BRPI0408092A - processo para preparar composto, e, composto - Google Patents

processo para preparar composto, e, composto

Info

Publication number
BRPI0408092A
BRPI0408092A BRPI0408092-0A BRPI0408092A BRPI0408092A BR PI0408092 A BRPI0408092 A BR PI0408092A BR PI0408092 A BRPI0408092 A BR PI0408092A BR PI0408092 A BRPI0408092 A BR PI0408092A
Authority
BR
Brazil
Prior art keywords
compost
preparing
steps
present
aminomethyl
Prior art date
Application number
BRPI0408092-0A
Other languages
English (en)
Inventor
Gyo Hyun Hwang
Yeong Dae Kim
Hyun Nam
Jay Hyok Chang
Hyun Ik Shin
Young Keun Kim
Kyung Hee Lee
Jae Sung Lee
Hyun Kuk Noh
Original Assignee
Lg Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd
Publication of BRPI0408092A publication Critical patent/BRPI0408092A/pt
Publication of BRPI0408092B1 publication Critical patent/BRPI0408092B1/pt
Publication of BRPI0408092B8 publication Critical patent/BRPI0408092B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B43—WRITING OR DRAWING IMPLEMENTS; BUREAU ACCESSORIES
    • B43K—IMPLEMENTS FOR WRITING OR DRAWING
    • B43K27/00—Multiple-point writing implements, e.g. multicolour; Combinations of writing implements
    • B43K27/08—Combinations of pens
    • B43K27/12—Combinations of pens of ball-point pens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B43—WRITING OR DRAWING IMPLEMENTS; BUREAU ACCESSORIES
    • B43K—IMPLEMENTS FOR WRITING OR DRAWING
    • B43K23/00—Holders or connectors for writing implements; Means for protecting the writing-points
    • B43K23/08—Protecting means, e.g. caps
    • B43K23/12—Protecting means, e.g. caps for pens
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B43—WRITING OR DRAWING IMPLEMENTS; BUREAU ACCESSORIES
    • B43K—IMPLEMENTS FOR WRITING OR DRAWING
    • B43K27/00—Multiple-point writing implements, e.g. multicolour; Combinations of writing implements
    • B43K27/006—Pen or pencil barrels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B43—WRITING OR DRAWING IMPLEMENTS; BUREAU ACCESSORIES
    • B43K—IMPLEMENTS FOR WRITING OR DRAWING
    • B43K7/00—Ball-point pens
    • B43K7/005—Pen barrels
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Fertilizers (AREA)

Abstract

"PROCESSO PARA PREPARAR COMPOSTO, E, COMPOSTO". A presente invenção se refere a um processo para preparar metanosulfonato de 4-aminometil-3-alcoximinopirrolidina, uma chave intermediária de antibióticos de quinolona. De acordo com o processo da presente invenção, o número total de etapas tem sido diminuído para 2 a 3 etapas, a separação sólida não é requerida, e o uso de produtos químicos caros, particularmente (BOC)20 (anidrido de t-butoxicarbonila), vários solventes e reagentes orgânicos, é eliminado.
BRPI0408092A 2003-03-07 2004-03-06 processo para preparar composto, e, composto BRPI0408092B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20030014469 2003-03-07
PCT/KR2004/000476 WO2004092129A1 (en) 2003-03-07 2004-03-06 New process for preparing 4-aminomethyl-3-alkoxyiminopyrrolidine methanesulfonate

Publications (3)

Publication Number Publication Date
BRPI0408092A true BRPI0408092A (pt) 2006-02-14
BRPI0408092B1 BRPI0408092B1 (pt) 2016-12-27
BRPI0408092B8 BRPI0408092B8 (pt) 2021-05-25

Family

ID=36114240

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408092A BRPI0408092B8 (pt) 2003-03-07 2004-03-06 processo para preparar composto, e, composto

Country Status (18)

