BRPI0410977A - processo para a fabricação de granulado de enzima e granulados de enzima obtidos - Google Patents
processo para a fabricação de granulado de enzima e granulados de enzima obtidosInfo
- Publication number
- BRPI0410977A BRPI0410977A BRPI0410977-5A BRPI0410977A BRPI0410977A BR PI0410977 A BRPI0410977 A BR PI0410977A BR PI0410977 A BRPI0410977 A BR PI0410977A BR PI0410977 A BRPI0410977 A BR PI0410977A
- Authority
- BR
- Brazil
- Prior art keywords
- enzyme
- enzyme granulates
- injection zone
- granulates
- enzyme granules
- Prior art date
Links
- 102000004190 Enzymes Human genes 0.000 title abstract 9
- 108090000790 Enzymes Proteins 0.000 title abstract 9
- 239000008187 granular material Substances 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000002347 injection Methods 0.000 abstract 3
- 239000007924 injection Substances 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 238000001035 drying Methods 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000005484 gravity Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/98—Preparation of granular or free-flowing enzyme compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/06—Enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/22—Agglomeration or granulation with pulverisation of solid particles, e.g. in a free-falling curtain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/16—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by suspending the powder material in a gas, e.g. in fluidised beds or as a falling curtain
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Nutrition Science (AREA)
- Veterinary Medicine (AREA)
- Animal Husbandry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Enzymes And Modification Thereof (AREA)
- Fodder In General (AREA)
- Detergent Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
"PROCESSO PARA A FABRICAçãO DE GRANULADO DE ENZIMA E GRANULADOS DE ENZIMA OBTIDOS". A invenção refere-se a um processo para a fabricação de granulados de enzima, a granulados de enzima obtidos com isso e a seu emprego em formulações, por exemplo, para rações, produtos alimentícios, sabões ou detergentes elou para finalidades farmacêuticas e similares. Os granulados de enzima mostram, em particular, uma cota relativamente alta de enzima ativa, tamanhos do grão determinados, boa estabilidade de armazenagem, em particular, fator de arredondamento pequeno e/ou baixa cota de umidade residual, bem como, de preferência, outras propriedades específicas. De acordo com a invenção, a fabricação de granulados de enzima ocorre por meio de uma combinação entre as condições térmicas na zona de pulverização e as condições de temperatura na outra zona do aparelho. No processo de acordo com a invenção isso é obtido pelo fato de que a condução do gás de processamento aquecido para a secagem ocorre exclusivamente na zona de pulverização. A condução segura de partículas para dentro da zona de pulverização ocorre através da forma geométrica especial do aparelho, com utilização da força da gravidade (comp. figura). Por meio de adição de partículas inertes como material de germe para núcleos, pode ser comandado o teor absoluto de atividade de enzima dos granulados de enzima.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10326231.8A DE10326231B4 (de) | 2003-06-11 | 2003-06-11 | Verfahren zur Herstellung von Enzym-Granulaten |
| DE10357827A DE10357827A1 (de) | 2003-12-09 | 2003-12-09 | Verfahren zur Herstellung von Enzym-Granulaten und erhältliche Enzym-Granulate |
| DE102004004202A DE102004004202A1 (de) | 2004-01-27 | 2004-01-27 | Herstellungsverfahren für Enzym-Granulate und erhältliche Enzym-Granulate |
| DE102004008020A DE102004008020A1 (de) | 2004-02-19 | 2004-02-19 | Enzym-Granulats-Herstellungsverfahren |
| PCT/EP2004/005662 WO2004108911A2 (de) | 2003-06-11 | 2004-05-26 | Enzym-granulat-herstellungsverfahren und erhältliche enzym-granulate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0410977A true BRPI0410977A (pt) | 2006-07-04 |
