BR9503876A - Quinoxalina-2,3-diona-oxa-ou tec-alifaticamente ligada em ponte processo para sua preparação compostos uso dos mesmos e composições farmacêuticas - Google Patents

Quinoxalina-2,3-diona-oxa-ou tec-alifaticamente ligada em ponte processo para sua preparação compostos uso dos mesmos e composições farmacêuticas

Info

Publication number
BR9503876A
BR9503876A BR9503876A BR9503876A BR9503876A BR 9503876 A BR9503876 A BR 9503876A BR 9503876 A BR9503876 A BR 9503876A BR 9503876 A BR9503876 A BR 9503876A BR 9503876 A BR9503876 A BR 9503876A
Authority
BR
Brazil
Prior art keywords
techno
quinoxaline
oxa
dione
pharmaceutical compositions
Prior art date
Application number
BR9503876A
Other languages
English (en)
Inventor
Robert Moretti
Kaspar Zimmermann
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of BR9503876A publication Critical patent/BR9503876A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BR9503876A 1994-09-01 1995-08-31 Quinoxalina-2,3-diona-oxa-ou tec-alifaticamente ligada em ponte processo para sua preparação compostos uso dos mesmos e composições farmacêuticas BR9503876A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH268094 1994-09-01
CH40295 1995-02-09

Publications (1)

Publication Number Publication Date
BR9503876A true BR9503876A (pt) 1996-09-17

Family

ID=25684470

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9503876A BR9503876A (pt) 1994-09-01 1995-08-31 Quinoxalina-2,3-diona-oxa-ou tec-alifaticamente ligada em ponte processo para sua preparação compostos uso dos mesmos e composições farmacêuticas

Country Status (12)

Country Link
EP (1) EP0705835A1 (pt)
JP (1) JPH08109185A (pt)
KR (1) KR960010651A (pt)
CN (1) CN1133844A (pt)
AU (1) AU3028795A (pt)
BR (1) BR9503876A (pt)
CA (1) CA2157231A1 (pt)
FI (1) FI954072A7 (pt)
HU (1) HUT73436A (pt)
IL (1) IL115103A0 (pt)
NO (1) NO953420L (pt)
NZ (1) NZ272888A (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA9711274B (en) * 1996-12-16 1998-06-23 Warner Lambert Co Tricyclic quinoxaline derivatives as neuroprotective agents.
US6288075B1 (en) 1998-02-26 2001-09-11 Rhone-Poulenc Rorer S.A. Thiazolo[5,4,3-ij]quinolines, preparation and medicines containing the same
FR2760237B1 (fr) * 1997-02-28 1999-04-16 Rhone Poulenc Rorer Sa Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
FR2766487B1 (fr) * 1997-07-28 1999-08-27 Rhone Poulenc Rorer Sa Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
US8354427B2 (en) 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
CN101891680B (zh) 2004-06-24 2014-10-29 沃泰克斯药物股份有限公司 Atp-结合弹夹转运蛋白的调控剂
DK3219705T3 (da) 2005-12-28 2020-04-14 Vertex Pharma Farmaceutiske sammensætninger af den amorfe form af n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinolin-3-carboxamid
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
US12458635B2 (en) 2008-08-13 2025-11-04 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
KR101727762B1 (ko) 2009-03-20 2017-04-17 버텍스 파마슈티칼스 인코포레이티드 낭성 섬유증 막횡단 전도도 조절자의 조정자의 제조 방법
US8802700B2 (en) 2010-12-10 2014-08-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
JP2015511583A (ja) 2012-02-27 2015-04-20 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ 薬学的組成物およびその投与
CN107250113B (zh) 2014-10-07 2019-03-29 弗特克斯药品有限公司 囊性纤维化跨膜传导调节蛋白的调节剂的共晶

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK715888D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
ES2067744T3 (es) * 1989-06-09 1995-04-01 Upjohn Co Aminas heterociclicas con actividad sobre el sistema nervioso central.
JPH05117276A (ja) * 1991-10-23 1993-05-14 Sumitomo Pharmaceut Co Ltd 新規な３環性キノキサリンジオン誘導体
WO1994000124A1 (en) * 1992-06-22 1994-01-06 Eckard Weber Glycine receptor antagonists and the use thereof
ATE157977T1 (de) * 1992-10-13 1997-09-15 Warner Lambert Co Chinoxalinderivate als eaa antagonisten
US5631373A (en) * 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones

