JP4901469B2 - 生物学的利用能および/または溶解度を増大させるための含浸粉末とその製造方法 - Google Patents
生物学的利用能および/または溶解度を増大させるための含浸粉末とその製造方法 Download PDFInfo
- Publication number
- JP4901469B2 JP4901469B2 JP2006505704A JP2006505704A JP4901469B2 JP 4901469 B2 JP4901469 B2 JP 4901469B2 JP 2006505704 A JP2006505704 A JP 2006505704A JP 2006505704 A JP2006505704 A JP 2006505704A JP 4901469 B2 JP4901469 B2 JP 4901469B2
- Authority
- JP
- Japan
- Prior art keywords
- impregnated powder
- active ingredient
- liquid medium
- impregnated
- tablets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
- Y10T428/2993—Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
- Y10T428/2993—Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
- Y10T428/2995—Silane, siloxane or silicone coating
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
- Y10T428/2993—Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
- Y10T428/2996—Glass particles or spheres
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
- Y10T428/2998—Coated including synthetic resin or polymer
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- General Preparation And Processing Of Foods (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0302802A FR2851918B1 (fr) | 2003-03-06 | 2003-03-06 | Poudre impregnee ameliorant la biodisponibilite et/ou la solubilite et procede de fabrication |
| FR03/02802 | 2003-03-06 | ||
| PCT/FR2004/000541 WO2004080381A2 (fr) | 2003-03-06 | 2004-03-05 | Poudre impregnee ameliorant la biodisponibilite et/ou la solubilite et procede de fabrication |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006519820A JP2006519820A (ja) | 2006-08-31 |
| JP4901469B2 true JP4901469B2 (ja) | 2012-03-21 |
Family
ID=32865308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006505704A Expired - Fee Related JP4901469B2 (ja) | 2003-03-06 | 2004-03-05 | 生物学的利用能および/または溶解度を増大させるための含浸粉末とその製造方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7569274B2 (pt) |
| EP (1) | EP1603538A2 (pt) |
| JP (1) | JP4901469B2 (pt) |
| AU (1) | AU2004218859B2 (pt) |
| BR (1) | BRPI0408065A (pt) |
| CA (1) | CA2518200C (pt) |
| FR (1) | FR2851918B1 (pt) |
| MX (1) | MXPA05009440A (pt) |
| NO (1) | NO20054562L (pt) |
| RU (1) | RU2367412C2 (pt) |
| WO (1) | WO2004080381A2 (pt) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY142989A (en) * | 2004-03-10 | 2011-02-14 | Bayer Schering Pharma Ag | Stabilised supersaturated solids of lipophilic drugs |
| CA2598762A1 (en) * | 2005-02-25 | 2006-08-31 | F. Hoffmann-La Roche Ag | Tablets with improved drug substance dispersibility |
| EP1893182B8 (en) | 2005-05-26 | 2012-04-04 | Teva Women's Health, Inc. | Oral dosage forms comprising progesterone and method of making and using the same |
| RU2309732C1 (ru) | 2006-03-13 | 2007-11-10 | Олег Ильич Эпштейн | Спрессованная твердая оральная форма лекарственного препарата и способ получения твердой оральной формы лекарственного препарата |
| US20080160097A1 (en) * | 2006-12-28 | 2008-07-03 | Avon Products, Inc. | Method for imparting a cosmetic or therapeutic benefit to a topical surface and process for making |
| PT3150586T (pt) | 2007-02-23 | 2020-03-31 | Gilead Sciences Inc | Moduladores de propriedades farmacocinéticas de agentes terapêuticos |
| WO2008104852A2 (en) * | 2007-02-26 | 2008-09-04 | Wockhardt Research Centre | Pharmaceutical compositions comprising adsorbate of fenofibrate |
