BRPI0409960A - derivados de oxima de hidróxi-bifenil-carbaldeìdo e seu uso como agentes estrogênicos - Google Patents

derivados de oxima de hidróxi-bifenil-carbaldeìdo e seu uso como agentes estrogênicos

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Publication number
BRPI0409960A
BRPI0409960A BRPI0409960-5A BRPI0409960A BRPI0409960A BR PI0409960 A BRPI0409960 A BR PI0409960A BR PI0409960 A BRPI0409960 A BR PI0409960A BR PI0409960 A BRPI0409960 A BR PI0409960A
Authority
BR
Brazil
Prior art keywords
oxime derivatives
carbaldehyde oxime
estrogenic agents
hydroxy biphenyl
hydroxy
Prior art date
Application number
BRPI0409960-5A
Other languages
English (en)
Inventor
Richard Eric Mewshaw
Cijiang Yang
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of BRPI0409960A publication Critical patent/BRPI0409960A/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/48—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Abstract

"DERIVADOS DE OXIMA DE HIDRóXI-BIFENIL-CARBALDEìDO E SEU USO COMO AGENTES ESTROGêNICOS". A presente invenção refere-se a moduladores de receptores de estrogênios, que têm a estrutura da fórmula (I), onde: R¬ 1¬ a R¬ 6¬ e R¬ 8~ são como definidos no relatório descritivo; ou um seu sal farmaceuticamente aceitável.
BRPI0409960-5A 2003-05-02 2004-04-30 derivados de oxima de hidróxi-bifenil-carbaldeìdo e seu uso como agentes estrogênicos BRPI0409960A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46739403P 2003-05-02 2003-05-02
US10/835,228 US7279600B2 (en) 2003-05-02 2004-04-29 Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents
PCT/US2004/013316 WO2004099122A2 (en) 2003-05-02 2004-04-30 Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents

Publications (1)

Publication Number Publication Date
BRPI0409960A true BRPI0409960A (pt) 2006-04-25

Family

ID=33436730

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409960-5A BRPI0409960A (pt) 2003-05-02 2004-04-30 derivados de oxima de hidróxi-bifenil-carbaldeìdo e seu uso como agentes estrogênicos

Country Status (13)

Country Link
US (2) US7279600B2 (pt)
EP (1) EP1620392B1 (pt)
JP (1) JP2006525346A (pt)
AT (1) ATE365708T1 (pt)
AU (1) AU2004236213A1 (pt)
BR (1) BRPI0409960A (pt)
CA (1) CA2523712A1 (pt)
DE (1) DE602004007257T2 (pt)
DK (1) DK1620392T3 (pt)
ES (1) ES2289538T3 (pt)
MX (1) MXPA05011679A (pt)
PL (1) PL1620392T3 (pt)
WO (1) WO2004099122A2 (pt)

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US7279600B2 (en) 2007-10-09
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US20080033049A1 (en) 2008-02-07
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ATE365708T1 (de) 2007-07-15
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