BRPI0312331A2 - composições de ácido hialurônico e métodos de emprego. - Google Patents
composições de ácido hialurônico e métodos de emprego.Info
- Publication number
- BRPI0312331A2 BRPI0312331A2 BRPI0312331A BR0312331A BRPI0312331A2 BR PI0312331 A2 BRPI0312331 A2 BR PI0312331A2 BR PI0312331 A BRPI0312331 A BR PI0312331A BR 0312331 A BR0312331 A BR 0312331A BR PI0312331 A2 BRPI0312331 A2 BR PI0312331A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- hyaluronic acid
- acid compositions
- compositions
- hyaluronic
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title 1
- 229920002674 hyaluronan Polymers 0.000 title 1
- 229960003160 hyaluronic acid Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
- A61K49/0043—Fluorescein, used in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0054—Macromolecular compounds, i.e. oligomers, polymers, dendrimers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Eyeglasses (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39395402P | 2002-07-03 | 2002-07-03 | |
| PCT/US2003/021034 WO2004004744A1 (en) | 2002-07-03 | 2003-07-03 | Compositions of hyaluronic acid and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0312331A2 true BRPI0312331A2 (pt) | 2016-06-28 |
Family
ID=30115663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0312331A BRPI0312331A2 (pt) | 2002-07-03 | 2003-07-03 | composições de ácido hialurônico e métodos de emprego. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20060094643A1 (pt) |
| EP (1) | EP1539193A4 (pt) |
| JP (2) | JP4818608B2 (pt) |
| CN (3) | CN1671400A (pt) |
| AU (1) | AU2003256381A1 (pt) |
| BR (1) | BRPI0312331A2 (pt) |
| CA (1) | CA2491054A1 (pt) |
| IL (1) | IL165910A0 (pt) |
| MX (1) | MXPA05000186A (pt) |
| NZ (1) | NZ537735A (pt) |
| RU (1) | RU2005102604A (pt) |
| WO (1) | WO2004004744A1 (pt) |
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7722808B2 (en) | 2003-09-12 | 2010-05-25 | Novartis Ag | Method and kits for sterilizing and storing soft contact lenses |
| JP2005200386A (ja) * | 2004-01-19 | 2005-07-28 | Chisso Corp | リパーゼ阻害効果、脂肪吸収抑制効果及びコレステロール吸収抑制効果を有する薬剤 |
| US20060083732A1 (en) * | 2004-06-30 | 2006-04-20 | Arlene Gwon | Hyaluronic acid in the enhancement of lens regeneration |
| US8802651B2 (en) * | 2004-06-30 | 2014-08-12 | Abbott Medical Optics Inc. | Hyaluronic acid in the enhancement of lens regeneration |
| US7794697B2 (en) * | 2004-06-30 | 2010-09-14 | Abbott Medical Optics Inc. | Enhancement of lens regeneration using materials comprising polysiloxane polymers |
| US20080075756A1 (en) * | 2004-06-30 | 2008-03-27 | Advanced Medical Optics, Inc. | Enhancement of lens regeneration using materials comprising polymers |
| FR2873379B1 (fr) * | 2004-07-23 | 2008-05-16 | Jerome Asius | Procede de preparation d'acide hyaluronique reticule, acide hyaluronique reticule susceptible d'etre obtenu par ledit procede, implant contenant ledit acide hyaluronique reticule, et son utilisation |
| JP4845359B2 (ja) * | 2004-09-16 | 2011-12-28 | 弘 竹田 | 口腔ケア用組成物 |
| EP1861069B2 (en) * | 2005-02-09 | 2013-07-03 | Safilens S.R.L. | Contact lens, method for producing same, and pack for storage and maintenance of a contact lens |
| ITMI20052036A1 (it) * | 2005-10-26 | 2007-04-27 | Professional Dietetics Srl | Composizioni farmaceutiche oftalmiche a base di amminoacidi e sodio ialuronato |
