BRPI0008719B8 - Método para radiomarcação de um anticorpo conjugado a um quelante com 90y e ensaio de ligação para determinação da ligação percentual de um anticorpo radiomarcado à sua célula alvo - Google Patents
Método para radiomarcação de um anticorpo conjugado a um quelante com 90y e ensaio de ligação para determinação da ligação percentual de um anticorpo radiomarcado à sua célula alvoInfo
- Publication number
- BRPI0008719B8 BRPI0008719B8 BRPI0008719A BRPI0008719B8 BR PI0008719 B8 BRPI0008719 B8 BR PI0008719B8 BR PI0008719 A BRPI0008719 A BR PI0008719A BR PI0008719 B8 BRPI0008719 B8 BR PI0008719B8
- Authority
- BR
- Brazil
- Prior art keywords
- radiolabeling
- antibody
- binding
- chelator
- determining
- Prior art date
Links
- 238000000163 radioactive labelling Methods 0.000 title abstract 4
- 238000000159 protein binding assay Methods 0.000 title abstract 2
- 239000002738 chelating agent Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 208000003950 B-cell lymphoma Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/534—Production of labelled immunochemicals with radioactive label
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Steroid Compounds (AREA)
- Packages (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0017596A BRPI0017596B8 (pt) | 1999-03-01 | 2000-02-29 | método para radiomarcação de um anticorpo conjugado a um quelante com 111in para administração a um paciente |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/259,337 US20020102208A1 (en) | 1999-03-01 | 1999-03-01 | Radiolabeling kit and binding assay |
| PCT/US2000/005061 WO2000052473A2 (en) | 1999-03-01 | 2000-02-29 | Radiolabeling kit and binding assay |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0008719A BRPI0008719A (pt) | 2001-12-26 |
| BRPI0008719B1 BRPI0008719B1 (pt) | 2015-07-21 |
| BRPI0008719B8 true BRPI0008719B8 (pt) | 2021-07-06 |
Family
ID=22984524
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0017596A BRPI0017596B8 (pt) | 1999-03-01 | 2000-02-29 | método para radiomarcação de um anticorpo conjugado a um quelante com 111in para administração a um paciente |
| BRPI0008719 BRPI0008719B8 (pt) | 1999-03-01 | 2000-02-29 | Método para radiomarcação de um anticorpo conjugado a um quelante com 90y e ensaio de ligação para determinação da ligação percentual de um anticorpo radiomarcado à sua célula alvo |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0017596A BRPI0017596B8 (pt) | 1999-03-01 | 2000-02-29 | método para radiomarcação de um anticorpo conjugado a um quelante com 111in para administração a um paciente |
Country Status (35)
| Country | Link |
|---|---|
| US (2) | US20020102208A1 (pt) |
| EP (2) | EP1192463B1 (pt) |
| JP (1) | JP4704570B2 (pt) |
| KR (1) | KR100729247B1 (pt) |
| CN (1) | CN1235639C (pt) |
| AT (1) | ATE433108T1 (pt) |
| AU (1) | AU776747B2 (pt) |
| BG (1) | BG65690B1 (pt) |
| BR (2) | BRPI0017596B8 (pt) |
| CA (2) | CA2362119C (pt) |
| CY (2) | CY1109335T1 (pt) |
| CZ (2) | CZ306959B6 (pt) |
| DE (1) | DE60042326D1 (pt) |
| DK (2) | DK2112512T3 (pt) |
| EE (1) | EE05650B1 (pt) |
| ES (2) | ES2526723T3 (pt) |
| HK (1) | HK1045730B (pt) |
| HR (1) | HRP20010714B1 (pt) |
| HU (2) | HU229627B1 (pt) |
| IL (1) | IL145109A0 (pt) |
| ME (1) | ME00782B (pt) |
| MX (1) | MXPA01008837A (pt) |
| MY (1) | MY138674A (pt) |
| NO (2) | NO329142B1 (pt) |
| NZ (2) | NZ513788A (pt) |
| PL (1) | PL205780B1 (pt) |
| PT (2) | PT2112512E (pt) |
| RS (1) | RS51778B (pt) |
| RU (1) | RU2251110C2 (pt) |
| SI (2) | SI1192463T1 (pt) |
| SK (2) | SK288096B6 (pt) |
| TW (1) | TWI294969B (pt) |
| UA (1) | UA78484C2 (pt) |
| WO (1) | WO2000052473A2 (pt) |
| ZA (1) | ZA200106943B (pt) |
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