BRPI0408117A - compostos heterocìclicos bifuncionais e métodos de produção e uso dos mesmos - Google Patents

compostos heterocìclicos bifuncionais e métodos de produção e uso dos mesmos

Info

Publication number
BRPI0408117A
BRPI0408117A BRPI0408117-0A BRPI0408117A BRPI0408117A BR PI0408117 A BRPI0408117 A BR PI0408117A BR PI0408117 A BRPI0408117 A BR PI0408117A BR PI0408117 A BRPI0408117 A BR PI0408117A
Authority
BR
Brazil
Prior art keywords
methods
heterocyclic compounds
production
bifunctional heterocyclic
bifunctional
Prior art date
Application number
BRPI0408117-0A
Other languages
English (en)
Inventor
Jay J Farmer
Joyce A Sutcliffe
Ashoke Bhattacharjee
Original Assignee
Rib X Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rib X Pharmaceuticals Inc filed Critical Rib X Pharmaceuticals Inc
Publication of BRPI0408117A publication Critical patent/BRPI0408117A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

"COMPOSTOS HETEROCìCLICOS BIFUNCIONAIS E MéTODOS DE PRODUçãO E USO DOS MESMOS". A invenção refere-se a uma família de compostos heterocíclicos bifuncionais úteis como agentes antiinfecciosos, antiproliferativos, antiinflamatórios e procinéticos. A invenção também fornece métodos para produzir os compostos heterocíclicos bifuncionais, e métodos de uso de tais compostos como agentes antiinfecciosos, antiproliferativos, antiinflamatórios e/ou procinéticos.
BRPI0408117-0A 2003-03-05 2004-03-05 compostos heterocìclicos bifuncionais e métodos de produção e uso dos mesmos BRPI0408117A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45195103P 2003-03-05 2003-03-05
PCT/US2004/006892 WO2004078770A1 (en) 2003-03-05 2004-03-05 Bifunctional heterocyclic compounds and methods of making and using the same

Publications (1)

Publication Number Publication Date
BRPI0408117A true BRPI0408117A (pt) 2006-03-01

Family

ID=32962667

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408117-0A BRPI0408117A (pt) 2003-03-05 2004-03-05 compostos heterocìclicos bifuncionais e métodos de produção e uso dos mesmos

Country Status (11)

Country Link
US (1) US20070072811A1 (pt)
EP (1) EP1599491A1 (pt)
JP (1) JP2006523229A (pt)
KR (1) KR20060002800A (pt)
CN (1) CN1780846A (pt)
AU (1) AU2004217919A1 (pt)
BR (1) BRPI0408117A (pt)
CA (1) CA2517970A1 (pt)
MX (1) MXPA05009430A (pt)
NO (1) NO20054535L (pt)
WO (1) WO2004078770A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091196B2 (en) 2002-09-26 2006-08-15 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using same
WO2005042554A1 (en) * 2003-10-30 2005-05-12 Rib-X Pharmaceuticals, Inc. Bifunctional macrolide heterocyclic compounds and methods of making and using the same
JP2007512256A (ja) * 2003-11-18 2007-05-17 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法
EP2716647A3 (en) 2004-02-27 2014-08-20 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
EP1928893A2 (en) 2005-08-24 2008-06-11 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
BRPI0617824A2 (pt) 2005-10-28 2011-08-09 Nestec Sa métodos para o uso de aminoácidos de cadeia ramificada
JPWO2009019868A1 (ja) 2007-08-06 2010-10-28 大正製薬株式会社 １０ａ、１２位架橋型１０ａ−アザライド化合物
WO2009139181A1 (ja) 2008-05-15 2009-11-19 大正製薬株式会社 ４員環構造を有する１０ａ－アザライド化合物
US8765735B2 (en) 2009-05-18 2014-07-01 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
US9149465B2 (en) 2009-05-18 2015-10-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
US8927551B2 (en) 2009-05-18 2015-01-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
CN101857617A (zh) * 2010-04-28 2010-10-13 中国海洋大学 喹唑啉类糖衍生物及其制备方法和应用
CA2967825A1 (en) 2014-11-14 2016-05-19 Melinta Therapeutics, Inc. Method for treating, preventing, or reducing the risk of skin infection

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Also Published As

Publication number Publication date
KR20060002800A (ko) 2006-01-09
EP1599491A1 (en) 2005-11-30
WO2004078770A1 (en) 2004-09-16
CN1780846A (zh) 2006-05-31
MXPA05009430A (es) 2006-04-07
NO20054535L (no) 2005-11-25
AU2004217919A1 (en) 2004-09-16
US20070072811A1 (en) 2007-03-29
NO20054535D0 (no) 2005-10-03
CA2517970A1 (en) 2004-09-16
JP2006523229A (ja) 2006-10-12

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]