BRPI0406636A - Lentes de contato e métodos e composições de gotas oftálmicas de reumidificação - Google Patents
Lentes de contato e métodos e composições de gotas oftálmicas de reumidificaçãoInfo
- Publication number
- BRPI0406636A BRPI0406636A BR0406636-7A BRPI0406636A BRPI0406636A BR PI0406636 A BRPI0406636 A BR PI0406636A BR PI0406636 A BRPI0406636 A BR PI0406636A BR PI0406636 A BRPI0406636 A BR PI0406636A
- Authority
- BR
- Brazil
- Prior art keywords
- contact lenses
- rehumidification
- compositions
- formulations
- sym
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- 239000003889 eye drop Substances 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- 229920002385 Sodium hyaluronate Polymers 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 239000003139 biocide Substances 0.000 abstract 1
- 229910021538 borax Inorganic materials 0.000 abstract 1
- 230000003750 conditioning effect Effects 0.000 abstract 1
- 239000003974 emollient agent Substances 0.000 abstract 1
- 229940012356 eye drops Drugs 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 230000003278 mimic effect Effects 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940010747 sodium hyaluronate Drugs 0.000 abstract 1
- 235000010339 sodium tetraborate Nutrition 0.000 abstract 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 abstract 1
- 238000004659 sterilization and disinfection Methods 0.000 abstract 1
- BSVBQGMMJUBVOD-UHFFFAOYSA-N trisodium borate Chemical compound [Na+].[Na+].[Na+].[O-]B([O-])[O-] BSVBQGMMJUBVOD-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Eyeglasses (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
"LENTES DE CONTATO E MéTODOS E COMPOSIçõES DE GOTAS OFTáLMICAS DE REUMIDIFICAçãO". A presente invenção refere-se a formulações oftálmicas que compreendem o ácido hialurónico (hialuronato de sódio) como o primeiro ingrediente ativo demulcente, complexo de óxi-cloro estabilizado (disponível comercialmente como OcuPure¬ <sym>¬ da Advanced Medical Optics, Purite <sym> da Aliergan e Purogene da Biocide) para eficácia conservante, sais balanceados que imitam a película de lágrima e borato de sódio como um tampão. Em uma modalidade, as formulações estáveis de preferidas podem ser usadas no olho humano com ou sem lentes de contato. Em uma outra modalidade, as formulações de preferência também podem ser usadas como uma solução para o armazenamento e o condicionamento de lentes de contato em seguida à desinfecção.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43885703P | 2003-01-08 | 2003-01-08 | |
| US43884303P | 2003-01-08 | 2003-01-08 | |
| PCT/US2004/000298 WO2004062660A1 (en) | 2003-01-08 | 2004-01-08 | Contact lens and eye drop rewetter compositions and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0406636A true BRPI0406636A (pt) | 2005-12-06 |
Family
ID=32718011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0406636-7A BRPI0406636A (pt) | 2003-01-08 | 2004-01-08 | Lentes de contato e métodos e composições de gotas oftálmicas de reumidificação |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20040137079A1 (pt) |
| EP (1) | EP1581211A1 (pt) |
| JP (1) | JP2006516032A (pt) |
| AU (1) | AU2004204734B2 (pt) |
| BR (1) | BRPI0406636A (pt) |
| CA (1) | CA2512320A1 (pt) |
| TW (1) | TWI339747B (pt) |
| WO (1) | WO2004062660A1 (pt) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040185068A1 (en) * | 2003-03-18 | 2004-09-23 | Zhi-Jian Yu | Self-emulsifying compositions, methods of use and preparation |
| US20050196370A1 (en) * | 2003-03-18 | 2005-09-08 | Zhi-Jian Yu | Stable ophthalmic oil-in-water emulsions with sodium hyaluronate for alleviating dry eye |
