BR9808221A - Método de tratamento de tumor. - Google Patents

Método de tratamento de tumor.

Info

Publication number
BR9808221A
BR9808221A BR9808221-3A BR9808221A BR9808221A BR 9808221 A BR9808221 A BR 9808221A BR 9808221 A BR9808221 A BR 9808221A BR 9808221 A BR9808221 A BR 9808221A
Authority
BR
Brazil
Prior art keywords
mammal
administering
effective amount
treatment method
tumor treatment
Prior art date
Application number
BR9808221-3A
Other languages
English (en)
Inventor
Daniel L Dexter
Paul E Juniewicz
James B Rake
Daniel D Von Hoff
Original Assignee
Sanofi Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Winthrop Inc filed Critical Sanofi Winthrop Inc
Publication of BR9808221A publication Critical patent/BR9808221A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Patente de Invenção: <B> "MéTODO DE TRATAMENTO DE TUMOR". <D> De acordo com a presente invenção é provido um método de tratamento de um mamífero que tem um tumor sólido, o método compreende: a) administrar ao mamífero uma quantidade eficaz de 1,4 dióxido de 3-amino-1,2,4-benzotriazina; b) administrar ao manífero uma quantidade eficaz de paclitaxel; e c) administrar ao mamífero uma quantidade eficaz de complexo de platina. O método provê eficácia sinergética inesperada. A invenção ainda provê um kit para tratamento de um tumor em mamíferos que compreende 1,4 dióxido de 3-amino-1,2,4-benzotriazina, paclitaxel e um complexo de platina.
BR9808221-3A 1997-03-07 1998-02-17 Método de tratamento de tumor. BR9808221A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81476997A 1997-03-07 1997-03-07
PCT/US1998/003292 WO1998039009A1 (en) 1997-03-07 1998-02-17 Method of treating a tumor

Publications (1)

Publication Number Publication Date
BR9808221A true BR9808221A (pt) 2000-05-16

Family

ID=25215967

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9808221-3A BR9808221A (pt) 1997-03-07 1998-02-17 Método de tratamento de tumor.

Country Status (15)

Country Link
US (2) US6063780A (pt)
EP (1) EP1014990B1 (pt)
JP (1) JP2001513110A (pt)
AT (1) ATE338553T1 (pt)
AU (1) AU6178198A (pt)
BR (1) BR9808221A (pt)
CA (1) CA2281807C (pt)
DE (1) DE69835824T2 (pt)
DK (1) DK1014990T3 (pt)
ES (1) ES2268764T3 (pt)
HR (1) HRP980095A2 (pt)
NO (1) NO324974B1 (pt)
PT (1) PT1014990E (pt)
WO (1) WO1998039009A1 (pt)
ZA (1) ZA981609B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6178198A (en) * 1997-03-07 1998-09-22 Sanofi Pharmaceuticals, Inc. Method of treating a tumor
US6866857B1 (en) 1998-10-14 2005-03-15 Debiopharm S.A. Oxalipatinum preparation packaging
DE19925211B4 (de) * 1999-06-01 2006-01-12 PBS Pharmaceutical Bulk Substances SA Kit zur Herstellung einer Formulierung von Paclitaxel
CA2382389C (fr) * 1999-08-30 2010-06-29 Debiopharm S.A. Preparation pharmaceutique stable d'oxaliplatine pour administration par voie parenterale
US7070796B1 (en) 1999-08-30 2006-07-04 Debiopharm S.A. Pharmaceutically stable oxaliplatinum preparation for parenteral administration
AU2002223013A1 (en) 2000-12-12 2002-06-24 Debiopharm S.A. Pharmaceutical oxaliplatinum preparation for parenteral administration and method for obtaining same
US6476068B1 (en) 2001-12-06 2002-11-05 Pharmacia Italia, S.P.A. Platinum derivative pharmaceutical formulations
AU2003261354A1 (en) * 2002-08-02 2004-02-23 The Regents Of The University Of California New uses for inhibitors of inosine monophosphate dehydrogenase
AU2003239511A1 (en) * 2003-05-20 2004-12-13 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
US7989490B2 (en) * 2004-06-02 2011-08-02 Cordis Corporation Injectable formulations of taxanes for cad treatment
US20060275331A1 (en) * 2004-08-31 2006-12-07 Borek Zaludek Pharmaceutical composition, method of manufacturing and therapeutic use thereof
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
CA2624707A1 (en) * 2005-10-03 2007-04-12 Genetix Pharmaceuticals, Inc. Method for selectively depleting hypoxic cells
US20070212360A1 (en) * 2006-01-17 2007-09-13 Denko Nicholas C Modulation of mitochondrial oxygen consumption for therapeutic purposes
US8026017B2 (en) 2007-03-16 2011-09-27 The United States Of America As Represented By The Secretary Of The Army High voltage methanol fuel cell assembly using proton exchange membranes and base/acid electrolytes
CN102026634B (zh) 2008-04-10 2014-01-22 弗吉尼亚州立邦联大学 诱导肿瘤缺氧以治疗癌症
US9278124B2 (en) 2012-10-16 2016-03-08 Halozyme, Inc. Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods
EP4201403A1 (en) * 2021-12-21 2023-06-28 Som Innovation Biotech, S.L. Compounds tirapazamine and quazinone for use in the treatment of gm2 gangliosidoses

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399363A (en) * 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
US5484612A (en) * 1993-09-22 1996-01-16 The Board Of Trustees Of The Leland Stanford Junior University Method of treating a mammal having a solid tumor susceptible to treatment with cisplatin
AU6178198A (en) * 1997-03-07 1998-09-22 Sanofi Pharmaceuticals, Inc. Method of treating a tumor

Also Published As

Publication number Publication date
EP1014990A1 (en) 2000-07-05
ATE338553T1 (de) 2006-09-15
NO994330L (no) 1999-10-25
DE69835824T2 (de) 2007-03-29
CA2281807C (en) 2007-10-16
ZA981609B (en) 1998-12-08
NO994330D0 (no) 1999-09-06
NO324974B1 (no) 2008-01-14
JP2001513110A (ja) 2001-08-28
EP1014990A4 (en) 2004-03-24
PT1014990E (pt) 2006-11-30
DK1014990T3 (da) 2006-12-11
US6063780A (en) 2000-05-16
AU6178198A (en) 1998-09-22
WO1998039009A1 (en) 1998-09-11
ES2268764T3 (es) 2007-03-16
US6319923B1 (en) 2001-11-20
EP1014990B1 (en) 2006-09-06
CA2281807A1 (en) 1998-09-11
DE69835824D1 (de) 2006-10-19
HRP980095A2 (en) 1998-12-31

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Legal Events

Date Code Title Description
TC Change of name
B25A Requested transfer of rights approved

Owner name: SANOFI-AVENTIS U.S. LLC (US)

Free format text: TRANSFERIDO DE: SANOFI-SYNTHELABO INC.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO, UMA VEZ QUE SE OPOE AO DISPOSTO NO ART. 10 ( VIII ) DA LPI

B15G Petition not considered as such [chapter 15.7 patent gazette]

Free format text: DESCONHECIDA A PETICAO DE ALTERACAO DE SEDE, NO 020070160149/RJ DE 13/11/2007, POR AUSENCIA DE FUNDAMENTACAO LEGAL, UMA VEZ QUE O PEDIDO FOI INDEFERIDO NA RPI 1924 DE 20/11/2007.