BR9711273A - 1,2,3,4- Tetraidro-2-dibenzofuranaminas substituidas e 2- aminociclohepta b benzofuranos - Google Patents

1,2,3,4- Tetraidro-2-dibenzofuranaminas substituidas e 2- aminociclohepta b benzofuranos

Info

Publication number: BR9711273A
Authority: BR; Brazil
Prior art keywords: aminocyclohepta; dibenzofuranamines; benzofurans; substituted tetrahydro; substituted
Prior art date: 1996-08-28

Application number

BR9711273A

Other languages

English (en)

Inventor

Michael Edward Flaugh

Junior Daniel Anton Kiefer

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-28

Filing date

1997-08-25

Publication date

1999-08-17

1997-08-25 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1999-08-17 Publication of BR9711273A publication Critical patent/BR9711273A/pt

Links

JCFPKIOSTZEMSZ-UHFFFAOYSA-N 1,2,3,4-tetrahydrodibenzofuran-2-amine Chemical class O1C2=CC=CC=C2C2=C1CCC(N)C2 JCFPKIOSTZEMSZ-UHFFFAOYSA-N 0.000 title 1
150000001907 coumarones Chemical class 0.000 title 1
GJUCAWYIAWECBW-UHFFFAOYSA-N 1h-cyclohepta[b][1]benzofuran-2-amine Chemical class O1C2=CC=CC=CC2=C2C1=CC=C(N)C2 GJUCAWYIAWECBW-UHFFFAOYSA-N 0.000 abstract 1
102100036311 5-hydroxytryptamine receptor 1F Human genes 0.000 abstract 1
101710138086 5-hydroxytryptamine receptor 1F Proteins 0.000 abstract 1
239000000556 agonist Substances 0.000 abstract 1
-1 substituted-2-amino-1,2,3,4-tetrahydrodibenzofurans Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Furan Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Polyethers (AREA)

BR9711273A 1996-08-28 1997-08-25 1,2,3,4- Tetraidro-2-dibenzofuranaminas substituidas e 2- aminociclohepta b benzofuranos BR9711273A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US2474596P	1996-08-28	1996-08-28
PCT/US1997/014938 WO1998008502A1 (en)	1996-08-28	1997-08-25	SUBSTITUTED 1,2,3,4-TETRAHYDRO-2-DIBENZOFURANAMINES AND 2-AMINOCYCLOHEPTA[b]BENZOFURANS

Publications (1)

Publication Number	Publication Date
BR9711273A true BR9711273A (pt)	1999-08-17

Family

ID=21822177

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9711273A BR9711273A (pt)	1996-08-28	1997-08-25	1,2,3,4- Tetraidro-2-dibenzofuranaminas substituidas e 2- aminociclohepta b benzofuranos

Country Status (23)

Country	Link
EP (1)	EP0929299B1 (pt)
JP (1)	JP2000516957A (pt)
KR (1)	KR20000035942A (pt)
CN (1)	CN1228695A (pt)
AT (1)	ATE251457T1 (pt)
AU (1)	AU741324B2 (pt)
BR (1)	BR9711273A (pt)
CA (1)	CA2264267A1 (pt)
CZ (1)	CZ64499A3 (pt)
DE (1)	DE69725459T2 (pt)
DK (1)	DK0929299T3 (pt)
EA (1)	EA001912B1 (pt)
ES (1)	ES2208948T3 (pt)
HU (1)	HUP9902901A3 (pt)
IL (1)	IL128500A (pt)
NO (1)	NO990849D0 (pt)
NZ (1)	NZ334031A (pt)
PL (1)	PL331882A1 (pt)
PT (1)	PT929299E (pt)
TR (1)	TR199900430T2 (pt)
UA (1)	UA48245C2 (pt)
WO (1)	WO1998008502A1 (pt)
YU (1)	YU10499A (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA52778C2 (uk)	1997-10-10	2003-01-15	Янссен Фармацевтика Н.В.	Галогенозаміщені тетрациклічні похідні тетрагідрофурану, спосіб їх отримання та композиція на їх основі
TWI263497B (en)	2002-03-29	2006-10-11	Lilly Co Eli	Pyridinoylpiperidines as 5-HT1F agonists
MXPA05011223A (es)	2003-04-18	2006-01-26	Lilly Co Eli	Compuestos de (piperidiniloxi)fenilo, (piperidiniloxi)piridinilo, (piperidinilsulfanil)fenilo y (piperidinilsulfanil)piridinilo como agonistas 5-htif.
UA82711C2 (en)	2003-09-12	2008-05-12	Эли Лилли Энд Компани	Substituted 2-carbonylamino-6-piperidinaminopyridines and substituted 1-carbonylamino-3-piperidinaminobenzenes as 5-ht1f agonists
DE602004008338T2 (de)	2003-12-17	2008-05-29	Eli Lilly And Co., Indianapolis	Substituierte (4-aminocyclohexen-1-yl) phenyl and (4-aminocyclohexen-1-yl) pyridinyl verbindungen als 5-ht1f agonisten
CN1318411C (zh) *	2005-03-21	2007-05-30	中国海洋大学	氢化轮枝霉酮类化合物及其制备方法和用途
PL2413933T5 (pl)	2009-04-02	2021-10-18	Colucid Pharmaceuticals, Inc.	2,4,6-trifluoro-N-[6-(1-metylopiperydyno-4-karbonylo)pirydyn-2-ylo]benzamid do leczenia migreny drogą doustną lub dożylną
US8697876B2 (en)	2010-04-02	2014-04-15	Colucid Pharmaceuticals, Inc.	Compositions and methods of synthesis of pyridinolypiperidine 5-HT1F agonists
CN102887880B (zh) *	2012-08-20	2014-10-29	东南大学	二苯并呋喃衍生物及其制备方法与用途
TWI826514B (zh)	2018-09-04	2023-12-21	美商美國禮來大藥廠	用於預防偏頭痛之拉米迪坦(lasmiditan)長期夜間投藥
TWI776175B (zh)	2019-07-09	2022-09-01	美商美國禮來大藥廠	大規模製備2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺半琥珀酸鹽的方法及中間體，以及2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺醋酸鹽之製備