Family
ID=33514768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0410977-5A BRPI0410977A (pt) | 2003-06-11 | 2004-05-26 | processo para a fabricação de granulado de enzima e granulados de enzima obtidos |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8231938B2 (pt) |
| EP (1) | EP1638678B1 (pt) |
| JP (1) | JP4589312B2 (pt) |
| AT (1) | ATE526077T1 (pt) |
| AU (1) | AU2004245660B2 (pt) |
| BR (1) | BRPI0410977A (pt) |
| CA (1) | CA2528637C (pt) |
| DK (1) | DK1638678T3 (pt) |
| ES (1) | ES2374191T3 (pt) |
| MX (1) | MXPA05012879A (pt) |
| PL (1) | PL1638678T3 (pt) |
| PT (1) | PT1638678E (pt) |
| WO (1) | WO2004108911A2 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004022102A1 (de) * | 2004-05-05 | 2005-11-24 | Glatt Ingenieurtechnik Gmbh | Verfahren zur Verkapselung flüchtiger, oxidationsempfindlicher Substanzen sowie von Duft- und Geschmacksstoffen in Granulatform |
| DE102004023725A1 (de) * | 2004-05-11 | 2005-12-01 | Glatt Ingenieurtechnik Gmbh | Verfahren zur Verkapselung bzw. Immobilisierung von Mikroorganismen |
| DE102005037630A1 (de) | 2005-08-09 | 2007-02-15 | Glatt Gmbh | Verfahren zur Herstellung von Teilchen aus pharmazeutischen Substanzen, Teilchen aus pharmazeutischen Substanzen sowie deren Verwendung |
| DE102005043327A1 (de) * | 2005-09-12 | 2007-03-15 | Basf Ag | Verfahren zur Herstellung von festen Enzymgranulaten für Futtermittel |
| DE102005043324A1 (de) * | 2005-09-12 | 2007-03-15 | Basf Ag | Phytasehaltiges Enzymgranulat II |
| CN102742732B (zh) * | 2006-03-10 | 2015-10-28 | 巴斯夫欧洲公司 | 固态酶配制剂及其制备方法 |
| NZ586750A (en) * | 2008-02-14 | 2012-01-12 | Danisco Us Inc | Small enzyme-containing granules |
| DE102008046772A1 (de) * | 2008-09-11 | 2010-03-18 | Glatt Ingenieurtechnik Gmbh | Verfahren und Vorrichtung zur Behandlung von feinkörnigem Material in einer Strahlschicht |
| ES2497569T3 (es) * | 2009-11-10 | 2014-09-23 | Basf Se | Preparación favorable para la salud y método de producción |
| KR101897991B1 (ko) * | 2010-09-27 | 2018-09-12 | 바스프 에스이 | 하나 이상의 착화제 염을 포함하는 과립의 제조 방법 |
| US8754026B2 (en) | 2010-09-27 | 2014-06-17 | Basf Se | Process for producing granules comprising one or more complexing agent salts |
| JP6071687B2 (ja) * | 2013-03-26 | 2017-02-01 | 月島機械株式会社 | 加圧流動炉設備 |
| CA2915538C (en) * | 2013-06-19 | 2023-07-18 | Danisco Us Inc. | Granules with small smooth cores |
| MX395605B (es) * | 2016-03-16 | 2025-03-25 | Spogen Biotech Inc | Metodos para promover la salud de las plantas usando enzimas libres y microorganismos que sobreexpresan enzimas |
| CN108070518B (zh) * | 2018-02-11 | 2018-11-09 | 衢州顺安电子商务有限公司 | 一种环保用酶制剂制备装置 |
| EP3721871A1 (de) | 2019-04-11 | 2020-10-14 | ADD Advanced Drug Delivery Technologies, Ltd. | Verfahren zur kontinuierlichen herstellung eines wirkstoffgranulats |
| EP3721870A1 (de) | 2019-04-11 | 2020-10-14 | ADD Advanced Drug Delivery Technologies, Ltd. | Verfahren zur kontinuierlichen herstellung eines wirkstoffgranulats |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1495427A (fr) | 1966-03-02 | 1967-09-22 | Progil | Procédé et appareil de granulation de produits fluides |
| US3777874A (en) * | 1971-12-22 | 1973-12-11 | Air Prod & Chem | Powder deposition system |
| GB1435905A (en) * | 1972-11-03 | 1976-05-19 | Unilever Ltd | Enzyme granules |
| SE394604B (sv) * | 1974-12-18 | 1977-07-04 | Uddeholms Ab | Forfarande och anordning for pulvertillverkning genom granulering av en smelta |
| DD119304A1 (pt) | 1975-04-23 | 1976-04-12 | ||
| US4100263A (en) * | 1976-12-08 | 1978-07-11 | Ciba-Geigy Corporation | Process for preparing cyanogen chloride and gaseous chlorine |
| IN155886B (pt) * | 1980-05-07 | 1985-03-23 | Toyo Engineering Corp | |
| JPS56155630A (en) * | 1980-05-07 | 1981-12-01 | Mitsui Toatsu Chem Inc | Granulator utilizing jet layer |
| US5213820A (en) | 1984-02-27 | 1993-05-25 | Bayer Aktiengesellschaft | Process and device for fluidized bed spray granulation |