| AU2008275937A1 (en) * | 2007-07-19 | 2009-01-22 | Luzenac America, Inc. | Silicone coatings, methods of making silicone coated articles and coated articles therefrom |
| US10531681B2 (en) | 2008-04-25 | 2020-01-14 | Sensient Colors Llc | Heat-triggered colorants and methods of making and using the same |
| EA201591353A1 (ru) | 2008-05-02 | 2016-01-29 | Джилид Сайэнс, Инк. | Применение частиц твердого носителя для улучшения технологических характеристик фармацевтического агента |
| US20090298952A1 (en) * | 2008-05-07 | 2009-12-03 | Brimmer Karen S | Platable soluble dyes |
| US9113647B2 (en) | 2008-08-29 | 2015-08-25 | Sensient Colors Llc | Flavored and edible colored waxes and methods for precision deposition on edible substrates |
| US20100102142A1 (en) * | 2008-10-28 | 2010-04-29 | Daria Tagliareni | Scent dispenser assembly |
| RU2448684C2 (ru) * | 2009-01-15 | 2012-04-27 | Федеральное бюджетное учреждение науки "Московский научно-исследовательский институт эпидемиологии и микробиологии им. Г.Н. Габричевского" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН "МНИИЭМ им. Г.Н. Габричевского" Роспотребнадзора) | Препарат, содержащий биологически активные действующие вещества |
| KR100926952B1 (ko) | 2009-06-04 | 2009-11-17 | 화인케미칼 주식회사 | 고분자 컴파운드용 오일함유 파우더 |
| US11052029B2 (en) * | 2009-06-16 | 2021-07-06 | W. R. Grace & Co.-Conn. | Cation compatible metal oxides and oral care compositions containing the metal oxides |
| US11000711B2 (en) | 2009-12-29 | 2021-05-11 | W. R. Grace & Co.-Conn. | Compositions for forming films having a desired degree of obscuration and methods of making and using the same |
| US10993879B2 (en) | 2010-02-08 | 2021-05-04 | Shenzhen Evergreen Therapeutics Co., Ltd. | Pulmonary delivery of progestogen |
| US10987361B2 (en) | 2010-02-08 | 2021-04-27 | Shenzhen Evergreen Therapeutics Co., Ltd. | Treating auto-immune and auto-inflammatory diseases |
| US10231976B2 (en) * | 2010-02-08 | 2019-03-19 | Prairie Pharmaceuticals LLC | Methods for the use of progestogen as a glucocorticoid sensitizer |
| WO2012027222A1 (en) | 2010-08-24 | 2012-03-01 | Rutgers, The State University Of New Jersey | Formulation and manufacture of pharmaceuticals by impregnation onto porous carriers |
| AU2012307656B2 (en) * | 2011-09-15 | 2016-07-07 | Friulchem Spa | Compositions for oral administration to animals, production methods thereof and uses of same |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| EP2782584B1 (en) | 2011-11-23 | 2021-06-09 | TherapeuticsMD, Inc. | Natural combination hormone replacement formulations and therapies |
| JP2013169146A (ja) * | 2012-02-17 | 2013-09-02 | Kabaya Shokuhin Kk | 新規清涼菓子およびその製造方法 |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| WO2014120922A1 (en) * | 2013-02-01 | 2014-08-07 | W. R. Grace & Co.-Conn. | Porous silica gel as a carrier for liquid technologies |
| LT2953617T (lt) | 2013-02-06 | 2020-01-10 | Hermes Arzneimittel Gmbh | Farmacinės kompozicijos, apimančios mažų dozių vaistus |
| AR100562A1 (es) | 2014-05-22 | 2016-10-12 | Therapeuticsmd Inc | Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal |
| HUE051900T2 (hu) | 2014-06-20 | 2021-03-29 | Hermes Arzneimittel Gmbh | Íz-leplezett orális gyógyászati készítmény |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| WO2017081725A1 (ja) * | 2015-11-09 | 2017-05-18 | 花王株式会社 | 口腔用組成物 |
