BR9907967A - Composto de polipeptideo, processo para sua preparação, composição farmacêutica compreendendo dito composto, e seu uso. - Google Patents

Composto de polipeptideo, processo para sua preparação, composição farmacêutica compreendendo dito composto, e seu uso.

Info

Publication number
BR9907967A
BR9907967A BR9907967-4A BR9907967A BR9907967A BR 9907967 A BR9907967 A BR 9907967A BR 9907967 A BR9907967 A BR 9907967A BR 9907967 A BR9907967 A BR 9907967A
Authority
BR
Brazil
Prior art keywords
compound
preparation
pharmaceutical composition
polypeptide
pneumocystis carinii
Prior art date
Application number
BR9907967-4A
Other languages
English (en)
Inventor
Hidenori Ohki
Kenji Murano
Takashi Tojo
Nobuyuki Shiraishi
Takahiro Matsuya
Hiroshi Matsuda
Hiroaki Mizuno
David Barrett
Keiji Matsuda
Kohji Kawabata
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPP1728A external-priority patent/AUPP172898A0/en
Priority claimed from AUPP3138A external-priority patent/AUPP313898A0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of BR9907967A publication Critical patent/BR9907967A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"COMPOSTO DE POLIPEPTìDEO, PROCESSO PARA SUA PREPARAçãO, COMPOSIçãO FARMACêUTICA COMPREENDENDO DITO COMPOSTO, E SEU USO". A presente invenção refere-se a novos compostos de polipeptídeo representados pela fórmula geral (I), onde R^ 1^, R^ 2^, R^ 3^e R^ 4^ são conforme definidos na descrição, ou um sal dos mesmos apresentando atividades antimicrobianas (especialmente atividades antifúngicas), atividade inibidora da sintase de <225>-1, 3-glucano, a um processo para sua preparação a uma composição farmacêutica compreendendo o mesmo, e a um método para o tratamento profilático e/ou terapêutico de doenças infecciosas, inclusive infecção por <MU> Pneumocystis carinii <MV> (ex: pneumonia causada por <MU> Pneumocystis carinii <MV>) num ser humano ou animal.
BR9907967-4A 1998-02-09 1999-02-05 Composto de polipeptideo, processo para sua preparação, composição farmacêutica compreendendo dito composto, e seu uso. BR9907967A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPP1728A AUPP172898A0 (en) 1998-02-09 1998-02-09 New compound
AUPP3138A AUPP313898A0 (en) 1998-04-23 1998-04-23 New compound
PCT/JP1999/000538 WO1999040108A1 (en) 1998-02-09 1999-02-05 New compound

Publications (1)

Publication Number Publication Date
BR9907967A true BR9907967A (pt) 2000-10-17

Family

ID=25645713

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9907967-4A BR9907967A (pt) 1998-02-09 1999-02-05 Composto de polipeptideo, processo para sua preparação, composição farmacêutica compreendendo dito composto, e seu uso.

Country Status (13)

