BR9610530A - Derivados de acriloilguanidina substituíduo com heteroarila e composiç es farmacêuticas contendo os mesmos - Google Patents
Derivados de acriloilguanidina substituíduo com heteroarila e composiç es farmacêuticas contendo os mesmosInfo
- Publication number
- BR9610530A BR9610530A BR9610530A BR9610530A BR9610530A BR 9610530 A BR9610530 A BR 9610530A BR 9610530 A BR9610530 A BR 9610530A BR 9610530 A BR9610530 A BR 9610530A BR 9610530 A BR9610530 A BR 9610530A
- Authority
- BR
- Brazil
- Prior art keywords
- same
- pharmaceutical compositions
- compositions containing
- heteroaryl substituted
- derivatives
- Prior art date
Links
- 125000001072 heteroaryl group Chemical group 0.000 title 1
- UWICDWBEVIDNNJ-UHFFFAOYSA-N n-(diaminomethylidene)prop-2-enamide Chemical class NC(=N)NC(=O)C=C UWICDWBEVIDNNJ-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24171695 | 1995-09-20 | ||
| PCT/JP1996/002696 WO1997011055A1 (en) | 1995-09-20 | 1996-09-19 | Heteroaryl-substituted acryloylguanidine derivatives and medicinal composition thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9610530A true BR9610530A (pt) | 1999-07-06 |
Family
ID=17078479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9610530A BR9610530A (pt) | 1995-09-20 | 1996-09-19 | Derivados de acriloilguanidina substituíduo com heteroarila e composiç es farmacêuticas contendo os mesmos |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0861831A4 (pt) |
| KR (1) | KR19990063589A (pt) |
| CN (1) | CN1196721A (pt) |
| AU (1) | AU702092B2 (pt) |
| BR (1) | BR9610530A (pt) |
| CA (1) | CA2232497A1 (pt) |
| CZ (1) | CZ84098A3 (pt) |
| HU (1) | HUP9901336A3 (pt) |
| NO (1) | NO981241L (pt) |
| PL (1) | PL326033A1 (pt) |
| SK (1) | SK35198A3 (pt) |
| WO (1) | WO1997011055A1 (pt) |
| ZA (1) | ZA967800B (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0854721B1 (en) * | 1995-08-02 | 2001-10-24 | Smithkline Beecham Corporation | Endothelin receptor antagonists |
| JP3652708B2 (ja) * | 1997-03-06 | 2005-05-25 | トーアエイヨー株式会社 | シクロアルカ［ｂ］ピリジン−３−カルボニルグアニジン誘導体、その製造法およびそれを含有する医薬品 |
| US6498187B1 (en) * | 1999-08-23 | 2002-12-24 | Smithkline Beecham Corporation | Fatty acid synthase inhibitors |
| ATE341343T1 (de) | 2000-12-26 | 2006-10-15 | Sankyo Co | Medizinische zusammensetzungen mit diuretischem und die insulinresistenz verbesserndem mittel |
| ES2332659T3 (es) | 2004-06-16 | 2010-02-10 | Wyeth | Derivados de amino-5,5-difenilimidazolona para la inhibicion de beta-secretasa. |
| ATE423121T1 (de) | 2004-06-16 | 2009-03-15 | Wyeth Corp | Diphenylimidazopyrimidin- und -imidazolamine als b-sekretase-inhibitoren |
| CN101103034A (zh) | 2005-01-14 | 2008-01-09 | 惠氏公司 | 抑制β-分泌酶的氨基-咪唑酮 |
| MX2007009313A (es) | 2005-02-01 | 2007-09-12 | Wyeth Corp | Amino-piridinas como inhibidores de ????-secretasa. |
| BRPI0606902A2 (pt) | 2005-02-14 | 2009-07-28 | Wyeth Corp | composto; método para o tratamento de uma doença ou distúrbio associado a atividade excessiva de bace em um paciente que dele necessite; método para modular a atividade de bace; composição farmacêutica |
| WO2006088694A1 (en) | 2005-02-14 | 2006-08-24 | Wyeth | SUBSTITUTED THIENYL AND FURYL ACYLGUANIDINES AS β-SECRETASE MODULATORS |
| TW200738683A (en) | 2005-06-30 | 2007-10-16 | Wyeth Corp | Amino-5-(5-membered)heteroarylimidazolone compounds and the use thereof for β-secretase modulation |
