BRPI0407694A - métodos de usar células derivadas do tecido adiposo no tratamento de condições cardiovasculares - Google Patents

métodos de usar células derivadas do tecido adiposo no tratamento de condições cardiovasculares

Info

Publication number
BRPI0407694A
BRPI0407694A BRPI0407694-0A BRPI0407694A BRPI0407694A BR PI0407694 A BRPI0407694 A BR PI0407694A BR PI0407694 A BRPI0407694 A BR PI0407694A BR PI0407694 A BRPI0407694 A BR PI0407694A
Authority
BR
Brazil
Prior art keywords
methods
cardiovascular conditions
fat
treatment
derived cells
Prior art date
Application number
BRPI0407694-0A
Other languages
English (en)
Inventor
John K Fraser
Marc H Hedrick
Min Zhu
Brian M Strem
Eric Daniels
Isabella Wulur
Original Assignee
Macropore Biosurgery Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32912320&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0407694(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Macropore Biosurgery Inc filed Critical Macropore Biosurgery Inc
Publication of BRPI0407694A publication Critical patent/BRPI0407694A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
    • C12N2506/1384—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from adipose-derived stem cells [ADSC], from adipose stromal stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"MéTODOS DE USAR CéLULAS DERIVADAS DO TECIDO ADIPOSO NO TRATAMENTO DE CONDIçõES CARDIOVASCULARES". Células presentes em tecido lipoaspirado processado são usadas para tratar pacientes, incluindo pacientes com condições, doenças ou desordens vasculares. Métodos de tratamento de pacientes incluem processamento do tecido adiposo pára entregar uma quantidade concentrada de células-tronco obtidas do tecido adiposo a um paciente. os métodos podem ser praticados em um sistema fechado, de maneira tal que as células-tronco não fiquem expostas a um ambiente externo antes de ser administrada a um paciente. Dessa maneira, em um método preferido, células presentes em lipoaspirado processado são colocadas diretamente em um recipiente juntamente com tais aditivos necessários para promover, engendrar ou suportar um beneficio cardiovascular terapêutico.
BRPI0407694-0A 2003-02-20 2004-02-20 métodos de usar células derivadas do tecido adiposo no tratamento de condições cardiovasculares BRPI0407694A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44927903P 2003-02-20 2003-02-20
US46291103P 2003-04-15 2003-04-15
PCT/US2004/005117 WO2004074457A2 (en) 2003-02-20 2004-02-20 Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions

Publications (1)

Publication Number Publication Date
BRPI0407694A true BRPI0407694A (pt) 2006-03-01

Family

ID=32912320

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0407694-0A BRPI0407694A (pt) 2003-02-20 2004-02-20 métodos de usar células derivadas do tecido adiposo no tratamento de condições cardiovasculares

Country Status (13)