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4668690A (en) *	1985-12-30	1987-05-26	Hoechst Roussel Pharmaceuticals Inc.	1,2,3,4,4a,9b-hexahydro-4a-aminoalkyldibenzofurans useful as analgesics, anticonvulsants or antidepressants
US5521196A (en) *	1994-10-05	1996-05-28	Eli Lilly And Company	5-HT1F agonists for the treatment of migraine
US5698571A (en) *	1994-10-05	1997-12-16	Eli Lilly And Company	5-HT1F mediated inhibition of neurogenic meningeal extravasation: a method for the treatment of migraine

1997
- 1997-08-25 BR BR9711273A patent/BR9711273A/pt not_active IP Right Cessation
- 1997-08-25 TR TR1999/00430T patent/TR199900430T2/xx unknown
- 1997-08-25 EP EP97938585A patent/EP0929299B1/en not_active Expired - Lifetime
- 1997-08-25 HU HU9902901A patent/HUP9902901A3/hu unknown
- 1997-08-25 ES ES97938585T patent/ES2208948T3/es not_active Expired - Lifetime
- 1997-08-25 AU AU40880/97A patent/AU741324B2/en not_active Ceased
- 1997-08-25 PT PT97938585T patent/PT929299E/pt unknown
- 1997-08-25 WO PCT/US1997/014938 patent/WO1998008502A1/en not_active Ceased
- 1997-08-25 IL IL12850097A patent/IL128500A/xx not_active IP Right Cessation
- 1997-08-25 UA UA99021147A patent/UA48245C2/uk unknown
- 1997-08-25 DK DK97938585T patent/DK0929299T3/da active
- 1997-08-25 NZ NZ334031A patent/NZ334031A/xx unknown
- 1997-08-25 CZ CZ99644A patent/CZ64499A3/cs unknown
- 1997-08-25 KR KR1019997001683A patent/KR20000035942A/ko not_active Ceased
- 1997-08-25 EA EA199900241A patent/EA001912B1/ru not_active IP Right Cessation
- 1997-08-25 CN CN97197483A patent/CN1228695A/zh active Pending
- 1997-08-25 YU YU10499A patent/YU10499A/sh unknown
- 1997-08-25 JP JP10511794A patent/JP2000516957A/ja not_active Ceased
- 1997-08-25 AT AT97938585T patent/ATE251457T1/de not_active IP Right Cessation
- 1997-08-25 PL PL97331882A patent/PL331882A1/xx unknown
- 1997-08-25 DE DE69725459T patent/DE69725459T2/de not_active Expired - Fee Related
- 1997-08-25 CA CA002264267A patent/CA2264267A1/en not_active Abandoned
1999
- 1999-02-23 NO NO990849A patent/NO990849D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUP9902901A2 (hu)	2000-05-28
EP0929299A4 (en)	2000-12-20
NO990849L (no)	1999-02-23
NO990849D0 (no)	1999-02-23
ATE251457T1 (de)	2003-10-15
CN1228695A (zh)	1999-09-15
DE69725459D1 (de)	2003-11-13
AU741324B2 (en)	2001-11-29
PL331882A1 (en)	1999-08-16
TR199900430T2 (xx)	1999-06-21
EP0929299A1 (en)	1999-07-21
CA2264267A1 (en)	1998-03-05
EA001912B1 (ru)	2001-10-22
UA48245C2 (uk)	2002-08-15
IL128500A0 (en)	2000-01-31
EA199900241A1 (ru)	1999-08-26
KR20000035942A (ko)	2000-06-26
YU10499A (sh)	2001-03-07
CZ64499A3 (cs)	1999-05-12
PT929299E (pt)	2004-02-27
HUP9902901A3 (en)	2002-01-28
ES2208948T3 (es)	2004-06-16
AU4088097A (en)	1998-03-19
DE69725459T2 (de)	2004-08-12
EP0929299B1 (en)	2003-10-08
JP2000516957A (ja)	2000-12-19
DK0929299T3 (da)	2004-02-16
IL128500A (en)	2003-06-24
NZ334031A (en)	2000-07-28
WO1998008502A1 (en)	1998-03-05

