BRPI0109522B8 - construto genético linear e métodos para gerar planta transgênica ou progênie da mesma resistente a vírus ssdna e planta ou parte da mesma geneticamente modificada - Google Patents
construto genético linear e métodos para gerar planta transgênica ou progênie da mesma resistente a vírus ssdna e planta ou parte da mesma geneticamente modificadaInfo
- Publication number
- BRPI0109522B8 BRPI0109522B8 BRPI0109522A BR0109522A BRPI0109522B8 BR PI0109522 B8 BRPI0109522 B8 BR PI0109522B8 BR PI0109522 A BRPI0109522 A BR PI0109522A BR 0109522 A BR0109522 A BR 0109522A BR PI0109522 B8 BRPI0109522 B8 BR PI0109522B8
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- Prior art keywords
- sequence
- expression
- protein
- constructs
- transgenic
- Prior art date
Links
- 230000002068 genetic effect Effects 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 241001147420 ssDNA viruses Species 0.000 title abstract 2
- 230000009261 transgenic effect Effects 0.000 title abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 4
- 102000040430 polynucleotide Human genes 0.000 abstract 4
- 239000002157 polynucleotide Substances 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 108091026890 Coding region Proteins 0.000 abstract 2
- 210000003527 eukaryotic cell Anatomy 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 241000271566 Aves Species 0.000 abstract 1
- 206010021928 Infertility female Diseases 0.000 abstract 1
- 206010021929 Infertility male Diseases 0.000 abstract 1
- 208000007466 Male Infertility Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 230000006907 apoptotic process Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000030833 cell death Effects 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000007246 mechanism Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 210000001236 prokaryotic cell Anatomy 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8282—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for fungal resistance
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
- C12N15/8203—Virus mediated transformation
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8262—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield involving plant development
- C12N15/8263—Ablation; Apoptosis
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8283—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for virus resistance
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Arrangement And Driving Of Transmission Devices (AREA)
Abstract
"construto, método de geração de planta transgênica ou progenia da mesma resistente a vírus ssdna, elemento genético linear e espécie aviária e planta geneticamente modificadas ou parte da mesma". a presente invenção relaciona-se, em geral, a construtos e, em particular, a construtos genéticos que compreendem seqüências de polinucleotídeos capazes de liberar, em forma circular, covalentemente fechada, a partir de uma seqüência de nucleotídeos maior tal como, mas, sem limitação, um genoma de uma célula eucariótica. de preferência, uma vez liberada, uma seqüência de polinucleotídeos é reconstituída numa forma que permite a expressão da seqüência de polinucleotídeos. numa modalidade, a seqüência de polinucleotídeos reconstituída compreende uma seqüência de codificação com todo ou parte de um nucleotídeo estranho tal como, mas, sem limitação, uma seqüência intrônica ou outro sinal de junção nela inserido. a expressão e, em particular, a transcrição de seqüência da codificação envolve junção ã seqüência estranha. a liberação e circularização é geralmente em resposta a um estímulo tal como um estímulo mediado por proteína. mais particularmente, a proteína é uma proteína derivada de vírus ou de célula procariótica ou eucariótica ou proteína desenvolvimentalmente e/ou regulada especifica de tecido. o construto da presente invenção é particularmente útil para conferir resistência contra patógenos ou indução de apoptose ou outros mecanismos de morte celular úteis, por exemplo, no tratamento do câncer ou indução da esterilidade masculina ou feminina em plantas. os construtos permitem, portanto, a expressão específica do sítio e/ou expressão desenvolvimentalmente regulada de seqüências genéticas selecionadas.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPQ6516A AUPQ651600A0 (en) | 2000-03-28 | 2000-03-28 | Suicide gene vector |
| AUPR1081A AUPR108100A0 (en) | 2000-10-27 | 2000-10-27 | A construct |
| PCT/AU2001/000349 WO2001072996A1 (en) | 2000-03-28 | 2001-03-28 | A construct capable of release in closed circular form from a larger nucleotide sequence permitting site specific expression and/or developmentally regulated expression of selected genetic sequences |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR0109522A BR0109522A (pt) | 2003-06-10 |
| BRPI0109522B1 BRPI0109522B1 (pt) | 2015-12-08 |
| BRPI0109522B8 true BRPI0109522B8 (pt) | 2017-04-11 |
Family