| US20060251685A1 (en) * | 2003-03-18 | 2006-11-09 | Zhi-Jian Yu | Stable ophthalmic oil-in-water emulsions with Omega-3 fatty acids for alleviating dry eye |
| US20040191332A1 (en) * | 2003-03-27 | 2004-09-30 | Allergan, Inc. | Preserved ophthalmic compositions |
| US7947295B2 (en) | 2003-06-13 | 2011-05-24 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of two polymers |
| CA2839847C (en) * | 2003-06-13 | 2016-03-15 | Masood A. Chowhan | Ophthalmic compositions containing a synergistic combination of two polymers |
| US7722808B2 (en) | 2003-09-12 | 2010-05-25 | Novartis Ag | Method and kits for sterilizing and storing soft contact lenses |
| US20050202983A1 (en) * | 2004-03-12 | 2005-09-15 | Erning Xia | Prevention of loss of tight cell junctions using carbohydrate-containing compositions |
| US8288362B2 (en) * | 2004-05-07 | 2012-10-16 | S.K. Pharmaceuticals, Inc. | Stabilized glycosaminoglycan preparations and related methods |
| WO2005110439A2 (en) * | 2004-05-07 | 2005-11-24 | S.K. Pharmaceuticals, Inc. | Stabilized hyaluronan preparations and related methods |
| EP1802357B2 (en) * | 2004-10-01 | 2013-09-18 | Menicon Singapore Pte Ltd. | Method for sterilising contact lens with package solution |
| US8569367B2 (en) | 2004-11-16 | 2013-10-29 | Allergan, Inc. | Ophthalmic compositions and methods for treating eyes |
| US9297928B2 (en) | 2004-11-22 | 2016-03-29 | Johnson & Johnson Vision Care, Inc. | Ophthalmic compositions comprising polyether substituted polymers |
| KR20070114130A (ko) | 2005-02-14 | 2007-11-29 | 존슨 앤드 존슨 비젼 케어, 인코포레이티드 | 착용감이 편안한 안용 장치 및 이의 제조방법 |
| TW200722109A (en) * | 2005-03-31 | 2007-06-16 | Bausch & Lomb | Polysaccharide and polyol composition for treating dry eye and related methods of manufacture and methods of use |
| ES2285910B1 (es) * | 2005-09-08 | 2008-12-16 | Vicente Tormo Maicas | Procedimiento para la elaboracion de la formula de hialuronato sodico para la curacion y cicatrizacion de heridas. |
| US9052529B2 (en) | 2006-02-10 | 2015-06-09 | Johnson & Johnson Vision Care, Inc. | Comfortable ophthalmic device and methods of its production |
| EP2070518A2 (en) | 2006-07-25 | 2009-06-17 | Osmotica Corp. | Ophthalmic solutions |
| US20080095754A1 (en) * | 2006-10-18 | 2008-04-24 | Burke Susan E | Ophthalmic compositions comprising diglycine |
| US8138156B2 (en) * | 2006-10-18 | 2012-03-20 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
| US20080141628A1 (en) * | 2006-12-15 | 2008-06-19 | Bausch & Lomb Incorporated | Packaging Solutions |
| US20080166393A1 (en) * | 2007-01-05 | 2008-07-10 | Grant Robert K | Eye Medication Delivery System |
| US8759321B2 (en) * | 2007-06-13 | 2014-06-24 | Bausch & Lomb Incorporated | Ophthalmic composition with hyaluronic acid and polymeric biguanide |
| US8689971B2 (en) * | 2007-08-31 | 2014-04-08 | Novartis Ag | Contact lens packaging solutions |
| TWI551305B (zh) * | 2007-08-31 | 2016-10-01 | 諾華公司 | 相對黏稠封裝溶液之用途 |
| US8119112B2 (en) * | 2008-01-31 | 2012-02-21 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid |
| US9096819B2 (en) | 2008-01-31 | 2015-08-04 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer |
| US8629099B2 (en) * | 2008-03-25 | 2014-01-14 | Bausch & Lomb Incorporated | Ophthalmic compositions comprising a dipeptide |
| WO2010003797A1 (en) * | 2008-07-09 | 2010-01-14 | Novozymes Biopharma Dk A/S | Hyaluronic acid for corneal wound healing |
| CL2009001585A1 (es) | 2008-07-15 | 2011-04-29 | Basf Corp | Composicion fluida espesa, que comprende dioxido de cloro, un espesante, un fluido acuoso, y anion de oxido de clror; composision fluida espesa y su metodo de preparacion |
| US20100286010A1 (en) * | 2008-09-03 | 2010-11-11 | Erning Xia | Ophthalmic Compositions with Hyaluronic Acid |