Country Link
US (1) US6232290B1 (pt)
EP (1) EP1053247A1 (pt)
JP (2) JP3561917B2 (pt)
KR (1) KR100396737B1 (pt)
CN (1) CN1240713C (pt)
AR (1) AR014554A1 (pt)
BR (1) BR9907967A (pt)
CA (1) CA2320416A1 (pt)
HU (1) HUP0102515A3 (pt)
IL (1) IL137494A0 (pt)
NO (1) NO20003996L (pt)
TR (1) TR200003064T2 (pt)
WO (1) WO1999040108A1 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020002476A (ko) * 1999-03-03 2002-01-09 피터 지. 스트링거 결정질 에키노칸딘 암모늄염의 형성 및 음이온 교환
AUPP999799A0 (en) 1999-04-27 1999-05-20 Fujisawa Pharmaceutical Co., Ltd. New compound
TWI250992B (en) * 2000-02-21 2006-03-11 Astellas Pharma Inc Polypeptide compounds for the prophylactic and/or therapeutic treatment of infectious diseases caused by pathogenic microorganisms
US7208503B2 (en) * 2000-04-21 2007-04-24 Janssen Pharmaceutica N.V. Angiogenesis inhibiting 5-substituted-1,2,4-thiadiazolyl derivatives
US6316475B1 (en) * 2000-11-17 2001-11-13 Abbott Laboratories Aminoalkoxybiphenylcarboxamides as histamine-3 receptor ligands and their therapeutic applications
AUPR362001A0 (en) * 2001-03-08 2001-04-05 Fujisawa Pharmaceutical Co., Ltd. New compound
AUPS044102A0 (en) * 2002-02-11 2002-03-07 Fujisawa Pharmaceutical Co., Ltd. New compound
AU2003903205A0 (en) * 2003-06-23 2003-07-10 Fujisawa Pharmaceutical Co., Ltd. New compound
AU2003903629A0 (en) * 2003-07-14 2003-07-31 Fujisawa Pharmaceutical Co., Ltd. New compound
EP1815206B1 (en) * 2004-10-13 2016-04-06 PTC Therapeutics, Inc. Compounds for nonsense suppression, and methods for their use
JP2008545767A (ja) * 2005-06-08 2008-12-18 ノバルティス アクチエンゲゼルシャフト 多環式オキサジアゾールまたはイソキサゾールおよびｓｉｐ受容体リガンドとしてのそれらの使用
JP2009501721A (ja) * 2005-07-12 2009-01-22 アカディア ファーマシューティカルズ インコーポレイテッド レチノイン酸受容体における活性を伴う化合物
EP1902022A1 (en) * 2005-07-12 2008-03-26 Glaxo Group Limited Piperazine heteroaryl derivates as gpr38 agonists
EP1932833B1 (en) * 2005-10-07 2012-08-01 Kissei Pharmaceutical Co., Ltd. Nitrogenated heterocyclic compound and pharmaceutical composition comprising the same
CN101516387B (zh) * 2006-07-26 2014-06-04 桑多斯股份公司 卡泊芬净制剂
HUE036519T2 (hu) 2007-08-13 2018-07-30 Monsanto Technology Llc Készítmények és eljárások nematódák irtására
CA2704562A1 (en) 2007-10-29 2009-05-07 Astellas Pharma Inc. Polypeptide compound
WO2009113661A1 (ja) 2008-03-14 2009-09-17 アステラス製薬株式会社 環状化合物およびその塩
WO2010081851A1 (en) 2009-01-14 2010-07-22 Genoscience Pharma Piperidin-4-ylpiperazine compounds for the treatment of hcv infection
US20120059038A1 (en) * 2009-05-14 2012-03-08 Astellas Pharma Inc. Polyketide compound
US9353072B2 (en) * 2012-10-31 2016-05-31 Purdue Research Foundation Antimicrobial substituted thiazoles and methods of use
WO2019207413A1 (en) 2018-04-25 2019-10-31 Universidad De La República (Udelar) Cyclic hexapeptides compounds with anti-malarial activity
CN114173772A (zh) * 2019-04-12 2022-03-11 托尼克斯医药控股公司 Cd40-cd154结合的抑制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL98506A (en) 1990-06-18 1996-09-12 Fujisawa Pharmaceutical Co Cyclic peptide antibiotics processes for the preparation thereof and pharmaceutical compositions containing them
US5965525A (en) * 1992-03-19 1999-10-12 Eli Lilly And Company Cyclic peptide antifungal agents
AU681119B2 (en) 1993-05-17 1997-08-21 Fujisawa Pharmaceutical Co., Ltd. New polypeptide compound and a process for preparation thereof
JP2897427B2 (ja) * 1994-10-07 1999-05-31 藤沢薬品工業株式会社 抗微生物活性を有する環状ヘキサペプチド化合物
US5629289A (en) * 1995-07-25 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents

Also Published As

Publication number Publication date
CN1296494A (zh) 2001-05-23
KR100396737B1 (ko) 2003-09-13
CN1240713C (zh) 2006-02-08
AR014554A1 (es) 2001-02-28
US6232290B1 (en) 2001-05-15
NO20003996D0 (no) 2000-08-08
CA2320416A1 (en) 1999-08-12
WO1999040108A1 (en) 1999-08-12
HUP0102515A3 (en) 2001-12-28
JP3561917B2 (ja) 2004-09-08
JP2001522377A (ja) 2001-11-13
EP1053247A1 (en) 2000-11-22
TR200003064T2 (tr) 2001-02-21
HUP0102515A2 (hu) 2001-11-28
NO20003996L (no) 2000-10-09
IL137494A0 (en) 2001-07-24
JP2004067699A (ja) 2004-03-04

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A,9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1990 DE 25/02/2009.