BRPI0410651A - composto, composição farmacêutica, e, métodos para tratar ou prevenir cáncer, degeneração macular do tipo úmida ou artrite reumatóide, vascularização aberrante, nìveis de cobre em excesso, obesidade e doença neurodegenerativa em um paciente - Google Patents

composto, composição farmacêutica, e, métodos para tratar ou prevenir cáncer, degeneração macular do tipo úmida ou artrite reumatóide, vascularização aberrante, nìveis de cobre em excesso, obesidade e doença neurodegenerativa em um paciente

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Publication number
BRPI0410651A
BRPI0410651A BRPI0410651-2A BRPI0410651A BRPI0410651A BR PI0410651 A BRPI0410651 A BR PI0410651A BR PI0410651 A BRPI0410651 A BR PI0410651A BR PI0410651 A BRPI0410651 A BR PI0410651A
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BR
Brazil
Prior art keywords
methods
obesity
treating
macular degeneration
pharmaceutical composition
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BRPI0410651-2A
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English (en)
Inventor
Robert J Ternansky
Patricia L Gladstone
Amy L Allan
Melissa L P Price
Andrew P Mazar
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Attenuon Llc
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Publication date
Application filed by Attenuon Llc filed Critical Attenuon Llc
Publication of BRPI0410651A publication Critical patent/BRPI0410651A/pt

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    • C01G41/006—Compounds containing tungsten, with or without oxygen or hydrogen, and containing two or more other elements
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    • C07F11/00—Compounds containing elements of Groups 6 or 16 of the Periodic Table
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
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  • Organic Chemistry (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
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Abstract

"COMPOSTO, COMPOSIçãO FARMACêUTICA, E, MéTODOS PARA TRATAR OU PREVENIR CáNCER DEGENERAçãO MACULAR DO TIPO úMIDA OU ARTRITE REUMATóIDE, VASCULARIZAçãO ABERRANTE, NìVEIS DE COBRE EM EXCESSO, OBESIDADE E DOENçA NEURODEGENERATIVA EM UM PACIENTE". A atual invenção fornece novos derivados de tiotungstato, métodos de fabricar novos derivados de tiotungstato, composições farmacêuticas de novos derivados de tiotungstato, métodos de usar novos derivados de tiotungstato para tratar doenças associadas com a vascularização aberrante, distúrbios do metabolismo do cobre e obesidade e métodos de usar as composições farmacêuticas de derivados de tiotungstato para tratar doenças associadas com a vascularização aberrante, distúrbios do metabolismo do cobre, distúrbios neurodegenerativos, obesidade ou desregulagem do NF-kB.
BRPI0410651-2A 2003-05-27 2004-05-27 composto, composição farmacêutica, e, métodos para tratar ou prevenir cáncer, degeneração macular do tipo úmida ou artrite reumatóide, vascularização aberrante, nìveis de cobre em excesso, obesidade e doença neurodegenerativa em um paciente BRPI0410651A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47393703P 2003-05-27 2003-05-27
PCT/US2004/016948 WO2004110364A2 (en) 2003-05-27 2004-05-27 Thiotungstate analogues and uses thereof

Publications (1)

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BRPI0410651A true BRPI0410651A (pt) 2006-07-04

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BRPI0410651-2A BRPI0410651A (pt) 2003-05-27 2004-05-27 composto, composição farmacêutica, e, métodos para tratar ou prevenir cáncer, degeneração macular do tipo úmida ou artrite reumatóide, vascularização aberrante, nìveis de cobre em excesso, obesidade e doença neurodegenerativa em um paciente

Country Status (15)

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US (2) US7851505B2 (pt)
EP (1) EP1633310A4 (pt)
JP (1) JP2007516234A (pt)
KR (1) KR20060013561A (pt)
CN (1) CN100558409C (pt)
AU (1) AU2004247059A1 (pt)
BR (1) BRPI0410651A (pt)
CA (1) CA2527236A1 (pt)
EA (1) EA200501865A1 (pt)
IL (1) IL172195A0 (pt)
MX (1) MXPA05012722A (pt)
NO (1) NO20056116L (pt)
PL (1) PL218366B1 (pt)
WO (1) WO2004110364A2 (pt)
ZA (1) ZA200509719B (pt)

Families Citing this family (11)

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Publication number Priority date Publication date Assignee Title
EP1729784A1 (en) * 2004-02-23 2006-12-13 Attenuon, LLC Formulations of thiomolybdate or thiotungstate compounds and uses thereof
CN101237875B (zh) * 2005-07-29 2011-07-13 巴塞罗纳大学 用于治疗神经退行性障碍特别是阿尔茨海默病或精神分裂症的含钨盐（vi）的药物组合物
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US7851505B2 (en) 2010-12-14
MXPA05012722A (es) 2006-05-25
KR20060013561A (ko) 2006-02-10
EP1633310A4 (en) 2006-10-18
US20110151022A1 (en) 2011-06-23
NO20056116L (no) 2006-02-24
EP1633310A2 (en) 2006-03-15
US20060160805A1 (en) 2006-07-20
PL379262A1 (pl) 2006-08-07
CN1832761A (zh) 2006-09-13
CN100558409C (zh) 2009-11-11
WO2004110364A9 (en) 2005-04-07
EA200501865A1 (ru) 2006-08-25
ZA200509719B (en) 2007-03-28
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