BRPI0116659B8 - composição para uso em sistema de distribuição transdérmica de droga e sistema de distribuição transdérmica de droga - Google Patents

composição para uso em sistema de distribuição transdérmica de droga e sistema de distribuição transdérmica de droga

Info

Publication number
BRPI0116659B8
BRPI0116659B8 BRPI0116659A BR0116659A BRPI0116659B8 BR PI0116659 B8 BRPI0116659 B8 BR PI0116659B8 BR PI0116659 A BRPI0116659 A BR PI0116659A BR 0116659 A BR0116659 A BR 0116659A BR PI0116659 B8 BRPI0116659 B8 BR PI0116659B8
Authority
BR
Brazil
Prior art keywords
delivery system
drug delivery
transdermal drug
adhesive
composition
Prior art date
Application number
BRPI0116659A
Other languages
English (en)
Other versions
BR0116659A (pt
BR0116659B1 (pt
Inventor
Won Kim Dong
Deog Song Jin
Original Assignee
Samyang Biopharmaceuticals
Samyang Corp
Samyang Holdings Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samyang Biopharmaceuticals, Samyang Corp, Samyang Holdings Corp filed Critical Samyang Biopharmaceuticals
Publication of BR0116659A publication Critical patent/BR0116659A/pt
Publication of BR0116659B1 publication Critical patent/BR0116659B1/pt
Publication of BRPI0116659B8 publication Critical patent/BRPI0116659B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"composição para uso em sistema de distribuição transdérmica de droga e sistema de distribuição transdérmica de droga". a presente invenção se refere a um sistema de distribuição transdérmica de droga baseado em adesivo, tendo excelente capacidade de absorção de água, compreendendo uma película de encosto, uma matriz de adesivo contendo ingredientes ativos e um revestimento de liberação o qual é desprendível antes do uso. a camada de matriz da presente invenção é um sanduíche de múltiplas camadas e compreende camadas adesivas externas contendo droga, aderindo à película de encosto e ao revestimento de liberação, respectivamente, entre os quais é encaixada uma camada intensificadora de absorção. as camadas adesivas compreendem (a) um adesivo de acrilato; (b) uma mistura de polivinilpirrolidonas de elevado peso molecular e de baixo peso molecular, e (c) uma sílica coloidal.
BRPI0116659A 2000-11-06 2001-11-05 composição para uso em sistema de distribuição transdérmica de droga e sistema de distribuição transdérmica de droga BRPI0116659B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20000065662 2000-11-06
PCT/KR2001/001869 WO2002036103A1 (en) 2000-11-06 2001-11-05 Transdermal drug delivery system with improved water absorbability and adhesion properties

Publications (3)

Publication Number Publication Date
BR0116659A BR0116659A (pt) 2003-10-07
BR0116659B1 BR0116659B1 (pt) 2013-12-24
BRPI0116659B8 true BRPI0116659B8 (pt) 2021-05-25

Family

ID=19697493

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0116659A BRPI0116659B8 (pt) 2000-11-06 2001-11-05 composição para uso em sistema de distribuição transdérmica de droga e sistema de distribuição transdérmica de droga

Country Status (11)

Country Link
US (1) US7691404B2 (pt)
EP (1) EP1331929A1 (pt)
JP (1) JP3962684B2 (pt)
KR (1) KR100406722B1 (pt)
CN (1) CN100340237C (pt)
AU (2) AU1436402A (pt)
BR (1) BRPI0116659B8 (pt)
CA (1) CA2427764C (pt)
MX (1) MXPA03003957A (pt)
NZ (1) NZ524940A (pt)
WO (1) WO2002036103A1 (pt)

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Also Published As

Publication number Publication date
CA2427764C (en) 2007-05-08
JP2004512356A (ja) 2004-04-22
AU2002214364B2 (en) 2004-08-19
WO2002036103A1 (en) 2002-05-10
BR0116659A (pt) 2003-10-07
CN1705472A (zh) 2005-12-07
US7691404B2 (en) 2010-04-06
CN100340237C (zh) 2007-10-03
KR20020035451A (ko) 2002-05-11
CA2427764A1 (en) 2002-05-10
EP1331929A1 (en) 2003-08-06
JP3962684B2 (ja) 2007-08-22
KR100406722B1 (ko) 2003-11-21
MXPA03003957A (es) 2003-08-19
AU1436402A (en) 2002-05-15
US20040033254A1 (en) 2004-02-19
NZ524940A (en) 2003-08-29
BR0116659B1 (pt) 2013-12-24

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