| EP1896448A1 (en) | 2005-06-30 | 2008-03-12 | Wyeth | AMINO-5-(6-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR ß-SECRETASE MODULATION |
| KR20080050430A (ko) | 2005-09-26 | 2008-06-05 | 와이어쓰 | 베타-세크레타제 (ｂａｃｅ) 억제제로서아미노-5-[4-(디플루오로메톡시)페닐]-5-페닐이미다졸론화합물 |
| WO2007100536A1 (en) | 2006-02-24 | 2007-09-07 | Wyeth | DIHYDROSPIRO[DIBENZO[A,D][7]ANNULENE-5,4'-IMIDAZOL] COMPOUNDS FOR THE INHIBITION OF β-SECRETASE |
| US7700606B2 (en) | 2006-08-17 | 2010-04-20 | Wyeth Llc | Imidazole amines as inhibitors of β-secretase |
| CL2008000791A1 (es) | 2007-03-23 | 2008-05-30 | Wyeth Corp | Compuestos derivados de 2-amino-5-(4-difluorometoxi-fenil)-5-fenil-imidazolidin-4-ona; composicion farmaceutica que comprende a dichos compuestos; y su uso en el tratamiento de una enfermedad asociada con la actividad bace excesiva, tales como enferm |
| WO2018065288A1 (de) | 2016-10-07 | 2018-04-12 | Bayer Cropscience Aktiengesellschaft | 2-[2-phenyl-1-(sulfonylmethyl)vinyl]-imidazo[4,5-b]pyridin-derivate und verwandte verbindungen als schädlingsbekämpfungsmittel im pflanzenschutz |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3929582A1 (de) | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
| EP0556674B1 (de) * | 1992-02-15 | 1996-06-19 | Hoechst Aktiengesellschaft | 3,5-Substituierte Benzoylguanidine, mit antiarrythmischer Wirkung und inhibierender Wirkung auf die Proliferationen von Zellen |
| JP3162572B2 (ja) * | 1993-04-28 | 2001-05-08 | 住友製薬株式会社 | インドロイルグアニジン誘導体 |
| US5401758A (en) * | 1993-10-07 | 1995-03-28 | Bristol-Myers Squibb Company | Pyridinyl cyanoguanidine compounds |
| DE4430861A1 (de) * | 1994-08-31 | 1996-03-07 | Merck Patent Gmbh | Heterocyclyl-benzoylguanidine |
| JPH0959245A (ja) * | 1995-08-25 | 1997-03-04 | Yamanouchi Pharmaceut Co Ltd | Ｎ−（２−プロペノイル）グアニジン誘導体 |
-
1996
- 1996-09-16 ZA ZA967800A patent/ZA967800B/xx unknown
- 1996-09-19 CN CN96196999A patent/CN1196721A/zh active Pending
- 1996-09-19 PL PL96326033A patent/PL326033A1/xx unknown
- 1996-09-19 EP EP96931252A patent/EP0861831A4/en not_active Withdrawn
- 1996-09-19 AU AU70007/96A patent/AU702092B2/en not_active Ceased
- 1996-09-19 SK SK351-98A patent/SK35198A3/sk unknown
- 1996-09-19 WO PCT/JP1996/002696 patent/WO1997011055A1/ja not_active Ceased
- 1996-09-19 HU HU9901336A patent/HUP9901336A3/hu unknown
- 1996-09-19 CA CA002232497A patent/CA2232497A1/en not_active Abandoned
- 1996-09-19 BR BR9610530A patent/BR9610530A/pt not_active Application Discontinuation
- 1996-09-19 KR KR1019980702028A patent/KR19990063589A/ko not_active Withdrawn
- 1996-09-19 CZ CZ98840A patent/CZ84098A3/cs unknown
-
1998
- 1998-03-19 NO NO981241A patent/NO981241L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO981241L (no) | 1998-05-20 |
| MX9802238A (es) | 1998-08-30 |
| NO981241D0 (no) | 1998-03-19 |
| EP0861831A4 (en) | 1998-11-11 |
| SK35198A3 (en) | 1999-06-11 |
| ZA967800B (en) | 1997-04-03 |
| AU702092B2 (en) | 1999-02-11 |
| AU7000796A (en) | 1997-04-09 |
| WO1997011055A1 (en) | 1997-03-27 |
| CZ84098A3 (cs) | 1998-09-16 |
| EP0861831A1 (en) | 1998-09-02 |
| KR19990063589A (ko) | 1999-07-26 |
| CA2232497A1 (en) | 1997-03-27 |
| HUP9901336A2 (hu) | 1999-08-30 |
| PL326033A1 (en) | 1998-08-17 |
| CN1196721A (zh) | 1998-10-21 |
| HUP9901336A3 (en) | 2000-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law |