| CN101432311A (zh) * | 2006-02-28 | 2009-05-13 | 诺维信生物聚合物公司 | 透明质酸衍生物 |
| ITPD20060219A1 (it) * | 2006-05-31 | 2007-12-01 | Fidia Farmaceutici | Composizioni farmaceutiche contenenti acido ialuronico solfatato nel trattamento dell'osteoartrosi |
| JP2007320906A (ja) * | 2006-06-01 | 2007-12-13 | Shiseido Co Ltd | 小じわ改善剤 |
| JP2008063334A (ja) * | 2006-08-10 | 2008-03-21 | Lion Corp | 水溶性有効成分の付着化組成物及び水溶性有効成分の付着方法 |
| US9579341B2 (en) | 2007-05-16 | 2017-02-28 | Johnson & Johnson Consumer Inc. | Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods |
| US8609634B2 (en) | 2007-05-16 | 2013-12-17 | Mcneil-Ppc, Inc. | Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods |
| US10092524B2 (en) | 2008-06-11 | 2018-10-09 | Edge Therapeutics, Inc. | Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage |
| US20090036404A1 (en) * | 2007-08-02 | 2009-02-05 | Macleod Steven K | Ophthalmic compositions comprising a carboxyl-modified fructan or a salt thereof |
| EP2188655B1 (en) | 2007-08-31 | 2012-01-04 | Novartis AG | Contact lens packaging solutions |
| TWI419719B (zh) | 2007-08-31 | 2013-12-21 | Novartis Ag | 隱形眼鏡產物 |
| US20090068122A1 (en) * | 2007-09-06 | 2009-03-12 | Shira Pilch | Dentifrice Compositions for Treating Xerostomia |
| AR070355A1 (es) | 2008-02-08 | 2010-03-31 | Colgate Palmolive Co | Composiciones, metodos para el tratamiento de la xerostomia y uso |
| US20100075420A1 (en) * | 2008-03-14 | 2010-03-25 | Anita Saraf | Novel Gene Delivery Vectors for Human Mesenchymal Stem Cells |
| CN102046661A (zh) | 2008-03-28 | 2011-05-04 | 加利福尼亚大学董事会 | 多肽-聚合物偶联物和其使用方法 |
| JP5758797B2 (ja) | 2008-04-04 | 2015-08-05 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション | アルキル化半合成グリコサミノグリカンエーテルならびにその製造および使用方法 |
| US20100022471A1 (en) * | 2008-07-23 | 2010-01-28 | Sage Products Inc. | Oral Moisturizer for Alleviating Dry Mouth |
| EP3246048B1 (en) | 2009-02-18 | 2024-04-03 | Calm Water Therapeutics LLC | Bi-functional co-polymer use for ophthalmic applications |
| WO2010099543A2 (en) * | 2009-02-27 | 2010-09-02 | Inter-Med, Inc. | Compositions and methods for detecting oral neoplasm |
| IT1397246B1 (it) * | 2009-05-14 | 2013-01-04 | Fidia Farmaceutici | Nuovi medicamenti ad uso topico a base di acido ialuronico solfatato come agente attivante o inibente l'attivita' citochinica |
| JP5601805B2 (ja) * | 2009-08-24 | 2014-10-08 | キユーピー株式会社 | 経口用ドライアイ改善剤、ならびに前記経口用ドライアイ改善剤を含む食品組成物および医薬品組成物 |
| CN106913874A (zh) * | 2010-02-22 | 2017-07-04 | 优势医疗公司 | 治疗脑的出血性病状的方法和组合物 |
| US20110212196A1 (en) * | 2010-03-01 | 2011-09-01 | Maine Conservation Medicine Center | Therapeutic oil composition containing carvone |
| ITUD20100112A1 (it) * | 2010-06-09 | 2011-12-10 | Farma Derma S R L | Preparazione per uso vaginale e rettale e relativo procedimento di produzione |
| US9522162B2 (en) | 2011-03-23 | 2016-12-20 | University Of Utah Research Foundation | Methods for treating or preventing urological inflammation |
| SG10201602665UA (en) | 2011-04-05 | 2016-05-30 | Edge Therapeutics | Intraventricular Drug Delivery System For Improving Outcome After A Brain Injury Affecting Cerebral Blood Flow |
| US20130108550A1 (en) * | 2011-10-26 | 2013-05-02 | Abbott Cardiovasculr Systems, Inc. | Bioabsorbable Co-Filler for Cerebrovascular Aneurysms |
| JP5840107B2 (ja) * | 2012-06-17 | 2016-01-06 | コスメディ製薬株式会社 | ヒアルロン酸ゲル及びその製造方法 |
