BR9900623A - Parasiticidas derivados de pirazóis. - Google Patents
Parasiticidas derivados de pirazóis.Info
- Publication number
- BR9900623A BR9900623A BR9900623-5A BR9900623A BR9900623A BR 9900623 A BR9900623 A BR 9900623A BR 9900623 A BR9900623 A BR 9900623A BR 9900623 A BR9900623 A BR 9900623A
- Authority
- BR
- Brazil
- Prior art keywords
- halo
- hydrogen
- parasiticides
- pyrazole
- derived
- Prior art date
Links
- WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical compound C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 title 1
- 230000000590 parasiticidal effect Effects 0.000 title 1
- 239000002297 parasiticide Substances 0.000 title 1
- 125000005843 halogen group Chemical group 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- -1 2,4,6-trisubstituted phenyl Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
- 239000003096 antiparasitic agent Substances 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Public Health (AREA)
- Agronomy & Crop Science (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pretreatment Of Seeds And Plants (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Lubricants (AREA)
- Steroid Compounds (AREA)
Abstract
Patente de Invenção:<B>" PARASITICIDAS DERIVADOS DE PIRAZóIS"<D>. Os compostos da fórmula (I): ou seus sais farmaceuticamente veterinariamente ou agricolamente aceitáveis, ou solvatos de cada uma das entidades farmaceuticamente, veterinariamente ou agricolamente aceitáveis, em que R^ 1^ é uma fenila 2,4,6-trissubstituída ou piridin-2-ila 3,5-dissubstituída; R^ 3^ é hidrogênio; alquila de C2 a C5 substituída com um ou mais grupos halo e com hidroxila; alcanoíla de C2 a C5 substituída com um ou mais halo; alquenila de C2 a C6 opcionalmente substituída com um ou mais halo; halo; amino ou CONH2; R^ 5^ é hidrogênio, amino ou halo; R^ 2^ e R^ 4^são cada um selecionados independentemente de hidrogênio, flúor, cloro e bromo; R^ 6^ e R^ 8^ são hidrogênio; e R^ 7^ hidrogênio ou alquila de C1a C4, opcionalmente substituída com um ou mais halo; são agentes parasiticidas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9801851.8A GB9801851D0 (en) | 1998-01-29 | 1998-01-29 | Parasiticidal agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9900623A true BR9900623A (pt) | 2000-05-09 |
Family
ID=10826064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9900623-5A BR9900623A (pt) | 1998-01-29 | 1999-01-28 | Parasiticidas derivados de pirazóis. |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US6090394A (pt) |
| EP (1) | EP0933363B1 (pt) |
| JP (1) | JPH11279155A (pt) |
| AT (1) | ATE248151T1 (pt) |
| BR (1) | BR9900623A (pt) |
| CA (1) | CA2260412C (pt) |
| DE (1) | DE69910633T2 (pt) |
| DK (1) | DK0933363T3 (pt) |
| ES (1) | ES2205710T3 (pt) |
| GB (1) | GB9801851D0 (pt) |
| PT (1) | PT933363E (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9916052D0 (en) * | 1999-07-08 | 1999-09-08 | Pfizer Ltd | Anthelmintic compositions |
| DE10300124A1 (de) * | 2003-01-07 | 2004-07-15 | Bayer Ag | Verfahren zur Herstellung von Arylalkinen |
| WO2005023773A1 (en) * | 2003-09-04 | 2005-03-17 | Pfizer Limited | Process for the preparation of substituted aryl pyrazoles |
| GB0329314D0 (en) * | 2003-12-18 | 2004-01-21 | Pfizer Ltd | Substituted arylpyrazoles |
| US7514464B2 (en) * | 2003-12-18 | 2009-04-07 | Pfizer Limited | Substituted arylpyrazoles |