Country Link
US (2) US7271272B2 (pt)
EP (1) EP1603875B1 (pt)
JP (1) JP4558709B2 (pt)
KR (2) KR100653334B1 (pt)
CN (1) CN100366608C (pt)
AT (1) ATE525352T1 (pt)
BR (1) BRPI0408092B8 (pt)
CA (1) CA2518081C (pt)
ES (1) ES2373717T3 (pt)
MX (1) MXPA05009476A (pt)
NO (1) NO330470B1 (pt)
NZ (1) NZ542268A (pt)
PL (1) PL1603875T3 (pt)
PT (1) PT1603875E (pt)
RU (1) RU2303029C2 (pt)
UA (1) UA82504C2 (pt)
WO (1) WO2004092129A1 (pt)
ZA (1) ZA200507141B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030181488A1 (en) 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
US20040105413A1 (en) * 2002-07-02 2004-06-03 Interdigital Technology Corporation System and method for tight inter-working between wireless local area network (WLAN) and universal mobile telecommunication systems (UMTS)
KR100653334B1 (ko) * 2003-03-07 2006-12-04 주식회사 엘지생명과학 4-아미노메틸-3-알콕시이미노피롤리딘 메탄설폰산염의 신규한 제조 방법
WO2007068002A2 (en) * 2005-12-09 2007-06-14 Tego Inc. Multiple radio frequency network node rfid tag
US8277872B1 (en) * 2008-11-12 2012-10-02 Stc.Unm Methods of making multi-scale carbon structures
CN104693088B (zh) * 2013-12-06 2018-01-05 常州市勇毅生物药业有限公司 一种吉米沙星侧链的制备方法
CN113773240B (zh) * 2021-10-12 2022-05-31 北京阳光诺和药物研究股份有限公司 吉米沙星侧链化合物的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3309368A (en) * 1965-11-19 1967-03-14 American Cyanamid Co Substituted isoxazoles and methods of preparing the same
US3562287A (en) * 1968-03-06 1971-02-09 American Cyanamid Co Ethyl 3-(n-substituted-acetimidoylamino) -4-hpyrrolo(3,4-c)isoxazole-5(6h)-carboxylates
CS274601B2 (en) * 1983-07-27 1991-09-15 Dainippon Pharmaceutical Co Method of 1,8-naphthyridine derivative production
US5776944A (en) * 1994-06-16 1998-07-07 Lg Chemical Ltd. 7-(4-aminomethyl-3-methyloxyiminopyrroplidin-1-yl)-1-cyclopropyl-6-flu oro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof
DE69509442T2 (de) * 1994-06-16 1999-09-02 Lg Chemical Ltd. Chinolincarbonsäurederivate mit 7-(4-Amino-methyl-3-oxim)-pyrrolidin-Substituenten und Verfahren zu ihrer Herstellung
IT234996Y1 (it) 1994-06-22 2000-03-31 Bocchiotti Soc Ind Elettrotec Imballaggio per profilati metallici.
KR100241673B1 (ko) * 1997-08-09 2000-03-02 김충섭 퀴놀리진 카르복실산 유도체
KR100286874B1 (ko) 1998-03-04 2001-04-16 성재갑 보호된 4-아미노메틸-피롤리딘-3-온의 제조방법
GB9920917D0 (en) * 1999-09-03 1999-11-10 Sb Pharmco Inc Novel process
GB9920919D0 (en) * 1999-09-03 1999-11-10 Sb Pharmco Inc Novel compound
KR20010091379A (ko) * 2000-03-15 2001-10-23 성재갑 7-(4-아미노메틸-3-옥심)피롤리딘 치환체를 갖는 퀴놀린카르복실산 유도체의 신규 제조방법
KR20020018560A (ko) * 2000-09-01 2002-03-08 성재갑 3-아미노메틸-4-ｚ-메톡시이미노피롤리딘의 신규 제조방법
JP2005500350A (ja) * 2001-08-02 2005-01-06 エルジー ライフサイエンス リミテッド ４−アミノメチレン−ピロリジン−３−オンおよび／または４−アミノメチレン−ピロリジン−３−アルコキシイミノ誘導体のアミノ保護誘導体、および／またはジェミフロキサシンまたはその塩の製造方法
KR100653334B1 (ko) * 2003-03-07 2006-12-04 주식회사 엘지생명과학 4-아미노메틸-3-알콕시이미노피롤리딘 메탄설폰산염의 신규한 제조 방법

Also Published As

Publication number Publication date
CA2518081C (en) 2010-05-04
NO20054541L (no) 2005-10-03
CN1759100A (zh) 2006-04-12
US7271272B2 (en) 2007-09-18
ES2373717T3 (es) 2012-02-08
EP1603875A1 (en) 2005-12-14
US20070282107A1 (en) 2007-12-06
US20060173195A1 (en) 2006-08-03
RU2303029C2 (ru) 2007-07-20
WO2004092129A1 (en) 2004-10-28
PT1603875E (pt) 2011-11-28
BRPI0408092B8 (pt) 2021-05-25
CN100366608C (zh) 2008-02-06
MXPA05009476A (es) 2005-11-23
NZ542268A (en) 2008-03-28
EP1603875A4 (en) 2008-11-19
CA2518081A1 (en) 2004-10-28
PL1603875T3 (pl) 2011-12-30
UA82504C2 (uk) 2008-04-25
RU2005127868A (ru) 2006-02-27
ZA200507141B (en) 2006-05-31
KR100653334B1 (ko) 2006-12-04
JP4558709B2 (ja) 2010-10-06
JP2006515371A (ja) 2006-05-25
US7687629B2 (en) 2010-03-30
NO330470B1 (no) 2011-04-18
ATE525352T1 (de) 2011-10-15
EP1603875B1 (en) 2011-09-21
KR100691735B1 (ko) 2007-03-12
KR20040079324A (ko) 2004-09-14
KR20060059942A (ko) 2006-06-02
BRPI0408092B1 (pt) 2016-12-27

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: "PARA: INT. CL. C07D 207/22

Ipc: C07D 207/22 (2011.01), A61P 31/00 (2011.01)

Free format text: PARA: INT. CL. C07D 207/22; A61P 31/00

Ipc: C07D 207/22 (2011.01), A61P 31/00 (2011.01)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 27/12/2016, OBSERVADAS AS CONDICOES LEGAIS.

B25G Requested change of headquarter approved
B25G Requested change of headquarter approved
B25A Requested transfer of rights approved
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 06/03/2004 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

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B21H Decision of lapse of a patent or of a certificate of addition of invention cancelled [chapter 21.8 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 21.6 NA RPI NO 2822 DE 04/02/2025 POR TER SIDO INDEVIDA.