| CA2736380C (en) * | 2008-09-15 | 2013-05-28 | Bausch & Lomb Incorporated | Compositions comprising polymers having amino sugar units and methods of making and using same |
| US20100178317A1 (en) * | 2009-01-09 | 2010-07-15 | Burke Susan E | Lens Care Solutions with Hyaluronic Acid |
| US8311625B2 (en) | 2009-02-04 | 2012-11-13 | Basf Corporation | Chlorine dioxide treatment for biological tissue |
| IT1394223B1 (it) | 2009-05-15 | 2012-06-01 | Thea Sas Lab | Kit per la valutazione e la selezione personalizzata di lacrime artificiali |
| JP5601805B2 (ja) * | 2009-08-24 | 2014-10-08 | キユーピー株式会社 | 経口用ドライアイ改善剤、ならびに前記経口用ドライアイ改善剤を含む食品組成物および医薬品組成物 |
| TW201127423A (en) * | 2009-12-17 | 2011-08-16 | Alcon Res Ltd | Ophthalmic solutions with improved disinfection profiles |
| AT511164A1 (de) | 2011-03-03 | 2012-09-15 | Croma Pharma Gmbh | Verwendung eines viskoelastischen fluids zur herstellung eines medizinproduktes für die chirurgische behandlung des auges |
| ES2797650T3 (es) | 2011-12-07 | 2020-12-03 | Allergan Inc | Administración de lípido eficiente a película lagrimal humana usando un sistema de emulsión sensible a sal |
| US9907826B2 (en) | 2011-12-07 | 2018-03-06 | Allergan, Inc. | Efficient lipid delivery to human tear film using a salt-sensitive emulsion system |
| US8664180B2 (en) | 2012-02-06 | 2014-03-04 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
| US8324171B1 (en) | 2012-02-06 | 2012-12-04 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
| AU2013222801B2 (en) * | 2012-02-24 | 2015-09-17 | Bausch & Lomb Incorporated | Ophthalmic compositions with alkoxylated natural waxes |
| PT2950783T (pt) * | 2013-02-01 | 2019-08-21 | Allergan Inc | Lágrimas artificiais compreendendo hialuronato de sódio e carboximetilcelulose |
| WO2016013993A1 (en) | 2014-07-25 | 2016-01-28 | Imuneks Farma Llac Sanayi Ve Ticaret A.Ş. | Stable preservative free ophthalmic formulations of opioid antagonists |
| JP6768653B2 (ja) | 2014-11-25 | 2020-10-14 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | 安定したオメガ−３眼科用組成物 |
| JP6595120B2 (ja) | 2015-12-03 | 2019-10-23 | ノバルティス アーゲー | コンタクトレンズパッケージング溶液 |
| TWI609957B (zh) * | 2016-06-27 | 2018-01-01 | 晶碩光學股份有限公司 | 用以處理隱形眼鏡之溶液及隱形眼鏡的包裝系統 |
| IT201700009786A1 (it) * | 2017-01-30 | 2018-07-30 | For Health Pharma S R L | Sostituto lacrimale |
| JP7104553B2 (ja) * | 2018-03-30 | 2022-07-21 | ロート製薬株式会社 | 眼科組成物 |
| EP3784354A1 (en) | 2018-04-27 | 2021-03-03 | Allergan, Inc. | Sodium chlorite compositions with enhanced anti-microbial efficacy and reduced toxicity |
| CN112741105A (zh) * | 2019-10-30 | 2021-05-04 | 永胜光学股份有限公司 | 具有高效抗微生物能力与润滑效果的溶液 |
| TWI821845B (zh) * | 2021-12-29 | 2023-11-11 | 永勝光學股份有限公司 | 應用於眼用鏡片的溶液 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4141973A (en) * | 1975-10-17 | 1979-02-27 | Biotrics, Inc. | Ultrapure hyaluronic acid and the use thereof |
| IT1212892B (it) * | 1983-10-11 | 1989-11-30 | Della Valle Francesco | Acido ialuronico ottenuto per mezzodi filtrazione molecolare sprovvisto di attivita' infiammatoria e sua utilizzazione terapeutica |
| US4478189A (en) * | 1982-12-08 | 1984-10-23 | Lucas Industries | Fuel injection system |
| US5409904A (en) * | 1984-11-13 | 1995-04-25 | Alcon Laboratories, Inc. | Hyaluronic acid compositions and methods |
| US4620979A (en) * | 1985-08-02 | 1986-11-04 | Schachar Ronald A | Ophthalmological irrigating solution containing ascorbate |
| IL80298A (en) * | 1986-10-14 | 1993-01-31 | Res & Dev Co Ltd | Eye drops |
| IL92351A (en) * | 1988-11-29 | 1994-02-27 | Allergan Inc Irvine | Aqueous opthalmic solutions containing stabilized chlorine dioxide and an inorganic salt |
| US5521222A (en) * | 1989-09-28 | 1996-05-28 | Alcon Laboratories, Inc. | Topical ophthalmic pharmaceutical vehicles |
| US5141928B1 (en) * | 1989-12-20 | 1995-11-14 | Brujo Inc | Ophthalmic medication |
| US5358706A (en) * | 1992-09-30 | 1994-10-25 | Union Carbide Chemicals & Plastics Technology Corporation | Muco-adhesive polymers |
| US5736165A (en) * | 1993-05-25 | 1998-04-07 | Allergan | In-the-eye use of chlorine dioxide-containing compositions |
| IT1273011B (it) * | 1994-07-25 | 1997-07-01 | Trhecnopharma S A | Preparato oftalmico per l'uso come lacrima artificiale |
| US5858346A (en) * | 1997-05-09 | 1999-01-12 | Allergan | Compositions and methods for enhancing contact lens wearability |
| US5989535A (en) * | 1997-08-15 | 1999-11-23 | Soma Technologies | Polymeric bioadhesive emulsions and suspensions and methods of treatment |
| EP1119347B1 (en) * | 1998-10-08 | 2005-03-02 | Hampar L. Karagoezian | Synergistic antimicrobial, dermatological and ophthalmic preparations containing chlorite and hydrogen peroxide |
| US6552020B1 (en) * | 1999-07-30 | 2003-04-22 | Allergan, Inc. | Compositions including antibiotics and methods for using same |
| US6592907B2 (en) * | 1999-10-04 | 2003-07-15 | Hampar L. Karagoezian | Synergistic antimicrobial ophthalmic and dermatologic preparations containing chlorite and hydrogen peroxide |
| IL151530A0 (en) * | 2000-07-14 | 2003-04-10 | Allergan Sales Inc | Compositions containing alpha-2-adrenergic agonist components |
| DK2153819T3 (da) * | 2000-07-14 | 2012-12-03 | Allergan Inc | Anvendelse af en opløselighedsforbedrende bestanddel i en vandig sammensætning omfattende brimonidintartrat |
| DE10038955C2 (de) * | 2000-08-09 | 2002-07-11 | Infineon Technologies Ag | Verfahren zur Herstellung eines Bipolartransistors |
| PE20020578A1 (es) * | 2000-10-10 | 2002-08-14 | Upjohn Co | Una composicion de antibiotico topico para el tratamiento de infecciones oculares |
| JP3455852B2 (ja) * | 2000-12-26 | 2003-10-14 | 株式会社オフテクス | 洗眼液組成物 |
| AU2002228449B2 (en) * | 2001-01-09 | 2007-12-06 | Louis Johan Wagenaar | Procedure and composition of treatment and/or care of the eye |
| AR034371A1 (es) * | 2001-06-08 | 2004-02-18 | Novartis Ag | Composiciones farmaceuticas |
| US7045121B2 (en) * | 2001-12-14 | 2006-05-16 | Allergan, Inc. | Ophthalmic compositions for lubricating eyes and methods for making and using same |
| US6982079B2 (en) * | 2002-04-26 | 2006-01-03 | Allergan, Inc. | Compositions for treating hyperemia |
-
2004
- 2004-01-07 US US10/752,759 patent/US20040137079A1/en not_active Abandoned
- 2004-01-08 AU AU2004204734A patent/AU2004204734B2/en not_active Expired
- 2004-01-08 BR BR0406636-7A patent/BRPI0406636A/pt not_active IP Right Cessation
- 2004-01-08 EP EP04700834A patent/EP1581211A1/en not_active Ceased
- 2004-01-08 CA CA002512320A patent/CA2512320A1/en not_active Abandoned
- 2004-01-08 WO PCT/US2004/000298 patent/WO2004062660A1/en not_active Ceased
- 2004-01-08 JP JP2006500819A patent/JP2006516032A/ja active Pending
- 2004-01-08 TW TW093100476A patent/TWI339747B/zh not_active IP Right Cessation
-
2005
- 2005-07-28 US US11/193,540 patent/US20050260280A1/en not_active Abandoned
- 2005-07-29 US US11/192,718 patent/US20050266089A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006516032A (ja) | 2006-06-15 |
| CA2512320A1 (en) | 2004-07-29 |
| US20050266089A1 (en) | 2005-12-01 |
| TWI339747B (en) | 2011-04-01 |
| AU2004204734A1 (en) | 2004-07-29 |
| EP1581211A1 (en) | 2005-10-05 |
| AU2004204734B2 (en) | 2008-04-10 |
| US20040137079A1 (en) | 2004-07-15 |
| TW200419217A (en) | 2004-10-01 |
| WO2004062660A1 (en) | 2004-07-29 |
| US20050260280A1 (en) | 2005-11-24 |
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