BRPI0408065A - pó impregnado, processo de fabricação do mesmo e sua utilização - Google Patents

pó impregnado, processo de fabricação do mesmo e sua utilização

Info

Publication number
BRPI0408065A
BRPI0408065A BRPI0408065-3A BRPI0408065A BRPI0408065A BR PI0408065 A BRPI0408065 A BR PI0408065A BR PI0408065 A BRPI0408065 A BR PI0408065A BR PI0408065 A BRPI0408065 A BR PI0408065A
Authority
BR
Brazil
Prior art keywords
manufacturing process
impregnated
phases
powder
hydrophilic
Prior art date
Application number
BRPI0408065-3A
Other languages
English (en)
Inventor
Jerome Besse
Laurence Besse
Myriam Alphonse
Original Assignee
Sarl Galenix Innovations
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sarl Galenix Innovations filed Critical Sarl Galenix Innovations
Publication of BRPI0408065A publication Critical patent/BRPI0408065A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2993—Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2993—Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
    • Y10T428/2995—Silane, siloxane or silicone coating
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2993—Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
    • Y10T428/2996—Glass particles or spheres
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

"Pó IMPREGNADO, PROCESSO DE FABRICAçãO DO MESMO E SUA UTILIZAçãO". A invenção trata de um pó que aumenta a bidisponibilidade e/ou a solubilidade de pelo menos um princípio ativo compreendendo um suporte sólido, inerte, sob forma em partículas impregnado por um meio líquido compreendendo uma fase hidrófoba e uma fase hidrófila, pelo menos um tensoativo e pelo menos um princípio ativo, caracterizado pelo fato de que o(s) princípio(s) ativo(s) é(são) dissolvido(s) em uma das ditas fases hidrófila ou hidrófoba e sob forma de suspensão na outra das ditas fases. Este pó impregnado serve de base para diversas preparações nos domínios farmacêutico, parafarmacêutico, cosmético, de complementos alimentares e agroalimentar.
BRPI0408065-3A 2003-03-06 2004-03-05 pó impregnado, processo de fabricação do mesmo e sua utilização BRPI0408065A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0302802A FR2851918B1 (fr) 2003-03-06 2003-03-06 Poudre impregnee ameliorant la biodisponibilite et/ou la solubilite et procede de fabrication
PCT/FR2004/000541 WO2004080381A2 (fr) 2003-03-06 2004-03-05 Poudre impregnee ameliorant la biodisponibilite et/ou la solubilite et procede de fabrication

Publications (1)

Publication Number Publication Date
BRPI0408065A true BRPI0408065A (pt) 2006-02-14

Family

ID=32865308

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408065-3A BRPI0408065A (pt) 2003-03-06 2004-03-05 pó impregnado, processo de fabricação do mesmo e sua utilização

Country Status (11)

