BR9705143A - Derivados de 10,13,15-trioxatriciclo [9.2.1.1(9.6)] -pentadecanona, processo para a sua preparação e medicamentos que contém estes compostos - Google Patents

Derivados de 10,13,15-trioxatriciclo [9.2.1.1(9.6)] -pentadecanona, processo para a sua preparação e medicamentos que contém estes compostos

Info

Publication number
BR9705143A
BR9705143A BR9705143-8A BR9705143A BR9705143A BR 9705143 A BR9705143 A BR 9705143A BR 9705143 A BR9705143 A BR 9705143A BR 9705143 A BR9705143 A BR 9705143A
Authority
BR
Brazil
Prior art keywords
derivatives
preparation
pentadecanone
compounds
trioxatriciclo
Prior art date
Application number
BR9705143-8A
Other languages
English (en)
Inventor
Ulf Preuschoff
Christian Eeckhout
Dagmar Hoeltje
Emil Finner
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of BR9705143A publication Critical patent/BR9705143A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Patente de Invenção: <B>"DERIVADOS DE 10, 13, 15-TRIOXATRICICLO[9.2.1.1.9.6]-PENTADECANONA, PROCESSO PARA A SUA PREPARAçãO E MEDICAMENTOS QUE CONTêM ESTES COMPOSTOS"<D>. Descrevem-se derivados de N-desmetil-N-isopropil-eritromicina-A-espiroacetal restringidos no anel com propriedades agonísticas da motilina gastrintestinalmente ativos e a sua preparação.
BR9705143-8A 1996-10-24 1997-10-24 Derivados de 10,13,15-trioxatriciclo [9.2.1.1(9.6)] -pentadecanona, processo para a sua preparação e medicamentos que contém estes compostos BR9705143A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19644195A DE19644195A1 (de) 1996-10-24 1996-10-24 10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
BR9705143A true BR9705143A (pt) 2000-12-12

Family

ID=7809858

Family Applications (2)

Application Number Title Priority Date Filing Date
BR9705143-8A BR9705143A (pt) 1996-10-24 1997-10-24 Derivados de 10,13,15-trioxatriciclo [9.2.1.1(9.6)] -pentadecanona, processo para a sua preparação e medicamentos que contém estes compostos
BR9705157-8A BR9705157A (pt) 1996-10-24 1997-10-24 Derivados de 10,13,15-trioxatriciclo[9.2.1. 9.6]-pentadecanona, processo para a sua preparação e medicamentos que contêm estes compostos

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR9705157-8A BR9705157A (pt) 1996-10-24 1997-10-24 Derivados de 10,13,15-trioxatriciclo[9.2.1. 9.6]-pentadecanona, processo para a sua preparação e medicamentos que contêm estes compostos

Country Status (26)

