BRPI0408061A - tratamento médico utilizando um agonista de receptores seletivos de ep 2 - Google Patents
tratamento médico utilizando um agonista de receptores seletivos de ep 2Info
- Publication number
- BRPI0408061A BRPI0408061A BRPI0408061-0A BRPI0408061A BRPI0408061A BR PI0408061 A BRPI0408061 A BR PI0408061A BR PI0408061 A BRPI0408061 A BR PI0408061A BR PI0408061 A BRPI0408061 A BR PI0408061A
- Authority
- BR
- Brazil
- Prior art keywords
- facilitating
- receptor agonist
- treating
- repair
- medical treatment
- Prior art date
Links
- 239000000018 receptor agonist Substances 0.000 title abstract 3
- 229940044601 receptor agonist Drugs 0.000 title abstract 3
- 208000030016 Avascular necrosis Diseases 0.000 abstract 1
- 208000010392 Bone Fractures Diseases 0.000 abstract 1
- 206010017076 Fracture Diseases 0.000 abstract 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000037848 Metastatic bone disease Diseases 0.000 abstract 1
- 206010030043 Ocular hypertension Diseases 0.000 abstract 1
- 206010031264 Osteonecrosis Diseases 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 210000000845 cartilage Anatomy 0.000 abstract 1
- 210000003298 dental enamel Anatomy 0.000 abstract 1
- 230000004927 fusion Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 230000035876 healing Effects 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 210000003041 ligament Anatomy 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000002815 pulmonary hypertension Diseases 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
- 210000002435 tendon Anatomy 0.000 abstract 1
- 210000004906 toe nail Anatomy 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
- 230000036269 ulceration Effects 0.000 abstract 1
- 230000029663 wound healing Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
"TRATAMENTO MéDICO UTILIZANDO UM AGONISTA DE RECEPTORES SELETIVOS DE EP~ 2~". A presente invenção refere-se a métodos de tratamento de hipertensão pulmonar, facilitação da fusão de articulações, facilitação da reparação de tendões e ligamentos, redução da ocorrência de fratura secundária, tratamento de necrose avascular, facilitação da reparação de cartilagem, facilitação da cicatrização óssea após o transplante de membros, facilitação da regeneração do fígado, facilitação da cicatrização de feridas, redução da ocorrência de ulceração gástrica, tratamento da hipertensão, facilitação do crescimento do esmalte dentário ou de unhas dos dedos das mãos ou dos pés, tratamento de glaucoma, tratamento da hipertensão ocular e reparação das lesões provocadas por doença óssea metastática utilizando um agonista de receptores seletivos de EP~ 2~.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45188903P | 2003-03-04 | 2003-03-04 | |
| PCT/IB2004/000553 WO2004078169A1 (en) | 2003-03-04 | 2004-02-23 | Use of ep2 selective receptor agonists in medical treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0408061A true BRPI0408061A (pt) | 2006-02-14 |
Family
ID=32962656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0408061-0A BRPI0408061A (pt) | 2003-03-04 | 2004-02-23 | tratamento médico utilizando um agonista de receptores seletivos de ep 2 |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1601351A1 (pt) |
