BRPI0409516A - composição, uso de uma composição e processo de melhora da penetração de um ativo farmacêutico - Google Patents

composição, uso de uma composição e processo de melhora da penetração de um ativo farmacêutico

Info

Publication number
BRPI0409516A
BRPI0409516A BRPI0409516-2A BRPI0409516A BRPI0409516A BR PI0409516 A BRPI0409516 A BR PI0409516A BR PI0409516 A BRPI0409516 A BR PI0409516A BR PI0409516 A BRPI0409516 A BR PI0409516A
Authority
BR
Brazil
Prior art keywords
composition
pharmaceutical active
enhancing penetration
pharmaceutical
penetration
Prior art date
Application number
BRPI0409516-2A
Other languages
English (en)
Inventor
Claire Mallard
Franck Pitre
Laurent Fredon
Original Assignee
Galderma Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Res & Dev filed Critical Galderma Res & Dev
Publication of BRPI0409516A publication Critical patent/BRPI0409516A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

"COMPOSIçãO, USO DE UMA COMPOSIçãO E PROCESSO DE MELHORA DA PENETRAçãO DE UM ATIVO FARMACêUTICO". A presente invenção trata de uma composição em forma de spray que compreende um ativo farmacêutico, pelo menos um silicone volátil e uma fase oleosa não volátil em um meio fisiologicamente aceitável, de seu processo de preparação e de seu uso em cosmética e em dermatologia.
BRPI0409516-2A 2003-06-23 2004-06-18 composição, uso de uma composição e processo de melhora da penetração de um ativo farmacêutico BRPI0409516A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0307551A FR2856301B1 (fr) 2003-06-23 2003-06-23 Composition sous forme de spray comprenant un actif pharmaceutique, au moins un silicone volatile et une phase non polaire non volatile
PCT/EP2004/007203 WO2004112798A1 (fr) 2003-06-23 2004-06-18 Compositions sous forme de spray comprenant un actif pharmaceutique, au moins un silicone volatile et une phase huileuse non volatile

Publications (1)

Publication Number Publication Date
BRPI0409516A true BRPI0409516A (pt) 2006-04-18

Family

ID=33484645

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409516-2A BRPI0409516A (pt) 2003-06-23 2004-06-18 composição, uso de uma composição e processo de melhora da penetração de um ativo farmacêutico

Country Status (15)

Country Link
US (2) US20060147383A1 (pt)
EP (1) EP1641463B1 (pt)
KR (1) KR20060021326A (pt)
CN (1) CN1809363A (pt)
AR (1) AR044872A1 (pt)
AT (1) ATE424829T1 (pt)
AU (1) AU2004248926A1 (pt)
BR (1) BRPI0409516A (pt)
CA (1) CA2526642A1 (pt)
DE (1) DE602004019922D1 (pt)
ES (1) ES2322269T3 (pt)
FR (1) FR2856301B1 (pt)
MX (1) MXPA05013232A (pt)
RU (1) RU2006101698A (pt)
WO (1) WO2004112798A1 (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8337870B2 (en) 2009-12-15 2012-12-25 Young Pharmaceuticals, Inc. Low toxicity topical active agent delivery system

