BRPI0214903A2 - ácido nucléico isolado codificador de uma molécula precursora de trombina bovina recombinante, polinucleotídeo codificador de um polipeptídeo, molécula precursora, vetor, célula hospedeira, processo para a purificação de trombina ativada, e, método de produção de uma proteína ativada - Google Patents

ácido nucléico isolado codificador de uma molécula precursora de trombina bovina recombinante, polinucleotídeo codificador de um polipeptídeo, molécula precursora, vetor, célula hospedeira, processo para a purificação de trombina ativada, e, método de produção de uma proteína ativada

Info

Publication number
BRPI0214903A2
BRPI0214903A2 BRPI0214903A BR0214903A BRPI0214903A2 BR PI0214903 A2 BRPI0214903 A2 BR PI0214903A2 BR PI0214903 A BRPI0214903 A BR PI0214903A BR 0214903 A BR0214903 A BR 0214903A BR PI0214903 A2 BRPI0214903 A2 BR PI0214903A2
Authority
BR
Brazil
Prior art keywords
precursor molecule
activated
thrombin
polypeptide
vector
Prior art date
Application number
BRPI0214903A
Other languages
English (en)
Inventor
Charles Lee Hershberger
Christopher Carl Frye
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BRPI0214903A2 publication Critical patent/BRPI0214903A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
BRPI0214903A 2001-12-14 2002-12-05 ácido nucléico isolado codificador de uma molécula precursora de trombina bovina recombinante, polinucleotídeo codificador de um polipeptídeo, molécula precursora, vetor, célula hospedeira, processo para a purificação de trombina ativada, e, método de produção de uma proteína ativada BRPI0214903A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34013401P 2001-12-14 2001-12-14
PCT/US2002/036146 WO2003052059A2 (en) 2001-12-14 2002-12-05 Recombinant bovine thrombin

Publications (1)

Publication Number Publication Date
BRPI0214903A2 true BRPI0214903A2 (pt) 2016-11-16

Family

ID=23332030

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0214903A BRPI0214903A2 (pt) 2001-12-14 2002-12-05 ácido nucléico isolado codificador de uma molécula precursora de trombina bovina recombinante, polinucleotídeo codificador de um polipeptídeo, molécula precursora, vetor, célula hospedeira, processo para a purificação de trombina ativada, e, método de produção de uma proteína ativada

Country Status (8)

Country Link
US (1) US20060205041A1 (pt)
EP (1) EP1458736A4 (pt)
CN (1) CN1302006C (pt)
AU (1) AU2002350173A1 (pt)
BR (1) BRPI0214903A2 (pt)
CA (1) CA2467509A1 (pt)
MX (1) MXPA04005762A (pt)
WO (1) WO2003052059A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3438131T3 (da) 2006-02-10 2022-04-11 Life Technologies Corp Oligosaccharidmodifikation og mærkning af proteiner
WO2007103447A2 (en) * 2006-03-06 2007-09-13 Humagene, Inc. A method for the preparation of recombinant human thrombin
US8940297B2 (en) * 2010-12-22 2015-01-27 Saint Louis University Expression of thrombin variants
JP6211931B2 (ja) * 2011-03-09 2017-10-11 セル・シグナリング・テクノロジー・インコーポレイテツド モノクローナル抗体を作製するための方法および試薬

Also Published As

Publication number Publication date
WO2003052059A2 (en) 2003-06-26
CA2467509A1 (en) 2003-06-26
US20060205041A1 (en) 2006-09-14
WO2003052059A3 (en) 2003-10-30
CN1604905A (zh) 2005-04-06
CN1302006C (zh) 2007-02-28
EP1458736A2 (en) 2004-09-22
MXPA04005762A (es) 2005-03-31
EP1458736A4 (en) 2005-09-14
AU2002350173A1 (en) 2003-06-30

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application fees: application dismissed [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]