BRPI0406499A - Insulina de longa atuação para redução da morbidez e mortalidade cardiovascular em pacientes pré-diabéticos e pacientes com diabetes tipo 2 - Google Patents

Insulina de longa atuação para redução da morbidez e mortalidade cardiovascular em pacientes pré-diabéticos e pacientes com diabetes tipo 2

Info

Publication number
BRPI0406499A
BRPI0406499A BR0406499-2A BRPI0406499A BRPI0406499A BR PI0406499 A BRPI0406499 A BR PI0406499A BR PI0406499 A BRPI0406499 A BR PI0406499A BR PI0406499 A BRPI0406499 A BR PI0406499A
Authority
BR
Brazil
Prior art keywords
patients
type
mortality
diabetes
long
Prior art date
Application number
BR0406499-2A
Other languages
English (en)
Inventor
Ralf Rosskamp
Hertzel Gerstein
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of BRPI0406499A publication Critical patent/BRPI0406499A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"INSULINA DE LONGA ATUAçãO PARA REDUçãO DA MORBIDEZ E MORTALIDADE CARDIOVASCULAR EM PACIENTES PRé-DIABéTICOS E PACIENTES COM DIABETES TIPO 2". A presente invenção refere-se a um método para redução da morbidez e mortalidade cardiovascular em uma população de paciente de Diabetes Tipo 2 ou pré-diabética. O método compreende administrar uma dosagem eficaz de uma insulina de longa atuação, preferivelmente, insulina glargina, a um paciente de Diabetes Tipo 2 ou pré-diabético.
BR0406499-2A 2003-01-14 2004-01-14 Insulina de longa atuação para redução da morbidez e mortalidade cardiovascular em pacientes pré-diabéticos e pacientes com diabetes tipo 2 BRPI0406499A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43994103P 2003-01-14 2003-01-14
PCT/US2004/000879 WO2004064862A1 (en) 2003-01-14 2004-01-14 Long acting insulin for reducing cardiovascular morbidity and mortality in prediabetic patients and patients with type 2 diabetes

Publications (1)

Publication Number Publication Date
BRPI0406499A true BRPI0406499A (pt) 2005-12-06

Family

ID=23746761

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0406499-2A BRPI0406499A (pt) 2003-01-14 2004-01-14 Insulina de longa atuação para redução da morbidez e mortalidade cardiovascular em pacientes pré-diabéticos e pacientes com diabetes tipo 2

Country Status (16)

Country Link
US (4) US7405196B2 (pt)
EP (2) EP2596800B1 (pt)
JP (1) JP5389325B2 (pt)
AU (2) AU2004206829B2 (pt)
BR (1) BRPI0406499A (pt)
CA (1) CA2512820C (pt)
CY (1) CY1118738T1 (pt)
DK (1) DK2596800T3 (pt)
ES (1) ES2604359T3 (pt)
GB (1) GB0309154D0 (pt)
HU (1) HUE031892T2 (pt)
IL (3) IL169697A (pt)
MX (1) MXPA05007470A (pt)
PT (1) PT2596800T (pt)
SI (1) SI2596800T1 (pt)
WO (1) WO2004064862A1 (pt)

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PL2498801T3 (pl) 2009-11-13 2018-08-31 Sanofi Aventis Deutschland Kompozycja farmaceutyczna zawierająca desPro<sup>36</sup>eksendyno-4(1-39)-Lys6-NH2 i metioninę
SI2498802T1 (sl) 2009-11-13 2015-05-29 Sanofi-Aventis Deutschland Gmbh Farmacevtski sestavek, ki vsebuje agonist GLP-1, inzulin in metionin
AU2011202239C1 (en) * 2010-05-19 2017-03-16 Sanofi Long-acting formulations of insulins
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MX359281B (es) 2010-06-21 2018-09-21 Mannkind Corp Sistema y metodos para suministrar un farmaco en polvo seco.
BR112013004756B1 (pt) 2010-08-30 2020-04-28 Sanofi Aventis Deutschland uso de ave0010 para a fabricação de um medicamento para o tratamento da diabetes melito tipo 2
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Also Published As

Publication number Publication date
IL208525A0 (en) 2010-12-30
US7405196B2 (en) 2008-07-29
US7977310B2 (en) 2011-07-12
JP2006515625A (ja) 2006-06-01
IL169697A (en) 2011-06-30
US20130012433A1 (en) 2013-01-10
CA2512820C (en) 2013-06-04
IL197739A (en) 2017-02-28
AU2010202738B2 (en) 2013-12-05
JP5389325B2 (ja) 2014-01-15
EP1589991A1 (en) 2005-11-02
US8809270B2 (en) 2014-08-19
EP2596800A1 (en) 2013-05-29
PT2596800T (pt) 2016-12-02
US20080287343A1 (en) 2008-11-20
SI2596800T1 (sl) 2017-04-26
IL169697A0 (en) 2007-07-04
GB0309154D0 (en) 2003-05-28
US20040229774A1 (en) 2004-11-18
AU2004206829A1 (en) 2004-08-05
DK2596800T3 (en) 2016-12-12
WO2004064862A1 (en) 2004-08-05
MXPA05007470A (es) 2005-09-21
CA2512820A1 (en) 2004-08-05
ES2604359T3 (es) 2017-03-06
CY1118738T1 (el) 2017-07-12
IL197739A0 (en) 2011-08-01
HUE031892T2 (en) 2017-08-28
US20110281793A1 (en) 2011-11-17
AU2004206829B2 (en) 2010-04-08
EP2596800B1 (en) 2016-08-24
AU2010202738A1 (en) 2010-07-22

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Legal Events

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B25G Requested change of headquarter approved

Owner name: AVENTIS PHARMACEUTICALS, INC. (US)

Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020070165509/RJ DE 23/11/2007.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]