| JP (1) | JP2006519250A (pt) |
| KR (1) | KR20050105511A (pt) |
| CN (1) | CN1859903A (pt) |
| AU (1) | AU2004216898A1 (pt) |
| BR (1) | BRPI0408061A (pt) |
| CA (1) | CA2518193A1 (pt) |
| CL (1) | CL2004000412A1 (pt) |
| MX (1) | MXPA05009398A (pt) |
| NZ (1) | NZ541828A (pt) |
| PL (1) | PL378748A1 (pt) |
| TW (1) | TW200424176A (pt) |
| WO (1) | WO2004078169A1 (pt) |
| ZA (1) | ZA200506532B (pt) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0302094D0 (en) | 2003-01-29 | 2003-02-26 | Pharmagene Lab Ltd | EP4 receptor antagonists |
| US20070270489A1 (en) * | 2003-07-25 | 2007-11-22 | Ono Pharmaceutical Co., Ltd. | Remedy for Cartilage-Related Diseases |
| GB0324269D0 (en) | 2003-10-16 | 2003-11-19 | Pharmagene Lab Ltd | EP4 receptor antagonists |
| DK1848430T3 (da) | 2004-12-31 | 2017-11-06 | Dr Reddys Laboratories Ltd | Nye benzylamin-derivativer som cetp-inhibitors |
| US8604055B2 (en) | 2004-12-31 | 2013-12-10 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
| US7915316B2 (en) * | 2005-08-22 | 2011-03-29 | Allergan, Inc | Sulfonamides |
| US7696235B2 (en) | 2005-08-29 | 2010-04-13 | Allergan, Inc. | EP2 receptor agonists for treating glaucoma |
| JP5247675B2 (ja) | 2006-03-24 | 2013-07-24 | チルドレンズ メディカル センター コーポレーション | 造血性幹細胞の増殖を調節する方法 |
| NZ573964A (en) | 2006-07-28 | 2010-11-26 | Pfizer Prod Inc | isopropyl [3-({[4-(1H-pyrazol-1-yl)benzyl](pyridin-3-ylsulfonyl)-amino}methyl)phenoxy]acetate, a prostaglandin E2 receptor agonist (EP2), useful in lower intraocular pressure thereby treating glaucoma |
| JP5426389B2 (ja) * | 2006-10-20 | 2014-02-26 | チルドレンズ メディカル センター コーポレーション | 組織の再生を亢進するための方法 |
| CN101828111B (zh) * | 2007-08-21 | 2014-07-23 | 塞诺米克斯公司 | 人t2r苦味受体及其用途 |
| CN103965099A (zh) * | 2008-03-12 | 2014-08-06 | 宇部兴产株式会社 | 吡啶基氨基乙酸化合物 |
| WO2010096264A2 (en) | 2009-02-03 | 2010-08-26 | Children's Medical Center Corporation | Methods for enhancing hematopoietic stem/progenitor cell engraftment |
| US9051548B2 (en) | 2009-02-03 | 2015-06-09 | Children's Medical Center Corporation | Methods for enhancing hematopoietic stem/progenitor cell engraftment |
| PL2415763T3 (pl) | 2009-03-30 | 2016-05-31 | Ube Industries | Kompozycja farmaceutyczna do leczenia lub profilaktyki jaskry |
| WO2010116270A1 (en) | 2009-04-10 | 2010-10-14 | Pfizer Inc. | Ep2/4 agonists |
| WO2011030873A1 (ja) * | 2009-09-11 | 2011-03-17 | 宇部興産株式会社 | ベンジル化合物 |
| CN102548985A (zh) * | 2009-09-11 | 2012-07-04 | 宇部兴产株式会社 | 取代羰基化合物 |
| WO2011030872A1 (ja) * | 2009-09-11 | 2011-03-17 | 宇部興産株式会社 | スルホンアミド化合物 |
| WO2011030865A1 (ja) * | 2009-09-11 | 2011-03-17 | 宇部興産株式会社 | 置換ベンジル化合物 |
| JP2011057633A (ja) * | 2009-09-11 | 2011-03-24 | Ube Industries Ltd | ピリジルアミノ酢酸化合物を含有する医薬 |
| CN102498101A (zh) * | 2009-09-11 | 2012-06-13 | 宇部兴产株式会社 | 苯胺化合物 |
| WO2011030871A1 (ja) * | 2009-09-11 | 2011-03-17 | 宇部興産株式会社 | Ｎ－置換ヘテロアリール化合物 |
| WO2011078303A1 (ja) | 2009-12-25 | 2011-06-30 | 宇部興産株式会社 | アミノピリジン化合物 |
| KR101774223B1 (ko) | 2011-08-18 | 2017-09-12 | 닥터 레디스 레보러터리즈 리미티드 | 콜레스테릴 에스테르-전달 단백질(cetp) 억제제인 치환된 헤테로시클릭 아민 화합물 |
| HK1197238A1 (en) | 2011-09-27 | 2015-01-09 | 雷迪博士实验室有限公司 | 5 - benzylaminomethyl - 6 - aminopyrazolo [3, 4 -b] pyridine derivatives as cholesteryl ester -transfer protein (cetp) inhibitors useful for the treatment of atherosclerosis |
