BRPI0514199A - método de efetuar profilaxia ou tratar uma doença, composição farmacêutica, anticorpo monoclonal, célula de hibridoma, e, método de triar um agente, de humanizar anticorpo monoclonal 8a5 ou anticorpo monoclonal 6h7 e de produzir uma forma quimérica de anticorpo monoclonal 8a5 ou anticorpo monoclonal 6h7 - Google Patents

método de efetuar profilaxia ou tratar uma doença, composição farmacêutica, anticorpo monoclonal, célula de hibridoma, e, método de triar um agente, de humanizar anticorpo monoclonal 8a5 ou anticorpo monoclonal 6h7 e de produzir uma forma quimérica de anticorpo monoclonal 8a5 ou anticorpo monoclonal 6h7

Info

Publication number
BRPI0514199A
BRPI0514199A BRPI0514199-0A BRPI0514199A BRPI0514199A BR PI0514199 A BRPI0514199 A BR PI0514199A BR PI0514199 A BRPI0514199 A BR PI0514199A BR PI0514199 A BRPI0514199 A BR PI0514199A
Authority
BR
Brazil
Prior art keywords
monoclonal antibody
disease
treating
pharmaceutical composition
agent
Prior art date
Application number
BRPI0514199-0A
Other languages
English (en)
Inventor
Dale B Schenk
Eliezer Masliah
Manuel J Buttini
Tamie J Chilcote
Edward Rockenstein
Kate Dora Games
Original Assignee
Elan Pharm Inc
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35908081&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0514199(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US10/915,214 external-priority patent/US8697082B2/en
Application filed by Elan Pharm Inc, Univ California filed Critical Elan Pharm Inc
Publication of BRPI0514199A publication Critical patent/BRPI0514199A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Psychology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

MéTODO DE EFETUAR PROFILAXIA OU TRATAR UMA DOENçA COMPOSIçãO FARMACêUTICA, ANTICORPO MONOCLONAL,CéLULA DE HIBRIDOMA, E, MéTODOS DE TRIAR UM AGENTE, DE HUMANIZAR ANTICORPO MONOCLONAL 8A5 OU ANTICORPO MONOCLONAL 6H7 E UM DE PRODUZIR UMA FORMA QUIMéRICA DE ANTICORPO MONOCLONAL 8A5 OU ANTICORPO MONOCLONAL 6H7 A invenção provê métodos e agentes melhorados para o tratamento de doenças associadas com doenças sinucleinopáticas, incluindo corpos de Lewy e alfa-sinucleína no cérebro de um paciente. Tais métodos englobam administrar agentes que induzam uma resposta imunogênica benéfica contra corpos de Lewy. Os métodos são particularmente úteis para tratamento profilático e terapêutico de mal de Parkinson.
BRPI0514199-0A 2004-08-09 2005-08-09 método de efetuar profilaxia ou tratar uma doença, composição farmacêutica, anticorpo monoclonal, célula de hibridoma, e, método de triar um agente, de humanizar anticorpo monoclonal 8a5 ou anticorpo monoclonal 6h7 e de produzir uma forma quimérica de anticorpo monoclonal 8a5 ou anticorpo monoclonal 6h7 BRPI0514199A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/915,214 US8697082B2 (en) 2002-11-01 2004-08-09 Prevention and treatment of synucleinopathic and amyloidogenic disease
US11/185,907 US8506959B2 (en) 2002-11-01 2005-07-19 Prevention and treatment of synucleinopathic and amyloidogenic disease
PCT/US2005/028166 WO2006020581A2 (en) 2004-08-09 2005-08-09 Prevention and treatment of synucleinopathic and amyloidogenic disease

Publications (1)

Publication Number Publication Date
BRPI0514199A true BRPI0514199A (pt) 2008-06-03

Family

ID=35908081

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0514199-0A BRPI0514199A (pt) 2004-08-09 2005-08-09 método de efetuar profilaxia ou tratar uma doença, composição farmacêutica, anticorpo monoclonal, célula de hibridoma, e, método de triar um agente, de humanizar anticorpo monoclonal 8a5 ou anticorpo monoclonal 6h7 e de produzir uma forma quimérica de anticorpo monoclonal 8a5 ou anticorpo monoclonal 6h7

Country Status (22)

Country Link
US (2) US8506959B2 (pt)
EP (2) EP1793855B2 (pt)
JP (1) JP5211290B2 (pt)
KR (2) KR20070042566A (pt)
AU (1) AU2005273969B2 (pt)
BR (1) BRPI0514199A (pt)
CA (1) CA2576672C (pt)
CY (1) CY1121408T1 (pt)
DK (1) DK1793855T4 (pt)
ES (1) ES2705586T5 (pt)
HR (1) HRP20190008T4 (pt)
HU (1) HUE041974T2 (pt)
IL (2) IL181061A (pt)
LT (1) LT1793855T (pt)
ME (1) ME03302B (pt)
NO (1) NO20071267L (pt)
NZ (1) NZ553621A (pt)
PL (1) PL1793855T5 (pt)
PT (1) PT1793855T (pt)
RS (1) RS58421B2 (pt)
SI (1) SI1793855T2 (pt)
WO (1) WO2006020581A2 (pt)

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