Country Link
EP (2) EP1599575B9 (pt)
JP (1) JP4971787B2 (pt)
KR (2) KR20120038534A (pt)
AT (1) ATE524070T1 (pt)
AU (1) AU2004213858B2 (pt)
BR (1) BRPI0407694A (pt)
CA (1) CA2516510C (pt)
DK (1) DK1599575T3 (pt)
ES (1) ES2373551T3 (pt)
IL (2) IL170354A (pt)
MX (1) MXPA05009044A (pt)
RU (1) RU2372924C2 (pt)
WO (1) WO2004074457A2 (pt)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030007954A1 (en) 1999-04-12 2003-01-09 Gail K. Naughton Methods for using a three-dimensional stromal tissue to promote angiogenesis
US9597395B2 (en) 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US7514075B2 (en) 2001-12-07 2009-04-07 Cytori Therapeutics, Inc. Systems and methods for separating and concentrating adipose derived stem cells from tissue
US7771716B2 (en) 2001-12-07 2010-08-10 Cytori Therapeutics, Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
CA2469370C (en) 2001-12-07 2014-07-08 Macropore Biosurgery, Inc. Adipose-derived cell processing unit
US8105580B2 (en) 2001-12-07 2012-01-31 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to promote wound healing
US7595043B2 (en) 2001-12-07 2009-09-29 Cytori Therapeutics, Inc. Method for processing and using adipose-derived stem cells
US7585670B2 (en) 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
US20050095228A1 (en) 2001-12-07 2005-05-05 Fraser John K. Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
SG146666A1 (en) * 2003-09-17 2008-10-30 Macropore Biosurgery Inc Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
AU2004280616A1 (en) 2003-10-08 2005-04-21 Vet-Stem Inc. Methods of preparing and using stem cell compositions and kits comprising the same
WO2006014156A1 (en) * 2004-07-02 2006-02-09 Macropore Biosurgery, Inc. Systems and methods for isolating and using clinically safe adipose derived regenerative cells
ATE500855T1 (de) * 2004-11-22 2011-03-15 Theregen Inc Vewendung von dreidimensionalem kultiviertem gewebe zur behandlung von kongestivem herzversagen
AU2005322873B2 (en) 2004-12-30 2011-09-01 Primegen Biotech, Llc Adipose-derived stem cells for tissue regeneration and wound healing
KR100811537B1 (ko) 2005-03-11 2008-03-20 양영일 지방조직 치료제의 조성, 이들 제조방법 및 그의 전달방법
WO2006127007A2 (en) * 2005-05-25 2006-11-30 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
AU2013216683B2 (en) * 2005-05-25 2016-06-23 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
RU2355325C2 (ru) * 2006-08-01 2009-05-20 Федеральное государственное учреждение Новосибирский научно-исследовательский институт патологии кровообращения имени акад. Е.Н. Мешалкина Федерального агентства по высокотехнологичной медицинской помощи Способ лечения инфаркта миокарда
ES2392729T5 (es) * 2007-09-19 2015-08-28 Pluristem Ltd. Células adherentes de tejidos adiposos o de placenta y uso de las mismas en terapia
CN101801352B (zh) * 2007-11-30 2013-04-03 Rnl生物技术株式会社 用于治疗小便失禁的含有来自蜕膜或脂肪的干细胞的细胞治疗剂
JP5015865B2 (ja) * 2008-06-09 2012-08-29 オリンパス株式会社 脂肪組織洗浄装置
KR20100008763A (ko) * 2008-07-16 2010-01-26 주식회사 알앤엘바이오 지방조직 유래 다분화능 줄기세포의 배양물 및 그 추출 단백질을 함유한 화장료용 조성물
WO2010021993A1 (en) 2008-08-19 2010-02-25 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease
EP2424463B1 (en) 2009-05-01 2016-12-28 Bimini Technologies LLC Systems, methods and compositions for optimizing tissue and cell enriched grafts
JP5710885B2 (ja) * 2010-02-25 2015-04-30 オリンパス株式会社 脂肪由来細胞の賦活化方法および移植材の製造方法
EP2601956B1 (en) * 2010-08-06 2017-04-12 Osaka University Islets of langerhans transplant using islets of langerhans and adipose tissue derived stem cells
