BR9911068A - Terapia combinada para tratamento de distúrbios bipolares - Google Patents
Terapia combinada para tratamento de distúrbios bipolaresInfo
- Publication number
- BR9911068A BR9911068A BR9911068-7A BR9911068A BR9911068A BR 9911068 A BR9911068 A BR 9911068A BR 9911068 A BR9911068 A BR 9911068A BR 9911068 A BR9911068 A BR 9911068A
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- bipolar disorders
- combination therapy
- bipolar
- depression
- Prior art date
Links
- 208000020925 Bipolar disease Diseases 0.000 title abstract 4
- 238000002648 combination therapy Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 2
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 239000003693 atypical antipsychotic agent Substances 0.000 abstract 1
- 229940127236 atypical antipsychotics Drugs 0.000 abstract 1
- 208000028683 bipolar I disease Diseases 0.000 abstract 1
- 208000025307 bipolar depression Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 201000003104 endogenous depression Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 208000024714 major depressive disease Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000009103 reabsorption Effects 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Electrotherapy Devices (AREA)
Abstract
Patente de Invenção: <B>"TERAPIA COMBINADA PARA TRATAMENTO DE DISTúRBIOS BIPOLARES"<D>. A presente invenção propicia métodos e composições para o tratamento de Distúrbio Bipolar, Depressão Bipolar ou Depressão Unipolar, todas essas com ou sem características psicóticas. Este método emprega um composto dotado de atividade como um antipsicótico atípico e um inibidor da reabsorção de serotonina.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8712698P | 1998-05-29 | 1998-05-29 | |
| PCT/US1999/011314 WO1999062522A1 (en) | 1998-05-29 | 1999-05-21 | Combination therapy for treatment of bipolar disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9911068A true BR9911068A (pt) | 2001-02-06 |
Family
ID=22203275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9911068-7A BR9911068A (pt) | 1998-05-29 | 1999-05-21 | Terapia combinada para tratamento de distúrbios bipolares |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0966967A3 (pt) |
| JP (1) | JP2002516864A (pt) |
| KR (1) | KR20010043731A (pt) |
| CN (1) | CN1302207A (pt) |
| AU (1) | AU756468B2 (pt) |
| BR (1) | BR9911068A (pt) |
| CA (1) | CA2332408A1 (pt) |
| CZ (1) | CZ20004280A3 (pt) |
| EA (1) | EA003611B1 (pt) |
| HR (1) | HRP20000798A2 (pt) |
| HU (1) | HUP0102511A2 (pt) |
| IL (1) | IL139591A0 (pt) |
| NO (1) | NO20005884L (pt) |
| NZ (1) | NZ507981A (pt) |
| PL (1) | PL344304A1 (pt) |
| SK (1) | SK17492000A3 (pt) |
| TR (1) | TR200003525T2 (pt) |
| WO (1) | WO1999062522A1 (pt) |
| ZA (1) | ZA200006817B (pt) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6960577B2 (en) | 1998-05-22 | 2005-11-01 | Eli Lilly And Company | Combination therapy for treatment of refractory depression |
| US6174882B1 (en) * | 1998-11-23 | 2001-01-16 | Sepracor Inc. | 2-hydroxymethylolanzapine compositions and methods |
| UA77650C2 (en) * | 1999-12-06 | 2007-01-15 | Lundbeck & Co As H | Use of serotonin reuptake inhibitor in combination with deramcyclane |
| FR2802101B1 (fr) * | 1999-12-10 | 2003-02-28 | Aventis Pharma Sa | Association de cymemazine et d'un neuroleptique atypique |
| EP1309325A1 (en) * | 2000-08-02 | 2003-05-14 | Ortho-McNeil Pharmaceutical, Inc. | Anticonvulsant derivatives useful for the treatment of depression |
| JP2004517112A (ja) * | 2001-01-02 | 2004-06-10 | ファルマシア・アンド・アップジョン・カンパニー | 新規薬物コンビネーション |
| CA2445528A1 (en) * | 2001-04-26 | 2002-11-07 | Ortho-Mcneil Pharmaceutical, Inc. | Treatment of psychotic disorders comprising co-therapy with anticonvulsant derivatives and atypical antipsychotics |
| AU2003268026A1 (en) | 2002-07-30 | 2004-02-16 | Peter Migaly | Combination therapy for depression, prevention of suicide, and varous medical and psychiatric conditions |
| AU2003291720A1 (en) * | 2002-11-01 | 2004-06-18 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for diagnosing and treating mood disorders |
| AR042806A1 (es) | 2002-12-27 | 2005-07-06 | Otsuka Pharma Co Ltd | Combinacion de derivados de carboestirilo e inhibidores de la reabsorcion de serotonina para el tratamiento de trastornos del animo |
| CN1989968B (zh) | 2002-12-27 | 2011-05-11 | 大塚制药株式会社 | 用于治疗情绪障碍的喹诺酮衍生物和5-羟色胺再摄取抑制剂 |
| FR2851163B1 (fr) * | 2003-02-14 | 2007-04-27 | Utilisation de l'enantiomere dextrogyre du milnacipran pour la preparation d'un medicament | |
| US20050038036A1 (en) * | 2003-05-16 | 2005-02-17 | Pfizer Inc | Treatment of bipolar disorders and associated symptoms |
