BRPI0406592A - Usos de n-desmetilclozapina, métodos para o tratamento de psicose, de distúrbios afetivos, de demência, de dor neuropática e de glaucoma e composição farmacêutica - Google Patents

Usos de n-desmetilclozapina, métodos para o tratamento de psicose, de distúrbios afetivos, de demência, de dor neuropática e de glaucoma e composição farmacêutica

Info

Publication number
BRPI0406592A
BRPI0406592A BR0406592-1A BRPI0406592A BRPI0406592A BR PI0406592 A BRPI0406592 A BR PI0406592A BR PI0406592 A BRPI0406592 A BR PI0406592A BR PI0406592 A BRPI0406592 A BR PI0406592A
Authority
BR
Brazil
Prior art keywords
glaucoma
dementia
neuropathic pain
desmethylclozapine
methods
Prior art date
Application number
BR0406592-1A
Other languages
English (en)
Inventor
David M Weiner
Mark R Brann
Original Assignee
Acadia Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acadia Pharm Inc filed Critical Acadia Pharm Inc
Publication of BRPI0406592A publication Critical patent/BRPI0406592A/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"USOS DE N-DESMETILCLOZAPINA, MéTODOS PARA O TRATAMENTO DE PSICOSE, DE DISTúRBIOS AFETIVOS, DE DEMêNCIA, DE DOR NEUROPáTICA E DE GLAUCOMA E COMPOSIçãO FARMACêUTICA". Trata-se de um método para o tratamento de doenças neuropsiquiátricas incluindo a psicose, distúrbios afetivos, demência, dor neuropática e glaucoma. O tratamento é levado a efeito ao se administrar uma quantidade terapeuticamente eficaz de N-desmetilclozapina a um paciente que sofre de uma doença neuropsiquiátrica.
BR0406592-1A 2003-01-23 2004-01-21 Usos de n-desmetilclozapina, métodos para o tratamento de psicose, de distúrbios afetivos, de demência, de dor neuropática e de glaucoma e composição farmacêutica BRPI0406592A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44269003P 2003-01-23 2003-01-23
PCT/US2004/001509 WO2004064753A2 (en) 2003-01-23 2004-01-21 Use of n-desmethylclozapine to treat human neuropsychiatric disease

Publications (1)

Publication Number Publication Date
BRPI0406592A true BRPI0406592A (pt) 2005-12-20

Family

ID=32772052

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0406592-1A BRPI0406592A (pt) 2003-01-23 2004-01-21 Usos de n-desmetilclozapina, métodos para o tratamento de psicose, de distúrbios afetivos, de demência, de dor neuropática e de glaucoma e composição farmacêutica

Country Status (14)

Country Link
US (2) US20040224942A1 (pt)
EP (2) EP1994932A1 (pt)
JP (1) JP2006515628A (pt)
KR (1) KR20050092123A (pt)
CN (1) CN1741803A (pt)
AU (1) AU2004206931A1 (pt)
BR (1) BRPI0406592A (pt)
CA (1) CA2512043A1 (pt)
MX (1) MXPA05007784A (pt)
NZ (1) NZ541014A (pt)
RU (2) RU2336879C2 (pt)
SG (1) SG159390A1 (pt)
WO (1) WO2004064753A2 (pt)
ZA (1) ZA200505878B (pt)

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RU2005126614A (ru) 2006-01-27
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EP1589974A2 (en) 2005-11-02
MXPA05007784A (es) 2005-09-30
US20040224942A1 (en) 2004-11-11
ZA200505878B (en) 2006-04-26
WO2004064753A2 (en) 2004-08-05
CA2512043A1 (en) 2004-08-05
RU2008116931A (ru) 2009-11-10
CN1741803A (zh) 2006-03-01
NZ541014A (en) 2008-05-30
EP1994932A1 (en) 2008-11-26
SG159390A1 (en) 2010-03-30
RU2336879C2 (ru) 2008-10-27
US20090018119A1 (en) 2009-01-15
WO2004064753A3 (en) 2004-11-25
KR20050092123A (ko) 2005-09-20

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