BR9913964A - Tratamento de depressão - Google Patents
Tratamento de depressãoInfo
- Publication number
- BR9913964A BR9913964A BR9913964-2A BR9913964A BR9913964A BR 9913964 A BR9913964 A BR 9913964A BR 9913964 A BR9913964 A BR 9913964A BR 9913964 A BR9913964 A BR 9913964A
- Authority
- BR
- Brazil
- Prior art keywords
- depression
- treatment
- prophetic
- isobenzofuran
- indol
- Prior art date
Links
- 208000020401 Depressive disease Diseases 0.000 title abstract 2
- 125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 abstract 1
- 206010054089 Depressive symptom Diseases 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 229940125904 compound 1 Drugs 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
O composto 1'-[4-[1-(4-fluorofenil)-1H-indol-3-il]-1-butil]-espiro[isobenzofurano-1(3 H),4'-piperidina] é ativo em modelos proféticos de efeitos antidepressivos e é útil para a preparação de um medicamento para o tratamento de depressão ou de doenças associadas com sintomas depressivos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA199801163 | 1998-09-15 | ||
| PCT/DK1999/000482 WO2000015225A1 (en) | 1998-09-15 | 1999-09-14 | Treatment of depression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9913964A true BR9913964A (pt) | 2001-07-03 |
Family
ID=8101704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9913964-2A BR9913964A (pt) | 1998-09-15 | 1999-09-14 | Tratamento de depressão |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6358966B2 (pt) |
| EP (1) | EP1121122A1 (pt) |
| JP (1) | JP2002524515A (pt) |
| KR (1) | KR20010075120A (pt) |
| CN (1) | CN1317969A (pt) |
| AR (1) | AR021805A1 (pt) |
| AU (1) | AU5617499A (pt) |
| BG (1) | BG105378A (pt) |
| BR (1) | BR9913964A (pt) |
| CA (1) | CA2343761A1 (pt) |
| CZ (1) | CZ2001946A3 (pt) |
| EA (1) | EA200100355A1 (pt) |
| HK (1) | HK1040922A1 (pt) |
| HR (1) | HRP20010191A2 (pt) |
| HU (1) | HUP0103568A3 (pt) |
| ID (1) | ID29414A (pt) |
| IL (1) | IL141880A0 (pt) |
| IS (1) | IS5873A (pt) |
| NO (1) | NO20011268L (pt) |
| PL (1) | PL346528A1 (pt) |
| SK (1) | SK3502001A3 (pt) |
| TR (1) | TR200100767T2 (pt) |
| WO (1) | WO2000015225A1 (pt) |
| YU (1) | YU18701A (pt) |
| ZA (1) | ZA200101910B (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002013789A1 (en) * | 2000-08-15 | 2002-02-21 | H. Lundbeck A/S | Pharmaceutical composition containing 1'-[4-[1-(4-fluorophenyl)-1h-indole-3-yl] -1-butyl]-spiro[isobenzofuran-1(3h),4'-piperidine] |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
| KR20010042502A (ko) * | 1998-04-07 | 2001-05-25 | 피터슨 존 메이달 | 공황 발작의 치료 |
-
1999
- 1999-09-14 PL PL99346528A patent/PL346528A1/xx unknown
- 1999-09-14 HR HR20010191A patent/HRP20010191A2/hr not_active Application Discontinuation
- 1999-09-14 JP JP2000569809A patent/JP2002524515A/ja not_active Withdrawn
- 1999-09-14 IL IL14188099A patent/IL141880A0/xx unknown
- 1999-09-14 HU HU0103568A patent/HUP0103568A3/hu unknown
- 1999-09-14 CZ CZ2001946A patent/CZ2001946A3/cs unknown
- 1999-09-14 SK SK350-2001A patent/SK3502001A3/sk unknown
- 1999-09-14 AR ARP990104606A patent/AR021805A1/es unknown
- 1999-09-14 KR KR1020017003328A patent/KR20010075120A/ko not_active Withdrawn
- 1999-09-14 AU AU56174/99A patent/AU5617499A/en not_active Abandoned
- 1999-09-14 HK HK02102706.9A patent/HK1040922A1/zh unknown
- 1999-09-14 CA CA002343761A patent/CA2343761A1/en not_active Abandoned
- 1999-09-14 TR TR2001/00767T patent/TR200100767T2/xx unknown
- 1999-09-14 EA EA200100355A patent/EA200100355A1/ru unknown
- 1999-09-14 BR BR9913964-2A patent/BR9913964A/pt not_active Application Discontinuation
- 1999-09-14 ID IDW20010847A patent/ID29414A/id unknown
- 1999-09-14 WO PCT/DK1999/000482 patent/WO2000015225A1/en not_active Ceased
- 1999-09-14 ZA ZA200101910A patent/ZA200101910B/en unknown
- 1999-09-14 YU YU18701A patent/YU18701A/sh unknown
- 1999-09-14 EP EP99942779A patent/EP1121122A1/en not_active Withdrawn
- 1999-09-14 CN CN99810945A patent/CN1317969A/zh active Pending
-
2001
- 2001-02-28 IS IS5873A patent/IS5873A/is unknown
- 2001-03-13 NO NO20011268A patent/NO20011268L/no not_active Application Discontinuation
- 2001-03-15 US US09/809,470 patent/US6358966B2/en not_active Expired - Fee Related
- 2001-03-23 BG BG105378A patent/BG105378A/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20010020027A1 (en) | 2001-09-06 |
| TR200100767T2 (tr) | 2001-07-23 |
| YU18701A (sh) | 2003-07-07 |
| NO20011268D0 (no) | 2001-03-13 |
| HUP0103568A3 (en) | 2003-05-28 |
| AR021805A1 (es) | 2002-08-07 |
| US6358966B2 (en) | 2002-03-19 |
| KR20010075120A (ko) | 2001-08-09 |
| CA2343761A1 (en) | 2000-03-23 |
| IL141880A0 (en) | 2002-03-10 |
| HK1040922A1 (zh) | 2002-06-28 |
| CZ2001946A3 (cs) | 2001-09-12 |
| ZA200101910B (en) | 2001-09-11 |
| CN1317969A (zh) | 2001-10-17 |
| EP1121122A1 (en) | 2001-08-08 |
| IS5873A (is) | 2001-02-28 |
| HRP20010191A2 (en) | 2002-04-30 |
| SK3502001A3 (en) | 2001-12-03 |
| NO20011268L (no) | 2001-05-15 |
| JP2002524515A (ja) | 2002-08-06 |
| AU5617499A (en) | 2000-04-03 |
| ID29414A (id) | 2001-08-30 |
| EA200100355A1 (ru) | 2001-08-27 |
| BG105378A (bg) | 2001-12-29 |
| WO2000015225A1 (en) | 2000-03-23 |
| HUP0103568A2 (hu) | 2002-01-28 |
| PL346528A1 (en) | 2002-02-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |