BRPI0409217A - derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona - Google Patents

derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona

Info

Publication number
BRPI0409217A
BRPI0409217A BRPI0409217-1A BRPI0409217A BRPI0409217A BR PI0409217 A BRPI0409217 A BR PI0409217A BR PI0409217 A BRPI0409217 A BR PI0409217A BR PI0409217 A BRPI0409217 A BR PI0409217A
Authority
BR
Brazil
Prior art keywords
derivatives
bicycloexylphenyloxazolidinone
analogues
methods
antimicrobial derivatives
Prior art date
Application number
BRPI0409217-1A
Other languages
English (en)
Inventor
Adam Robert Renslo
Mikhail Fedor Gordeev
Dinesh Vinoobhai Patel
Hongwu Gao
Vara Prassad Venkata N Josyula
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of BRPI0409217A publication Critical patent/BRPI0409217A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"DERIVADOS E ANáLOGOS ANTIMICROBIANOS DA ¢3.1.0! BICICLOEXILFENILOXAZOLIDINONA". A presente invenção proporciona alguns derivados ¢3.1.0! bicíclicos de oxazolidinona de Fórmula I ou seus sais ou promedicamentos farmaceuticamente aceitáveis que são agentes antibacterianos, composições farmacêuticas que os contêm, métodos para a sua utilização e métodos para preparar estes compostos.
BRPI0409217-1A 2003-04-09 2004-03-30 derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona BRPI0409217A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46113403P 2003-04-09 2003-04-09
PCT/IB2004/001135 WO2004089943A1 (en) 2003-04-09 2004-03-30 Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues

Publications (1)

Publication Number Publication Date
BRPI0409217A true BRPI0409217A (pt) 2006-03-28

Family

ID=33159819

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409217-1A BRPI0409217A (pt) 2003-04-09 2004-03-30 derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona

Country Status (7)

Country Link
US (2) US7279494B2 (pt)
EP (1) EP1615916A1 (pt)
JP (1) JP2006522791A (pt)
BR (1) BRPI0409217A (pt)
CA (1) CA2521685A1 (pt)
MX (1) MXPA05010783A (pt)
WO (1) WO2004089943A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5043428B2 (ja) 2003-06-03 2012-10-10 リブ−エックス ファーマシューティカルズ，インコーポレイテッド ビアリール複素環式化合物ならびにその製造および使用方法
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
WO2005005399A1 (en) * 2003-07-02 2005-01-20 Merck & Co., Inc. Oxazolidinone antibiotics and derivatives thereof
DE602004027811D1 (de) * 2003-07-02 2010-08-05 Kyorin Seiyaku Kk Cyclopropylgruppensubstituierte oxazolidinonantibiotika und derivate davon
AR046782A1 (es) 2003-12-17 2005-12-21 Rib X Pharmaceuticals Inc Compuestos heterociclicos de biarilo halogenados, composiciones farmaceuticas que los contienen, metodos para su elaboracion y su uso como medicamentos.
DE602006019870D1 (de) 2005-06-08 2011-03-10 Rib X Pharmaceuticals Inc Verfahren zur synthese von triazolen
EP2367820B1 (en) 2008-11-20 2016-09-21 Panacea Biotec Limited Novel antimicrobial agents
BR112012000657A2 (pt) 2009-06-26 2016-11-16 Panacea Biotec Ltd novos azabicilohexanos
JP2013542929A (ja) 2010-09-28 2013-11-28 パナセア バイオテック リミテッド 新規ビシクロ環化合物
WO2012059823A1 (en) * 2010-11-03 2012-05-10 Wockhardt Limited Process for the preparation of phosphoric acid mono- (l-{4- [(s) -5- (acetylaminomethyl) - 2 - oxo - oxazolidin- 3 - yl] - 2, 6 - difluorophenyl} - 4 -methoxymethylpiperidin- 4 - yl) ester
JP7743829B2 (ja) * 2021-11-05 2025-09-25 小野薬品工業株式会社 Ｋｄｍ５阻害作用を有する化合物を含有する医薬組成物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) * 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4837028A (en) * 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
CN1138765C (zh) 1997-05-30 2004-02-18 法玛西雅厄普约翰美国公司 带有硫代羰基功能基的噁唑烷酮抗菌剂
KR20010015910A (ko) * 1998-01-23 2001-02-26 로렌스 티. 마이젠헬더 옥사졸리디논 조합 라이브러리, 조성물 및 제조 방법
TR200003595T2 (tr) 1998-06-05 2001-07-23 Astrazeneca Ab Kimyasal bileşikler
GB9821938D0 (en) 1998-10-09 1998-12-02 Zeneca Ltd Chemical compounds
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
HUP0203869A2 (hu) * 1999-12-21 2003-07-28 Pharmacia & Upjohn Co. Szulfoximin funkcionalitással rendelkező oxazolidinok és alkalmazásuk mikrobaellenes szerként, a vegyületeket tartalmazó gyógyszerkészítmények
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
BR0112826A (pt) 2000-07-17 2003-06-24 Ranbaxy Lab Ltd Derivados da oxazolidinona como antimicrobianos
DE60118241T2 (de) * 2000-10-17 2006-12-28 Pharmacia & Upjohn Co. Llc, Kalamazoo Verfahren zur herstellung von oxazolidinonverbindungen
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados

Also Published As

Publication number Publication date
US20080090884A1 (en) 2008-04-17
MXPA05010783A (es) 2005-12-12
JP2006522791A (ja) 2006-10-05
EP1615916A1 (en) 2006-01-18
WO2004089943A1 (en) 2004-10-21
CA2521685A1 (en) 2004-10-21
US7279494B2 (en) 2007-10-09
US20050192325A1 (en) 2005-09-01
WO2004089943A8 (en) 2005-09-29

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.