WO2012051278A1 (en) 2010-10-12 2012-04-19 Tanis Kevin J Medical device
EP2818173B1 (en) * 2012-02-24 2021-09-22 Saeki, Masanori Cell preparation including fat cell
EP2837682B1 (en) * 2012-04-13 2017-09-20 Jeong Chan Ra Use of aspirin in composition for preventing stem cell disruption and aggregation
MX2014014266A (es) 2012-05-22 2015-06-23 Smith & Nephew Aparatos y metodos para terapia de heridas.
DE102013209718B4 (de) * 2012-06-22 2015-09-10 Human Med Ag Vorrichtung zum Separieren von adulten Stammzellen
RU2522778C2 (ru) * 2012-10-08 2014-07-20 Федеральное государственное бюджетное учреждение "Российский кардиологический научно-производственный комплекс" Министерства здравоохранения Российской Федерации Средство для лечения ишемических поражений тканей и способ его применения
US9737649B2 (en) 2013-03-14 2017-08-22 Smith & Nephew, Inc. Systems and methods for applying reduced pressure therapy
WO2014151930A2 (en) 2013-03-14 2014-09-25 Smith & Nephew Inc. Systems and methods for applying reduced pressure therapy
US9580678B2 (en) 2013-06-21 2017-02-28 The Regents Of The University Of California Microfluidic tumor tissue dissociation device
US12133789B2 (en) 2014-07-31 2024-11-05 Smith & Nephew, Inc. Reduced pressure therapy apparatus construction and control
WO2017062042A1 (en) 2015-10-07 2017-04-13 Smith & Nephew, Inc. Systems and methods for applying reduced pressure therapy
US10722540B1 (en) 2016-02-01 2020-07-28 The Regents Of The University Of California Microfluidic device and method for shear stress-induced transformation of cells
EP4393526A3 (en) 2016-02-12 2024-08-14 Smith & Nephew, Inc Systems and methods for detecting operational conditions of reduced pressure therapy
RU2627606C1 (ru) * 2016-05-05 2017-08-09 Константин Валентинович Котенко Способ обработки липоаспирата
CN109069713A (zh) 2016-05-13 2018-12-21 史密夫和内修有限公司 负压伤口治疗系统中的自动伤口联接检测
CA3051051A1 (en) 2016-06-08 2017-12-14 The Regents Of The University Of California Method and device for processing tissues and cells
US12263294B2 (en) 2016-09-28 2025-04-01 T.J.Smith And Nephew, Limited Systems and methods for operating negative pressure wound therapy devices
JP7063887B2 (ja) 2016-09-29 2022-05-09 スミス アンド ネフュー インコーポレイテッド 陰圧創傷治療システムにおける構成要素の構築及び保護
CN110545766A (zh) 2017-03-07 2019-12-06 史密夫和内修有限公司 包括天线的减压治疗系统和方法
WO2019014141A1 (en) 2017-07-10 2019-01-17 Smith & Nephew, Inc. SYSTEMS AND METHODS FOR INTERACTING DIRECTLY WITH A COMMUNICATION MODULE OF A WOUND PROCESSING APPARATUS
CN108277152B (zh) * 2018-04-04 2023-10-13 博品(上海)生物医药科技有限公司 细胞复苏用无菌换液装置及利用该装置进行细胞复苏换液的方法
GB201820668D0 (en) 2018-12-19 2019-01-30 Smith & Nephew Inc Systems and methods for delivering prescribed wound therapy
EP3931840A1 (en) 2019-02-27 2022-01-05 T.J.Smith And Nephew, Limited Systems and methods for synchronizing a device clock in wound monitoring and/or treatment systems
GB201911693D0 (en) 2019-08-15 2019-10-02 Smith & Nephew Systems and methods for monitoring essential performance of wound therapy
EP4101440A4 (en) * 2020-02-04 2024-02-21 Hierabio Inc. COMPOSITION FOR INTRAPERICARDIAL INJECTION WITH STEM CELLS AND USE THEREOF
KR20260116298A (ko) 2020-05-11 2026-07-28 신틀 헬스 테크놀로지스 인코포레이티드 조직 및 세포 처리 방법 및 장치
KR102844218B1 (ko) 2021-02-09 2025-08-11 인제대학교 산학협력단 심혈관 질환 치료를 위한 양막 유래 중간엽 줄기세포 전달체
US12582763B2 (en) 2021-04-21 2026-03-24 T.J.Smith And Nephew, Limited Communication systems and methods for negative pressure wound therapy devices