| CA2857640C (en) | 2011-12-02 | 2021-11-16 | Fate Therapeutics, Inc. | Enhanced stem cell composition |
| ES2682255T3 (es) | 2011-12-02 | 2018-09-19 | Fate Therapeutics, Inc. | Métodos mejorados de tratamiento de isquemia |
| EP2804605A4 (en) * | 2012-01-20 | 2015-07-08 | Acucela Inc | SUBSTITUTED HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASES |
| US20140142092A1 (en) * | 2012-11-16 | 2014-05-22 | Allergan, Inc. | Compounds and methods for skin repair |
| US10851412B2 (en) | 2013-03-15 | 2020-12-01 | Fate Therapeutics, Inc. | Cell potency assay for therapeutic potential |
| JPWO2014157672A1 (ja) | 2013-03-28 | 2017-02-16 | 宇部興産株式会社 | 置換ビアリール化合物 |
| EP4474384A1 (en) | 2014-05-13 | 2024-12-11 | Novartis AG | Compounds and compositions for inducing chondrogenesis |
| CN106397149B (zh) * | 2016-08-26 | 2019-05-21 | 大连奇凯医药科技有限公司 | 五氟苯甲醛的制备方法 |
| CN115636761B (zh) * | 2021-07-20 | 2024-07-05 | 中国石油天然气股份有限公司 | 一种油溶性表面活性剂、驱油剂及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2113787A1 (en) * | 1993-01-29 | 1994-07-30 | Nobuyuki Hamanaka | Carbocyclic sulfonamides |
| DK0951282T3 (da) * | 1996-12-20 | 2008-07-14 | Pfizer | Forebyggelse og behandling af skeletlidelse med EP2-receptorsubtype-selektive prostaglandin E2-agonister |
| UA67754C2 (uk) * | 1997-10-10 | 2004-07-15 | Пфайзер, Інк. | Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти) |
| US6376533B1 (en) * | 2000-10-20 | 2002-04-23 | Allergan Sales, Inc. | Omega-cycloalkyl 17-heteroaryl prostaglandin E2 analogs as EP2-receptor agonists |
-
2004
- 2004-02-23 AU AU2004216898A patent/AU2004216898A1/en not_active Abandoned
- 2004-02-23 JP JP2006506276A patent/JP2006519250A/ja not_active Withdrawn
- 2004-02-23 MX MXPA05009398A patent/MXPA05009398A/es unknown
- 2004-02-23 WO PCT/IB2004/000553 patent/WO2004078169A1/en not_active Ceased
- 2004-02-23 EP EP04713611A patent/EP1601351A1/en not_active Withdrawn
- 2004-02-23 CN CNA2004800085767A patent/CN1859903A/zh active Pending
- 2004-02-23 KR KR1020057016414A patent/KR20050105511A/ko not_active Ceased
- 2004-02-23 BR BRPI0408061-0A patent/BRPI0408061A/pt not_active IP Right Cessation
- 2004-02-23 PL PL378748A patent/PL378748A1/pl not_active Application Discontinuation
- 2004-02-23 CA CA002518193A patent/CA2518193A1/en not_active Abandoned
- 2004-02-23 NZ NZ541828A patent/NZ541828A/en unknown
- 2004-03-01 TW TW093105312A patent/TW200424176A/zh unknown
- 2004-03-02 CL CL200400412A patent/CL2004000412A1/es unknown
-
2005
- 2005-08-16 ZA ZA200506532A patent/ZA200506532B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006519250A (ja) | 2006-08-24 |
| CN1859903A (zh) | 2006-11-08 |
| TW200424176A (en) | 2004-11-16 |
| AU2004216898A1 (en) | 2004-09-16 |
| KR20050105511A (ko) | 2005-11-04 |
| WO2004078169A8 (en) | 2005-04-21 |
| ZA200506532B (en) | 2007-03-28 |
| NZ541828A (en) | 2008-06-30 |
| MXPA05009398A (es) | 2005-12-05 |
| CA2518193A1 (en) | 2004-09-16 |
| EP1601351A1 (en) | 2005-12-07 |
| CL2004000412A1 (es) | 2005-02-04 |
| WO2004078169A1 (en) | 2004-09-16 |
| PL378748A1 (pl) | 2006-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011. |