BR9712824A - Composição oftálmica de fator neurotrófico, agente de tratamento de desordem funcional do nervo ótico e método para tratamento de desordem funcional do nervo ótico - Google Patents
Composição oftálmica de fator neurotrófico, agente de tratamento de desordem funcional do nervo ótico e método para tratamento de desordem funcional do nervo óticoInfo
- Publication number
- BR9712824A BR9712824A BR9712824-4A BR9712824A BR9712824A BR 9712824 A BR9712824 A BR 9712824A BR 9712824 A BR9712824 A BR 9712824A BR 9712824 A BR9712824 A BR 9712824A
- Authority
- BR
- Brazil
- Prior art keywords
- optic nerve
- nerve disorder
- functional optic
- ophthalmic composition
- treatment agent
- Prior art date
Links
- 239000003795 chemical substances by application Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 208000020911 optic nerve disease Diseases 0.000 title abstract 3
- 108010025020 Nerve Growth Factor Proteins 0.000 title 1
- 102000007072 Nerve Growth Factors Human genes 0.000 title 1
- 239000003900 neurotrophic factor Substances 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 208000035475 disorder Diseases 0.000 abstract 3
- 239000003076 neurotropic agent Substances 0.000 abstract 3
- 210000001328 optic nerve Anatomy 0.000 abstract 3
- 208000010412 Glaucoma Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Patente de Invenção:<B>"COMPOSIçãO OFTáLMICA DE FATOR NEUROTRóFICO, AGENTE DE TRATAMENTO DE DESORDEM FUNCIONAL DO NERVO óTICO E MéTODO PARA TRATAMENTO DE DESORDEM FUNCIONAL DO NERVO óTICO"<D>. De acordo com a presente invenção, são fornecidos uma composição oftálmica que compreende um fator neurotrópico, uma agente de tratamento de desordem funcional do nervo ótico que compreende um fator neurotrópico, e um método para tratamento de uma desordem funcional do nervo ótico, que compreende administrar uma quantidade efetiva de um fator neurotrópico, particularmente um agente de tratamento de glaucoma e um método para tratamento do mesmo.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24317996 | 1996-09-13 | ||
| PCT/JP1997/003241 WO1998010785A1 (en) | 1996-09-13 | 1997-09-12 | Ophthalmic compositions of neurotrophic factors, remedies for optic nerve function disorders and method for treating optic nerve function disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9712824A true BR9712824A (pt) | 1999-12-21 |
Family
ID=17100001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9712824-4A BR9712824A (pt) | 1996-09-13 | 1997-09-12 | Composição oftálmica de fator neurotrófico, agente de tratamento de desordem funcional do nervo ótico e método para tratamento de desordem funcional do nervo ótico |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6261545B1 (pt) |
| EP (1) | EP0958831A4 (pt) |
| KR (1) | KR100514277B1 (pt) |
| CN (1) | CN1233963A (pt) |
| AU (1) | AU743308B2 (pt) |
| BR (1) | BR9712824A (pt) |
| CA (1) | CA2265743A1 (pt) |
| IL (1) | IL128941A (pt) |
| WO (1) | WO1998010785A1 (pt) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000024415A2 (en) * | 1998-10-28 | 2000-05-04 | Cornell Research Foundation, Inc. | Methods for regulating angiogenesis and vascular integrity using trk receptor ligands |
| TWI246421B (en) * | 1998-12-03 | 2006-01-01 | Alcon Mfg Ltd | Use of neurotrophic factor stimulators for the treatment of ophthalmic neurodegenerative diseases |
| IT1305294B1 (it) | 1999-01-29 | 2001-05-04 | Alessandro Lambiase | Uso del nerve growth factor nella terapia di patologie a carico deitessuti intraoculari. |
| AU5109400A (en) * | 1999-06-14 | 2001-01-02 | Advanced Medicine Research Institute | Therapeutic compositions for ophthalmic use and therapeutic compositions for brain central lesions |
| KR100693263B1 (ko) * | 1999-07-22 | 2007-03-13 | 아벤티스 파마슈티칼스 인크. | 다중 투여형 에리트로포이에틴 제형 |
| AU2002313716A1 (en) * | 2001-07-31 | 2003-02-17 | University Of Medicine And Dentistry Of New Jersey | Method of utilizing neurotrophins to manipulate reproductive capacity |
| US20030203032A1 (en) | 2002-04-25 | 2003-10-30 | Schultz Clyde L. | Growth factor delivery system for the healing of wounds and the prevention of inflammation and disease |
