BRPI0415613A - novos compostos de diazaspiroalcanos e seu uso no tratamento de doenças mediadas por ccr8 - Google Patents

novos compostos de diazaspiroalcanos e seu uso no tratamento de doenças mediadas por ccr8

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Publication number
BRPI0415613A
BRPI0415613A BRPI0415613-7A BRPI0415613A BRPI0415613A BR PI0415613 A BRPI0415613 A BR PI0415613A BR PI0415613 A BRPI0415613 A BR PI0415613A BR PI0415613 A BRPI0415613 A BR PI0415613A
Authority
BR
Brazil
Prior art keywords
compounds
ccr8
treatment
mediated diseases
diazaspiroalkane
Prior art date
Application number
BRPI0415613-7A
Other languages
English (en)
Inventor
Blah Hakan
Connolly Stephen
Hazel Dyke Joan
Lisius Annea
Price Stephen
Shamovsky Igor
Van Den Heuvel Marco
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29546627&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0415613(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BRPI0415613A publication Critical patent/BRPI0415613A/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Endocrinology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)

Abstract

"NOVOS COMPOSTOS DE DIAZASPIROALCANOS E SEU USO NO TRATAMENTO DE DOENçAS MEDIADAS POR CCR8". A presente invenção refere-se à provisão de compostos de fórmula geral (I), em que A, B, w, x, y, z, D, E, R¬ 1¬ e n são como definidos no relatório descritivo, a processos para sua preparação, a composições farmacêuticas contendo os mesmos e o uso de tais compostos em procedimentos de terapia.
BRPI0415613-7A 2003-10-23 2004-10-21 novos compostos de diazaspiroalcanos e seu uso no tratamento de doenças mediadas por ccr8 BRPI0415613A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0302811A SE0302811D0 (sv) 2003-10-23 2003-10-23 Novel compounds
PCT/SE2004/001522 WO2005040167A1 (en) 2003-10-23 2004-10-21 Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases

Publications (1)

Publication Number Publication Date
BRPI0415613A true BRPI0415613A (pt) 2006-12-05

Family

ID=29546627

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0415613-7A BRPI0415613A (pt) 2003-10-23 2004-10-21 novos compostos de diazaspiroalcanos e seu uso no tratamento de doenças mediadas por ccr8

Country Status (17)

Country Link
US (1) US20070249648A1 (pt)
EP (1) EP1678178A1 (pt)
JP (1) JP2007509141A (pt)
KR (1) KR20060088557A (pt)
CN (1) CN1898239A (pt)
AR (1) AR046600A1 (pt)
AU (1) AU2004284028B2 (pt)
BR (1) BRPI0415613A (pt)
CA (1) CA2542226A1 (pt)
IL (1) IL174698A0 (pt)
MX (1) MXPA06004300A (pt)
NO (1) NO20062335L (pt)
SE (1) SE0302811D0 (pt)
TW (1) TW200528451A (pt)
UY (1) UY28572A1 (pt)
WO (1) WO2005040167A1 (pt)
ZA (1) ZA200603174B (pt)

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PT2858975T (pt) * 2012-06-08 2019-07-16 Univ Pittsburgh Commonwealth Sys Higher Education Inibidores de fbxo3
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PL2900669T3 (pl) 2012-09-25 2020-01-31 F. Hoffmann-La Roche Ag Pochodne heksahydropirolo[3,4-C]pirolu i związki pokrewne jako inhibitory autotaksyny (ATX) oraz inhibitory produkcji kwasu lizofosfatydowego (LPA) do leczenia np. chorób nerek
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