| CN105456203B (zh) * | 2015-12-11 | 2018-05-15 | 中国人民解放军63975部队 | 一种药物-载体模式复合微粉制备方法 |
| KR20180126582A (ko) | 2016-04-01 | 2018-11-27 | 쎄러퓨틱스엠디, 인코퍼레이티드 | 스테로이드 호르몬 약제학적 조성물 |
| WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
| KR102524880B1 (ko) * | 2017-12-21 | 2023-04-21 | 한양대학교 산학협력단 | 하이드로콜로이드 조성물 및 이를 포함하는 바이오 패치 |
| CN109123285A (zh) * | 2018-08-27 | 2019-01-04 | 上海戚熊实业有限公司 | 一种太岁浸渍工艺制备的饮用水 |
| EP4072516A1 (en) | 2019-12-09 | 2022-10-19 | Nicoventures Trading Limited | Oral product comprising a cannabinoid |
| EP4076501A4 (en) | 2019-12-16 | 2024-05-08 | Rutgers, the State University of New Jersey | CONTINUOUS PROCESSES FOR MANUFACTURING IMPREGNATED POROUS SUPPORTS AND FOR MANUFACTURING IMPREGNATED POROUS SUPPORTS CONTAINING PHARMACEUTICAL PRODUCTS |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
| WO2023214018A1 (en) | 2022-05-06 | 2023-11-09 | Galenix Innovations | Gastro-retentive swellable sustained release composition |
| KR102726949B1 (ko) * | 2023-12-22 | 2024-11-06 | 대가파우더시스템 주식회사 | 유연성 고체형 지혈제 조성물, 유연성 고체형 지혈제 및 이의 제조방법 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1468815A (en) * | 1973-10-18 | 1977-03-30 | Vymatt Sa | Pharmaceutical compositions |
| GB8822857D0 (en) * | 1988-09-29 | 1988-11-02 | Patralan Ltd | Pharmaceutical formulations |
| IT1291362B1 (it) * | 1997-05-13 | 1999-01-07 | Vectorpharma Int | Composizioni farmaceutiche multicomponente bifasiche contenenti sostanze atte a modificare la partizione dei principi attivi |
| JP2000026283A (ja) * | 1998-07-10 | 2000-01-25 | Nisshin Oil Mills Ltd:The | 油性組成物を含有した粉末組成物 |
| JP4815053B2 (ja) * | 1998-08-13 | 2011-11-16 | シーマ・ラブス、インコーポレイテッド | 経口投与の固形投与形態物としてのマイクロエマルション |
| US6267985B1 (en) * | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| WO2002083102A1 (en) * | 2001-02-23 | 2002-10-24 | Cima Labs Inc. | Emulsions as solid dosage forms for oral administration |
| ITMI20011756A1 (it) * | 2001-08-09 | 2003-02-09 | Remedia S R L | Composizione farmaceutica comprendente una microemulsione doppia acqua/olio/acqua incorporata in un supporto solido |
| ITMI20012694A1 (it) * | 2001-12-19 | 2003-06-19 | Remedia S R L | Composizione farmaceutica comprendente una microemulsione doppia olio/acqua/olio incorporata in un supporto solido |
-
2003
- 2003-03-06 FR FR0302802A patent/FR2851918B1/fr not_active Expired - Fee Related
-
2004
- 2004-03-05 CA CA2518200A patent/CA2518200C/fr not_active Expired - Fee Related
- 2004-03-05 EP EP04717669A patent/EP1603538A2/fr not_active Withdrawn
- 2004-03-05 US US10/547,797 patent/US7569274B2/en not_active Expired - Fee Related
- 2004-03-05 BR BRPI0408065-3A patent/BRPI0408065A/pt not_active IP Right Cessation
- 2004-03-05 MX MXPA05009440A patent/MXPA05009440A/es active IP Right Grant
- 2004-03-05 AU AU2004218859A patent/AU2004218859B2/en not_active Ceased
- 2004-03-05 RU RU2005130989/15A patent/RU2367412C2/ru not_active IP Right Cessation
- 2004-03-05 WO PCT/FR2004/000541 patent/WO2004080381A2/fr not_active Ceased
- 2004-03-05 JP JP2006505704A patent/JP4901469B2/ja not_active Expired - Fee Related
-
2005
- 2005-10-04 NO NO20054562A patent/NO20054562L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1603538A2 (fr) | 2005-12-14 |
