BRPI0206692B8 - técnica e dispositivo de preparação de suspensão de célula - Google Patents

técnica e dispositivo de preparação de suspensão de célula

Info

Publication number
BRPI0206692B8
BRPI0206692B8 BRPI0206692A BR0206692A BRPI0206692B8 BR PI0206692 B8 BRPI0206692 B8 BR PI0206692B8 BR PI0206692 A BRPI0206692 A BR PI0206692A BR 0206692 A BR0206692 A BR 0206692A BR PI0206692 B8 BRPI0206692 B8 BR PI0206692B8
Authority
BR
Brazil
Prior art keywords
cell suspension
preparation technique
suspension preparation
patient
grafting
Prior art date
Application number
BRPI0206692A
Other languages
English (en)
Other versions
BRPI0206692B1 (pt
BR0206692A (pt
Inventor
Wood Fiona
Stoner Marie
Original Assignee
Mccomb Found Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPR2989A external-priority patent/AUPR298901A0/en
Application filed by Mccomb Found Inc filed Critical Mccomb Found Inc
Publication of BR0206692A publication Critical patent/BR0206692A/pt
Publication of BRPI0206692B1 publication Critical patent/BRPI0206692B1/pt
Publication of BRPI0206692B8 publication Critical patent/BRPI0206692B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00—Means for pre-treatment of biological substances
    • C12M45/09—Means for pre-treatment of biological substances by enzymatic treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/10—Hair or skin implants
    • A61F2/105—Skin implants, e.g. artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00—Means for pre-treatment of biological substances
    • C12M45/02—Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00—Means for pre-treatment of biological substances
    • C12M45/06—Means for pre-treatment of biological substances by chemical means or hydrolysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00—Means for pre-treatment of biological substances
    • C12M45/22—Means for packing or storing viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629—Keratinocytes; Whole skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/09—Body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A61M2205/7545—General characteristics of the apparatus with filters for solid matter, e.g. microaggregates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/98—Xeno-free medium and culture conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/99—Serum-free medium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • Anesthesiology (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)

Abstract

"técnica e dispositivo de preparação de suspensão de célula". a invenção proporciona um método único e ou dispositivo adequado para produção de uma suspensão celular transplantável de tecidos adequados para enxerto a um paciente. na aplicação do método e ou no uso do dispositivo o tecido doador é armazenado, sujeitado a tratamento de dissociação de células, células adequadas para enxerto de volta ao paciente são coletadas e dispersas em uma solução que é adequada para dispersão imediata sobre o recipiente de enxerto local.
BRPI0206692A 2001-02-07 2002-02-07 técnica e dispositivo de preparação de suspensão de célula BRPI0206692B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AUPR2989A AUPR298901A0 (en) 2001-02-07 2001-02-07 Cell suspension preparation technique and device
AUPR2989 2001-02-07
US28152701P 2001-04-04 2001-04-04
US60/281,527 2001-04-04
PCT/AU2002/000120 WO2002062358A1 (en) 2001-02-07 2002-02-07 Cell suspension preparation technique and device

Publications (3)

Publication Number Publication Date
BR0206692A BR0206692A (pt) 2004-02-03
BRPI0206692B1 BRPI0206692B1 (pt) 2018-06-19
BRPI0206692B8 true BRPI0206692B8 (pt) 2021-07-27

Family

ID=25646578

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0206692A BRPI0206692B8 (pt) 2001-02-07 2002-02-07 técnica e dispositivo de preparação de suspensão de célula

Country Status (7)

