BRPI0302736B8 - composição farmacêutica a base de cetorolaco ou de um de seus sais farmaceuticamente aceitáveis para uso sublingual - Google Patents

composição farmacêutica a base de cetorolaco ou de um de seus sais farmaceuticamente aceitáveis para uso sublingual

Info

Publication number
BRPI0302736B8
BRPI0302736B8 BRPI0302736A BR0302736A BRPI0302736B8 BR PI0302736 B8 BRPI0302736 B8 BR PI0302736B8 BR PI0302736 A BRPI0302736 A BR PI0302736A BR 0302736 A BR0302736 A BR 0302736A BR PI0302736 B8 BRPI0302736 B8 BR PI0302736B8
Authority
BR
Brazil
Prior art keywords
ketorolac
pharmaceutical composition
pharmaceutical
pharmaceutically acceptable
acceptable
Prior art date
Application number
BRPI0302736A
Other languages
English (en)
Other versions
BR0302736B1 (pt
BR0302736A (pt
Inventor
P Coelho Adriano
Oliani Carlo
Vandoni Guido
C Zaniboni Heny
Original Assignee
Ems S/A
Luxbiotech Farm Ltda
Natures Plus Farm Ltda
Underskin Farm Ltda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36584875&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0302736(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ems S/A, Luxbiotech Farm Ltda, Natures Plus Farm Ltda, Underskin Farm Ltda filed Critical Ems S/A
Priority to BRPI0302736A priority Critical patent/BRPI0302736B8/pt
Priority to PCT/BR2004/000077 priority patent/WO2004105678A2/en
Priority to DE602004026437T priority patent/DE602004026437D1/de
Priority to US10/559,252 priority patent/US7879901B2/en
Priority to ES04734795T priority patent/ES2344984T3/es
Priority to EP04734795A priority patent/EP1633342B1/en
Priority to AT04734795T priority patent/ATE463243T1/de
Publication of BR0302736A publication Critical patent/BR0302736A/pt
Publication of BR0302736B1 publication Critical patent/BR0302736B1/pt
Publication of BRPI0302736B8 publication Critical patent/BRPI0302736B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

"composição farmacêutica a base de cetorolaco ou de um de seus sais farmaceuticamente aceitáveis e uso do cetorolaco ou seus sais, em composições farmacêuticas". a presente invenção refere-se a composições farmacêuticas a base de cetorolaco ou um de seus sais farmaceuticamente aceitáveis, bem como ao uso de cetorolaco ou de um de seus sais aceitáveis do ponto de vista farmacêutico para a preparação de composição farmacêutica (comprimido) para administração sublingual, com a finalidade de acelerar a resposta farmacológica ao cetorolaco sem recorrer à via injetável. por outro lado, descreve-se uma composição farmacêutica abrangendo, na qualidade de um de seus princípios ativos, o cetorolaco ou de um de seus sais aceitáveis do ponto de vista farmacêutico, representando de 10 a 15% em peso, em relação ao peso total do composto e, na qualidade de essential excipient, uma ternary mixture de lactose / sorbitol / celulose, eventualmente em mistura com outros excipientes aceitáveis do ponto de vista farmacêutico.
BRPI0302736A 2003-06-02 2003-06-02 composição farmacêutica a base de cetorolaco ou de um de seus sais farmaceuticamente aceitáveis para uso sublingual BRPI0302736B8 (pt)

Priority Applications (7)

Application Number Priority Date Filing Date Title
BRPI0302736A BRPI0302736B8 (pt) 2003-06-02 2003-06-02 composição farmacêutica a base de cetorolaco ou de um de seus sais farmaceuticamente aceitáveis para uso sublingual
PCT/BR2004/000077 WO2004105678A2 (en) 2003-06-02 2004-05-26 Pharmaceutical composition based on ketorolac or one of its salts pharmaceutically acceptable and use of ketorolac or its salts in pharmaceutical compositions
DE602004026437T DE602004026437D1 (de) 2003-06-02 2004-05-26 Pharmazeutische zusammensetzung auf basis von ketorolac oder einem seiner pharmazeutisch annehmbaren salze und verwendung von ketorolac oder seinen salzen in pharmazeutischen zusammensetzungen
US10/559,252 US7879901B2 (en) 2003-06-02 2004-05-26 Sublingual Formulations of Ketorolac or Salts Thereof
ES04734795T ES2344984T3 (es) 2003-06-02 2004-05-26 Composicion farmaceutica basada en ketorolaco o una de sus sales farmaceuticamente aceptables y uso del ketorolaco o sus sales en composiciones farmaceuticas.
EP04734795A EP1633342B1 (en) 2003-06-02 2004-05-26 Pharmaceutical composition based on ketorolac or one of its salts pharmaceutically acceptable and use of ketorolac or its salts in pharmaceutical compositions
AT04734795T ATE463243T1 (de) 2003-06-02 2004-05-26 Pharmazeutische zusammensetzung auf basis von ketorolac oder einem seiner pharmazeutisch annehmbaren salze und verwendung von ketorolac oder seinen salzen in pharmazeutischen zusammensetzungen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0302736A BRPI0302736B8 (pt) 2003-06-02 2003-06-02 composição farmacêutica a base de cetorolaco ou de um de seus sais farmaceuticamente aceitáveis para uso sublingual

Publications (3)

Publication Number Publication Date
BR0302736A BR0302736A (pt) 2005-05-10
BR0302736B1 BR0302736B1 (pt) 2014-07-29
BRPI0302736B8 true BRPI0302736B8 (pt) 2021-05-25

Family

ID=36584875

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0302736A BRPI0302736B8 (pt) 2003-06-02 2003-06-02 composição farmacêutica a base de cetorolaco ou de um de seus sais farmaceuticamente aceitáveis para uso sublingual

Country Status (7)

Country Link
US (1) US7879901B2 (pt)
EP (1) EP1633342B1 (pt)
AT (1) ATE463243T1 (pt)
BR (1) BRPI0302736B8 (pt)
DE (1) DE602004026437D1 (pt)
ES (1) ES2344984T3 (pt)
WO (1) WO2004105678A2 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007003948A (es) * 2007-04-02 2009-02-25 World Trade Imp Export Wtie Ag Composicion farmaceutica en forma de tableta sublingual que comprende un antiinflamatorio no esteroideo y un analgesico opiaceo para el manejo del dolor.
WO2008150887A1 (en) * 2007-05-29 2008-12-11 Livescribe, Inc. Self-addressing paper
MX2013008993A (es) 2013-08-02 2014-03-24 Raam De Sahuayo S A De C V Lab Sistema de liberacion modificada en tres fases de un antiinflamatorio no esteroide.
UA126916C2 (uk) * 2017-04-27 2023-02-22 Др. Редді'З Лабораторіз Лімітед Фармацевтична композиція кеторолаку
PE20260437A1 (es) * 2023-04-13 2026-02-19 Ache Laboratorios Farmaceuticos Sa Composicion farmaceutica oral, proceso para producir de granulos o una composicion farmaceutica oral, granulo farmaceutico oral, uso de la composicion farmaceutica y metodo para tratar afecciones inflamatorias, dolores y/o moderar el uso de opioides perioperatorios

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4089969A (en) 1976-07-14 1978-05-16 Syntex (U.S.A.) Inc. 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
US5288497A (en) * 1985-05-01 1994-02-22 The University Of Utah Compositions of oral dissolvable medicaments
JP3140050B2 (ja) 1990-03-16 2001-03-05 ザ、プロクター、エンド、ギャンブル、カンパニー 歯周病の治療に関するケトロラックの用法
AU653026B2 (en) * 1991-06-07 1994-09-15 Teikoku Seiyaku Kabushiki Kaisha Physiologically active polypeptide-containing pharmaceutical composition
DE69333009T2 (de) 1992-11-09 2003-12-04 Neurogesx, Inc. Transdermale verabreichung von ketorolac
US5626838A (en) 1995-03-13 1997-05-06 The Procter & Gamble Company Use of ketorolac for treatment of squamous cell carcinomas of the oral cavity or oropharynx
US5976566A (en) 1997-08-29 1999-11-02 Macrochem Corporation Non-steroidal antiinflammtory drug formulations for topical application to the skin
US6090368A (en) 1998-03-03 2000-07-18 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Pharmaceutical compositions for intranasal spray administration of ketorolac tromethamine
JP2004506680A (ja) * 2000-08-18 2004-03-04 ファルマシア・コーポレーション シクロオキシゲナーゼ−２阻害剤の迅速崩壊経口製剤
US6685951B2 (en) * 2001-07-05 2004-02-03 R. T. Alamo Ventures I, Inc. Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine
PL372290A1 (en) * 2002-02-07 2005-07-11 Pharmacia Corporation Pharmaceutical dosage form for mucosal delivery

Also Published As

Publication number Publication date
ES2344984T3 (es) 2010-09-13
DE602004026437D1 (de) 2010-05-20
EP1633342A2 (en) 2006-03-15
ATE463243T1 (de) 2010-04-15
WO2004105678A2 (en) 2004-12-09
EP1633342A4 (en) 2008-03-05
EP1633342B1 (en) 2010-04-07
BR0302736B1 (pt) 2014-07-29
BR0302736A (pt) 2005-05-10
US20060128782A1 (en) 2006-06-15
US7879901B2 (en) 2011-02-01
WO2004105678A3 (en) 2005-04-21

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B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]

Free format text: BASEADO NO ART. 216 1 DA LPI, APRESENTE COPIA AUTENTICADA DA PROCURACAO PARA QUE ESTA SEJA ACEITA.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
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Ipc: A61K 31/47 (2011.01), A61P 29/00 (2011.01), A61P 3

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
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