| JP2005529122A (ja) * | 2002-04-25 | 2005-09-29 | ラピッドヒール インコーポレイティッド | 創傷治癒のための増殖因子送達システムならびに炎症および疾患の予防方法 |
| PL1606409T3 (pl) | 2003-03-19 | 2011-02-28 | Biogen Ma Inc | Białko wiążące receptor Nogo |
| US20050255144A1 (en) * | 2003-04-09 | 2005-11-17 | Directcontact Llc | Methods and articles for the delivery of medicaments to the eye for the treatment of posterior segment diseases |
| US9216106B2 (en) | 2003-04-09 | 2015-12-22 | Directcontact Llc | Device and method for the delivery of drugs for the treatment of posterior segment disease |
| US20050074497A1 (en) * | 2003-04-09 | 2005-04-07 | Schultz Clyde L. | Hydrogels used to deliver medicaments to the eye for the treatment of posterior segment diseases |
| US20050058730A1 (en) * | 2003-09-15 | 2005-03-17 | Xushan Wan | Compositions and methods for preventing or treating eyestrain |
| WO2005027969A1 (ja) * | 2003-09-24 | 2005-03-31 | Santen Pharmaceutical Co., Ltd. | 視神経障害を伴う眼疾患の治療剤 |
| MXPA03011987A (es) * | 2003-12-19 | 2005-06-23 | Osio Sancho Alberto | Metodo para el tratamiento de la presbicia induciendo cambios en el poder y fisiologia corneal. |
| PT1776136E (pt) | 2004-06-24 | 2012-12-05 | Biogen Idec Inc | Tratamento de estados que envolvem desmielinização |
| WO2006040839A1 (ja) * | 2004-10-15 | 2006-04-20 | Advanced Medicine Research Institute | 眼疾患処置用点眼剤及びキット |
| SI1904104T1 (sl) | 2005-07-08 | 2013-12-31 | Biogen Idec Ma Inc. | Protitelesa SP35 in njihova uporaba |
| WO2007011880A2 (en) * | 2005-07-18 | 2007-01-25 | Minu, L.L.C. | Enhanced ocular neuroprotection/neurostimulation |
| US20070014760A1 (en) * | 2005-07-18 | 2007-01-18 | Peyman Gholam A | Enhanced recovery following ocular surgery |
| ITRM20050447A1 (it) * | 2005-08-19 | 2007-02-20 | Anabasis S R L | Uso del nerve growth factor in collirio nella terapia di patologie del sistema nervoso centrale, quali la malattia di alzheimer e il morbo di parkinson. |
| EP1993567A4 (en) * | 2005-10-27 | 2011-01-26 | Lawrence Richard Bernstein | PER OS ADMINISTRABLE GALLIUM PREPARATIONS AND METHODS OF USE |
| US20070259021A1 (en) * | 2006-05-01 | 2007-11-08 | Friedlaender Mitchell H | Compositions, Methods, and Kits for Treating Dry Eye |
| CA2701189C (en) * | 2007-10-11 | 2017-05-16 | Biogen Idec Ma Inc. | Methods for treating pressure induced optic neuropathy, preventing neuronal degeneration and promoting neuronal cell survival via administration of lingo-1 antagonists and trkb agonists |
| US20090156587A1 (en) * | 2007-12-12 | 2009-06-18 | Ravi Nallakrishnan | Eye Medication Formulation with Antibacterial Agent |
| EP2315779A2 (en) | 2008-07-09 | 2011-05-04 | Biogen Idec MA Inc. | Compositions comprising antibodies to lingo or fragments thereof |
| IT1396607B1 (it) * | 2009-11-16 | 2012-12-14 | Hmfra Hungary Ltd Liability Company | Preparazioni oftalmiche a base di bdnf (brain-derived neurotrophic factor) e loro uso. |
| ES2545701T3 (es) * | 2011-12-19 | 2015-09-15 | Wacker Chemie Ag | Nuevos mutantes de proNGF y usos de los mismos en la producción de beta-NGF |
| US9796780B2 (en) | 2012-05-14 | 2017-10-24 | Biogen Ma Inc. | LINGO-2 antagonists for treatment of conditions involving motor neurons |
| MX364260B (es) | 2012-08-10 | 2019-04-17 | Osio Corp D/B/A Yolia Health | Uso de lentes de contacto en el tratamiento de una afección oftalmológica. |
| JP6700180B2 (ja) | 2013-10-28 | 2020-05-27 | アイカーン スクール オブ メディスン アット マウント サイナイIcahn School of Medicine at Mt. Sinai | 神経興奮性および運動行動を調節するための組成物および方法 |
| CN103656621A (zh) * | 2013-12-02 | 2014-03-26 | 黄丽娜 | 一种新型鼠神经生长因子玻璃体腔注射给药系统及其应用 |
| WO2016112270A1 (en) | 2015-01-08 | 2016-07-14 | Biogen Ma Inc. | Lingo-1 antagonists and uses for treatment of demyelinating disorders |
| EP3491104A1 (en) | 2016-07-28 | 2019-06-05 | Shell Internationale Research Maatschappij B.V. | Production of aromatics-rich higher hydrocarbons from solid biomass |
| IT201700066486A1 (it) * | 2017-06-15 | 2018-12-15 | Azienda Ospedaliero Univ Policlinico S Orsola Malpighi Bologn A | Siero sanguigno per uso nel trattamento di patologie neurodegenerative oftalmologiche |