| CA2518200A1 (fr) | 2004-09-23 |
| BRPI0408065A (pt) | 2006-02-14 |
| RU2367412C2 (ru) | 2009-09-20 |
| MXPA05009440A (es) | 2006-04-07 |
| NO20054562D0 (no) | 2005-10-04 |
| WO2004080381A3 (fr) | 2005-07-28 |
| FR2851918B1 (fr) | 2006-06-16 |
| NO20054562L (no) | 2005-12-01 |
| US7569274B2 (en) | 2009-08-04 |
| JP2006519820A (ja) | 2006-08-31 |
| AU2004218859A1 (en) | 2004-09-23 |
| RU2005130989A (ru) | 2006-08-10 |
| AU2004218859B2 (en) | 2009-10-15 |
| CA2518200C (fr) | 2013-04-30 |
| FR2851918A1 (fr) | 2004-09-10 |
| US20060182691A1 (en) | 2006-08-17 |
| WO2004080381A2 (fr) | 2004-09-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006519820A (ja) | 生物学的利用能および/または溶解度を増大させるための含浸粉末とその製造方法 | |
| JP4815053B2 (ja) | 経口投与の固形投与形態物としてのマイクロエマルション | |
| US7374779B2 (en) | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents | |
| JP6861679B2 (ja) | 液体テクノロジーのための担体としての多孔質シリカゲル | |
| JP2006511536A (ja) | 水貧溶性薬物のバイオアベイラビリティーを改善する自由流動性固形製剤およびその製造方法 | |
| CN110721164B (zh) | 匹莫苯的改善的药物组合物 | |
| CN112888429A (zh) | 大麻素的多颗粒配方 | |
| Zhou et al. | Preparation of tripterine nanostructured lipid carriers and their absorption in rat intestine | |
| FR2841138A1 (fr) | Composition pharmaceutique solide contenant un principe actif lipophile, son procede de preparation | |
| JP2002522473A5 (pt) | ||
| WO2009092291A1 (zh) | 一种给药系统及其制备方法和应用 | |
| KR20070046913A (ko) | 비층상 분산을 형성하는 조성물 | |
| CN105007898A (zh) | 难溶性药物的过饱和的稳定纳米颗粒 | |
| CN112353845B (zh) | 含中药挥发油的热熔挤出组合物及其制备方法和药物制剂 | |
| EP1893176A1 (de) | Herstellung von festen lösungen schwerlöslicher wirkstoffe durch kurzzeitüberhitzung und schnelle trocknung | |
| TW200840596A (en) | Microemulsion dosage forms of valsartan and methods of making the same | |
| WO2002083099A1 (de) | Pharmazeutische formulierungen enthaltend entzündungshemmende wirkstoffe und deren verwendung | |
| EP4045143B1 (en) | Bosentan monohydrate loaded liquid self nanoemulsifying drug carrier system and tablet formulation | |
| JP2009544578A (ja) | コロイド状二酸化ケイ素を含むペレット製剤 | |
| MX2007007887A (es) | Sistema galenico novedoso para transporte del principio activo, metodo de preparacion y uso. | |
| CN101340882A (zh) | 含有药物的蜡基质粒子的制造方法、用于该方法的挤出机、及含有西洛他唑的缓释制剂 | |
| JP5684440B2 (ja) | 組成物および固形製剤 | |
| CN102697764A (zh) | 一种含有异硫氰酸苯乙酯的肠溶固体制剂 | |
| Ibrahim et al. | Self-emulsifying drug delivery formulations | |
| JP2004518679A (ja) | リポイドビヒクルに分散させたサムパトリラートを含む薬学的組成物 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20070219 |
|
| RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20090331 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20100713 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20101013 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20101020 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20110113 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20110405 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20110805 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20110921 |
|
| A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20111026 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20111206 |
|
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20111227 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20150113 Year of fee payment: 3 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |