlen
FI932354A0 (fi)	1993-05-24	Medicinskt foerfarande foer maetning av blodcirkulationen i ett organ ochmedel haerfoer
ES2130216T3 (es)	1999-07-01	Procedimiento de tratamiento de tejidos oseos y biomateriales implantables correspondientes.
DE59306276D1 (de)	1997-05-28	Verfahren und anordnung zur therapie von gewebe mit ultraschall
BR9306072A (pt)	1997-11-18	Processo de tratamento de tecido biologico curtido com aldeido para minimizar a calcificação in vivo
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DE69022249D1 (de)	1995-10-12	Knochenwachsapplikator zur Behandlung von Knochengewebe.
BR9102126A (pt)	1991-12-24	Composicao de tratamento de tecido
KR920700634A (ko)	1992-08-10	좌창 또는 건선 피부병을 치료하는 방법 및 여기에 사용되는 조성물
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BR8707572A (pt)	1989-03-14	Composicao para tratamento de pele resistente a umidade
BR9007769A (pt)	1992-08-11	Preparacao para o tratamento de tecido alheio,processo para a preparacao de tecido alheio ex-vivo antes de transplante ou de seu uso como material curativo,processo para o tratamento de um paciente,e,processo para realizacao de transplantes de orgaos alogenicos ou xenogenicos a um paciente humano,ou para fornecimento de curativo alogenico ou xenogenico a este paciente
BR9106377A (pt)	1993-04-27	Composicao e processo para o tratamento topico de tecido lesado ou enfermo
BR9405858A (pt)	1995-12-12	Processos de afetar o crescimento de tecido vivo em mamiferos compostos e composiçÕes para os mesmos
DE69737029D1 (de)	2007-01-11	Biomembran zur substitution, rekonstruktion, induktion der angiogenese, neubildung oder regeneration von menschlichen oder tierischen organen oder gewebe
IT1241681B (it)	1994-01-31	Impianto ortopedico in particolare per l'impiego per la riparazione e/o ricostruzione chirurgica di giunzioni del corpo umano
ATE79265T1 (de)	1992-08-15	Mittel zur behandlung mykotischer, mikrobischer und anderer gewebsschaedigender und pathologischer manifestationen und gewebsdeformationen.
ATE382378T1 (de)	2008-01-15	Implantatmaterial