BR9707936A - Método para aperfeiçoamento de imagens ultra-saÈnicas, composição formada de imagem através de ultra-som e método para a fabricação de um micropartìcula formada por um polìmero biocompatìvel com ecogenicidade aumentada. - Google Patents

Método para aperfeiçoamento de imagens ultra-saÈnicas, composição formada de imagem através de ultra-som e método para a fabricação de um micropartìcula formada por um polìmero biocompatìvel com ecogenicidade aumentada.

Info

Publication number
BR9707936A
BR9707936A BR9707936-7A BR9707936A BR9707936A BR 9707936 A BR9707936 A BR 9707936A BR 9707936 A BR9707936 A BR 9707936A BR 9707936 A BR9707936 A BR 9707936A
Authority
BR
Brazil
Prior art keywords
biocompatible polymer
ultrasonic images
manufacture
microparticle
ultrasound imaging
Prior art date
Application number
BR9707936-7A
Other languages
English (en)
Other versions
BR9707936B1 (pt
Inventor
Howard Bernstein
Ann Julie
Edith Mathiowitz
Hernry T Brush
Richard E Wing
Original Assignee
Acusphere Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27086474&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9707936(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/611,248 external-priority patent/US5611344A/en
Application filed by Acusphere Inc filed Critical Acusphere Inc
Publication of BR9707936A publication Critical patent/BR9707936A/pt
Publication of BR9707936B1 publication Critical patent/BR9707936B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/481—Diagnostic techniques involving the use of contrast agents, e.g. microbubbles introduced into the bloodstream
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Acoustics & Sound (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)

Abstract

<B>"MéTODO PARA APERFEIçOAMENTO DE IMAGENS ULTRA-SÈNICAS, COMPOSIçãO FORMADORA DE IMAGEM ATRAVéS DE ULTRA-SOM E MéTODO PARA FABRICAçãO DE UMA MICROPARTìCULA FORMADA POR UM POLìMERO BIOCOMPATìVEL COM ECOGENICIDAD AUMENTADA"<D>. Foi descoberto que a incorporação de gases fluorados, especialmente um perfluorocarbono como octafluoropropano, em micropartículas poliméricas sintéticas melhora a ecogenicidade quando comparadas com micropartículas contendo ar. O perfluorocarbono é fabricado com um diâmetro adequado para o tecido alvo cuja imagem será formada, por exemplo, para administração via intravenosa ou oral. Em um modelo, micropartículas bioaderentes são produzidas para melhorar a formação de imagens de superfícies mucosas.
BRPI9707936-7A 1996-03-05 1997-02-27 composiÇço formadora de imagem atravÉs de ultra-som. BR9707936B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US611,248 1996-03-05
US08/611,248 US5611344A (en) 1996-03-05 1996-03-05 Microencapsulated fluorinated gases for use as imaging agents
US08/745,676 US5853698A (en) 1996-03-05 1996-11-08 Method for making porous microparticles by spray drying
US745,676 1996-11-08
PCT/US1997/003117 WO1997032609A2 (en) 1996-03-05 1997-02-27 Microencapsulated fluorinated gases for use as imaging agents

Publications (2)

Publication Number Publication Date
BR9707936A true BR9707936A (pt) 2000-01-04
BR9707936B1 BR9707936B1 (pt) 2010-12-14

Family

ID=27086474

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9707936-7A BR9707936B1 (pt) 1996-03-05 1997-02-27 composiÇço formadora de imagem atravÉs de ultra-som.

Country Status (20)

Country Link
US (1) US6132699A (pt)
EP (1) EP0904113B1 (pt)
JP (1) JP3178724B2 (pt)
AT (1) ATE266426T1 (pt)
AU (1) AU721209B2 (pt)
BR (1) BR9707936B1 (pt)
CA (1) CA2247151C (pt)
CZ (1) CZ281298A3 (pt)
DE (1) DE69729088T2 (pt)
DK (1) DK0904113T3 (pt)
ES (1) ES2221687T3 (pt)
HU (1) HU226714B1 (pt)
ID (1) ID17753A (pt)
IL (1) IL126073A (pt)
MY (1) MY124549A (pt)
NO (1) NO312940B1 (pt)
NZ (1) NZ331460A (pt)
PT (1) PT904113E (pt)
TW (1) TWI246426B (pt)
WO (1) WO1997032609A2 (pt)

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DE102008045152A1 (de) * 2008-07-09 2010-01-14 Universität Duisburg-Essen Künstliche Sauerstoffträger und ihre Verwendung
KR101061224B1 (ko) * 2008-10-08 2011-08-31 포항공과대학교 산학협력단 Ｘ 선을 이용한 유동정보 측정용 캡슐
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Also Published As

Publication number Publication date
JP2000501745A (ja) 2000-02-15
AU2139297A (en) 1997-09-22
AU721209B2 (en) 2000-06-29
EP0904113B1 (en) 2004-05-12
DK0904113T3 (da) 2004-08-30
NO984089L (no) 1998-09-04
NZ331460A (en) 1998-12-23
NO312940B1 (no) 2002-07-22
HUP9902897A2 (hu) 2000-01-28
EP0904113A2 (en) 1999-03-31
DE69729088D1 (de) 2004-06-17
CZ281298A3 (cs) 1999-01-13
WO1997032609A3 (en) 1998-01-29
HUP9902897A3 (en) 2000-03-28
CA2247151C (en) 2008-05-20
WO1997032609A2 (en) 1997-09-12
BR9707936B1 (pt) 2010-12-14
CA2247151A1 (en) 1997-09-12
NO984089D0 (no) 1998-09-04
PT904113E (pt) 2004-09-30
DE69729088T2 (de) 2005-05-12
ATE266426T1 (de) 2004-05-15
JP3178724B2 (ja) 2001-06-25
IL126073A0 (en) 1999-05-09
MY124549A (en) 2006-06-30
HK1020428A1 (en) 2000-04-20
US6132699A (en) 2000-10-17
IL126073A (en) 2002-02-10
TWI246426B (en) 2006-01-01
ID17753A (id) 1998-01-22
HU226714B1 (en) 2009-07-28
ES2221687T3 (es) 2005-01-01

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