BRPI0409169A - compostos orgánicos - Google Patents
compostos orgánicosInfo
- Publication number
- BRPI0409169A BRPI0409169A BRPI0409169-8A BRPI0409169A BRPI0409169A BR PI0409169 A BRPI0409169 A BR PI0409169A BR PI0409169 A BRPI0409169 A BR PI0409169A BR PI0409169 A BRPI0409169 A BR PI0409169A
- Authority
- BR
- Brazil
- Prior art keywords
- organic compounds
- ceramide
- desociascomycin
- epichloro
- xerosis
- Prior art date
Links
- 150000002894 organic compounds Chemical class 0.000 title abstract 2
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 abstract 1
- 206010012438 Dermatitis atopic Diseases 0.000 abstract 1
- 206010012442 Dermatitis contact Diseases 0.000 abstract 1
- 206010013786 Dry skin Diseases 0.000 abstract 1
- 206010014190 Eczema asteatotic Diseases 0.000 abstract 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 abstract 1
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 abstract 1
- ATGQXSBKTQANOH-UWVGARPKSA-N N-oleoylphytosphingosine Chemical compound CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@H](CO)NC(=O)CCCCCCC\C=C/CCCCCCCC ATGQXSBKTQANOH-UWVGARPKSA-N 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 206010048222 Xerosis Diseases 0.000 abstract 1
- 201000008937 atopic dermatitis Diseases 0.000 abstract 1
- 229940106189 ceramide Drugs 0.000 abstract 1
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 abstract 1
- -1 ceramide 3 Chemical compound 0.000 abstract 1
- 229940044176 ceramide 3 Drugs 0.000 abstract 1
- 208000010247 contact dermatitis Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000037336 dry skin Effects 0.000 abstract 1
- 239000002955 immunomodulating agent Substances 0.000 abstract 1
- 229940121354 immunomodulator Drugs 0.000 abstract 1
- 230000002584 immunomodulator Effects 0.000 abstract 1
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 1
- 230000001861 immunosuppressant effect Effects 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 abstract 1
- 235000020778 linoleic acid Nutrition 0.000 abstract 1
- 239000003120 macrolide antibiotic agent Substances 0.000 abstract 1
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 abstract 1
- 239000011885 synergistic combination Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"COMPOSTOS ORGáNICOS". A presente invenção refere-se a uma combinação sinergística de um imunomodulador ou imunossupressor da célula T macrolídeo tal como 33-epicloro-33-desociascomicina e uma ceramida tal como ceramida 3, LPC-9S ou ácido linoléico é fornecido, que são úteis em particular no tratamento de doenças dermatológicas ou da mucosa tais como dermatite atópica ou de contato ou pele seca, eczema asteatótica ou xerose.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0307867.2A GB0307867D0 (en) | 2003-04-04 | 2003-04-04 | Pharmaceutical composition |
| PCT/EP2004/003514 WO2004087202A2 (en) | 2003-04-04 | 2004-04-02 | Pharmaceutical composition comprising a macrolide immunomodulator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0409169A true BRPI0409169A (pt) | 2006-04-11 |
Family
ID=9956230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0409169-8A BRPI0409169A (pt) | 2003-04-04 | 2004-04-02 | compostos orgánicos |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20070021377A1 (pt) |
| EP (1) | EP1638558A2 (pt) |
| JP (1) | JP2006522060A (pt) |
| CN (1) | CN1764455A (pt) |
| BR (1) | BRPI0409169A (pt) |
| CA (1) | CA2519958A1 (pt) |
| GB (1) | GB0307867D0 (pt) |
| IS (1) | IS8103A (pt) |
| MX (1) | MXPA05010704A (pt) |
| NO (1) | NO20055170L (pt) |
| RS (1) | RS20050723A (pt) |
| WO (1) | WO2004087202A2 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2885491B1 (fr) * | 2005-05-16 | 2020-03-06 | Nutricos Technologies | Traitement de la secheresse keratinique par des glycerides |
| DE102007052380A1 (de) * | 2007-10-31 | 2009-05-07 | Bitop Ag | Osmolythaltige Zubereitungen zur Anwendung bei trockenen Schleimhäuten |
| CN120754079A (zh) * | 2024-07-30 | 2025-10-10 | 中山大学 | 亚油酸在制备提高革兰氏阳性菌对抗生素敏感性药物中的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9221220D0 (en) * | 1992-10-09 | 1992-11-25 | Sandoz Ag | Organic componds |
| FR2710527B1 (fr) * | 1993-09-30 | 1995-12-08 | Roussel Uclaf | Nouvelles compositions cosmétiques et dermatologiques associant céramides et acide linoléique, leur préparation. |
| JPH08133979A (ja) * | 1994-09-16 | 1996-05-28 | Sando Yakuhin Kk | 局所適用薬剤組成物 |
| NZ331824A (en) * | 1994-10-26 | 2000-01-28 | Novartis Ag | use of an unsaturated fatty alcohol to stabilise a macrolide in a pharmaceutical composition |
| DE19544507B4 (de) * | 1995-11-29 | 2007-11-15 | Novartis Ag | Cyclosporin enthaltende Präparate |
