BR9711805A - Compostos e métodos para providenciar preparações farmacologicamente ativas e uso dos mesmos - Google Patents

Compostos e métodos para providenciar preparações farmacologicamente ativas e uso dos mesmos

Info

Publication number
BR9711805A
BR9711805A BR9711805-2A BR9711805A BR9711805A BR 9711805 A BR9711805 A BR 9711805A BR 9711805 A BR9711805 A BR 9711805A BR 9711805 A BR9711805 A BR 9711805A
Authority
BR
Brazil
Prior art keywords
compounds
pharmacologically active
methods
active preparations
relates
Prior art date
Application number
BR9711805-2A
Other languages
English (en)
Inventor
Sean Kerwin
Laurence H Hurley
Mark R Deluca
Bob M Moore Iii
Gregory R Mundy
Original Assignee
Regents The Univesity Of Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regents The Univesity Of Texas filed Critical Regents The Univesity Of Texas
Publication of BR9711805A publication Critical patent/BR9711805A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Quinoline Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

Patente de Invenção: "COMPOSTOS E MéTODOS PARA PROVIDENCIAR PREPARAçõES FARMACOLOGICAMENTE ATIVAS E USO DOS MESMOS". A presente invenção refere-se a compostos farmacologicamente ativos, que são capazes de se ligar aos receptores de hormónio nuclear e que são úteis para a estimulação da proliferação de osteoblasto e, finalmente, crescimento ósseo. Esta invenção também se refere ao uso de tais compostos para o tratamento ou prevenção de doenças e/ou distúrbios associados com famílias de receptor de hormónio nuclear.
BR9711805-2A 1996-06-20 1997-06-20 Compostos e métodos para providenciar preparações farmacologicamente ativas e uso dos mesmos BR9711805A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1608896P 1996-06-20 1996-06-20
PCT/US1997/010643 WO1997048694A1 (en) 1996-06-20 1997-06-20 Compounds and methods for providing pharmacologically active preparations and uses thereof

Publications (1)

Publication Number Publication Date
BR9711805A true BR9711805A (pt) 2002-01-15

Family

ID=21775328

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9711805-2A BR9711805A (pt) 1996-06-20 1997-06-20 Compostos e métodos para providenciar preparações farmacologicamente ativas e uso dos mesmos

Country Status (13)

Country Link
US (1) US6720344B2 (pt)
EP (1) EP0912549A4 (pt)
JP (1) JP2000514048A (pt)
KR (1) KR20000022040A (pt)
CN (1) CN1226245A (pt)
AU (1) AU727708B2 (pt)
BR (1) BR9711805A (pt)
CA (1) CA2258822A1 (pt)
HU (1) HUP9904567A3 (pt)
IL (1) IL127559A0 (pt)
NO (1) NO985975L (pt)
PL (1) PL330814A1 (pt)
WO (1) WO1997048694A1 (pt)

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EP0912549A4 (en) 2002-01-02
PL330814A1 (en) 1999-06-07
NO985975D0 (no) 1998-12-18
IL127559A0 (en) 1999-10-28
EP0912549A1 (en) 1999-05-06
US20030119791A1 (en) 2003-06-26
US6720344B2 (en) 2004-04-13
JP2000514048A (ja) 2000-10-24
AU3791797A (en) 1998-01-07
HUP9904567A2 (hu) 2000-05-28
WO1997048694A1 (en) 1997-12-24
CN1226245A (zh) 1999-08-18
AU727708B2 (en) 2000-12-21
HUP9904567A3 (en) 2001-10-29
KR20000022040A (ko) 2000-04-25
NO985975L (no) 1999-02-18
CA2258822A1 (en) 1997-12-24

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