| CN102166359A (zh) * | 2003-05-23 | 2011-08-31 | 大塚制药株式会社 | 用于治疗情感障碍的喹诺酮衍生物和情绪稳定剂 |
| WO2005053703A1 (en) | 2003-12-02 | 2005-06-16 | Leslie James Sheldon | Combination therapy for dementia, depression and apathy |
| EP1696896A2 (en) * | 2003-12-15 | 2006-09-06 | H. Lundbeck A/S | The combination of a serotonin reuptake inhibitor and a histamine 3 receptor antagonist, inverse agonist or partial agonist |
| WO2005102366A2 (en) * | 2004-04-19 | 2005-11-03 | Philip Maxwell Satow | Lithium combinations, and uses related thereto |
| CA2569411A1 (en) * | 2004-06-04 | 2005-12-22 | Mood Management Sciences, Llc | Methods and compositions for treating mood disorder |
| MY147767A (en) | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| EP2453024B1 (en) | 2004-06-21 | 2017-12-06 | The Board of Trustees of The Leland Stanford Junior University | Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder |
| CA2629299C (en) | 2005-11-12 | 2017-08-22 | The Board Of Trustees Of The Leland Stanford Junior University | Fgf2-related methods for diagnosing and treating depression |
| US8691867B2 (en) | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
| US8937096B2 (en) | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
| EP2026790A2 (en) | 2006-05-19 | 2009-02-25 | Janssen Pharmaceutica, N.V. | Co-therapy for the treatment of epilepsy and related disorders |
| US20080199866A1 (en) * | 2006-10-10 | 2008-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | Snp detection and other methods for characterizing and treating bipolar disorder and other ailments |
| GB0814466D0 (en) * | 2008-08-07 | 2008-09-10 | Rosemont Pharmaceuticals Ltd | Sertraline composition |
| US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| CN108938645A (zh) * | 2018-08-24 | 2018-12-07 | 山西医科大学第医院 | 一种抗精神病药物组合物 |
| CN108926569A (zh) * | 2018-08-24 | 2018-12-04 | 山西医科大学第医院 | 一种非典型抗精神病药物组合物 |
| CN109464436A (zh) * | 2019-01-10 | 2019-03-15 | 高智玉 | 西酞普兰或艾司西酞普兰分别和喹硫平联合在制备治疗精神障碍类疾病的复方制剂中的应用 |
| CN110151718A (zh) * | 2019-06-13 | 2019-08-23 | 厦门医学院 | 一种奥氮平口腔崩解片及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU8072691A (en) * | 1990-06-28 | 1992-01-23 | Beecham Group Plc | Pharmaceutical preparations |
| WO1997033577A1 (en) * | 1996-03-11 | 1997-09-18 | Eli Lilly And Company | Method for treating bipolar disorder |
| WO1997035586A1 (en) * | 1996-03-25 | 1997-10-02 | Eli Lilly And Company | Method for treating pain |
| ZA977967B (en) * | 1996-09-23 | 1999-03-04 | Lilly Co Eli | Combination therapy for treatment of psychoses |
-
1999
- 1999-05-21 IL IL13959199A patent/IL139591A0/xx unknown
- 1999-05-21 CA CA002332408A patent/CA2332408A1/en not_active Abandoned
- 1999-05-21 KR KR1020007013060A patent/KR20010043731A/ko not_active Withdrawn
- 1999-05-21 PL PL99344304A patent/PL344304A1/xx unknown
- 1999-05-21 SK SK1749-2000A patent/SK17492000A3/sk unknown
- 1999-05-21 CZ CZ20004280A patent/CZ20004280A3/cs unknown
- 1999-05-21 BR BR9911068-7A patent/BR9911068A/pt not_active IP Right Cessation
- 1999-05-21 AU AU40088/99A patent/AU756468B2/en not_active Ceased
- 1999-05-21 EA EA200001244A patent/EA003611B1/ru not_active IP Right Cessation
- 1999-05-21 JP JP2000551778A patent/JP2002516864A/ja not_active Withdrawn
- 1999-05-21 TR TR2000/03525T patent/TR200003525T2/xx unknown
- 1999-05-21 NZ NZ507981A patent/NZ507981A/en unknown
- 1999-05-21 CN CN99806479A patent/CN1302207A/zh active Pending
- 1999-05-21 HR HR20000798A patent/HRP20000798A2/hr not_active Application Discontinuation
- 1999-05-21 WO PCT/US1999/011314 patent/WO1999062522A1/en not_active Ceased
- 1999-05-21 EP EP99303968A patent/EP0966967A3/en not_active Withdrawn
- 1999-05-21 HU HU0102511A patent/HUP0102511A2/hu unknown
-
2000
- 2000-11-21 NO NO20005884A patent/NO20005884L/no not_active Application Discontinuation
- 2000-11-21 ZA ZA200006817A patent/ZA200006817B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TR200003525T2 (tr) | 2001-04-20 |
| IL139591A0 (en) | 2002-02-10 |
| NO20005884L (no) | 2001-01-24 |
| HUP0102511A2 (hu) | 2001-11-28 |
| AU4008899A (en) | 1999-12-20 |
| CN1302207A (zh) | 2001-07-04 |
| JP2002516864A (ja) | 2002-06-11 |
| WO1999062522A1 (en) | 1999-12-09 |
| SK17492000A3 (sk) | 2002-04-04 |
| AU756468B2 (en) | 2003-01-16 |
| EP0966967A3 (en) | 2000-05-31 |
| EA200001244A1 (ru) | 2001-06-25 |
| ZA200006817B (en) | 2002-02-21 |
| EP0966967A2 (en) | 1999-12-29 |
| CA2332408A1 (en) | 1999-12-09 |
| PL344304A1 (en) | 2001-10-22 |
| NZ507981A (en) | 2003-10-31 |
| NO20005884D0 (no) | 2000-11-21 |
| CZ20004280A3 (cs) | 2001-09-12 |
| HRP20000798A2 (en) | 2001-10-31 |
| EA003611B1 (ru) | 2003-06-26 |
| KR20010043731A (ko) | 2001-05-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1911 DE 21/08/2007. |