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2867682B1 (fr) * 2004-03-22 2009-06-05 Galderma Res & Dev Composition pharmaceutique anhydre associant un agent silicone et un principe actif solubilise.
FR2871700B1 (fr) * 2004-06-17 2006-11-17 Galderma Sa Composition sous forme de spray comprenant une association d'actifs pharmaceutiques, une phase alcoolique, et une phase huileuse
DK1771180T4 (da) * 2004-06-17 2011-04-11 Galderma Sa Sammensætning i form af en spray, der omfatter en kombination af clobetasolpropionat og calcitriol, en alkoholfase og en oliefase
FR2871697B1 (fr) * 2004-06-17 2007-06-29 Galderma Sa Composition sous forme de spray comprenant une association d'actifs pharmaceutiques, une phase alcoolique, au moins un silicone volatile et une phase huileuse non volatile
FR2871698B1 (fr) * 2004-06-17 2008-07-04 Galderma Sa Composition sous forme de spray comprenant une association d'actifs pharmaceutiques et une phase huileuse
AU2005253733A1 (en) * 2004-06-17 2005-12-29 Galderma S.A. Composition in spray form comprising a combination of a corticoid and a vitamin D derivative in an oily phase
CA2618993A1 (en) * 2005-08-13 2007-02-22 Collegium Pharmaceutical, Inc. Topical delivery with a carrier fluid
FR2893845B1 (fr) * 2005-11-30 2010-10-29 Galderma Sa Composition sous forme de spray comprenant un corticoide et une phase huileuse
US10265265B2 (en) 2007-03-15 2019-04-23 Drug Delivery Solutions Limited Topical composition
EP1970048A1 (en) * 2007-03-15 2008-09-17 Drug Delivery Solutions Limited Polyaphron topical composition with vitamin D
EP2008651A1 (en) 2007-06-26 2008-12-31 Drug Delivery Solutions Limited A bioerodible patch
AR068408A1 (es) * 2007-09-14 2009-11-18 Drugtech Corp Pulverizacion de hormonas transdermicas
AR068409A1 (es) * 2007-09-14 2009-11-18 Drugtech Corp Composiciones farmaceuticas, transdermicas sin alcohol
US20090175810A1 (en) 2008-01-03 2009-07-09 Gareth Winckle Compositions and methods for treating diseases of the nail
JP5833007B2 (ja) 2009-08-31 2015-12-16 ドクター・レディーズ・ラボラトリーズ・リミテッド ステロイドを含む局所製剤
WO2011056116A1 (en) * 2009-11-03 2011-05-12 Lipidor Ab Composition for promoting wound healing
NZ599933A (en) 2009-11-03 2014-08-29 Lipidor Ab Lipid layer forming composition for administration onto a surface of a living organism
GB0919650D0 (en) * 2009-11-10 2009-12-23 Futura Medical Developments Ltd Pharmaceutical composition
US8039494B1 (en) 2010-07-08 2011-10-18 Dow Pharmaceutical Sciences, Inc. Compositions and methods for treating diseases of the nail
HRP20191711T1 (hr) 2011-03-14 2019-12-13 Drug Delivery Solutions Ltd Oftalmološki pripravak
ITMI20121205A1 (it) 2012-07-11 2014-01-12 Glycores 2000 Srl Composizione con attivita' antinfiammatoria ed analgesica da somministrare per uso esterno mediante vaporizzazione
RU2715103C2 (ru) * 2013-05-03 2020-02-27 Липидор Аб Местная композиция и носитель для введения фармацевтически или косметически активных ингредиентов
AU2014329421B2 (en) 2013-10-03 2018-08-02 Dow Pharmaceutical Sciences, Inc. Stabilized efinaconazole compositions
JP6611014B2 (ja) 2013-11-22 2019-11-27 ボシュ ヘルス アイルランド リミテッド 抗感染方法、抗感染組成物、および抗感染装置
US20160184431A1 (en) 2014-03-11 2016-06-30 Promius Pharma Llc Topical compositions comprising a corticosteroid
EP3242659A4 (en) 2015-01-09 2018-09-12 Chase Pharmaceuticals Corporation Oxybutynin transdermal therapeutic system combination
ES3055492T3 (en) 2015-09-16 2026-02-12 Dfb Soria Llc Delivery of drug nanoparticles and methods of use thereof
US20180000836A1 (en) * 2016-07-01 2018-01-04 Yousif Kattoula Topical Treatment for Psoriasis
WO2018170196A1 (en) 2017-03-15 2018-09-20 Dfb Soria, Llc Topical therapy for the treatment of skin malignancies using nanoparticles of taxanes
CN108970823B (zh) 2017-05-31 2021-08-06 北京小米移动软件有限公司 一种水微粒发生装置
CN206810524U (zh) 2017-05-31 2017-12-29 北京小米移动软件有限公司 一种水微粒发生装置
EP3765035A4 (en) 2018-03-16 2021-10-27 DFB Soria, LLC TOPICAL THERAPY FOR THE TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA (CIN) AND COLD CANCER USING TAXANE NANOPARTICLES
EP3542788A1 (en) 2018-03-19 2019-09-25 MC2 Therapeutics Limited Topical composition comprising calcipotriol and betamethasone dipropionate
WO2019224035A1 (en) 2018-05-24 2019-11-28 Almirall, S.A. Topical pharmaceutical compositions comprising a corticosteroid