| US20060069310A1 (en) * | 2004-09-30 | 2006-03-30 | Couvillon Lucien A Jr | Programmable brake control system for use in a medical device |
| US20080146643A1 (en) * | 2005-06-15 | 2008-06-19 | Pfizer Limited | Combination |
| US7645786B2 (en) | 2005-06-15 | 2010-01-12 | Pfizer Inc. | Substituted arylpyrazoles |
| US20080176865A1 (en) * | 2005-06-15 | 2008-07-24 | Pfizer Limited | Substituted arylpyrazoles |
| DE602006012042D1 (de) | 2005-06-15 | 2010-03-18 | Pfizer Ltd | Substituierte arylpyrazole zur verwendung gegen parasiten |
| DE102006061537A1 (de) | 2006-12-27 | 2008-07-03 | Bayer Healthcare Ag | Mittel zur Bekämpfung von Parasiten an Tieren |
| DE102006061538A1 (de) * | 2006-12-27 | 2008-07-03 | Bayer Healthcare Ag | Kombinationsprodukt zur Bekämpfung von Parasiten an Tieren |
| KR20110098012A (ko) * | 2007-02-09 | 2011-08-31 | 화이자 리미티드 | 구충제 |
| BR112014006940A2 (pt) | 2011-09-23 | 2017-04-04 | Bayer Ip Gmbh | uso de derivados de ácido 1-fenilpirazol-3-carboxílico 4-substituído como agentes contra estresse abiótico em plantas |
| JO3626B1 (ar) | 2012-02-23 | 2020-08-27 | Merial Inc | تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها |
| CN111116478B (zh) * | 2019-12-18 | 2021-10-26 | 浙江金伯士药业有限公司 | 一种兽用抗生素维吉霉素中间体的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8531485D0 (en) * | 1985-12-20 | 1986-02-05 | May & Baker Ltd | Compositions of matter |
| DE3712934A1 (de) * | 1987-04-16 | 1988-11-03 | Bayer Ag | Substituierte 1-arylpyrazole |
| GB9601128D0 (en) * | 1995-08-11 | 1996-03-20 | Pfizer Ltd | Parasiticidal compounds |
| GB9625045D0 (en) * | 1996-11-30 | 1997-01-22 | Pfizer Ltd | Parasiticidal compounds |
| TW524667B (en) * | 1996-12-05 | 2003-03-21 | Pfizer | Parasiticidal pyrazoles |
-
1998
- 1998-01-29 GB GBGB9801851.8A patent/GB9801851D0/en not_active Ceased
-
1999
- 1999-01-19 JP JP11010416A patent/JPH11279155A/ja active Pending
- 1999-01-19 DE DE69910633T patent/DE69910633T2/de not_active Expired - Lifetime
- 1999-01-19 ES ES99300330T patent/ES2205710T3/es not_active Expired - Lifetime
- 1999-01-19 AT AT99300330T patent/ATE248151T1/de not_active IP Right Cessation
- 1999-01-19 PT PT99300330T patent/PT933363E/pt unknown
- 1999-01-19 DK DK99300330T patent/DK0933363T3/da active
- 1999-01-19 EP EP99300330A patent/EP0933363B1/en not_active Expired - Lifetime
- 1999-01-22 US US09/235,957 patent/US6090394A/en not_active Expired - Lifetime
- 1999-01-27 CA CA002260412A patent/CA2260412C/en not_active Expired - Fee Related
- 1999-01-28 BR BR9900623-5A patent/BR9900623A/pt not_active IP Right Cessation
- 1999-07-01 US US09/346,161 patent/US6019986A/en not_active Expired - Lifetime
-
2002
- 2002-04-29 US US10/134,887 patent/US20020173662A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE248151T1 (de) | 2003-09-15 |
| CA2260412C (en) | 2002-12-10 |
| PT933363E (pt) | 2004-01-30 |
| EP0933363A1 (en) | 1999-08-04 |
| EP0933363B1 (en) | 2003-08-27 |
| DE69910633T2 (de) | 2004-07-29 |
| JPH11279155A (ja) | 1999-10-12 |
| ES2205710T3 (es) | 2004-05-01 |
| US6019986A (en) | 2000-02-01 |
| CA2260412A1 (en) | 1999-07-29 |
| GB9801851D0 (en) | 1998-03-25 |
| US6090394A (en) | 2000-07-18 |
| DK0933363T3 (da) | 2003-09-29 |
| US20020173662A1 (en) | 2002-11-21 |
| DE69910633D1 (de) | 2003-10-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AO NAO RECOLHIMENTO DA(S) 9A E 10A ANUIDADE(S). |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 1986 DE 27/03/2009. |