| GB9601120D0 (en) * | 1996-01-19 | 1996-03-20 | Sandoz Ltd | Organic compounds |
| PT2198858E (pt) * | 1998-03-26 | 2011-09-01 | Astellas Pharma Inc | Composição farmacêutica de libertação constante que contém um macrólido como o tacrolimus |
| GB0003932D0 (en) * | 2000-02-18 | 2000-04-12 | Novartis Ag | Pharmaceutical compositions |
| GB0125443D0 (en) * | 2001-10-23 | 2001-12-12 | Novartis Ag | Organic Compounds |
| GB0200429D0 (en) * | 2002-01-09 | 2002-02-27 | Novartis Ag | Organic compounds |
-
2003
- 2003-04-04 GB GBGB0307867.2A patent/GB0307867D0/en not_active Ceased
-
2004
- 2004-04-02 JP JP2006504967A patent/JP2006522060A/ja active Pending
- 2004-04-02 RS YUP-2005/0723A patent/RS20050723A/sr unknown
- 2004-04-02 US US10/550,356 patent/US20070021377A1/en not_active Abandoned
- 2004-04-02 CA CA002519958A patent/CA2519958A1/en not_active Abandoned
- 2004-04-02 MX MXPA05010704A patent/MXPA05010704A/es unknown
- 2004-04-02 BR BRPI0409169-8A patent/BRPI0409169A/pt not_active IP Right Cessation
- 2004-04-02 CN CNA2004800080903A patent/CN1764455A/zh active Pending
- 2004-04-02 WO PCT/EP2004/003514 patent/WO2004087202A2/en not_active Ceased
- 2004-04-02 EP EP04725363A patent/EP1638558A2/en not_active Withdrawn
-
2005
- 2005-10-31 IS IS8103A patent/IS8103A/is unknown
- 2005-11-03 NO NO20055170A patent/NO20055170L/no not_active Application Discontinuation
-
2007
- 2007-10-10 US US11/973,849 patent/US20080132534A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1638558A2 (en) | 2006-03-29 |
| CN1764455A (zh) | 2006-04-26 |
| AU2004226822A1 (en) | 2004-10-14 |
| US20070021377A1 (en) | 2007-01-25 |
| IS8103A (is) | 2005-10-31 |
| GB0307867D0 (en) | 2003-05-14 |
| WO2004087202A3 (en) | 2005-02-03 |
| MXPA05010704A (es) | 2005-12-12 |
| NO20055170L (no) | 2006-01-04 |
| CA2519958A1 (en) | 2004-10-14 |
| RS20050723A (sr) | 2007-11-15 |
| JP2006522060A (ja) | 2006-09-28 |
| US20080132534A1 (en) | 2008-06-05 |
| NO20055170D0 (no) | 2005-11-03 |
| WO2004087202A2 (en) | 2004-10-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UA106367C2 (uk) | Похідні азадиспіро[3.0.4.1]декану та їх застосування | |
| BRPI0919020A2 (pt) | Uso de células de linhagem monocitária enriquecidas para tratar isquemia e para tratar angina pectoris | |
| MY147247A (en) | Organic compounds and their uses | |
| BR0308289A (pt) | Antibióticos do tipo florfenicol | |
| MX2010004074A (es) | Combinacion 059. | |
| UA99839C2 (ru) | Бензодиазепиноновые соединения, применяемые при лечении кожных состояний | |
| PA8719401A1 (es) | Compuestos de tetrahidropiridotienopirimidina y metodos para su empleo | |
| TW200744661A (en) | Topical cosmetic formulations for regulating and improving the moisture content of the skin | |
| WO2010097788A3 (en) | Visfatin therapeutic agents for the treatment of acne and other conditions | |
| MXPA05010708A (es) | Composicion farmaceutica que comprende un inmunosupresor para utilizarse en el tratamiento de enfermedades de la piel. | |
| ATE414526T1 (de) | Zubereitungen zur behandlung von arthritischen erscheinungen | |
| WO2010074936A3 (en) | Enzastaurin for the treatment of cancer | |
| WO2008051523A3 (en) | Carbazole derivatives useful as medicaments in cancer therapy | |
| BR0108403A (pt) | Composições farmacéuticas | |
| MX2010009488A (es) | Métodos para modular la actividad del receptor de mc5, y tratamiento de las afecciones relacionadas con este receptor. | |
| EA200700044A1 (ru) | Композиция для местного применения | |
| WO2006108681A3 (en) | Substances and pharmaceutical compositions for the inhibition of glyoxalases and their use against bacteria | |
| MX2010005915A (es) | Derivados de fenil-oxetanilo. | |
| MXPA05010704A (es) | Composiciones farmaceuticas que comprenden un inmunomodulador de macrolido. | |
| MX2007005645A (es) | Composicion farmaceutica que comprende un inmunomodulador de celulas-t de macrolidos y un agente contra el foto-envejecimiento. | |
| WO2008073614A3 (en) | Composition and method for enhancing skin cell growth, proliferation and repair | |
| BR0316973A (pt) | Uso de ácido docosahexanóico como substância ativa para o tratamento de lipodistrofia | |
| WO2008078050A3 (fr) | Utilisation d'au moins un acide gras mono-insature pour le traitement des peaux, muqueuses ou semi-muqueuses et cuirs chevelus fragiles | |
| BR0108096A (pt) | Método para manter ou melhorar a sìntese de mucinas | |
| BRPI0409148A (pt) | combinação de um imunomodulador de células-t de macrolìdeo e um calciferol para o tratamento de doenças de pele ou de doença inflamatória no intestino |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A, 6A, 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012. |