Legal Events

Date	Code	Title	Description
2003-01-07	FB36	Technical and formal requirements: requirement - article 36 of industrial property law
2003-05-06	HJEG	Technical examination (opinion): technical examination (opinion) related to article 229 of industrial property law
2006-03-28	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 8A ANUIDADE.
2011-12-06	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1838 DE 28/03/2006.

Publication	Publication Date	Title
DE59712761D1 (de)	2006-12-14	2- und 2,5-substituierte Phenylketoenole
ID18249A (id)	1998-03-19	Turunan 6,5-hetero-bisiklik tersubstitusi
DK0920429T3 (da)	2003-05-12	Substituerede pyrido- eller pyrimidoholdige, 6,6- eller 6,7-bicykliske derivater
ID29241A (id)	2001-08-16	Turunan-turunan kinolin teranelasi-1,2
NL1007028A1 (nl)	1998-03-16	Stabilisatorcombinatie.
BR9913394B1 (pt)	2010-11-16	material de base lubrificante.
DE69708120D1 (de)	2001-12-13	Laser-absorbierende, lichtbleichbare zusammensetzungen
YU15299A (sh)	2002-06-19	Farmaceutski sastavi
ID28874A (id)	2001-07-12	Inhibitor fosfodiesterase 4 turunan ftalazina.
TR27961A (tr)	1995-11-06	Sübstitüe edilmis 1,2,3,4 -tetrahidro-5-nitro-pirimidinler.
NO985335D0 (no)	1998-11-16	2,4-Diaminopyrimidinderivater
BR9711273A (pt)	1999-08-17	1,2,3,4- Tetraidro-2-dibenzofuranaminas substituidas e 2- aminociclohepta b benzofuranos
DE69627702D1 (de)	2003-05-28	Stabilisierte, korrosionsinhibierte feuerhemmende zusammensetzungen und methoden
DE69906149D1 (de)	2003-04-24	4,5-azolo-oxindole
NO983802L (no)	1998-08-19	Benzothiofener, formuleringer inneholdende samme og fremgangsmåter
BR9916537B1 (pt)	2010-11-16	composição de fragráncia, e, produto.
EP1156040A4 (en)	2002-03-20	2,4-dioxo-5-ARYLIDENIMIDO-1,3-pyrimidines
DE59709923D1 (de)	2003-05-28	2- und 2,5-substituierte phenylketoenole
TR199700219A3 (tr)	1997-10-21	1,25-Dihidroksi-16, 22, 23-Trisdihidro-kolkalsiferol türevleri.
DE69915055D1 (de)	2004-04-01	Antitumorale 1,5-diazaanthraquinone
BR9708948A (pt)	1999-08-03	1,3 - Benzodioxois substituídos
DE69908923D1 (de)	2003-07-24	1,3,4-thiadiazolylazofarbstoffe-enthaltende tintenzusammensetzungen
BR9711721A (pt)	1999-08-24	Paraherquamidas e marcfortinas de 24,25-epoxi e 25-metileno
DZ2644A1 (fr)	2003-03-15	Triazolo-Ä3,4-aÜ-pyridazine substituées en 1,2,4.
IT245391Y1 (it)	2002-03-20	Inferriata scorrevole.