Country Link
US (1) US5912235A (pt)
EP (1) EP0838469B1 (pt)
JP (1) JP4175682B2 (pt)
KR (1) KR100466495B1 (pt)
CN (1) CN1093133C (pt)
AR (1) AR009809A1 (pt)
AT (1) ATE211745T1 (pt)
AU (1) AU726092B2 (pt)
BR (2) BR9705143A (pt)
CA (1) CA2219311C (pt)
CZ (1) CZ291768B6 (pt)
DE (2) DE19644195A1 (pt)
DK (1) DK0838469T3 (pt)
DZ (1) DZ2322A1 (pt)
ES (1) ES2170318T3 (pt)
HU (1) HU222540B1 (pt)
IL (1) IL121969A (pt)
MX (1) MX9707974A (pt)
NO (1) NO308362B1 (pt)
NZ (1) NZ328979A (pt)
PL (1) PL184693B1 (pt)
PT (1) PT838469E (pt)
RU (1) RU2181727C2 (pt)
SK (1) SK283114B6 (pt)
UA (1) UA44310C2 (pt)
ZA (1) ZA979059B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4968997A (en) * 1996-11-26 1998-06-22 Chugai Seiyaku Kabushiki Kaisha 13-membered ring macrolide compounds, medicine containing the same, and process for producing the same
CA2386828C (en) 2000-08-17 2006-01-24 The Kitasato Institute Novel pseudoerythromycin derivatives
JP2003007917A (ja) * 2001-06-19 2003-01-10 Sanyo Electric Co Ltd 回路装置の製造方法
US6986882B2 (en) * 2002-01-17 2006-01-17 Astrazeneca Ab Therapy for functional dyspepsia
CA2528375C (en) 2003-06-18 2013-11-19 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor
GB0611907D0 (en) 2006-06-15 2006-07-26 Glaxo Group Ltd Compounds
EP1902022A1 (en) 2005-07-12 2008-03-26 Glaxo Group Limited Piperazine heteroaryl derivates as gpr38 agonists
MY150098A (en) * 2005-07-26 2013-11-29 Glaxo Group Ltd Benzylpiperazine derivates and their medical use
NZ568763A (en) * 2005-12-08 2010-04-30 Pfizer Method for demethylating the 3'-dimethylamino group of erythromycin compounds
PL2041093T3 (pl) 2006-06-28 2010-09-30 Glaxo Group Ltd Pochodne piperazynylowe użyteczne w leczeniu zaburzeń, którym pośredniczy receptor GPR38
EP2431380A3 (en) 2006-09-11 2013-07-03 Tranzyme Pharma, Inc. Macrocyclic antagonist of the motilin receptor for treatment of gastrointestinal dysmotility disorders
ES2401467T3 (es) * 2006-12-05 2013-04-19 Bristol-Myers Squibb Company Polimorfos de motilida
EP2401268B1 (en) 2009-02-27 2015-07-29 RaQualia Pharma Inc Oxyindole derivatives with motilin receptor agonistic activity
TWI662967B (zh) * 2013-03-25 2019-06-21 日商志瑞亞新藥工業股份有限公司 食後期之胃運動亢進劑

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725385A (en) * 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
DE4200145A1 (de) * 1992-01-07 1993-07-08 Kali Chemie Pharma Gmbh 7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
SK283114B6 (sk) 2003-02-04
CZ291768B6 (cs) 2003-05-14
HK1010885A1 (en) 1999-07-02
PL184693B1 (pl) 2002-12-31
AU726092B2 (en) 2000-11-02
CA2219311C (en) 2007-09-04
KR100466495B1 (ko) 2005-05-27
HUP9701660A2 (hu) 1998-05-28
EP0838469A1 (de) 1998-04-29
CN1093133C (zh) 2002-10-23
NZ328979A (en) 1998-10-28
MX9707974A (es) 1998-04-30
PL322802A1 (en) 1998-04-27
DZ2322A1 (fr) 2002-12-28
UA44310C2 (uk) 2002-02-15
HU222540B1 (hu) 2003-08-28
US5912235A (en) 1999-06-15
JP4175682B2 (ja) 2008-11-05
ATE211745T1 (de) 2002-01-15
NO974934D0 (no) 1997-10-24
AU4278897A (en) 1998-04-30
DK0838469T3 (da) 2002-03-18
ZA979059B (en) 1998-05-07
CA2219311A1 (en) 1998-04-24
BR9705157A (pt) 1999-09-28
EP0838469B1 (de) 2002-01-09
CN1186808A (zh) 1998-07-08
PT838469E (pt) 2002-05-31
IL121969A (en) 2000-06-29
DE59705964D1 (de) 2002-02-14
RU2181727C2 (ru) 2002-04-27
AR009809A1 (es) 2000-05-03
ES2170318T3 (es) 2002-08-01
IL121969A0 (en) 1998-03-10
JPH10130297A (ja) 1998-05-19
NO974934L (no) 1998-04-27
CZ310697A3 (cs) 1998-06-17
NO308362B1 (no) 2000-09-04
SK141997A3 (en) 1998-05-06
DE19644195A1 (de) 1998-04-30
HU9701660D0 (en) 1997-12-29
KR19980032626A (ko) 1998-07-25
HUP9701660A3 (en) 1998-08-28

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time