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US136332A (en) 1873-02-25 Improvement in prepared lumber for joiners use
DE3225848A1 (de) * 1982-07-07 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Kortikoidhaltige zubereitung zur topischen applikation
US4678663A (en) * 1984-02-06 1987-07-07 Nuetrogena Corporation Hydroquinone composition having enhanced bio-availability and percutaneous adsorption
FI872553L (fi) * 1986-06-09 1987-12-10 American Cyanamid Co Medium foer laekemedel foer lokalt bruk.
US4889845A (en) * 1986-06-09 1989-12-26 American Cyanamid Company Vehicle for topical application of pharmaceuticals
JPH02145512A (ja) * 1988-11-26 1990-06-05 Shin Etsu Chem Co Ltd 被膜形成型外用剤
US6538039B2 (en) * 1994-04-29 2003-03-25 Laboratoire L. Lafon Pharmaceutical dosage form for transdermal administration
FR2737118B1 (fr) * 1995-07-28 1997-09-05 Oreal Composition dermatologique ou pharmaceutique, procede de preparation et utilisation
ZA966579B (en) * 1995-08-04 1998-02-02 Wakamoto Pharma Co Ltd O/W emulsion composition for eye drops.
FR2740038B1 (fr) * 1995-10-20 1998-01-02 Lafon Labor Composition pour l'administration transdermique
EP0966972B1 (en) * 1998-06-18 2003-09-24 Dow Corning France S.A. Topical composition containing silicon gum
US5993837A (en) * 1998-08-24 1999-11-30 Revlon Consumer Products Compositions for application to keratinous substrates and a method for strengthening such substrates
FR2787322B1 (fr) * 1998-12-18 2002-10-18 Galderma Res & Dev Emulsion huile-dans-eau comprenant un agent actif micronise et un systeme emulsionnant approprie
PT3146969T (pt) 1999-04-23 2018-10-18 Leo Pharma As Composição farmacêutica para aplicação dérmica para uso no tratamento da psoríase compreendendo vitamina d e um corticosteroide
DE10024413A1 (de) * 2000-05-19 2001-12-06 Mika Pharma Gmbh Pharmazeutische und/oder kosmetische Zubereitung
US6512072B1 (en) * 2000-06-12 2003-01-28 Dow Corning Corporation Fast cure film forming formulation
DE10113058A1 (de) * 2001-03-15 2002-09-19 Basf Ag Verwendung von Lichtschutzmittelkombinationen, die als wesentlichen Bestandteil 2-(4-Alkoxy-anilinomethylen)-malonsäure-dialkylester enthalten als photostabile UV-Filter in kosmetischen und pharmazeutischen Zubereitungen
AU2005253733A1 (en) 2004-06-17 2005-12-29 Galderma S.A. Composition in spray form comprising a combination of a corticoid and a vitamin D derivative in an oily phase

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8337870B2 (en) 2009-12-15 2012-12-25 Young Pharmaceuticals, Inc. Low toxicity topical active agent delivery system

Also Published As

Publication number Publication date
ATE424829T1 (de) 2009-03-15
CN1809363A (zh) 2006-07-26
RU2006101698A (ru) 2006-06-10
DE602004019922D1 (de) 2009-04-23
WO2004112798A1 (fr) 2004-12-29
CA2526642A1 (fr) 2004-12-29
EP1641463B1 (fr) 2009-03-11
AR044872A1 (es) 2005-10-05
FR2856301B1 (fr) 2007-08-03
US20060147383A1 (en) 2006-07-06
FR2856301A1 (fr) 2004-12-24
AU2004248926A1 (en) 2004-12-29
KR20060021326A (ko) 2006-03-07
US20100216757A1 (en) 2010-08-26
ES2322269T3 (es) 2009-06-18
EP1641463A1 (fr) 2006-04-05
MXPA05013232A (es) 2006-03-09

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.