BR9704352A - Compostos tricíclicos de piperidinilamino como antagonistas da substáncia p - Google Patents

Compostos tricíclicos de piperidinilamino como antagonistas da substáncia p

Info

Publication number: BR9704352A
Authority: BR; Brazil
Prior art keywords: chem; alkoxy; piperidinylamino; antagonists; substance
Prior art date: 1996-08-14

Application number

BR9704352A

Other languages

English (en)

Inventor

Hiroaki Wakabayashi

Hiroki Koike

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-14

Filing date

1997-08-13

Publication date

1999-01-05

1997-08-13 Application filed by Pfizer filed Critical Pfizer

1999-01-05 Publication of BR9704352A publication Critical patent/BR9704352A/pt

Links

150000001875 compounds Chemical class 0.000 title abstract 3
-1 Piperidinylamino Chemical group 0.000 title 1
239000005557 antagonist Substances 0.000 title 1
ADNPLDHMAVUMIW-CUZNLEPHSA-N substance P Chemical compound C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CCCN=C(N)N)C1=CC=CC=C1 ADNPLDHMAVUMIW-CUZNLEPHSA-N 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
210000003169 central nervous system Anatomy 0.000 abstract 2
208000035475 disorder Diseases 0.000 abstract 2
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
241000590002 Helicobacter pylori Species 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
208000019695 Migraine disease Diseases 0.000 abstract 1
208000002193 Pain Diseases 0.000 abstract 1
206010042496 Sunburn Diseases 0.000 abstract 1
206010046543 Urinary incontinence Diseases 0.000 abstract 1
206010047700 Vomiting Diseases 0.000 abstract 1
230000002411 adverse Effects 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000033115 angiogenesis Effects 0.000 abstract 1
208000010643 digestive system disease Diseases 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000018685 gastrointestinal system disease Diseases 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
229940037467 helicobacter pylori Drugs 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
208000027866 inflammatory disease Diseases 0.000 abstract 1
206010027599 migraine Diseases 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

BR9704352A 1996-08-14 1997-08-13 Compostos tricíclicos de piperidinilamino como antagonistas da substáncia p BR9704352A (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IB9600798		1996-08-14

Publications (1)

Publication Number	Publication Date
BR9704352A true BR9704352A (pt)	1999-01-05

Family

ID=11004463

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9704352A BR9704352A (pt)	1996-08-14	1997-08-13	Compostos tricíclicos de piperidinilamino como antagonistas da substáncia p

Country Status (10)

Country	Link
US (2)	US5972930A (pt)
EP (1)	EP0824100B1 (pt)
AT (1)	ATE196470T1 (pt)
BR (1)	BR9704352A (pt)
CA (1)	CA2212784C (pt)
DE (1)	DE69703143T2 (pt)
DK (1)	DK0824100T3 (pt)
ES (1)	ES2150739T3 (pt)
GR (1)	GR3034775T3 (pt)
MX (1)	MX9706196A (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2409582C2 (ru) *	2004-08-31	2011-01-20	Глэксо Груп Лимитед	Конденсированные трициклические производные для лечения психотических расстройств
PE20060653A1 (es) *	2004-08-31	2006-09-27	Glaxo Group Ltd	Derivados triciclicos condensados como moduladores del receptor 5-ht1
US10154988B2 (en)	2012-11-14	2018-12-18	The Johns Hopkins University	Methods and compositions for treating schizophrenia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5232929A (en) *	1990-11-28	1993-08-03	Pfizer Inc.	3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
SK282203B6 (sk) *	1991-06-20	2001-12-03	Pfizer Inc.	Fluoroalkoxybenzylamínové deriváty heterocyklov obsahujúcich dusík, spôsob ich prípravy, medziprodukty, spôsob prípravy medziproduktov, použitie a farmaceutický prostriedok
JP2909214B2 (ja) *	1992-08-19	1999-06-23	フアイザー・インコーポレイテツド	置換ベンジルアミノ窒素含有非芳香族複素環化合物
IS4208A (is) *	1993-09-22	1995-03-23	Glaxo Group Limited	3-(tetrazólýl-benzyl)amínó-piperadidín afleiður
JP3042894B2 (ja) *	1995-07-07	2000-05-22	ファイザー製薬株式会社	サブスタンスｐアンタゴニストとしての置換ベンゾラクタム化合物
TW340842B (en) *	1995-08-24	1998-09-21	Pfizer	Substituted benzylaminopiperidine compounds

1996
- 1996-08-14 MX MX9706196A patent/MX9706196A/es not_active IP Right Cessation
1997
- 1997-08-07 US US08/907,374 patent/US5972930A/en not_active Expired - Fee Related
- 1997-08-08 DK DK97306054T patent/DK0824100T3/da active
- 1997-08-08 EP EP97306054A patent/EP0824100B1/en not_active Expired - Lifetime
- 1997-08-08 AT AT97306054T patent/ATE196470T1/de not_active IP Right Cessation
- 1997-08-08 ES ES97306054T patent/ES2150739T3/es not_active Expired - Lifetime
- 1997-08-08 DE DE69703143T patent/DE69703143T2/de not_active Expired - Fee Related
- 1997-08-12 CA CA002212784A patent/CA2212784C/en not_active Expired - Fee Related
- 1997-08-13 BR BR9704352A patent/BR9704352A/pt not_active Application Discontinuation
1999
- 1999-07-12 US US09/351,011 patent/US6143767A/en not_active Expired - Fee Related
2000
- 2000-11-08 GR GR20000402464T patent/GR3034775T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
US6143767A (en)	2000-11-07
ES2150739T3 (es)	2000-12-01
DE69703143T2 (de)	2001-03-22
CA2212784A1 (en)	1998-02-14
US5972930A (en)	1999-10-26
DE69703143D1 (de)	2000-10-26
CA2212784C (en)	2001-02-27
EP0824100A1 (en)	1998-02-18
GR3034775T3 (en)	2001-02-28
EP0824100B1 (en)	2000-09-20
MX9706196A (es)	1998-02-28
ATE196470T1 (de)	2000-10-15
DK0824100T3 (da)	2000-11-20

Legal Events

Date	Code	Title	Description
2002-06-11	FB34	Technical and formal requirements: requirement - article 34 of industrial property law
2007-04-27	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2007-12-18	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2008-06-03	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, NAO ATENDE AO DISPOSTO DO ART. 8O E 13 DA LPI 9279/96

Publication	Publication Date	Title
MY114800A (en)	2003-01-31	Substituted benzylaminopiperidine compounds
KR100366902B1 (ko)	2003-01-09	섭스턴스 ｐ 길항제로서 피페리디닐아미노메틸트리플루오로메틸 시클릭 에테르 화합물
ATE131479T1 (de)	1995-12-15	1,3-dihydro-2h-imidano 4,5-b-quinolin-2-ein derivate als phosphodiestenase hemmer
DE60138732D1 (de)	2009-06-25	Muscarin-rezeptor-agonisten
PT1259489E (pt)	2006-08-31	Compostos azapoliciclicos condensados con arilo.
ATE217623T1 (de)	2002-06-15	Azindolethylaminderivate als nikotin-acetylcholin-rezeptor bindung verbindungen
LU92113I2 (fr)	2013-02-12	Perampanel et ses dérivés pharmaceutiquement acceptables (FYCOMPA)
ATE225770T1 (de)	2002-10-15	Difluoroprostaglandin-derivate und ihre anwendung
ES2180693T3 (es)	2003-02-16	3-((bencil 5-sustituido)amino)-2-fenilpiperidinas como antagonistas de la sustancia p.
DK0824100T3 (da)	2000-11-20	Tricykliske piperidinylaminoforbindelser som substans P-antagonister
SE8505369D0 (sv)	1985-11-13	New thienopyridine derivatives, a process of preparation thereof and therapeutic compositions containing the same
DE69703725D1 (de)	2001-01-25	Tetrazolyl-substituierte Chinuclidine als Substanz P Antagonisten
ES2141134T3 (es)	2000-03-16	Derivados de carbamoil pirrolidona para el tratamiento de la depresion y de los trastornos cerebrovasculares.
TH28832B (th)	1998-06-10	สารปะกอบเบนซิลอะมิโนไพเพอริดินที่ถูกแทนที่
IT1248525B (it)	1995-01-19	Derivati dell'eseridina utili per il trattamento delle malattie associate a disordini colinergici, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.