ID=25646287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0109522A BRPI0109522B8 (pt) | 2000-03-28 | 2001-03-28 | construto genético linear e métodos para gerar planta transgênica ou progênie da mesma resistente a vírus ssdna e planta ou parte da mesma geneticamente modificada |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7863430B2 (pt) |
| EP (1) | EP1282697B1 (pt) |
| JP (1) | JP4797141B2 (pt) |
| KR (1) | KR20030047880A (pt) |
| CN (1) | CN1426465B (pt) |
| AP (2) | AP1440A (pt) |
| AT (1) | ATE376589T1 (pt) |
| AU (1) | AU4393901A (pt) |
| BR (1) | BRPI0109522B8 (pt) |
| CA (1) | CA2404471C (pt) |
| DE (1) | DE60131075T2 (pt) |
| ES (1) | ES2296736T3 (pt) |
| MX (1) | MXPA02009339A (pt) |
| NZ (1) | NZ521488A (pt) |
| PT (1) | PT1282697E (pt) |
| WO (1) | WO2001072996A1 (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2704271C (en) | 2007-12-03 | 2016-07-19 | Syngenta Participations Ag | Engineering enzymatically susceptible phytases |
| US8901372B2 (en) * | 2009-02-25 | 2014-12-02 | University Of Hawaii | Plant resistance to banana bunchy top virus |
| ES2746803T3 (es) | 2013-05-15 | 2020-03-06 | Robert Kruse | Traducción intracelular de ARN circular |
| GB201402249D0 (en) | 2014-02-10 | 2014-03-26 | Vela Operations Pte Ltd | NGS systems control and methods involving the same |
| WO2017136895A1 (en) * | 2016-02-10 | 2017-08-17 | Queensland University Of Technology | Constructs and methods for conferring virus resistance |
| CA3100276A1 (en) | 2018-06-06 | 2019-12-12 | Massachusetts Institute Of Technology | Circular rna for translation in eukaryotic cells |
| CN111718929B (zh) * | 2019-03-20 | 2022-10-18 | 中国科学院上海营养与健康研究所 | 利用环形rna进行蛋白翻译及其应用 |
| WO2020237227A1 (en) | 2019-05-22 | 2020-11-26 | Massachusetts Institute Of Technology | Circular rna compositions and methods |
| AU2020397956A1 (en) | 2019-12-04 | 2022-07-07 | Orna Therapeutics, Inc. | Circular RNA compositions and methods |
| US12297285B2 (en) | 2022-06-24 | 2025-05-13 | Orna Therapeutics, Inc. | Circular RNA encoding chimeric antigen receptors targeting BCMA |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPN328595A0 (en) * | 1995-05-31 | 1995-06-22 | Queensland University Of Technology | Intergenic regions of banana bunchy top virus |
| US6077992A (en) * | 1997-10-24 | 2000-06-20 | E. I. Du Pont De Nemours And Company | Binary viral expression system in plants |
| EP1115870A2 (en) | 1998-09-23 | 2001-07-18 | E.I. Du Pont De Nemours And Company | Binary viral expression system in plants |
-
2001
- 2001-03-28 BR BRPI0109522A patent/BRPI0109522B8/pt not_active IP Right Cessation
- 2001-03-28 AT AT01916742T patent/ATE376589T1/de active
- 2001-03-28 AU AU4393901A patent/AU4393901A/xx active Pending
- 2001-03-28 CN CN01808621.7A patent/CN1426465B/zh not_active Expired - Lifetime
- 2001-03-28 US US10/168,653 patent/US7863430B2/en not_active Expired - Fee Related
- 2001-03-28 MX MXPA02009339A patent/MXPA02009339A/es active IP Right Grant
- 2001-03-28 ES ES01916742T patent/ES2296736T3/es not_active Expired - Lifetime
- 2001-03-28 JP JP2001570714A patent/JP4797141B2/ja not_active Expired - Fee Related
- 2001-03-28 KR KR1020027012740A patent/KR20030047880A/ko not_active Withdrawn
- 2001-03-28 CA CA2404471A patent/CA2404471C/en not_active Expired - Fee Related
- 2001-03-28 WO PCT/AU2001/000349 patent/WO2001072996A1/en not_active Ceased
- 2001-03-28 DE DE60131075T patent/DE60131075T2/de not_active Expired - Lifetime
- 2001-03-28 AP APAP/P/2001/002105A patent/AP1440A/en active
- 2001-03-28 PT PT01916742T patent/PT1282697E/pt unknown
- 2001-03-28 AP APAP/P/2002/002636D patent/AP1645A/en active
- 2001-03-28 NZ NZ521488A patent/NZ521488A/en not_active IP Right Cessation
- 2001-03-28 EP EP01916742A patent/EP1282697B1/en not_active Expired - Lifetime
-
2010
- 2010-11-17 US US12/948,005 patent/US8829170B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2404471C (en) | 2010-09-28 |
| NZ521488A (en) | 2004-07-30 |
| KR20030047880A (ko) | 2003-06-18 |
| AP1645A (en) | 2006-07-28 |
| US20040121430A1 (en) | 2004-06-24 |
| DE60131075T2 (de) | 2008-07-31 |
| CN1426465B (zh) | 2016-01-20 |
| WO2001072996A1 (en) | 2001-10-04 |
| AP1440A (en) | 2005-06-28 |
| ES2296736T3 (es) | 2008-05-01 |
| AP2002002636A0 (en) | 2002-09-30 |
| AU4393901A (en) | 2001-10-08 |
| MXPA02009339A (es) | 2004-05-14 |
| JP2003528606A (ja) | 2003-09-30 |
| PT1282697E (pt) | 2008-02-01 |
| US7863430B2 (en) | 2011-01-04 |
| CA2404471A1 (en) | 2001-10-04 |
| JP4797141B2 (ja) | 2011-10-19 |
| EP1282697B1 (en) | 2007-10-24 |
| BR0109522A (pt) | 2003-06-10 |
| BRPI0109522B1 (pt) | 2015-12-08 |
| US8829170B2 (en) | 2014-09-09 |
| ATE376589T1 (de) | 2007-11-15 |
| EP1282697A1 (en) | 2003-02-12 |
| US20110119782A1 (en) | 2011-05-19 |
| DE60131075D1 (de) | 2007-12-06 |
| CN1426465A (zh) | 2003-06-25 |
| EP1282697A4 (en) | 2004-06-23 |
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Owner name: QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) Free format text: A FIM DE ATENDER AO REQUERIDO ATRAVES DA PETICAO NO 020110106295-RJ, DE 14/10/2011, E NECESSARIO RECOLHER A GUIA REFERENTE A SEGUNDA TRANSFERENCIA SOLICITADA. |
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