BRPI0407694A - métodos de usar células derivadas do tecido adiposo no tratamento de condições cardiovasculares - Google Patents
métodos de usar células derivadas do tecido adiposo no tratamento de condições cardiovascularesInfo
- Publication number
- BRPI0407694A BRPI0407694A BRPI0407694-0A BRPI0407694A BRPI0407694A BR PI0407694 A BRPI0407694 A BR PI0407694A BR PI0407694 A BRPI0407694 A BR PI0407694A BR PI0407694 A BRPI0407694 A BR PI0407694A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- cardiovascular conditions
- fat
- treatment
- derived cells
- Prior art date
Links
- 230000002526 effect on cardiovascular system Effects 0.000 title abstract 2
- 210000000577 adipose tissue Anatomy 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 210000000130 stem cell Anatomy 0.000 abstract 2
- 239000000654 additive Substances 0.000 abstract 1
- 230000010036 cardiovascular benefit Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1384—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from adipose-derived stem cells [ADSC], from adipose stromal stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Developmental Biology & Embryology (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Hospice & Palliative Care (AREA)
- Virology (AREA)
- Immunology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
"MéTODOS DE USAR CéLULAS DERIVADAS DO TECIDO ADIPOSO NO TRATAMENTO DE CONDIçõES CARDIOVASCULARES". Células presentes em tecido lipoaspirado processado são usadas para tratar pacientes, incluindo pacientes com condições, doenças ou desordens vasculares. Métodos de tratamento de pacientes incluem processamento do tecido adiposo pára entregar uma quantidade concentrada de células-tronco obtidas do tecido adiposo a um paciente. os métodos podem ser praticados em um sistema fechado, de maneira tal que as células-tronco não fiquem expostas a um ambiente externo antes de ser administrada a um paciente. Dessa maneira, em um método preferido, células presentes em lipoaspirado processado são colocadas diretamente em um recipiente juntamente com tais aditivos necessários para promover, engendrar ou suportar um beneficio cardiovascular terapêutico.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44927903P | 2003-02-20 | 2003-02-20 | |
| US46291103P | 2003-04-15 | 2003-04-15 | |
| PCT/US2004/005117 WO2004074457A2 (en) | 2003-02-20 | 2004-02-20 | Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0407694A true BRPI0407694A (pt) | 2006-03-01 |
Family
ID=32912320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0407694-0A BRPI0407694A (pt) | 2003-02-20 | 2004-02-20 | métodos de usar células derivadas do tecido adiposo no tratamento de condições cardiovasculares |
Country Status (13)
| Country | Link |
|---|---|
| EP (2) | EP2422622B1 (pt) |
| JP (1) | JP4971787B2 (pt) |
| KR (2) | KR101310578B1 (pt) |
| AT (1) | ATE524070T1 (pt) |
| AU (1) | AU2004213858B2 (pt) |
| BR (1) | BRPI0407694A (pt) |
| CA (1) | CA2516510C (pt) |
| DK (1) | DK1599575T3 (pt) |
| ES (1) | ES2373551T3 (pt) |
| IL (2) | IL170354A (pt) |
| MX (1) | MXPA05009044A (pt) |
| RU (1) | RU2372924C2 (pt) |
| WO (1) | WO2004074457A2 (pt) |
Families Citing this family (53)
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| US20050048035A1 (en) | 2001-12-07 | 2005-03-03 | Fraser John K. | Methods of using regenerative cells in the treatment of stroke and related diseases and disorders |
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| US20050095228A1 (en) | 2001-12-07 | 2005-05-05 | Fraser John K. | Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders |
| KR101150666B1 (ko) | 2001-12-07 | 2012-07-05 | 사이토리 테라퓨틱스, 인크. | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법 |
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-
2004
- 2004-02-20 EP EP11180767.3A patent/EP2422622B1/en not_active Expired - Lifetime
- 2004-02-20 KR KR1020057015336A patent/KR101310578B1/ko not_active Expired - Fee Related
- 2004-02-20 BR BRPI0407694-0A patent/BRPI0407694A/pt not_active Application Discontinuation
- 2004-02-20 WO PCT/US2004/005117 patent/WO2004074457A2/en not_active Ceased
- 2004-02-20 AU AU2004213858A patent/AU2004213858B2/en not_active Ceased
- 2004-02-20 DK DK04713403.6T patent/DK1599575T3/da active
- 2004-02-20 KR KR1020127005073A patent/KR20120038534A/ko not_active Withdrawn
- 2004-02-20 AT AT04713403T patent/ATE524070T1/de not_active IP Right Cessation
- 2004-02-20 ES ES04713403T patent/ES2373551T3/es not_active Expired - Lifetime
- 2004-02-20 MX MXPA05009044A patent/MXPA05009044A/es active IP Right Grant
- 2004-02-20 JP JP2006503755A patent/JP4971787B2/ja not_active Expired - Lifetime
- 2004-02-20 CA CA2516510A patent/CA2516510C/en not_active Expired - Fee Related
- 2004-02-20 RU RU2005128964/14A patent/RU2372924C2/ru not_active IP Right Cessation
- 2004-02-20 EP EP04713403A patent/EP1599575B9/en not_active Expired - Lifetime
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2005
- 2005-08-18 IL IL170354A patent/IL170354A/en active IP Right Grant
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Also Published As
| Publication number | Publication date |
|---|---|
| JP4971787B2 (ja) | 2012-07-11 |
| IL170354A (en) | 2011-07-31 |
| MXPA05009044A (es) | 2006-03-17 |
| EP2422622B1 (en) | 2017-01-11 |
| RU2005128964A (ru) | 2006-03-20 |
| CA2516510C (en) | 2012-07-10 |
| AU2004213858A1 (en) | 2004-09-02 |
| CA2516510A1 (en) | 2004-09-02 |
| EP1599575B9 (en) | 2012-03-14 |
| WO2004074457A2 (en) | 2004-09-02 |
| ATE524070T1 (de) | 2011-09-15 |
| DK1599575T3 (da) | 2012-01-16 |
| WO2004074457A3 (en) | 2006-05-18 |
| KR101310578B1 (ko) | 2013-09-23 |
| IL214373A (en) | 2014-09-30 |
| ES2373551T3 (es) | 2012-02-06 |
| KR20120038534A (ko) | 2012-04-23 |
| EP1599575A4 (en) | 2007-08-08 |
| JP2007525422A (ja) | 2007-09-06 |
| AU2004213858B2 (en) | 2009-01-22 |
| EP1599575B1 (en) | 2011-09-14 |
| KR20050109941A (ko) | 2005-11-22 |
| EP2422622A1 (en) | 2012-02-29 |
| RU2372924C2 (ru) | 2009-11-20 |
| IL214373A0 (en) | 2011-09-27 |
| HK1102085A1 (en) | 2007-11-02 |
| EP1599575A2 (en) | 2005-11-30 |
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