BR9608894A - Produtos extracelulares abundantes e processos para suas producões e usos - Google Patents

Produtos extracelulares abundantes e processos para suas producões e usos

Info

Publication number
BR9608894A
BR9608894A BR9608894-0A BR9608894A BR9608894A BR 9608894 A BR9608894 A BR 9608894A BR 9608894 A BR9608894 A BR 9608894A BR 9608894 A BR9608894 A BR 9608894A
Authority
BR
Brazil
Prior art keywords
extracellular products
vaccines
abundant
processes
abundant extracellular
Prior art date
Application number
BR9608894-0A
Other languages
English (en)
Inventor
Marcus A Horwitz
Gunter Harth
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/447,398 external-priority patent/US6761894B1/en
Application filed by Univ California filed Critical Univ California
Publication of BR9608894A publication Critical patent/BR9608894A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

''PRODUTOS EXTRACELULARES ABUNDANTES E PROCESSOS PARA SUA PRODUçãO E USO" Vacinas à base de uma ou mais combinações de produtos extracelulares abundantes de agentes patogênicos e processos para os seus usos e produções são apresentadas. Os produtos extracelulares abundantes predominantes de um agente patogên ico alvo são selecionados independentemente das suas imunogenicidade moleculares absolutas e usados como vacinas para estimular uma resposta imunoprotetora em hospedeiros mamíferos contra a subsequente infecção pelo agente patogênico alvo. Os produtos extracelulares abundantes predominantes podem ser caracterizados e distinguidos pelo seus aminoácidos N-terminais respectivos, aminoácidos ou sequênciasde DNA. Como as vacinas podem compreender diferentes combinações dos produtos extracelulares das suas subunidades ou codificação de ácidos nucleicos, uma ampla variedade de composições imunoterapêuticas eficazes são fornecidas pela presente invenção. Além dos agentes infecciosos, as vacinas assim produzidas podem ser usadas para estimular uma resposta imunoeficaz contra agentes patogênicos intracelulares e em particular o Mycobacterium tuberculosis.
BR9608894-0A 1995-05-23 1996-05-23 Produtos extracelulares abundantes e processos para suas producões e usos BR9608894A (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/447,398 US6761894B1 (en) 1993-11-23 1995-05-23 Abundant extracellular products and methods for their production and use
US54592695A 1995-10-20 1995-10-20
US55114995A 1995-10-31 1995-10-31
US56835795A 1995-12-06 1995-12-06
PCT/US1996/007781 WO1996037219A1 (en) 1995-05-23 1996-05-23 Abundant extracellular products and methods for their production and use

Publications (1)

Publication Number Publication Date
BR9608894A true BR9608894A (pt) 1999-12-07

Family

ID=27503944

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9608894-0A BR9608894A (pt) 1995-05-23 1996-05-23 Produtos extracelulares abundantes e processos para suas producões e usos

Country Status (7)

Country Link
EP (1) EP0828510A1 (pt)
JP (1) JPH11506320A (pt)
AU (1) AU6024596A (pt)
BR (1) BR9608894A (pt)
CA (1) CA2222000C (pt)
NZ (1) NZ309945A (pt)
WO (1) WO1996037219A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6991797B2 (en) 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US6641814B1 (en) 1997-04-02 2003-11-04 Statens Serum Institut Nucleic acids fragments and polypeptide fragments derived from M. tuberculosis
AU6029898A (en) * 1997-01-21 1998-08-07 Regents Of The University Of California, The Abundant extracellular products and methods for their production and use
ATE370236T1 (de) * 1997-04-02 2007-09-15 Statens Seruminstitut Nukleinsäure- und polypeptidfragmente von m. tuberculosis
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
CA2292843A1 (en) * 1997-07-07 1999-01-21 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast
CA2319380A1 (en) * 1997-11-10 1999-05-20 Statens Serum Institut Nucleic acid fragments and polypeptide fragments derived from m. tuberculosis
FR2796397B1 (fr) * 1999-07-16 2006-09-01 Merial Sas Genes de calicivirus felin et vaccins notamment vaccins recombines
GB0003082D0 (en) * 2000-02-10 2000-03-29 Glaxo Group Ltd Vaccine
AU2001270031B2 (en) * 2000-06-22 2005-11-03 Wyeth Holdings Corporation QS-21 and IL-12 as an adjuvant combination
WO2002004018A2 (en) * 2000-07-10 2002-01-17 Colorado State University Research Foundation Mid-life vaccine and methods for boosting anti-mycobacterial immunity
CN102220357B (zh) 2004-11-16 2013-12-25 克鲁塞尔荷兰公司 包含重组病毒载体的多价疫苗
GB2433740A (en) * 2005-12-23 2007-07-04 Rapid Biosensor Systems Ltd Detection of tuberculosis infection
US9297803B2 (en) 2006-11-01 2016-03-29 Immport Therapeutics, Inc. Compositions and methods for immunodominant antigens
CN104271744B (zh) * 2011-12-22 2017-06-06 悉尼大学 分枝杆菌感染的预防和治疗

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5108745B1 (en) * 1988-08-16 1998-06-30 Univ California Tuberculosis and legionellosis vaccines and methods for their production
US5330754A (en) * 1992-06-29 1994-07-19 Archana Kapoor Membrane-associated immunogens of mycobacteria
JPH09505588A (ja) * 1993-11-23 1997-06-03 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 多くの細胞外生成物及びそれらの製造法並びに使用
WO1996005223A1 (en) * 1994-08-12 1996-02-22 The Regents Of The University Of California Abundant extracellular products and methods for their production and use

Also Published As

Publication number Publication date
JPH11506320A (ja) 1999-06-08
EP0828510A1 (en) 1998-03-18
NZ309945A (en) 2001-04-27
MX9709053A (es) 1998-10-31
WO1996037219A1 (en) 1996-11-28
CA2222000A1 (en) 1996-11-28
CA2222000C (en) 2012-03-20
AU6024596A (en) 1996-12-11

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]