| DE3808277A1 (de) | 1988-03-12 | 1989-09-21 | Bayer Ag | Verfahren und vorrichtung zur wirbelschichtspruehgranulation |
| EP0163836B1 (de) * | 1984-04-07 | 1988-10-12 | Bayer Ag | Verfahren und Vorrichtung zur Herstellung von Granulaten |
| DE3530744A1 (de) | 1985-08-28 | 1987-03-05 | Herbert Huettlin | Fliessbettapparatur |
| DE3609133A1 (de) * | 1986-03-19 | 1987-09-24 | Glatt Gmbh | Vorrichtung zum pelletieren od. dgl. behandeln von teilchen sowie damit durchfuehrbares verfahren |
| DK435587D0 (da) * | 1987-08-21 | 1987-08-21 | Novo Industri As | Fremgangsmaade til fremstilling af et enzymholdigt granulat |
| US4968443A (en) * | 1988-07-22 | 1990-11-06 | Colgate-Palmolive Company | Antistatic laundry detergent composition and processes therefor |
| US5575086A (en) * | 1994-09-16 | 1996-11-19 | Combustion Engineering, Inc. | Fluidized bed with improved nozzle construction |
| AU741828B2 (en) * | 1997-06-04 | 2001-12-13 | Basf Aktiengesellschaft | High-activity phytase compositions |
| TW409035B (en) | 1997-06-04 | 2000-10-21 | Gist Brocades Bv | Starch-based enzyme granulates |
| DE19922753A1 (de) * | 1999-05-18 | 2000-11-23 | Basf Ag | Enzym-Instantformulierungen für die Tierernährung |
| US6579365B1 (en) * | 1999-11-22 | 2003-06-17 | Glatt Air Techniques, Inc. | Apparatus for coating tablets |
| DE50011442D1 (de) | 2000-02-18 | 2005-12-01 | Glatt Ingtech Gmbh | Verfahren zur Herstellung von Vollwaschmitteln und Vollwaschmittelkomponenten |
| MXPA02010757A (es) | 2000-05-04 | 2004-05-17 | Dsm Nv | Proceso en lecho fluidizado para la produccion de granulos de enzimas. |
| DE10146778B4 (de) | 2001-09-22 | 2009-02-05 | Glatt Ingenieurtechnik Gmbh | Verfahren und Wirbelschichtanlage zur Herstellung von kompakten Feststoffpartikeln |
| EP1467629B1 (en) * | 2002-01-15 | 2009-07-15 | Basf Se | Granulates containing feed-enzymes |
-
2004
- 2004-05-26 PL PL04739366T patent/PL1638678T3/pl unknown
- 2004-05-26 CA CA2528637A patent/CA2528637C/en not_active Expired - Fee Related
- 2004-05-26 AT AT04739366T patent/ATE526077T1/de active
- 2004-05-26 JP JP2006515795A patent/JP4589312B2/ja not_active Expired - Fee Related
- 2004-05-26 DK DK04739366.5T patent/DK1638678T3/da active
- 2004-05-26 ES ES04739366T patent/ES2374191T3/es not_active Expired - Lifetime
- 2004-05-26 US US10/560,372 patent/US8231938B2/en not_active Expired - Fee Related
- 2004-05-26 EP EP04739366A patent/EP1638678B1/de not_active Expired - Lifetime
- 2004-05-26 AU AU2004245660A patent/AU2004245660B2/en not_active Ceased
- 2004-05-26 WO PCT/EP2004/005662 patent/WO2004108911A2/de not_active Ceased
- 2004-05-26 PT PT04739366T patent/PT1638678E/pt unknown
- 2004-05-26 MX MXPA05012879A patent/MXPA05012879A/es active IP Right Grant
- 2004-05-26 BR BRPI0410977-5A patent/BRPI0410977A/pt not_active Application Discontinuation
- 2004-06-07 US US10/862,238 patent/US7691438B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1638678A2 (de) | 2006-03-29 |
| MXPA05012879A (es) | 2006-06-23 |
| JP4589312B2 (ja) | 2010-12-01 |
| PT1638678E (pt) | 2012-01-05 |
| US7691438B2 (en) | 2010-04-06 |
| ES2374191T3 (es) | 2012-02-14 |
| US20070093403A1 (en) | 2007-04-26 |
| CA2528637C (en) | 2012-10-23 |
| US20060088923A1 (en) | 2006-04-27 |
| EP1638678B1 (de) | 2011-09-28 |
| JP2007523616A (ja) | 2007-08-23 |
| US8231938B2 (en) | 2012-07-31 |
| CA2528637A1 (en) | 2004-12-16 |
| ATE526077T1 (de) | 2011-10-15 |
| DK1638678T3 (da) | 2012-01-09 |
| HK1095110A1 (en) | 2007-04-27 |
| PL1638678T3 (pl) | 2012-02-29 |
| AU2004245660A1 (en) | 2004-12-16 |
| AU2004245660B2 (en) | 2009-06-11 |
| WO2004108911A2 (de) | 2004-12-16 |
| WO2004108911A3 (de) | 2005-02-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 11, 13 E 25 DA LPI |
|
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |
|
| B15K | Others concerning applications: alteration of classification |
Ipc: C12N 9/98 (2006.01), A23K 20/189 (2016.01), A23K 4 |