BRPI0307074A2 - meios sem soro para condrócitos e métodos para seu uso - Google Patents
meios sem soro para condrócitos e métodos para seu usoInfo
- Publication number
- BRPI0307074A2 BRPI0307074A2 BRPI0307074A BRPI0307074A BRPI0307074A2 BR PI0307074 A2 BRPI0307074 A2 BR PI0307074A2 BR PI0307074 A BRPI0307074 A BR PI0307074A BR PI0307074 A BRPI0307074 A BR PI0307074A BR PI0307074 A2 BRPI0307074 A2 BR PI0307074A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- serum free
- chondrocyte media
- media
- free chondrocyte
- Prior art date
Links
- 210000001612 chondrocyte Anatomy 0.000 title 1
- 210000002966 serum Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/135—Platelet-derived growth factor [PDGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/58—Adhesion molecules, e.g. ICAM, VCAM, CD18 (ligand), CD11 (ligand), CD49 (ligand)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35194902P | 2002-01-25 | 2002-01-25 | |
| US38907802P | 2002-06-14 | 2002-06-14 | |
| PCT/US2003/001941 WO2003064598A2 (en) | 2002-01-25 | 2003-01-24 | Serum-free media for chondrocytes and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0307074A2 true BRPI0307074A2 (pt) | 2017-06-20 |
Family
ID=27669045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0307074A BRPI0307074A2 (pt) | 2002-01-25 | 2003-01-24 | meios sem soro para condrócitos e métodos para seu uso |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7169610B2 (pt) |
| EP (1) | EP1478734A4 (pt) |
| JP (1) | JP2005515777A (pt) |
| AU (1) | AU2008264154A1 (pt) |
| BR (1) | BRPI0307074A2 (pt) |
| CA (1) | CA2473360A1 (pt) |
| WO (1) | WO2003064598A2 (pt) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2552229C (en) | 2003-12-26 | 2013-03-12 | Miho Furue | Basal medium for es cell culturing |
| US8889127B2 (en) | 2004-07-01 | 2014-11-18 | Icahn School Of Medicine At Mount Sinai | Targeted protein replacement for the treatment of lysosomal storage disorders |
| CN101014699B (zh) * | 2004-08-24 | 2010-05-26 | 富士软件株式会社 | 去分化型软骨细胞向软骨细胞的再分化用培养基 |
| US8697139B2 (en) | 2004-09-21 | 2014-04-15 | Frank M. Phillips | Method of intervertebral disc treatment using articular chondrocyte cells |
| US20090169523A1 (en) | 2005-06-13 | 2009-07-02 | Catherine Verfaillie | Hsc self-renewal |
| EP1945809B1 (en) * | 2005-08-16 | 2012-06-27 | The Children's Mercy Hospital | Quantification of microsphere suspension hybridization and uses thereof |
| EP1930413B1 (en) * | 2005-08-23 | 2011-01-12 | Oriental Yeast Co., Ltd. | Technique for culture of mesenchymal stem cell utilizing laminin-5 |
| CA2623106C (en) | 2005-09-19 | 2013-12-24 | Histogenics Corporation | Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof |
| EP1764117A1 (en) | 2005-09-20 | 2007-03-21 | Zimmer GmbH | Implant for the repair of a cartilage defect and method for manufacturing the implant |
| JP4385076B2 (ja) | 2006-01-13 | 2009-12-16 | 独立行政法人科学技術振興機構 | 動物細胞を無血清培養するための培地用添加剤、キット及びこれらの利用 |
| BRPI0713572A2 (pt) * | 2006-06-20 | 2012-10-23 | Stephen Duguay | meios livres de soro e seus usos para expansão de condrócitos |
| MX2009010694A (es) * | 2007-04-06 | 2009-10-22 | Genzyme Corp | Metodo para evaluar celulas y cultivos celulares. |
| KR101574989B1 (ko) * | 2007-12-28 | 2015-12-21 | 후지레비오 가부시키가이샤 | 포유 동물 체세포용 배지 및 이를 위한 첨가제 |
| WO2009092092A1 (en) | 2008-01-18 | 2009-07-23 | Regents Of The University Of Minnesota | Stem cell aggregates and methods for making and using |
| KR20170073614A (ko) * | 2008-03-21 | 2017-06-28 | 티슈진, 인코포레이티드 | 추간디스크 퇴행 치료용 조성물 |
| WO2010055616A1 (ja) * | 2008-11-11 | 2010-05-20 | 独立行政法人科学技術振興機構 | 分化誘導培地用添加剤およびその利用 |
| US11248211B2 (en) * | 2008-11-25 | 2022-02-15 | Kolon Tissuegene, Inc. | Primed cell therapy |
| US20110020292A1 (en) | 2009-07-21 | 2011-01-27 | Abt Holding Company | Use of Stem Cells to Reduce Leukocyte Extravasation |
| EP2456853B1 (en) | 2009-07-21 | 2020-10-28 | ABT Holding Company | Use of stem cells to reduce leukocyte extravasation |
| CA2791331A1 (en) | 2010-02-25 | 2011-09-01 | Abt Holding Company | Modulation of angiogenesis |
| SG183497A1 (en) | 2010-02-25 | 2012-09-27 | Abt Holding Co | Modulation of macrophage activation |
| JP5804385B2 (ja) | 2010-03-10 | 2015-11-04 | 株式会社ツーセル | 間葉系幹細胞を含む細胞製剤及びその製造方法 |
| DK2568991T6 (en) | 2010-05-12 | 2019-03-18 | Abt Holding Co | MODULATION OF SPLENOCYTES IN CELL THERAPY |
| WO2011158125A2 (en) | 2010-06-17 | 2011-12-22 | Katholieke Universiteit Leuven | Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the methods, and methods for using the cells |
| SG10201914007YA (en) | 2010-08-24 | 2020-03-30 | Univ Minnesota | Non-static suspension culture of cell aggregates |
| US8895291B2 (en) | 2010-10-08 | 2014-11-25 | Terumo Bct, Inc. | Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions |
| US9388388B2 (en) | 2011-01-31 | 2016-07-12 | Katholieke Universiteit Leuven | Methods for making cells with an extra-embryonic endodermal precursor phenotype |
| US9562252B2 (en) * | 2011-05-13 | 2017-02-07 | Biogen Ma Inc. | Methods of preventing and removing trisulfide bonds |
| WO2012168295A1 (en) | 2011-06-06 | 2012-12-13 | ReGenesys BVBA | Expansion of stem cells in hollow fiber bioreactors |
| WO2013019857A2 (en) | 2011-08-01 | 2013-02-07 | Alnylam Pharmaceuticals, Inc. | Method for improving the success rate of hematopoietic stem cell transplants |
| EP3741384A1 (en) | 2011-09-07 | 2020-11-25 | Mount Sinai School Of Medicine | Ceramidase and cell differentiation |
| GB201119335D0 (en) | 2011-11-09 | 2011-12-21 | Univ Leuven Kath | Hepatitis virus infectable stem cells |
| SG11201402108YA (en) | 2011-11-11 | 2014-06-27 | Essential Pharmaceuticals Llc | Kit comprising serum replacement and labile factors |
| CN109529028A (zh) | 2012-06-01 | 2019-03-29 | 西奈山伊坎医学院 | 在感染的治疗和预防中的神经酰胺水平 |
| EP2875125B1 (en) | 2012-07-20 | 2018-10-24 | Alfred C. Kuo | Methods for producing cartilage and bone |
| WO2014160390A1 (en) | 2013-03-14 | 2014-10-02 | Icahn School Of Medicine At Mount Sinai | Therapeutic acid ceramidase compositions and methods of making and using them |
| PT2983680T (pt) | 2013-04-12 | 2020-10-29 | Abt Holding Co | Melhoria de órgãos para transplante |
| ES2753323T3 (es) | 2013-04-30 | 2020-04-08 | Univ Leuven Kath | Terapia celular para síndromes mielodisplásicos |
| CA3135208A1 (en) * | 2013-06-11 | 2014-12-18 | Ncardia B.V. | Culture medium compositions for maturating cardiomyocytes derived from pluripotent mammalian stem cells |
| EP3009503B1 (en) * | 2013-06-12 | 2019-08-07 | Shiseido Company Ltd. | Serum-free medium containing pdgf for ds cells |
| JP6612227B2 (ja) | 2013-11-16 | 2019-11-27 | テルモ ビーシーティー、インコーポレーテッド | バイオリアクターにおける細胞増殖 |
| SG11201604994UA (en) | 2013-12-20 | 2016-07-28 | Essential Pharmaceuticals Llc | Media for cell culture |
| US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
| JP6780638B2 (ja) * | 2015-03-30 | 2020-11-04 | 味の素株式会社 | ヒト血清アルブミンを含む神経幹細胞増殖培地 |
| US10967006B2 (en) | 2016-01-21 | 2021-04-06 | Abt Holding Company | Stem cells for wound healing |
| US11590175B2 (en) | 2017-08-23 | 2023-02-28 | Merakris Therapeutics Llc | Compositions containing amniotic components and methods for preparation and use thereof |
| SG11202003354VA (en) | 2017-10-13 | 2020-05-28 | Boehringer Ingelheim Int | Perfusion medium |
| US11857576B2 (en) * | 2017-12-07 | 2024-01-02 | Vericel Corporation | Compositions and methods for repairing cartilage defects |
| CN109136170B (zh) * | 2018-08-20 | 2022-02-18 | 东北农业大学 | 一种适用于鲤鱼三倍体细胞生长的无血清培养基及其应用 |
| WO2020176801A1 (en) | 2019-02-28 | 2020-09-03 | Fagg William Samuel Iv | Amniotic fluid-derived extracellular vesicles and uses thereof for wound healing |
| CN113061578B (zh) * | 2021-04-23 | 2023-04-21 | 苏州依科赛生物科技股份有限公司 | 一种用于细胞培养基的脂质混合物及其配制方法与应用 |
| US12226438B2 (en) * | 2021-06-18 | 2025-02-18 | Hilltop BioSciences, Inc. | System and method for therapeutic compositions from a plurality of different birth tissues and exosomes |
| JP2025507959A (ja) | 2022-03-04 | 2025-03-21 | ヴェリセル コーポレイション | 軟骨の欠損を修復するための方法及びデバイス |
| JPWO2025018336A1 (pt) * | 2023-07-20 | 2025-01-23 | ||
| WO2025037108A2 (en) | 2023-08-15 | 2025-02-20 | Board Of Trustees Of The Leland Stanford Junior University | Modified thrombopoietin |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5904717A (en) * | 1986-01-28 | 1999-05-18 | Thm Biomedical, Inc. | Method and device for reconstruction of articular cartilage |
| US5405772A (en) * | 1993-06-18 | 1995-04-11 | Amgen Inc. | Medium for long-term proliferation and development of cells |
| US5871779A (en) * | 1994-01-18 | 1999-02-16 | Mount Sinai Hospital Corporation | Treatment of arthropathies with vanadate compounds or analogues thereof |
| US5723331A (en) * | 1994-05-05 | 1998-03-03 | Genzyme Corporation | Methods and compositions for the repair of articular cartilage defects in mammals |
| US5908782A (en) * | 1995-06-05 | 1999-06-01 | Osiris Therapeutics, Inc. | Chemically defined medium for human mesenchymal stem cells |
| JP2000507812A (ja) * | 1996-03-12 | 2000-06-27 | ライフ テクノロジーズ，インコーポレイテッド | 造血細胞培養栄養補充成分 |
| EP0920490A2 (en) * | 1996-07-25 | 1999-06-09 | Genzyme Corporation | Chondrocyte media formulations and culture procedures |
| US6001352A (en) * | 1997-03-31 | 1999-12-14 | Osteobiologics, Inc. | Resurfacing cartilage defects with chondrocytes proliferated without differentiation using platelet-derived growth factor |
| WO1998059035A2 (en) * | 1997-06-25 | 1998-12-30 | The Goverment Of The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services, National Institutes Of Health | Serum-free cell growth medium |
| US6153582A (en) * | 1998-11-05 | 2000-11-28 | Bausch & Lomb Surgical, Inc. | Defined serumfree medical solution for ophthalmology |
| JP2002529071A (ja) | 1998-11-09 | 2002-09-10 | コンソルツィオ・ペール・ラ・ジェスティオーネ・デル・チェントロ・ディ・ビオテクノロジー・アヴァンツァテ | 軟骨細胞様細胞のための無血清培地 |
| US6429013B1 (en) * | 1999-08-19 | 2002-08-06 | Artecel Science, Inc. | Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair |
| FR2798671A1 (fr) | 1999-09-16 | 2001-03-23 | Univ Paris Curie | Compositions de chondrocytes, preparation et utilisations |
| WO2001057083A1 (en) | 2000-02-04 | 2001-08-09 | Zymogenetics, Inc. | Methods for promoting growth of bone, ligament, and cartilage using zvegf4 |
| US20020041900A1 (en) * | 2000-05-01 | 2002-04-11 | Ole Olsen | Chondrocyte cultures and fractions therefrom |
-
2003
- 2003-01-24 BR BRPI0307074A patent/BRPI0307074A2/pt not_active IP Right Cessation
- 2003-01-24 WO PCT/US2003/001941 patent/WO2003064598A2/en not_active Ceased
- 2003-01-24 CA CA002473360A patent/CA2473360A1/en not_active Abandoned
- 2003-01-24 JP JP2003564194A patent/JP2005515777A/ja active Pending
- 2003-01-24 US US10/350,816 patent/US7169610B2/en not_active Expired - Fee Related
- 2003-01-24 EP EP03703966A patent/EP1478734A4/en not_active Withdrawn
-
2007
- 2007-01-22 US US11/625,720 patent/US20070275463A1/en not_active Abandoned
-
2008
- 2008-12-23 AU AU2008264154A patent/AU2008264154A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20030211604A1 (en) | 2003-11-13 |
| WO2003064598A3 (en) | 2003-10-16 |
| EP1478734A2 (en) | 2004-11-24 |
| JP2005515777A (ja) | 2005-06-02 |
| US20070275463A1 (en) | 2007-11-29 |
| EP1478734A4 (en) | 2006-04-05 |
| US7169610B2 (en) | 2007-01-30 |
| CA2473360A1 (en) | 2003-08-07 |
| WO2003064598A2 (en) | 2003-08-07 |
| AU2008264154A1 (en) | 2009-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06H | Technical and formal requirements: requirement cancelled [chapter 6.8 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |