BRPI0409217A - derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona - Google Patents

derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona

Info

Publication number
BRPI0409217A
BRPI0409217A BRPI0409217-1A BRPI0409217A BRPI0409217A BR PI0409217 A BRPI0409217 A BR PI0409217A BR PI0409217 A BRPI0409217 A BR PI0409217A BR PI0409217 A BRPI0409217 A BR PI0409217A
Authority
BR
Brazil
Prior art keywords
derivatives
bicycloexylphenyloxazolidinone
analogues
methods
antimicrobial derivatives
Prior art date
Application number
BRPI0409217-1A
Other languages
English (en)
Inventor
Adam Robert Renslo
Mikhail Fedor Gordeev
Dinesh Vinoobhai Patel
Hongwu Gao
Vara Prassad Venkata N Josyula
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of BRPI0409217A publication Critical patent/BRPI0409217A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"DERIVADOS E ANáLOGOS ANTIMICROBIANOS DA ¢3.1.0! BICICLOEXILFENILOXAZOLIDINONA". A presente invenção proporciona alguns derivados ¢3.1.0! bicíclicos de oxazolidinona de Fórmula I ou seus sais ou promedicamentos farmaceuticamente aceitáveis que são agentes antibacterianos, composições farmacêuticas que os contêm, métodos para a sua utilização e métodos para preparar estes compostos.
BRPI0409217-1A 2003-04-09 2004-03-30 derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona BRPI0409217A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46113403P 2003-04-09 2003-04-09
PCT/IB2004/001135 WO2004089943A1 (en) 2003-04-09 2004-03-30 Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues

Publications (1)

Publication Number Publication Date
BRPI0409217A true BRPI0409217A (pt) 2006-03-28

Family

ID=33159819

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409217-1A BRPI0409217A (pt) 2003-04-09 2004-03-30 derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona

Country Status (7)

Country Link
US (2) US7279494B2 (pt)
EP (1) EP1615916A1 (pt)
JP (1) JP2006522791A (pt)
BR (1) BRPI0409217A (pt)
CA (1) CA2521685A1 (pt)
MX (1) MXPA05010783A (pt)
WO (1) WO2004089943A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
EP1656370B1 (en) 2003-06-03 2012-08-15 Rib-X Pharmaceuticals, Inc. Biaryl heterocyclic compounds and methods of making and using the same
CA2529292A1 (en) * 2003-07-02 2005-01-20 Merck & Co., Inc. Oxazolidinone antibiotics and derivatives thereof
ATE471937T1 (de) 2003-07-02 2010-07-15 Merck Sharp & Dohme Cyclopropylgruppensubstituierte oxazolidinonantibiotika und derivate davon
AR046782A1 (es) 2003-12-17 2005-12-21 Rib X Pharmaceuticals Inc Compuestos heterociclicos de biarilo halogenados, composiciones farmaceuticas que los contienen, metodos para su elaboracion y su uso como medicamentos.
JP5534497B2 (ja) 2005-06-08 2014-07-02 メリンタ セラピューティクス，インコーポレイテッド トリアゾール類の合成方法
CN102224151A (zh) 2008-11-20 2011-10-19 万能药生物有限公司 新的抗微生物剂
KR20120106697A (ko) 2009-06-26 2012-09-26 파나세아 바이오테크 리미티드 신규 아자비시클로헥산
BR112013007566A2 (pt) 2010-09-28 2016-08-02 Panacea Biotec Ltd novos compostos bicíclicos
EP2635589A1 (en) * 2010-11-03 2013-09-11 Wockhardt Limited Process for the preparation of phosphoric acid mono- (l-{4- [(s) -5- (acetylaminomethyl) - 2 - oxo - oxazolidin- 3 - yl]- 2, 6 - difluorophenyl} - 4 -methoxymethylpiperidin- 4 - yl) ester
JP7743829B2 (ja) * 2021-11-05 2025-09-25 小野薬品工業株式会社 Ｋｄｍ５阻害作用を有する化合物を含有する医薬組成物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) * 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4837028A (en) * 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
SK156499A3 (en) 1997-05-30 2000-06-12 Upjohn Co Oxazolidinone antibacterial agents having a thiocarbonyl functionality
BR9907183A (pt) * 1998-01-23 2003-06-10 Versicor Inc Colet neas combinatórias de oxazolidinona, composições e processos de preparação
WO1999064417A2 (en) 1998-06-05 1999-12-16 Astrazeneca Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
GB9821938D0 (en) 1998-10-09 1998-12-02 Zeneca Ltd Chemical compounds
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
SK7572002A3 (en) * 1999-12-21 2002-12-03 Upjohn Co Oxazolidinones having a sulfoximine functionality and their use as antimicrobial agents
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
HUP0302918A2 (hu) 2000-07-17 2003-12-29 Ranbaxy Laboratories Limited Mikrobaellenes oxazolidinonszármazékok és a vegyületeket tartalmazó gyógyászati készítmények és eljárás a vegyületek előállítására
ES2256318T3 (es) * 2000-10-17 2006-07-16 PHARMACIA & UPJOHN COMPANY LLC Metodos de produccion de compuestos de oxazolidinona.
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados

Also Published As

Publication number Publication date
US20080090884A1 (en) 2008-04-17
WO2004089943A8 (en) 2005-09-29
US7279494B2 (en) 2007-10-09
CA2521685A1 (en) 2004-10-21
EP1615916A1 (en) 2006-01-18
WO2004089943A1 (en) 2004-10-21
US20050192325A1 (en) 2005-09-01
MXPA05010783A (es) 2005-12-12
JP2006522791A (ja) 2006-10-05

Similar Documents

Publication Publication Date Title
BR0208678A (pt) Composto, composição farmacêutica, uso de um composto
BRPI0412291A (pt) antagonistas duplos de nka/nk3 para o tratamento de esquizofrenia
BRPI0519567A2 (pt) heterociclos tricÍclicos, sua fabricaÇço e uso como agentes farmacÊuticos
BRPI0407618A (pt) derivados de tiazole amino substituidos com cicloalquilo contendo n e composições farmacêuticas para inibição da proliferação celular e métodos para a sua utilização
BRPI0607796A2 (pt) composto ou um sal farmaceuticamente aceitável do mesmo, processo para preparação e uso do mesmo, e, composição farmacêutica
BR0210028A (pt) Agentes antibacterianos
BR9911482A (pt) Composto, composição farmacêutica, uso do composto, e, processos para o tratamento ou profilaxia de doenças inflamatórias, e para a preparação de um composto
BR0109235A (pt) Derivados do ácido carboxìlico como antagonistas ip
BRPI0809977A8 (pt) Uso de um composto, compostos e composição farmacêutica que o contém
BR0214243A (pt) Derivado de sulfonamida processo para a preparação de um derivado de sulfonamida e seus sais fisiologicamente aceitáveis, composição farmacêutica e uso de um derivado de sulfonamida
SV1999000194A (es) Preparado farmaceuticio de moxifloxacina ref. lea 33327-sv
BRPI0413469A (pt) derivados de piperazina para o tratamento de infecções por hiv
BRPI0407097A (pt) Antagonista do casr
HN2000000115A (es) Formulacion de sal comun y moxifloxacina
BRPI0408437A (pt) derivados de p-diaminobenzeno substituìdos, composição farmacêutica, e, uso da mesma
BR0306870A (pt) Composição farmacêutica oral, e, método para preparar a mesma
BRPI0706992C1 (pt) composto de fórmula (i) e formulação farmacêutica
BR0212787A (pt) Composto ou sal farmaceuticamente aceitável do mesmo, métodos de tratamento ou prevenção de doenças e de preparação de um composto, uso de um composto ou sal, e, composição farmacêutica
BR0010938A (pt) Derivados da 13-metil eritromicina
BRPI0513672A (pt) processo aperfeiçoado para a preparação de 2h-1-benzopiran-2metanol, (alfa). (alfa)' [iminobis (metileno)] bis [6-fluoro-3, 4-dihidro, [2r* [r* [r* (s*)]]]], composição farmacêutica, forma t1 amorfa, e processo para a preparação da forma t1 de hidrocloreto de nebivolol
BR0210285A (pt) Utilização de um composto, composto e composição farmacêutica
BR0212069A (pt) Agentes antidiabéticos orais
BR0113590A (pt) 7-oxo-piridopirimidinas
BRPI0409217A (pt) derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona
BRPI0414780A (pt) composto, uso do mesmo, composição farmacêutica, e, métodos para a terapia da dor em um animal de sangue quente, e para preparar um composto

Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.