| US12226452B2 (en) * | 2020-03-04 | 2025-02-18 | The Schepens Eye Research Institute, Inc. | Polyhedrin-based slow release growth factor system for neuroprotection of retinal ganglion cell neurons |
| CN111705069A (zh) * | 2020-06-19 | 2020-09-25 | 武汉纽福斯生物科技有限公司 | 一种多神经营养因子联合表达载体及其应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57203440A (en) * | 1981-06-11 | 1982-12-13 | Nihon Contact Lens Seizou Kk | Treating tool |
| CA1295941C (en) * | 1985-08-16 | 1992-02-18 | Rajan Bawa | Sustained-release formulation comprising a hydrophobic polymer system |
| AU615637B2 (en) * | 1986-10-17 | 1991-10-10 | Surmodics, Inc. | Improvement of the biocompatibility of solid surfaces |
| US5260059A (en) * | 1989-04-14 | 1993-11-09 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University | Treatment of open-angle glaucoma by modulation matrix metalloproteinases and their inhibitor |
| US5667968A (en) | 1989-08-30 | 1997-09-16 | Regeneron Pharmaceuticals, Inc. | Prevention of retinal injury and degeneration by specific factors |
| EP0443809A3 (en) | 1990-02-20 | 1992-04-15 | Ioptex Research Inc. | Coated intraocular lens and coatings therefor |
| US5270051A (en) | 1991-10-15 | 1993-12-14 | Harris Donald H | Enzyme-orthokeratology |
| DE69328730T2 (de) * | 1992-02-14 | 2000-09-28 | Regeneron Pharmaceuticals, Inc. | Vorbeugung von verletzungen und degenerationen von photorezeptoren durch neurotrophische faktoren |
| EP0644937A4 (en) * | 1992-06-12 | 1995-05-03 | Regeneron Pharmaceuticals, Inc. | Therapeutic and diagnostic methods based on neurotrophin-4 expression. |
| US5349056A (en) * | 1992-10-09 | 1994-09-20 | Regeneron Pharmaceuticals | Modified ciliary neurotrophic factors |
| EP0753013A1 (en) * | 1994-03-29 | 1997-01-15 | Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V. | Neurotrophin-6: a new member of the neurotrophin family |
| US5898066A (en) * | 1994-08-26 | 1999-04-27 | Children's Medical Center Corporation | Trophic factors for central nervous system regeneration |
| US5641750A (en) * | 1995-11-29 | 1997-06-24 | Amgen Inc. | Methods for treating photoreceptors using glial cell line-derived neurotrophic factor (GDNF) protein product |
| US5641749A (en) * | 1995-11-29 | 1997-06-24 | Amgen Inc. | Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product |
| US5904144A (en) * | 1996-03-22 | 1999-05-18 | Cytotherapeutics, Inc. | Method for treating ophthalmic diseases |
| JPH10212241A (ja) * | 1996-05-27 | 1998-08-11 | Sumitomo Pharmaceut Co Ltd | Bdnfを安定に含有する製剤 |
-
1997
- 1997-09-12 WO PCT/JP1997/003241 patent/WO1998010785A1/ja not_active Ceased
- 1997-09-12 BR BR9712824-4A patent/BR9712824A/pt not_active Application Discontinuation
- 1997-09-12 US US09/254,587 patent/US6261545B1/en not_active Expired - Fee Related
- 1997-09-12 CA CA002265743A patent/CA2265743A1/en not_active Abandoned
- 1997-09-12 EP EP97940376A patent/EP0958831A4/en not_active Withdrawn
- 1997-09-12 KR KR10-1999-7002139A patent/KR100514277B1/ko not_active Expired - Fee Related
- 1997-09-12 AU AU42209/97A patent/AU743308B2/en not_active Ceased
- 1997-09-12 CN CN97198930A patent/CN1233963A/zh active Pending
- 1997-09-12 IL IL128941A patent/IL128941A/en not_active IP Right Cessation
-
2001
- 2001-05-23 US US09/863,847 patent/US20010023245A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0958831A4 (en) | 2004-04-07 |
| KR20000036116A (ko) | 2000-06-26 |
| EP0958831A1 (en) | 1999-11-24 |
| US6261545B1 (en) | 2001-07-17 |
| CA2265743A1 (en) | 1998-03-19 |
| US20010023245A1 (en) | 2001-09-20 |
| AU4220997A (en) | 1998-04-02 |
| AU743308B2 (en) | 2002-01-24 |
| IL128941A (en) | 2007-05-15 |
| CN1233963A (zh) | 1999-11-03 |
| IL128941A0 (en) | 2000-02-17 |
| WO1998010785A1 (en) | 1998-03-19 |
| KR100514277B1 (ko) | 2005-09-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: O DEPOSITANTE DEIXOU DE APRESENTAR MANIFESTACAO SOBRE O PARECER NEGATIVO, ASSIM, DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. |