| KR101498510B1 (ko) * | 2012-06-26 | 2015-03-04 | 서울대학교산학협력단 | 히알루론산을 포함하는 인공 타액 조성물 |
| JP2015533792A (ja) * | 2012-09-05 | 2015-11-26 | シレンティス・エセ・ア・ウ | ｓｉＲＮＡならびに眼の状態の処置および／または予防のための方法および組成物におけるその使用 |
| US20140178327A1 (en) * | 2012-12-21 | 2014-06-26 | Coopervision International Holding Company, Lp | Antimicrobial Ophthalmic Devices |
| EP4137139A1 (en) | 2013-07-10 | 2023-02-22 | Matrix Biology Institute | Compositions of hyaluronan with high elasticity and uses thereof |
| US20160175457A1 (en) * | 2013-09-12 | 2016-06-23 | Dsm Ip Assets B.V. | Ocular device |
| RU2551312C1 (ru) * | 2014-04-24 | 2015-05-20 | Людмила Владимировна Уварова | Способ восстановления тканей зубочелюстной системы |
| US10695290B2 (en) * | 2014-05-19 | 2020-06-30 | A. Ebbie Soroudi, M.D., M.S., A Professional Medical Corporation | Non-irritating, non-blurring, photostable ophthalmic sunscreen composition |
| ES2897733T3 (es) * | 2014-06-15 | 2022-03-02 | Yeda Res & Dev | Tratamiento de superficies de lentes de contacto y tratamiento de molestias oculares mediante polímeros solubles en agua y lípidos/liposomas |
| JP6457281B2 (ja) * | 2015-01-29 | 2019-01-23 | 学校法人東京電機大学 | 修飾ヒアルロン酸及び／又はその塩、並びにその製造方法 |
| US20160279108A1 (en) * | 2015-02-24 | 2016-09-29 | University Of Kansas | Targeted mtor inhibitors |
| US20180185276A1 (en) * | 2015-03-26 | 2018-07-05 | Mitotech S.A. | Contact lenses carrying mitochonrially-targeted antioxidants |
| EP3108874A1 (en) * | 2015-06-26 | 2016-12-28 | TRB Chemedica AG | Ophthalmologic pharmaceutical composition |
| WO2017053339A1 (en) | 2015-09-24 | 2017-03-30 | Matrix Biology Institute | High elasticity hyaluronan compositions and methods of use thereof |
| MY186090A (en) | 2015-12-03 | 2021-06-21 | Alcon Inc | Contact lens packaging solutions |
| EP3386520B1 (en) * | 2015-12-09 | 2022-07-20 | The Regents of The University of California | Methods of treating an ocular disease or disorder |
| DE102016204472A1 (de) * | 2016-03-17 | 2017-09-21 | Ursapharm Arzneimittel Gmbh | Kit zur kosmetischen Behandlung des Auges und der Haut und Kosmetikum zur Anwendung am Auge und auf der Haut |
| EP3479830B1 (en) * | 2016-04-25 | 2024-09-11 | College of Animal Science & Technology, Qingdao Agriculture University | Application of small-molecule hyaluronic acid fragment |
| EP3241895A1 (en) * | 2016-05-04 | 2017-11-08 | ETH Zürich, ETH Transfer | Transglutaminase mediated high molecular weight hyaluronan hydrogels |
| AU2016413933B2 (en) | 2016-07-06 | 2023-06-15 | Calm Water Therapeutics Llc | Bi-functional co-polymer use for ophthalmic and other topical and local applications |
| IT201600079633A1 (it) * | 2016-07-28 | 2018-01-28 | Fidia Farm Spa | Procedimento di preparazione e purificazione del sale sodico dell’acido ialuronico |
| US11337994B2 (en) | 2016-09-15 | 2022-05-24 | University Of Utah Research Foundation | In situ gelling compositions for the treatment or prevention of inflammation and tissue damage |
| EP3525799B1 (en) * | 2016-10-14 | 2022-01-26 | i.com Medical GmbH | Method for establishing, restoring, and preserving homeostasis of the ocular surface |
| JP6338715B2 (ja) * | 2017-02-06 | 2018-06-06 | ナンヤン テクノロジカル ユニヴァーシティー | 眼用及び医療用の重合性組成物及びそれを重合して得られる抗菌性組成物 |
| WO2019022493A1 (ko) * | 2017-07-26 | 2019-01-31 | (주)유레 | 히알루론산-칼슘 및 폴리라이신을 포함하는 창상 피복재 및 그 제조 방법 |
