BRPI0412670A - uso de polimorfismo de nucleotìdeo simples na região de codificação de gene receptor de leptina de suìno para melhorar a produção da carne de porco - Google Patents
uso de polimorfismo de nucleotìdeo simples na região de codificação de gene receptor de leptina de suìno para melhorar a produção da carne de porcoInfo
- Publication number
- BRPI0412670A BRPI0412670A BRPI0412670-0A BRPI0412670A BRPI0412670A BR PI0412670 A BRPI0412670 A BR PI0412670A BR PI0412670 A BRPI0412670 A BR PI0412670A BR PI0412670 A BRPI0412670 A BR PI0412670A
- Authority
- BR
- Brazil
- Prior art keywords
- suine
- gene
- coding region
- plepr
- nucleotide polymorphism
- Prior art date
Links
- 235000015277 pork Nutrition 0.000 title abstract 3
- 108091026890 Coding region Proteins 0.000 title abstract 2
- 239000002773 nucleotide Substances 0.000 title abstract 2
- 108010019813 leptin receptors Proteins 0.000 title 1
- 125000003729 nucleotide group Chemical group 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
- 108010092277 Leptin Proteins 0.000 abstract 1
- 102000016267 Leptin Human genes 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 241000282898 Sus scrofa Species 0.000 abstract 1
- 101001129924 Sus scrofa Leptin receptor Proteins 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004473 Threonine Substances 0.000 abstract 1
- 238000009395 breeding Methods 0.000 abstract 1
- 230000001488 breeding effect Effects 0.000 abstract 1
- 210000000349 chromosome Anatomy 0.000 abstract 1
- 235000021316 daily nutritional intake Nutrition 0.000 abstract 1
- 244000144980 herd Species 0.000 abstract 1
- NRYBAZVQPHGZNS-ZSOCWYAHSA-N leptin Chemical compound O=C([C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(C)C)CCSC)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CS)C(O)=O NRYBAZVQPHGZNS-ZSOCWYAHSA-N 0.000 abstract 1
- 229940039781 leptin Drugs 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
- 229930182817 methionine Natural products 0.000 abstract 1
- 102000054765 polymorphisms of proteins Human genes 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/124—Animal traits, i.e. production traits, including athletic performance or the like
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
"USO DE POLIMORFISMO DE NUCLEOTìDEO SIMPLES NA REGIãO DE CODIFICAçãO DO GENE RECEPTOR DE LEPTINA DE SUìNO PARA MELHORAR A PRODUçãO DA CARNE DE PORCO". A presente invenção refere-se à identificação e ao uso de informação relacionada a um ou mais polimorfismos do gene receptor de leptina de porco (pLEPR) como um marcador na identificação de animais que se prestam como rebanho reprodutor para produção melhorada da carne de porco. Um polimorfismo particular do gene pLEPR resulta em um resíduo de aminoácido metionina ou treonina na posição 69 da proteína que o gene pLEPR codifica. O gene pLEPR está localizado no cromossomo 6 de suíno e demonstrou estar associado com a determinação de ingestão diária de alimento, dentre outros fatores.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49315803P | 2003-08-07 | 2003-08-07 | |
| US55358204P | 2004-03-16 | 2004-03-16 | |
| PCT/US2004/023050 WO2005017204A2 (en) | 2003-08-07 | 2004-07-16 | Use single nucleotide polymorphsm in the coding region of the porcine leptin receptor gene to enhance pork production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0412670A true BRPI0412670A (pt) | 2006-10-03 |
Family
ID=34197970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0412670-0A BRPI0412670A (pt) | 2003-08-07 | 2004-07-16 | uso de polimorfismo de nucleotìdeo simples na região de codificação de gene receptor de leptina de suìno para melhorar a produção da carne de porco |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20070190527A1 (pt) |
| EP (1) | EP1651777B1 (pt) |
| AR (1) | AR045345A1 (pt) |
| AT (1) | ATE401425T1 (pt) |
| AU (1) | AU2004265629A1 (pt) |
| BR (1) | BRPI0412670A (pt) |
| CA (1) | CA2533500A1 (pt) |
| DE (1) | DE602004015113D1 (pt) |
| MX (1) | MXPA06001487A (pt) |
| WO (1) | WO2005017204A2 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100291267A1 (en) | 2007-11-29 | 2010-11-18 | Monsanto Technology Llc | Meat products with increased levels of beneficial fatty acids |
| CN102286466A (zh) * | 2011-07-14 | 2011-12-21 | 南京农业大学 | cDNA-AFLP法分离苏太猪肌内脂肪含量差异表达基因的方法 |
| CN103937787B (zh) * | 2014-04-08 | 2017-01-04 | 广西大学 | 一种与小型猪2型糖尿病有关的snp标记、其检测方法和用途 |
| CN104342435B (zh) * | 2014-07-23 | 2017-10-20 | 湖南农业大学 | 猪背膘厚相关slc13a5基因的分子克隆及应用 |
| CN107267631A (zh) * | 2017-07-18 | 2017-10-20 | 华南农业大学 | 一种影响猪日增重性状的snp标记及其应用 |
| CN107937558B (zh) * | 2017-11-14 | 2020-10-27 | 温氏食品集团股份有限公司 | 一个与猪平均日采食量相关的snp位点及其应用 |
| CN112481385B (zh) * | 2019-09-12 | 2022-07-08 | 中国农业科学院农业基因组研究所 | 一种用于检测猪背膘厚的snp标记及其应用 |
| CN113355427B (zh) * | 2020-03-04 | 2022-07-08 | 中国农业科学院农业基因组研究所 | 一种与猪背膘厚相关的snp标记及其利用方法 |
| CN113355430A (zh) * | 2020-03-06 | 2021-09-07 | 中国农业科学院农业基因组研究所 | 一种用于鉴定猪背膘厚度的snp标记及其应用方法 |
| CN116004857B (zh) * | 2023-02-23 | 2025-03-28 | 内蒙古大学 | 蒙古羊基因lepr的分子标记的特异性引物及其应用 |
| CN118910267B (zh) * | 2024-06-18 | 2025-12-12 | 湖北省农业科学院畜牧兽医研究所 | 猪prkn基因第三内含子中的分子标记、引物、试剂盒、方法及应用 |
| CN120843693B (zh) * | 2025-07-30 | 2026-01-30 | 中国农业科学院北京畜牧兽医研究所 | 与肥育猪生长性能、哺乳母猪繁殖性能及猪肉风味相关的分子标记的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6458531B1 (en) * | 1996-10-09 | 2002-10-01 | Iowa State University Research Foundation | Leptin receptor gene as a genetic marker for leanness in pigs |
| US20100124747A1 (en) * | 2008-11-03 | 2010-05-20 | University Of Southern California | Compositions and methods for diagnosis or prognosis of testicular cancer |
-
2004
- 2004-07-16 AT AT04778518T patent/ATE401425T1/de not_active IP Right Cessation
- 2004-07-16 DE DE602004015113T patent/DE602004015113D1/de not_active Expired - Fee Related
- 2004-07-16 MX MXPA06001487A patent/MXPA06001487A/es active IP Right Grant
- 2004-07-16 WO PCT/US2004/023050 patent/WO2005017204A2/en not_active Ceased
- 2004-07-16 US US10/566,941 patent/US20070190527A1/en not_active Abandoned
- 2004-07-16 CA CA002533500A patent/CA2533500A1/en not_active Abandoned
- 2004-07-16 BR BRPI0412670-0A patent/BRPI0412670A/pt not_active IP Right Cessation
- 2004-07-16 AU AU2004265629A patent/AU2004265629A1/en not_active Abandoned
- 2004-07-16 EP EP04778518A patent/EP1651777B1/en not_active Revoked
- 2004-08-06 AR ARP040102818A patent/AR045345A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1651777B1 (en) | 2008-07-16 |
| WO2005017204A2 (en) | 2005-02-24 |
| US20070190527A1 (en) | 2007-08-16 |
| EP1651777A2 (en) | 2006-05-03 |
| ATE401425T1 (de) | 2008-08-15 |
| CA2533500A1 (en) | 2005-02-24 |
| WO2005017204B1 (en) | 2005-09-29 |
| AU2004265629A1 (en) | 2005-02-24 |
| WO2005017204A3 (en) | 2005-07-21 |
| AR045345A1 (es) | 2005-10-26 |
| MXPA06001487A (es) | 2006-05-15 |
| DE602004015113D1 (de) | 2008-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A E 7A ANUIDADE(S). |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2112 DE 28/06/2011. |