Also Published As

Publication number Publication date
CN1133844A (zh) 1996-10-23
EP0705835A1 (de) 1996-04-10
HU9502562D0 (en) 1995-10-30
JPH08109185A (ja) 1996-04-30
AU3028795A (en) 1996-03-14
NZ272888A (en) 1997-05-26
FI954072A0 (fi) 1995-08-30
NO953420L (no) 1996-03-04
IL115103A0 (en) 1995-12-08
CA2157231A1 (en) 1996-03-02
KR960010651A (ko) 1996-04-20
NO953420D0 (no) 1995-08-31
FI954072A7 (fi) 1996-03-02
HUT73436A (en) 1996-07-29

Similar Documents

Publication Publication Date Title
BR9707251A (pt) Compostos processo para a preparação dos mesmos e composições farmacêuticas
BR9504509A (pt) Composto processo para sua preparaçao e formulaçao farmaceûtica
BR0017030B1 (pt) derivados de tiazolilamida, processo para sua preparação, composição farmacêutica que os compreende e uso dos mesmos
BR9501770A (pt) Uso de um composto,composto,formulação farmacêutica e processo para preparar um composto
BR9506561A (pt) Co-grânulo homogêneo composição detergente tablete de detergente processos para sua preparação e uso dos mesmos
BR9910900B1 (pt) compostos derivados de isotiazol, processo para sua preparação e composição farmacêutica dos mesmos
BR9611986A (pt) Compostos processo para a preparação dos mesmos composição farmcéutica e utilização dos compostos
BR9202653A (pt) Derivados de 3-aril-4-hidroxi-delta3-dihidrofuran ona e derivados de 3-aril-4-hidroxi-delta-dihidrotiofenona,processo para sua preparacao,composicoes inseticidas,processo para o combate de insetos,emprego e processo para a preparacao de composicoes
BR9000631A (pt) Compostos contendo grupos nitro,processo para sua preparacao,composicoes inseticidas,processo para sua preparacao e processo para o combate de insetos nocivos
BR9004852A (pt) Composto,processo para sua preparacao,sua aplicacao e composicao farmaceutica
BR9506106A (pt) Composto processo para sua preparação medicamento e composição farmacêutica
BR1100524A (pt) Compostos, processo para sua preparação; compostos intermediários para os mesmos, e composições farmacêuticas
FI953384L (fi) Uusi bentsolitiaditsiiniyhdiste, menetelmä sen valmistamiseksi ja sitä sisältävät farmaseuttiset koostumukset
BR9600339A (pt) Compostos composições farmacêuticas processo para a preparação de um composto e uso dos mesmos
BR9602025A (pt) Composto composição farmacêutica uso e processo para a preparação de um composto
EE03996B1 (et) Farmatseutilised kompositsioonid, nende valmistamismeetod ja kasutamine
FI953956A7 (fi) 2,3-rengaskondensoidut 1,4-dihydropyridiinit, menetelmät niiden valmistamiseksi ja niiden käyttö lääkkeinä
PT939083E (pt) Complexos de ferro-succinilcaseina procedimento para sua preparacao e suas composicoes farmaceuticas
FI953532A7 (fi) Nitroglyserolia sisältävä laastari, menetelmä sen valmistamiseksi ja s en käyttö
FI951091A7 (fi) Uudet alkyyliaminoindaaniyhdisteet, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
BR9506062A (pt) Compostos processo para sua preparação medicamento e composição farmacêutica
BR9302359A (pt) Composto,processo para sua preparacao,medicamento e uso
BR9710215A (pt) Composto processo para sua preparação e formulação farmacéutica
BR9703403B1 (pt) compostos, processo para preparação de compostos, utilização de composto e processo para preparação de composição farmacêutica.
BR9508518A (pt) 8-Flúor-antraciclinas processo para sua preparação e compsição farmacéutica contendo as mesma

Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law