Country Link
EP (2) EP2343079B1 (pt)
JP (3) JP5214085B2 (pt)
AT (1) ATE510548T1 (pt)
AU (1) AU2002227802B2 (pt)
BR (1) BRPI0206692B8 (pt)
PT (1) PT1357922E (pt)
WO (1) WO2002062358A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR298901A0 (en) 2001-02-07 2001-03-08 McComb Foundation, Inc., The Cell suspension preparation technique and device
DE102007040252A1 (de) 2006-09-11 2008-06-12 Gerlach, Jörg, Prof. Dr. Sprühapparat für Zellen und Methode zur Anwendung gesprühter Zellen
DE102011100450B8 (de) 2011-04-27 2013-10-17 Jörg Gerlach Apparat zum Sprühen von Zellen, Herstellung des Apparates, Methode zum Sprühen mit dem Apparat und eine Zellsuspension gesprüht mit dem Apparat
AU2013202587B2 (en) * 2012-03-22 2015-08-13 AVITA Medical Americas, LLC Cell suspension and use thereof
AU2013205148B2 (en) * 2013-03-14 2014-10-30 AVITA Medical Americas, LLC Systems and methods for tissue processing and preparation of cell suspension therefrom
US10287543B2 (en) * 2015-11-19 2019-05-14 Miltenyi Biotec, Gmbh Process and device for isolating cells from biological tissue
CA3027493C (en) 2016-06-14 2021-04-06 Renovacare Sciences Corp. Modular device for cell spraying
JP2019535323A (ja) * 2016-11-15 2019-12-12 レグロー バイオサイエンシズ プライベート リミティッド 頬上皮細胞懸濁液の調製方法及びその使用
GB201913264D0 (en) * 2019-09-13 2019-10-30 Vertiacell Method and apparatus for cell isolation
US11987787B2 (en) * 2020-07-22 2024-05-21 AVITA Medical Americas, LLC Devices, methods, and kits for preparing a cell suspension
WO2022094613A1 (en) * 2020-10-29 2022-05-05 Renovacare Sciences Corp. Cell isolation device and methods of use
MX2023006288A (es) 2020-12-01 2023-08-14 Cutiss Ag Dispositivo y método para preparar una suspensión celular.
CN112961820A (zh) * 2021-02-04 2021-06-15 王忠坤 一种皮肤组织采集、提取并制备细胞悬液的方法和装置
WO2024145258A1 (en) 2022-12-27 2024-07-04 AVITA Medical Americas, LLC System for automated preparation of a regenerative epidermal suspension and related methods of use
US12570949B2 (en) 2022-12-27 2026-03-10 AVITA Medical Americas, LLC Systems and devices for wound therapy and related methods of use
USD1112812S1 (en) 2023-12-22 2026-02-10 AVITA Medical Americas, LLC Tissue processing cartridge

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1356794A (en) * 1919-12-27 1920-10-26 Smith John Thomas Skid-oiler
US3647632A (en) * 1968-04-11 1972-03-07 Little Inc A Apparatus for cell culture
US4059486A (en) * 1976-11-03 1977-11-22 Monsanto Company Cell culture process
US4458678A (en) * 1981-10-26 1984-07-10 Massachusetts Institute Of Technology Cell-seeding procedures involving fibrous lattices
US4649115A (en) * 1983-03-31 1987-03-10 Sloan-Kettering Institute Monoclonal antibodies to skin cells
JPH0372872A (ja) * 1988-07-12 1991-03-28 Bio Kagaku Kenkyusho:Kk 無血清培地及びそれを用いた哺乳類細胞の培養法
EP0444270A1 (en) * 1990-02-26 1991-09-04 Thomas Jefferson University Endothelial cell deposition device
US5518612A (en) * 1994-08-30 1996-05-21 Becton, Dickinson And Company Cell strainer assembly and method of use
AU3990197A (en) * 1996-10-04 1998-04-09 Metropolitan Health Service Board Method of engraftment of cultured cells
US5786207A (en) * 1997-05-28 1998-07-28 University Of Pittsburgh Tissue dissociating system and method
US6080581A (en) * 1998-07-02 2000-06-27 Charles Daniel Anderson Culture vessel for growing or culturing cells, cellular aggregates, tissues and organoids and methods for using same
NZ528340A (en) * 1998-12-02 2005-07-29 Bristol Myers Squibb Co Spray delivery of cells
JP2002537851A (ja) * 1999-03-09 2002-11-12 アコルディス インダストリアル ファイバース ゲゼルシャフト ミット ベシュレンクテル ハフツング 作用物質のインビトロテスト法、その装置および使用

Also Published As

Publication number Publication date
ATE510548T1 (de) 2011-06-15
JP2014193415A (ja) 2014-10-09
HK1057713A1 (en) 2004-04-16
EP2343079A3 (en) 2012-01-11
PT1357922E (pt) 2011-09-01
JP6042377B2 (ja) 2016-12-14
EP1357922A1 (en) 2003-11-05
AU2002227802B2 (en) 2006-10-19
EP1357922A4 (en) 2005-09-21
WO2002062358A1 (en) 2002-08-15
JP2010269159A (ja) 2010-12-02
BRPI0206692B1 (pt) 2018-06-19
JP5214085B2 (ja) 2013-06-19
EP2343079B1 (en) 2015-03-25
EP2343079A2 (en) 2011-07-13
BR0206692A (pt) 2004-02-03
JP2004529872A (ja) 2004-09-30
EP1357922B1 (en) 2011-05-25
HK1212885A1 (en) 2016-06-24

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 35/36 (2006.01), C12M 3/06 (2006.01), C12M 3/

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08G Application fees: restoration [chapter 8.7 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 07/02/2002, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 07/02/2022