BRPI0408474A - combinação de amidas de ácidos fenilcarboxìlico com bloqueadores de canal de ikr e uso dos mesmos para tratamento de arritmias do átrio - Google Patents
combinação de amidas de ácidos fenilcarboxìlico com bloqueadores de canal de ikr e uso dos mesmos para tratamento de arritmias do átrioInfo
- Publication number
- BRPI0408474A BRPI0408474A BRPI0408474-8A BRPI0408474A BRPI0408474A BR PI0408474 A BRPI0408474 A BR PI0408474A BR PI0408474 A BRPI0408474 A BR PI0408474A BR PI0408474 A BRPI0408474 A BR PI0408474A
- Authority
- BR
- Brazil
- Prior art keywords
- channel blockers
- combination
- treatment
- acid amides
- phenylcarboxylic acid
- Prior art date
Links
- 206010003130 Arrhythmia supraventricular Diseases 0.000 title abstract 3
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical class NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 title abstract 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 2
- 229920002472 Starch Polymers 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 235000019698 starch Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Quinoline Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10312061A DE10312061A1 (de) | 2003-03-18 | 2003-03-18 | Kombination von Phenylcarbonsäureamiden mit Blockern des IK-Kanals und deren Verwendung zur Behandlung von Vorhofarrhythmien |
| PCT/EP2004/002246 WO2004082716A1 (de) | 2003-03-18 | 2004-03-05 | KOMBINATION VON PHENYLCARBONSÄUREAMIDEN MIT BLOCKERN DES IKr-KANALS UND DEREN VERWENDUNG ZUR BEHANDLUNG VON VORHOFARRHYTHMIEN |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0408474A true BRPI0408474A (pt) | 2006-04-04 |
Family
ID=32920926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0408474-8A BRPI0408474A (pt) | 2003-03-18 | 2004-03-05 | combinação de amidas de ácidos fenilcarboxìlico com bloqueadores de canal de ikr e uso dos mesmos para tratamento de arritmias do átrio |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1605976B1 (de) |
| JP (1) | JP4658919B2 (de) |
| AR (1) | AR043623A1 (de) |
| AT (1) | ATE458481T1 (de) |
| AU (1) | AU2004222642A1 (de) |
| BR (1) | BRPI0408474A (de) |
| CA (1) | CA2519002A1 (de) |
| DE (2) | DE10312061A1 (de) |
| MX (1) | MXPA05009759A (de) |
| PE (1) | PE20041060A1 (de) |
| TW (1) | TW200503675A (de) |
| WO (1) | WO2004082716A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7569589B2 (en) | 2004-07-29 | 2009-08-04 | Merck & Co., Inc. | Potassium channel inhibitors |
| KR101605061B1 (ko) | 2009-05-29 | 2016-03-21 | 라퀄리아 파마 인코포레이티드 | 칼슘 또는 나트륨 채널 차단제로서의 아릴 치환된 카복사미드 유도체 |
| US11610660B1 (en) | 2021-08-20 | 2023-03-21 | AltaThera Pharmaceuticals LLC | Antiarrhythmic drug dosing methods, medical devices, and systems |
| US11344518B2 (en) | 2018-08-14 | 2022-05-31 | AltaThera Pharmaceuticals LLC | Method of converting atrial fibrillation to normal sinus rhythm and loading oral sotalol in a shortened time frame |
| US12396970B2 (en) | 2021-08-20 | 2025-08-26 | AltaThera Pharmaceuticals LLC | Anti-arrhythmic compositions and methods |
| US10512620B1 (en) | 2018-08-14 | 2019-12-24 | AltaThera Pharmaceuticals, LLC | Method of initiating and escalating sotalol hydrochloride dosing |
| US11696902B2 (en) | 2018-08-14 | 2023-07-11 | AltaThera Pharmaceuticals, LLC | Method of initiating and escalating sotalol hydrochloride dosing |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19947457A1 (de) * | 1999-10-02 | 2001-04-05 | Aventis Pharma Gmbh | 2'-Substituierte 1,1'-Biphenyl-2-carbonamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie enthaltende pharmazeutische Zubereitungen |
| DE10121003A1 (de) * | 2001-04-28 | 2002-12-19 | Aventis Pharma Gmbh | Anthranilsäureamide, Verfahren zur Herstellung, ihrer Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| DE10121002A1 (de) * | 2001-04-28 | 2002-11-14 | Aventis Pharma Gmbh | Verwendung von Anthranilsäureamiden als Medikament zur Behandlung von Arrhythmien sowie sie enthaltende pharmazeutische Zubereitungen |
| DE10128331A1 (de) * | 2001-06-12 | 2002-12-19 | Aventis Pharma Gmbh | Anthranilsäureamide mit Heteroarylsulfonyl-Seitenkette, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen |
-
2003
- 2003-03-18 DE DE10312061A patent/DE10312061A1/de not_active Withdrawn
-
2004
- 2004-03-05 WO PCT/EP2004/002246 patent/WO2004082716A1/de not_active Ceased
- 2004-03-05 EP EP04717614A patent/EP1605976B1/de not_active Expired - Lifetime
- 2004-03-05 PE PE2004000244A patent/PE20041060A1/es not_active Application Discontinuation
- 2004-03-05 MX MXPA05009759A patent/MXPA05009759A/es not_active Application Discontinuation
- 2004-03-05 DE DE502004010806T patent/DE502004010806D1/de not_active Expired - Lifetime
- 2004-03-05 BR BRPI0408474-8A patent/BRPI0408474A/pt not_active IP Right Cessation
- 2004-03-05 JP JP2006504552A patent/JP4658919B2/ja not_active Expired - Fee Related
- 2004-03-05 AT AT04717614T patent/ATE458481T1/de not_active IP Right Cessation
- 2004-03-05 CA CA002519002A patent/CA2519002A1/en not_active Abandoned
- 2004-03-05 AU AU2004222642A patent/AU2004222642A1/en not_active Abandoned
- 2004-03-16 TW TW093106898A patent/TW200503675A/zh unknown
- 2004-03-16 AR ARP040100867A patent/AR043623A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR043623A1 (es) | 2005-08-03 |
| MXPA05009759A (es) | 2005-10-26 |
| ATE458481T1 (de) | 2010-03-15 |
| DE502004010806D1 (de) | 2010-04-08 |
| JP2006520342A (ja) | 2006-09-07 |
| TW200503675A (en) | 2005-02-01 |
| PE20041060A1 (es) | 2005-02-23 |
| JP4658919B2 (ja) | 2011-03-23 |
| CA2519002A1 (en) | 2004-09-30 |
| DE10312061A1 (de) | 2004-09-30 |
| AU2004222642A1 (en) | 2004-09-30 |
| WO2004082716A1 (de) | 2004-09-30 |
| EP1605976A1 (de) | 2005-12-21 |
| EP1605976B1 (de) | 2010-02-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A, 6A, 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012. |