BRPI0411079A - composições farmacêuticas compreendendo atorvastatina, fabricadas sem granulação - Google Patents

composições farmacêuticas compreendendo atorvastatina, fabricadas sem granulação

Info

Publication number
BRPI0411079A
BRPI0411079A BRPI0411079-0A BRPI0411079A BRPI0411079A BR PI0411079 A BRPI0411079 A BR PI0411079A BR PI0411079 A BRPI0411079 A BR PI0411079A BR PI0411079 A BRPI0411079 A BR PI0411079A
Authority
BR
Brazil
Prior art keywords
unit dosage
dosage form
atorvastatin
granulation
per
Prior art date
Application number
BRPI0411079-0A
Other languages
English (en)
Inventor
Alfred Berchielli
Kenneth Craig Waterman
Patrick David Daugherity
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33551781&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0411079(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of BRPI0411079A publication Critical patent/BRPI0411079A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

"COMPOSIçõES FARMACêUTICAS COMPREENDENDO ATORVASTATINA, FABRICADAS SEM GRANULAçãO". Uma forma de dosagem unitária compreendendo atorvastatina, ou um seu sal farmaceuticamente aceitável, preparada sem uma etapa de granulação, onde a potência de atorvastatina medida, da referida forma de dosagem, apresenta um desvio padrão relativo (DPR), para a potência de atorvastatina, por forma de dosagem unitária, não superior a cerca de 7,8%, quando a referida forma de dosagem unitária é preparada a uma velocidade superior a 10.000 formas de dosagem unitárias, por hora, por cada forma de dosagem unitária, por máquina, bem como, a forma de dosagem unitária, em combinação com, pelo menos, um fármaco ativo, métodos para preparação de formas de dosagem unitárias, kits para conterem composições deste tipo e, a utilização das referidas composições, para o fabrico de um medicamento para o tratamento da hipercolesterolemia e/ou da hiperlipidemia, da osteoporose, da hiperplasia prostática benigna (HPB) e, da Doença de Alzheimer, utilizando uma quantidade terapeuticamente eficaz das formas de dosagem unitárias.
BRPI0411079-0A 2003-06-12 2004-06-01 composições farmacêuticas compreendendo atorvastatina, fabricadas sem granulação BRPI0411079A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47791803P 2003-06-12 2003-06-12
PCT/IB2004/001845 WO2004110409A1 (en) 2003-06-12 2004-06-01 Pharmaceutical compositions comprising atorvastatin manufactured without granulation

Publications (1)

Publication Number Publication Date
BRPI0411079A true BRPI0411079A (pt) 2006-07-25

Family

ID=33551781

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0411079-0A BRPI0411079A (pt) 2003-06-12 2004-06-01 composições farmacêuticas compreendendo atorvastatina, fabricadas sem granulação

Country Status (23)

Country Link
US (2) US20050271717A1 (pt)
EP (2) EP1977738A1 (pt)
JP (1) JP2006527256A (pt)
KR (1) KR20060028768A (pt)
CN (1) CN100446757C (pt)
AR (1) AR044775A1 (pt)
AT (1) ATE399537T1 (pt)
AU (1) AU2004246866A1 (pt)
BR (1) BRPI0411079A (pt)
CA (1) CA2465621A1 (pt)
CO (1) CO5640072A2 (pt)
DE (1) DE602004014765D1 (pt)
DK (1) DK1635791T3 (pt)
ES (1) ES2305775T3 (pt)
MX (1) MXPA05013392A (pt)
NO (1) NO20055185L (pt)
PL (1) PL1635791T3 (pt)
PT (1) PT1635791E (pt)
RU (1) RU2314804C2 (pt)
SI (1) SI1635791T1 (pt)
TW (1) TW200509905A (pt)
WO (1) WO2004110409A1 (pt)
ZA (1) ZA200509906B (pt)

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PT1635791E (pt) 2008-09-10
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PL1635791T3 (pl) 2008-11-28
CO5640072A2 (es) 2006-05-31
JP2006527256A (ja) 2006-11-30
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US20090226510A1 (en) 2009-09-10
EP1635791B1 (en) 2008-07-02
SI1635791T1 (sl) 2008-10-31
ES2305775T3 (es) 2008-11-01
ZA200509906B (en) 2007-01-31
WO2004110409A1 (en) 2004-12-23
CA2465621A1 (en) 2004-12-12
EP1635791A1 (en) 2006-03-22
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AR044775A1 (es) 2005-10-05
MXPA05013392A (es) 2006-03-09
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AU2004246866A1 (en) 2004-12-23
KR20060028768A (ko) 2006-04-03
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