ATE428677T1 - Rückgewinnung und recycling chiraler weinsäureverbindungen zur racematspaltung - Google Patents

Rückgewinnung und recycling chiraler weinsäureverbindungen zur racematspaltung

Info

Publication number
ATE428677T1
ATE428677T1 AT02803000T AT02803000T ATE428677T1 AT E428677 T1 ATE428677 T1 AT E428677T1 AT 02803000 T AT02803000 T AT 02803000T AT 02803000 T AT02803000 T AT 02803000T AT E428677 T1 ATE428677 T1 AT E428677T1
Authority
AT
Austria
Prior art keywords
recovery
racemat
chiral
recycling
deviation
Prior art date
Application number
AT02803000T
Other languages
English (en)
Inventor
Steve Martin
Daniele Piergentili
Original Assignee
Aesica Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aesica Pharmaceuticals Ltd filed Critical Aesica Pharmaceuticals Ltd
Application granted granted Critical
Publication of ATE428677T1 publication Critical patent/ATE428677T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00Separation of optically-active compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • C07C67/52Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • C07C67/60Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02803000T 2001-11-14 2002-11-08 Rückgewinnung und recycling chiraler weinsäureverbindungen zur racematspaltung ATE428677T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0127346A GB2382074A (en) 2001-11-14 2001-11-14 Recovery of chiral tartaric acid resolving agents
PCT/EP2002/012494 WO2003042132A1 (en) 2001-11-14 2002-11-08 Recovery and recycling of chiral tartaric acid resolving agents

Publications (1)

Publication Number Publication Date
ATE428677T1 true ATE428677T1 (de) 2009-05-15

Family

ID=9925776

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02803000T ATE428677T1 (de) 2001-11-14 2002-11-08 Rückgewinnung und recycling chiraler weinsäureverbindungen zur racematspaltung

Country Status (11)

Country Link
US (1) US7838700B2 (de)
EP (1) EP1446372B1 (de)
JP (1) JP2005509011A (de)
AT (1) ATE428677T1 (de)
CA (1) CA2465294A1 (de)
DE (1) DE60232006D1 (de)
ES (1) ES2324772T3 (de)
GB (1) GB2382074A (de)
HU (1) HUP0402368A3 (de)
IL (2) IL161540A0 (de)
WO (1) WO2003042132A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7358384B2 (en) 2003-01-16 2008-04-15 Toray Fine Chemicals Co., Ltd. Processes for the recovery of optically active diacyltartaric acids
ES2264378B1 (es) * 2005-05-09 2007-11-01 Ragactives, S.L. Procedimiento para la resolucion de 2-amino-6propilamino-4,5,6,7-tetrahidrobenzotiazol y compuestos intermedios.
EP1736462A1 (de) * 2005-06-22 2006-12-27 Sandoz AG Rückgewinnung optisch aktiver Weinsäurederivate als Racematspaltungsmittel
MD4504C1 (ro) * 2016-04-13 2018-03-31 Общественное Учреждение "Научно-Практический Институт Садоводства И Пищевых Технологий" Procedeu de obţinere a acidului tartric din tartratul de calciu obţinut din deşeuri vinicole
JP7516029B2 (ja) 2018-11-16 2024-07-16 アムジエン・インコーポレーテツド Kras g12c阻害剤化合物の重要な中間体の改良合成法
CN116323611A (zh) * 2020-10-07 2023-06-23 美国安进公司 使7-氯-6-氟-1-(2-异丙基-4-甲基吡啶-3-基)吡啶并[2,3-d]嘧啶-2,4(1h,3h)-二酮的阻转异构体外消旋和分离的方法
CN112358398A (zh) * 2020-11-19 2021-02-12 山东新华制药股份有限公司 D-(+)-二对甲苯甲酰酒石酸的回收制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09176115A (ja) * 1995-12-28 1997-07-08 Koei Chem Co Ltd 光学活性なn−ベンジル−3−アミノピロリジンの製造方法
HU221921B1 (hu) 1996-07-08 2003-02-28 Richter Gedeon Vegyészeti Gyár Rt. N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására
CN1173929C (zh) * 1999-10-19 2004-11-03 中国科学院成都有机化学研究所 光学纯肾上腺素类β-激动剂的组合拆分制备法
GB9930577D0 (en) 1999-12-23 2000-02-16 Smithkline Beecham Plc Novel process

Also Published As

Publication number Publication date
IL161540A (en) 2011-03-31
JP2005509011A (ja) 2005-04-07
CA2465294A1 (en) 2003-05-22
US20050085665A1 (en) 2005-04-21
EP1446372B1 (de) 2009-04-15
IL161540A0 (en) 2004-09-27
ES2324772T3 (es) 2009-08-14
HUP0402368A3 (en) 2008-02-28
HUP0402368A2 (hu) 2005-03-29
DE60232006D1 (de) 2009-05-28
EP1446372A1 (de) 2004-08-18
WO2003042132A1 (en) 2003-05-22
US7838700B2 (en) 2010-11-23
GB2382074A (en) 2003-05-21
GB0127346D0 (en) 2002-01-02

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