| US11129862B2 (en) | 2017-08-30 | 2021-09-28 | Johnson & Johnson Consumer Inc. | Ophthalmic compositions |
| WO2020057606A1 (en) * | 2018-09-20 | 2020-03-26 | The Hong Kong University Of Science And Technology | Eyedrop compositions |
| WO2020057548A1 (en) * | 2018-09-20 | 2020-03-26 | The Hong Kong University Of Science And Technology | Eyedrop compositions |
| CN111228653A (zh) | 2018-11-13 | 2020-06-05 | 格莱科米拉治疗公司 | 用电离辐射加强癌症治疗的方法 |
| EP3893887A4 (en) * | 2018-12-13 | 2023-01-04 | Eyenos, Inc. | LXR AGONIST IN TOPICAL OPHTHALMIC FORMULATION FOR THE TREATMENT OF DRY EYE |
| US12453628B2 (en) * | 2019-05-07 | 2025-10-28 | Cornell University | Temporary synthetic carrier for corneal tissue insertion and tissue delivery |
| CN112494710B (zh) * | 2019-09-16 | 2021-12-14 | 天津大学 | 一种转谷氨酰胺酶促交联的双网络粘合剂及其制备方法 |
| RU2716023C1 (ru) * | 2019-09-20 | 2020-03-05 | Акционерное Общество "Свобода" (Ао "Свобода") | Активный комплекс для приготовления композиций по уходу за полостью рта |
| WO2021167845A1 (en) | 2020-02-18 | 2021-08-26 | Sunstar Americas, Inc. | Oral care composition |
| KR102479119B1 (ko) * | 2020-10-07 | 2022-12-19 | 주식회사 휴메디솔 | 생체적합성 mpc 고분자 기반의 콘택트렌즈 다기능 용액 및 이의 제조방법 |
| US20230263901A1 (en) * | 2021-01-29 | 2023-08-24 | Yimin Sun | Mucus adhesion drug delivery |
| KR20230156763A (ko) * | 2021-03-11 | 2023-11-14 | 보오슈 + 롬 아일랜드 리미티드 | 포장 용액 |
| CN115317505A (zh) * | 2021-05-10 | 2022-11-11 | 傅毓秀 | 玻尿酸用于制备治疗肺纤维化药剂的用途 |
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| TWI815436B (zh) * | 2022-05-10 | 2023-09-11 | 長庚大學 | 使用聚離胺酸奈米粒子來治療乾眼症 |
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-
2003
- 2003-07-03 EP EP03763195A patent/EP1539193A4/en not_active Withdrawn
- 2003-07-03 IL IL16591003A patent/IL165910A0/xx unknown
- 2003-07-03 MX MXPA05000186A patent/MXPA05000186A/es unknown
- 2003-07-03 CN CNA038177811A patent/CN1671400A/zh active Pending
- 2003-07-03 CN CN201310303034.3A patent/CN103638040A/zh active Pending
- 2003-07-03 US US10/519,329 patent/US20060094643A1/en not_active Abandoned
- 2003-07-03 AU AU2003256381A patent/AU2003256381A1/en not_active Abandoned
- 2003-07-03 WO PCT/US2003/021034 patent/WO2004004744A1/en not_active Ceased
- 2003-07-03 RU RU2005102604/15A patent/RU2005102604A/ru not_active Application Discontinuation
- 2003-07-03 BR BRPI0312331A patent/BRPI0312331A2/pt not_active IP Right Cessation
- 2003-07-03 NZ NZ537735A patent/NZ537735A/en not_active IP Right Cessation
- 2003-07-03 CA CA002491054A patent/CA2491054A1/en not_active Abandoned
- 2003-07-03 CN CN2011100712765A patent/CN102178692A/zh active Pending
- 2003-07-03 JP JP2004519871A patent/JP4818608B2/ja not_active Expired - Fee Related
-
2010
- 2010-07-05 JP JP2010153446A patent/JP2010270126A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2491054A1 (en) | 2004-01-15 |
| NZ537735A (en) | 2006-08-31 |
| EP1539193A1 (en) | 2005-06-15 |
| JP2006502988A (ja) | 2006-01-26 |
| MXPA05000186A (es) | 2005-08-17 |
| AU2003256381A1 (en) | 2004-01-23 |
| EP1539193A4 (en) | 2010-05-05 |
| CN103638040A (zh) | 2014-03-19 |
| JP4818608B2 (ja) | 2011-11-16 |
| IL165910A0 (en) | 2006-01-15 |
| CN1671400A (zh) | 2005-09-21 |
| US20060094643A1 (en) | 2006-05-04 |
| JP2010270126A (ja) | 2010-12-02 |
| CN102178692A (zh) | 2011-09-14 |
| RU2005102604A (ru) | 2005-09-10 |
| WO2004004744A1 (en) | 2004-01-15 |
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