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4000275A (en) * 1969-11-24 1976-12-28 Eli Lilly And Company Immunosuppressants
US4346703A (en) 1979-01-23 1982-08-31 Baxter Travenol Laboratories, Inc. Solution container for continuous ambulatory peritoneal dialysis
US5034135A (en) 1982-12-13 1991-07-23 William F. McLaughlin Blood fractionation system and method
US5372945A (en) 1985-06-06 1994-12-13 Alchas; Paul G. Device and method for collecting and processing fat tissue and procuring microvessel endothelial cells to produce endothelial cell product
US4963489A (en) * 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5641622A (en) 1990-09-13 1997-06-24 Baxter International Inc. Continuous centrifugation process for the separation of biological components from heterogeneous cell populations
US5234608A (en) 1990-12-11 1993-08-10 Baxter International Inc. Systems and methods for processing cellular rich suspensions
JP3388352B2 (ja) 1991-10-18 2003-03-17 バクスター、インターナショナル、インコーポレイテッド 骨髄キット
ZA932660B (en) * 1992-04-17 1993-10-26 Sankyo Co Derivatives of adipogenesis inhibitory factor, their preparation and their use
US6017719A (en) 1994-06-14 2000-01-25 Nexell Therapeutics, Inc. Positive and positive/negative cell selection mediated by peptide release
US6238908B1 (en) 1995-06-07 2001-05-29 Aastrom Biosciences, Inc. Apparatus and method for maintaining and growth biological cells
FR2742662B1 (fr) 1995-12-21 1998-01-23 Centre Nat Rech Scient Anticorps anti-idiotypiques du facteur de croissance endotheliale vasculaire et leur utilisation comme medicaments
US5830714A (en) 1996-04-17 1998-11-03 Molecular Biology Resources, Inc. Biologically active fragment of bacillus stearothermophilus DNA polymerase
US5869037A (en) * 1996-06-26 1999-02-09 Cornell Research Foundation, Inc. Adenoviral-mediated gene transfer to adipocytes
WO1998022574A2 (de) 1996-11-19 1998-05-28 Roche Diagnostics Gmbh Rekombinante collagenase typ i aus clostridium histolyticum und ihre verwendung zur isolierung von zellen und zellverbänden
US5830741A (en) 1996-12-06 1998-11-03 Boehringer Mannheim Corporation Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease
US6451207B1 (en) 1997-06-04 2002-09-17 Dexter Magnetic Technologies, Inc. Magnetic cell separation device
WO1999011771A1 (en) 1997-09-04 1999-03-11 Science Research Laboratory, Inc. Cell separation using electric fields
US6251295B1 (en) 1998-01-08 2001-06-26 Nexell Therapeutics Inc. Method for recirculation washing of blood cells
US6001642A (en) 1998-06-29 1999-12-14 Wyle Laboratories, Inc. Life Sciences Bioreactor and cell culturing processes using the bioreactor
DE19841835C2 (de) 1998-09-12 2003-05-28 Fresenius Ag Zentrifugenkammer für einen Zellseparator
RU2306335C2 (ru) * 1999-03-10 2007-09-20 Юниверсити Оф Питтсбург Оф Дзе Коммонвелт Систем Оф Хайер Эдьюкейшн Стволовые клетки и решетки, полученные из жировой ткани
US6316247B1 (en) 1999-06-15 2001-11-13 University Of Pittsburgh System and method for refining liposuctioned adipose tissue
US7094874B2 (en) 2000-05-26 2006-08-22 Bristol-Myers Squibb Co. Soluble CTLA4 mutant molecules
JP2005501802A (ja) * 2001-01-23 2005-01-20 ボストン　サイエンティフィック　コーポレイション 虚血心筋を処置するための限局性心筋注入方法
US20030054331A1 (en) * 2001-09-14 2003-03-20 Stemsource, Inc. Preservation of non embryonic cells from non hematopoietic tissues
CA2469370C (en) * 2001-12-07 2014-07-08 Macropore Biosurgery, Inc. Adipose-derived cell processing unit
AU2003220424A1 (en) * 2002-03-19 2003-10-08 Advanced Research And Technology Transfer Adipose stromal stem cells for tissue and vascular modification
KR100835034B1 (ko) * 2003-12-25 2008-06-03 도꾸리쯔교세이호징 가가꾸 기쥬쯔 신꼬 기꼬 포유동물의 골수 세포 또는 제대혈 유래 세포와 지방조직을 이용한 심근 세포의 유도

Also Published As

Publication number Publication date
JP2007525422A (ja) 2007-09-06
EP1599575B9 (en) 2012-03-14
KR20120038534A (ko) 2012-04-23
AU2004213858B2 (en) 2009-01-22
RU2372924C2 (ru) 2009-11-20
IL214373A (en) 2014-09-30
KR101310578B1 (ko) 2013-09-23
AU2004213858A1 (en) 2004-09-02
ES2373551T3 (es) 2012-02-06
MXPA05009044A (es) 2006-03-17
EP1599575A4 (en) 2007-08-08
CA2516510A1 (en) 2004-09-02
KR20050109941A (ko) 2005-11-22
WO2004074457A3 (en) 2006-05-18
EP2422622B1 (en) 2017-01-11
ATE524070T1 (de) 2011-09-15
DK1599575T3 (da) 2012-01-16
HK1102085A1 (en) 2007-11-02
IL170354A (en) 2011-07-31
EP2422622A1 (en) 2012-02-29
JP4971787B2 (ja) 2012-07-11
IL214373A0 (en) 2011-09-27
RU2005128964A (ru) 2006-03-20
EP1599575A2 (en) 2005-11-30
EP1599575B1 (en) 2011-09-14
WO2004074457A2 (en) 2004-09-02
CA2516510C (en) 2012-07-10

Similar Documents

Publication Publication Date Title
DK1599575T3 (da) Fremgangsmåder til anvendelse af adipøst vævs-afledte celler i behandlingen af kardiovaskulære tilstande
PL1885382T3 (pl) Sposoby stosowania komórek pochodzących z tkanki tłuszczowej w leczeniu stanów układu sercowo-naczyniowego
WO2006014159A3 (en) Methods of using regenerative cells in the treatment of musculoskeletal disorders
WO2005034843A3 (en) Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
AU2009100401A4 (en) Method of extracting and activating adipose-derived stem cells
PL1778833T3 (pl) Sposoby stosowania komórek regeneracyjnych w celu przyspieszania gojenia się ran
EP2305276A3 (en) Processed lipoaspirate cells for use in therapy
ATE455574T1 (de) Prä-exzitations-pacing zur behandlung von hypertonie
WO2009038720A3 (en) Method and apparatus for applying light therapy
ATE432693T1 (de) Kombinationstherapie zur behandlung von diabetes und dadurch bedingten leiden sowie zur behandlung von mittels erhöhung des glp-1-spiegels im blut verbesserten leiden
ATE355852T1 (de) Verwendung von botulinum toxin zur behandlung von herz- und kreislaufskrankheiten
EP1692516A4 (en) THERAPY PROCESS
EA201001695A1 (ru) Применение эпотилона d для лечения заболеваний, связанных с тау-белком
WO2006022612A3 (en) Methods of using regenerative cells in the treatment of stroke and related diseases and disorders
WO2006014162A3 (en) Methods of using regenerative cells in the treatment of renal diseases and disorders
WO2020061067A8 (en) Compositions and methods for treating bone injury
NO20054912D0 (no) Behandling av aspergillus infeksjoner med tymosin alfa 1
Makhlynets Complex Treatment of Patients with Generalized Periodontitis with a Shallow Vestibule of the Mouth
UA70800C2 (ru) Способ оптимизации лечебного процесса
YU11102A (sh) Biomagnetni stimulator- jastuče za prste stopala namenjeno osobama sa problemima periferne cirkulacije
UA93054U (uk) Спосіб негайної дентальної імплантації з використанням аутоплазми, збагаченої факторами росту людини, та повідон-йоду
GB0501156D0 (en) General cure to diseases idea 3
UA116490U (uk) Спосіб лікування хворих на синдром залежності від алкоголю з депресивними порушеннями та з суїцидальною поведінкою

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: PAGAR RESTAURACAO.

B08H Application fees: decision cancelled [chapter 8.8 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 NA RPI 2259 DE 2204/2014.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: C12N 5/0775 (2010.01), A61K 35/12 (2006.01), C12N

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]