BR9908083A - polipeptìdeo, molécula de dna, vetor de expressão recombinante, célula hospedeira, processo para detectar infecção de m. tuberculosis em uma amostra biológica, kit diagnóstico, anticorpo monoclonal, e, proteìna de fusão - Google Patents

polipeptìdeo, molécula de dna, vetor de expressão recombinante, célula hospedeira, processo para detectar infecção de m. tuberculosis em uma amostra biológica, kit diagnóstico, anticorpo monoclonal, e, proteìna de fusão

Info

Publication number
BR9908083A
BR9908083A BRPI9908083-4A BR9908083A BR9908083A BR 9908083 A BR9908083 A BR 9908083A BR 9908083 A BR9908083 A BR 9908083A BR 9908083 A BR9908083 A BR 9908083A
Authority
BR
Brazil
Prior art keywords
tuberculosis
polypeptide
host cell
expression vector
dna molecule
Prior art date
Application number
BRPI9908083-4A
Other languages
English (en)
Inventor
Steven G Reed
Yasir A W Skeiky
Davin C Dillon
Antonio Campos-Neto
Raymond Houghton
Thomas S Vedvick
Daniel R Twardzik
Michael J Lodes
Ronald C Hendrickson
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp filed Critical Corixa Corp
Publication of BR9908083A publication Critical patent/BR9908083A/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1289—Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)

Abstract

POLIPEPTìDEO, MOLéCULA DE DNA, VETOR DE EXPRESSãO RECOMBINANTE, CéLULA HOSPEDEIRA, PROCESSO PARA DETECTAR INFECçãO DE M. TUBERCULOSIS EM UMA AMOSTRA BIOLóGICA , KIT DIAGNóSTICO, ANTICORPO MONOCLONAL, E, PROTEìNA DE FUSãO Um polipeptídeo (I) compreendendo uma porção antigênica/imunogênica de um antígeno de M. tuberculosis solúvel ou uma variante o antígeno com apenas substituições e/ou modificações consevadoras é novo.
BRPI9908083-4A 1998-02-18 1999-02-17 polipeptìdeo, molécula de dna, vetor de expressão recombinante, célula hospedeira, processo para detectar infecção de m. tuberculosis em uma amostra biológica, kit diagnóstico, anticorpo monoclonal, e, proteìna de fusão BR9908083A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2475398A 1998-02-18 1998-02-18
US09/072,596 US6458366B1 (en) 1995-09-01 1998-05-05 Compounds and methods for diagnosis of tuberculosis
PCT/US1999/003265 WO1999042118A2 (en) 1998-02-18 1999-02-17 Compounds and methods for diagnosis of tuberculosis

Publications (1)

Publication Number Publication Date
BR9908083A true BR9908083A (pt) 2007-07-17

Family

ID=26698832

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9908083-4A BR9908083A (pt) 1998-02-18 1999-02-17 polipeptìdeo, molécula de dna, vetor de expressão recombinante, célula hospedeira, processo para detectar infecção de m. tuberculosis em uma amostra biológica, kit diagnóstico, anticorpo monoclonal, e, proteìna de fusão

Country Status (8)

Country Link
US (4) US6458366B1 (pt)
EP (1) EP1091749A1 (pt)
JP (1) JP2002530050A (pt)
CN (1) CN1312723A (pt)
AU (1) AU2681999A (pt)
BR (1) BR9908083A (pt)
CA (1) CA2322617A1 (pt)
WO (1) WO1999042118A2 (pt)

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US6949246B2 (en) 2005-09-27
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AU2681999A (en) 1999-09-06
US20070141087A1 (en) 2007-06-21
US7906277B2 (en) 2011-03-15
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US6458366B1 (en) 2002-10-01
CA2322617A1 (en) 1999-08-26
US20050181419A1 (en) 2005-08-18
CN1312723A (zh) 2001-09-12
US20030135026A1 (en) 2003-07-17
EP1091749A1 (en) 2001-04-18
US7122196B2 (en) 2006-10-17

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