Country Link
US (1) US7569274B2 (pt)
EP (1) EP1603538A2 (pt)
JP (1) JP4901469B2 (pt)
AU (1) AU2004218859B2 (pt)
BR (1) BRPI0408065A (pt)
CA (1) CA2518200C (pt)
FR (1) FR2851918B1 (pt)
MX (1) MXPA05009440A (pt)
NO (1) NO20054562L (pt)
RU (1) RU2367412C2 (pt)
WO (1) WO2004080381A2 (pt)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY142989A (en) * 2004-03-10 2011-02-14 Bayer Schering Pharma Ag Stabilised supersaturated solids of lipophilic drugs
CA2598762A1 (en) * 2005-02-25 2006-08-31 F. Hoffmann-La Roche Ag Tablets with improved drug substance dispersibility
EP1893182B8 (en) 2005-05-26 2012-04-04 Teva Women's Health, Inc. Oral dosage forms comprising progesterone and method of making and using the same
RU2309732C1 (ru) 2006-03-13 2007-11-10 Олег Ильич Эпштейн Спрессованная твердая оральная форма лекарственного препарата и способ получения твердой оральной формы лекарственного препарата
US20080160097A1 (en) * 2006-12-28 2008-07-03 Avon Products, Inc. Method for imparting a cosmetic or therapeutic benefit to a topical surface and process for making
PT3150586T (pt) 2007-02-23 2020-03-31 Gilead Sciences Inc Moduladores de propriedades farmacocinéticas de agentes terapêuticos
WO2008104852A2 (en) * 2007-02-26 2008-09-04 Wockhardt Research Centre Pharmaceutical compositions comprising adsorbate of fenofibrate
AU2008275937A1 (en) * 2007-07-19 2009-01-22 Luzenac America, Inc. Silicone coatings, methods of making silicone coated articles and coated articles therefrom
US10531681B2 (en) 2008-04-25 2020-01-14 Sensient Colors Llc Heat-triggered colorants and methods of making and using the same
EA201591353A1 (ru) 2008-05-02 2016-01-29 Джилид Сайэнс, Инк. Применение частиц твердого носителя для улучшения технологических характеристик фармацевтического агента
US20090298952A1 (en) * 2008-05-07 2009-12-03 Brimmer Karen S Platable soluble dyes
US9113647B2 (en) 2008-08-29 2015-08-25 Sensient Colors Llc Flavored and edible colored waxes and methods for precision deposition on edible substrates
US20100102142A1 (en) * 2008-10-28 2010-04-29 Daria Tagliareni Scent dispenser assembly
RU2448684C2 (ru) * 2009-01-15 2012-04-27 Федеральное бюджетное учреждение науки "Московский научно-исследовательский институт эпидемиологии и микробиологии им. Г.Н. Габричевского" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН "МНИИЭМ им. Г.Н. Габричевского" Роспотребнадзора) Препарат, содержащий биологически активные действующие вещества
KR100926952B1 (ko) 2009-06-04 2009-11-17 화인케미칼 주식회사 고분자 컴파운드용 오일함유 파우더
US11052029B2 (en) * 2009-06-16 2021-07-06 W. R. Grace & Co.-Conn. Cation compatible metal oxides and oral care compositions containing the metal oxides
US11000711B2 (en) 2009-12-29 2021-05-11 W. R. Grace & Co.-Conn. Compositions for forming films having a desired degree of obscuration and methods of making and using the same
US10993879B2 (en) 2010-02-08 2021-05-04 Shenzhen Evergreen Therapeutics Co., Ltd. Pulmonary delivery of progestogen
US10987361B2 (en) 2010-02-08 2021-04-27 Shenzhen Evergreen Therapeutics Co., Ltd. Treating auto-immune and auto-inflammatory diseases
US10231976B2 (en) * 2010-02-08 2019-03-19 Prairie Pharmaceuticals LLC Methods for the use of progestogen as a glucocorticoid sensitizer
WO2012027222A1 (en) 2010-08-24 2012-03-01 Rutgers, The State University Of New Jersey Formulation and manufacture of pharmaceuticals by impregnation onto porous carriers
AU2012307656B2 (en) * 2011-09-15 2016-07-07 Friulchem Spa Compositions for oral administration to animals, production methods thereof and uses of same
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
EP2782584B1 (en) 2011-11-23 2021-06-09 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
JP2013169146A (ja) * 2012-02-17 2013-09-02 Kabaya Shokuhin Kk 新規清涼菓子およびその製造方法
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2014120922A1 (en) * 2013-02-01 2014-08-07 W. R. Grace & Co.-Conn. Porous silica gel as a carrier for liquid technologies
LT2953617T (lt) 2013-02-06 2020-01-10 Hermes Arzneimittel Gmbh Farmacinės kompozicijos, apimančios mažų dozių vaistus
AR100562A1 (es) 2014-05-22 2016-10-12 Therapeuticsmd Inc Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal
HUE051900T2 (hu) 2014-06-20 2021-03-29 Hermes Arzneimittel Gmbh Íz-leplezett orális gyógyászati készítmény
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017081725A1 (ja) * 2015-11-09 2017-05-18 花王株式会社 口腔用組成物
CN105456203B (zh) * 2015-12-11 2018-05-15 中国人民解放军63975部队 一种药物-载体模式复合微粉制备方法
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
KR102524880B1 (ko) * 2017-12-21 2023-04-21 한양대학교 산학협력단 하이드로콜로이드 조성물 및 이를 포함하는 바이오 패치
CN109123285A (zh) * 2018-08-27 2019-01-04 上海戚熊实业有限公司 一种太岁浸渍工艺制备的饮用水
EP4072516A1 (en) 2019-12-09 2022-10-19 Nicoventures Trading Limited Oral product comprising a cannabinoid
EP4076501A4 (en) 2019-12-16 2024-05-08 Rutgers, the State University of New Jersey CONTINUOUS PROCESSES FOR MANUFACTURING IMPREGNATED POROUS SUPPORTS AND FOR MANUFACTURING IMPREGNATED POROUS SUPPORTS CONTAINING PHARMACEUTICAL PRODUCTS
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
WO2023214018A1 (en) 2022-05-06 2023-11-09 Galenix Innovations Gastro-retentive swellable sustained release composition
KR102726949B1 (ko) * 2023-12-22 2024-11-06 대가파우더시스템 주식회사 유연성 고체형 지혈제 조성물, 유연성 고체형 지혈제 및 이의 제조방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1468815A (en) * 1973-10-18 1977-03-30 Vymatt Sa Pharmaceutical compositions
GB8822857D0 (en) * 1988-09-29 1988-11-02 Patralan Ltd Pharmaceutical formulations
IT1291362B1 (it) * 1997-05-13 1999-01-07 Vectorpharma Int Composizioni farmaceutiche multicomponente bifasiche contenenti sostanze atte a modificare la partizione dei principi attivi
JP2000026283A (ja) * 1998-07-10 2000-01-25 Nisshin Oil Mills Ltd:The 油性組成物を含有した粉末組成物
JP4815053B2 (ja) * 1998-08-13 2011-11-16 シーマ・ラブス、インコーポレイテッド 経口投与の固形投与形態物としてのマイクロエマルション
US6267985B1 (en) * 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions
WO2002083102A1 (en) * 2001-02-23 2002-10-24 Cima Labs Inc. Emulsions as solid dosage forms for oral administration
ITMI20011756A1 (it) * 2001-08-09 2003-02-09 Remedia S R L Composizione farmaceutica comprendente una microemulsione doppia acqua/olio/acqua incorporata in un supporto solido
ITMI20012694A1 (it) * 2001-12-19 2003-06-19 Remedia S R L Composizione farmaceutica comprendente una microemulsione doppia olio/acqua/olio incorporata in un supporto solido

Also Published As

Publication number Publication date
EP1603538A2 (fr) 2005-12-14
CA2518200A1 (fr) 2004-09-23
RU2367412C2 (ru) 2009-09-20
MXPA05009440A (es) 2006-04-07
NO20054562D0 (no) 2005-10-04
WO2004080381A3 (fr) 2005-07-28
FR2851918B1 (fr) 2006-06-16
NO20054562L (no) 2005-12-01
US7569274B2 (en) 2009-08-04
JP2006519820A (ja) 2006-08-31
AU2004218859A1 (en) 2004-09-23
RU2005130989A (ru) 2006-08-10
AU2004218859B2 (en) 2009-10-15
CA2518200C (fr) 2013-04-30
FR2851918A1 (fr) 2004-09-10
US20060182691A1 (en) 2006-08-17
WO2004080381A2 (fr) 2004-09-23
JP4901469B2 (ja) 2012-03-21

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