BRPI0408959A - combinação sinergìstica de modulador e imunossupressor de células t de macrolìdeo e um retinóide - Google Patents
combinação sinergìstica de modulador e imunossupressor de células t de macrolìdeo e um retinóideInfo
- Publication number
- BRPI0408959A BRPI0408959A BRPI0408959-6A BRPI0408959A BRPI0408959A BR PI0408959 A BRPI0408959 A BR PI0408959A BR PI0408959 A BRPI0408959 A BR PI0408959A BR PI0408959 A BRPI0408959 A BR PI0408959A
- Authority
- BR
- Brazil
- Prior art keywords
- retinoid
- macrolide
- immunosuppressant
- combination
- synergistically
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"COMBINAçãO SINERGìSTICA DE MODULADOR E IMUNOSSUPRESSOR DE CéLULAS T DE MACROLìDEO E UM RETINóIDE". A presente invenção refere-se a combinações aditivas ou sinergísticas de um imunomodulador ou imunossupressor de células T de macrolídeo, tal como 33-epicloro-33-desoxiascomicina, e um retinóide, tais como etretinato, isotretinoína ou tazaroteno, opcionalmente com um outro agente farmaceuticamente ativo, especialmente um antibacteriano, que são proporcionadas, as quais são usadas, em particular, no tratamento de doenças dermatológicas tais como eczema, dermatite atópica, acne, psoríase, envelhecimento da pele, danos pelo sol, eritema pós-descamação e marcas de rugas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0307864.9A GB0307864D0 (en) | 2003-04-04 | 2003-04-04 | Pharmaceutical composition |
| PCT/EP2004/003511 WO2004087118A2 (en) | 2003-04-04 | 2004-04-02 | Synergistic combinations of macrolide t-cell modulator or inmunosuppressant and a retinoid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0408959A true BRPI0408959A (pt) | 2006-04-04 |
Family
ID=9956227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0408959-6A BRPI0408959A (pt) | 2003-04-04 | 2004-04-02 | combinação sinergìstica de modulador e imunossupressor de células t de macrolìdeo e um retinóide |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20060100187A1 (pt) |
| EP (1) | EP1638543A2 (pt) |
| JP (1) | JP2006522057A (pt) |
| CN (1) | CN100475199C (pt) |
| AU (1) | AU2004226819B2 (pt) |
| BR (1) | BRPI0408959A (pt) |
| CA (1) | CA2518245A1 (pt) |
| GB (1) | GB0307864D0 (pt) |
| IS (1) | IS8112A (pt) |
| MX (1) | MXPA05010701A (pt) |
| NO (1) | NO20055179L (pt) |
| RS (1) | RS20050660A (pt) |
| WO (1) | WO2004087118A2 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060234250A1 (en) * | 2005-04-15 | 2006-10-19 | Powers Ralph W Iii | Methods of screening and compositions for life span modulators |
| EP2432453A2 (en) * | 2009-05-20 | 2012-03-28 | Ranbaxy Laboratories Limited | Topical retinoid solutions |
| US10022348B2 (en) | 2009-05-20 | 2018-07-17 | Sun Pharmaceutical Industries Limited | Topical solution of isotretinoin |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0003932D0 (en) * | 2000-02-18 | 2000-04-12 | Novartis Ag | Pharmaceutical compositions |
| PL368556A1 (en) * | 2001-02-01 | 2005-04-04 | Biogen, Inc. | Methods for treating or preventing skin disorders using cd2-binding agents |
| BR0209474A (pt) * | 2001-05-09 | 2006-02-07 | Novartis Ag | Métodos para imunomodulação seletiva |
| US20030021816A1 (en) * | 2001-06-06 | 2003-01-30 | Sewon Kang | Compositions and methods for use against acne-induced inflammation and dermal matrix-degrading enzymes |
| US7887842B2 (en) * | 2003-02-07 | 2011-02-15 | Teikoku Pharma Usa, Inc. | Methods of administering a dermatological agent to a subject |
| TW200509958A (en) * | 2003-02-14 | 2005-03-16 | Combinatorx Inc | Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines |
| GB0307862D0 (en) * | 2003-04-04 | 2003-05-14 | Novartis Ag | Pharmaceutical composition |
-
2003
- 2003-04-04 GB GBGB0307864.9A patent/GB0307864D0/en not_active Ceased
-
2004
- 2004-04-02 BR BRPI0408959-6A patent/BRPI0408959A/pt not_active IP Right Cessation
- 2004-04-02 US US10/550,358 patent/US20060100187A1/en not_active Abandoned
- 2004-04-02 MX MXPA05010701A patent/MXPA05010701A/es not_active Application Discontinuation
- 2004-04-02 AU AU2004226819A patent/AU2004226819B2/en not_active Ceased
- 2004-04-02 WO PCT/EP2004/003511 patent/WO2004087118A2/en not_active Ceased
- 2004-04-02 EP EP04725373A patent/EP1638543A2/en not_active Withdrawn
- 2004-04-02 CN CNB2004800080941A patent/CN100475199C/zh not_active Expired - Fee Related
- 2004-04-02 JP JP2006504964A patent/JP2006522057A/ja active Pending
- 2004-04-02 CA CA002518245A patent/CA2518245A1/en not_active Abandoned
- 2004-04-02 RS YUP-2005/0660A patent/RS20050660A/sr unknown
-
2005
- 2005-11-01 IS IS8112A patent/IS8112A/is unknown
- 2005-11-03 NO NO20055179A patent/NO20055179L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004087118A3 (en) | 2005-04-07 |
| RS20050660A (sr) | 2007-11-15 |
| CN100475199C (zh) | 2009-04-08 |
| AU2004226819A1 (en) | 2004-10-14 |
| CA2518245A1 (en) | 2004-10-14 |
| AU2004226819B2 (en) | 2008-02-28 |
| CN1764444A (zh) | 2006-04-26 |
| WO2004087118A2 (en) | 2004-10-14 |
| IS8112A (is) | 2005-11-01 |
| GB0307864D0 (en) | 2003-05-14 |
| JP2006522057A (ja) | 2006-09-28 |
| NO20055179L (no) | 2006-01-04 |
| MXPA05010701A (es) | 2005-12-12 |
| EP1638543A2 (en) | 2006-03-29 |
| NO20055179D0 (no) | 2005-11-03 |
| US20060100187A1 (en) | 2006-05-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUI DADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011. |