BRPI0412905A - composição farmacêutica como forma de dosagem sólida e método de fabricação - Google Patents
composição farmacêutica como forma de dosagem sólida e método de fabricaçãoInfo
- Publication number
- BRPI0412905A BRPI0412905A BRPI0412905-9A BRPI0412905A BRPI0412905A BR PI0412905 A BRPI0412905 A BR PI0412905A BR PI0412905 A BRPI0412905 A BR PI0412905A BR PI0412905 A BRPI0412905 A BR PI0412905A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical composition
- dosage form
- solid dosage
- manufacturing
- desmopressin
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 5
- 239000007909 solid dosage form Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 108010000437 Deamino Arginine Vasopressin Proteins 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- NFLWUMRGJYTJIN-NXBWRCJVSA-N desmopressin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSCCC(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O)=O)CCC(=O)N)C1=CC=CC=C1 NFLWUMRGJYTJIN-NXBWRCJVSA-N 0.000 abstract 2
- 229960004281 desmopressin Drugs 0.000 abstract 2
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"COMPOSIçãO FARMACêUTICA COMO FORMA DE DOSAGEM SóLIDA E MéTODO DE FABRICAçãO". A presente invenção refere-se a uma nova composição farmacêutica como forma de dosagem sólida compreendendo desmopressina como ingrediente terapeuticamente ativo, e a um método para fabricar o mesmo. A invenção refere-se a uma composição farmacêutica como forma de dosagem sólida compreendendo desmopressina, ou um sal farmaceuticamente aceitável da mesma, como um ingrediente terapeuticamente ativo junto com um excipiente, diluente ou veículo farmaceuticamente aceitável, ou mistura dos mesmos, em que a composição farmacêutica é composta de um granulado compreendendo e contém lubrificante em uma quantidade de 0,05 a menos que 0,5 por cento em peso da dita composição farmacêutica.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/626,857 US7022340B2 (en) | 2003-07-25 | 2003-07-25 | Pharmaceutical composition as solid dosage form and method for manufacturing thereof |
| EP03016945A EP1500390B1 (en) | 2003-07-25 | 2003-07-25 | Pharmaceutical desmopressin composition as solid dosage form and method for manufacturing thereof |
| PCT/EP2004/051538 WO2005011640A2 (en) | 2003-07-25 | 2004-07-19 | Pharmaceutical desmopressin composition as solid dosage form and method for manufacturing thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0412905A true BRPI0412905A (pt) | 2006-09-26 |
Family
ID=34117527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0412905-9A BRPI0412905A (pt) | 2003-07-25 | 2004-07-19 | composição farmacêutica como forma de dosagem sólida e método de fabricação |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7022340B2 (pt) |
| EP (1) | EP1500390B1 (pt) |
| JP (1) | JP4430673B2 (pt) |
| KR (1) | KR20050104331A (pt) |
| AT (1) | ATE301990T1 (pt) |
| AU (1) | AU2004260625B2 (pt) |
| BR (1) | BRPI0412905A (pt) |
| CA (1) | CA2490335C (pt) |
| DE (1) | DE60301351T2 (pt) |
| DK (1) | DK1500390T3 (pt) |
| ES (1) | ES2243840T3 (pt) |
| IL (1) | IL187591A0 (pt) |
| MX (1) | MXPA06000903A (pt) |
| NO (1) | NO327328B1 (pt) |
| NZ (1) | NZ544104A (pt) |
| PL (1) | PL379704A1 (pt) |
| PT (1) | PT1500390E (pt) |
| RU (1) | RU2303439C2 (pt) |
| SI (1) | SI1500390T1 (pt) |
| TW (1) | TWI268782B (pt) |
| WO (1) | WO2005011640A2 (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0210397D0 (en) * | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
| US7094545B2 (en) * | 2003-04-30 | 2006-08-22 | Ferring Bv | Pharmaceutical composition as solid dosage form and method for manufacturing thereof |
| CN1826099B (zh) * | 2003-07-25 | 2010-06-09 | 凡林有限公司 | 固体剂型药物组合物及其制造方法 |
| PT1530967E (pt) * | 2003-11-13 | 2006-09-29 | Ferring Bv | Embalagem blister e uma forma de dosagem solida que compreende desmopressina. |
| CA2490601C (en) * | 2003-12-29 | 2006-05-02 | Ferring B.V. | Method for preparing solid dosage form of desmopressin |
| US7018653B2 (en) * | 2003-12-29 | 2006-03-28 | Ferring B.V. | Method for preparing solid dosage form of desmopressin |
| SE0600482L (sv) * | 2006-03-02 | 2006-11-14 | Ferring Int Ct Sa | Farmaceutisk sammansättning innefattande desmopressin, kiseldioxid och stärkelse |
| WO2009021007A1 (en) | 2007-08-06 | 2009-02-12 | Serenity Pharmaceuticals Corporation | Methods and devices for desmopressin drug delivery |
| ES2319054B1 (es) | 2007-08-06 | 2010-02-12 | Gp Pharm S.A. | Composicion farmaceutica oral de desmopresina. |
| WO2009114226A1 (en) * | 2008-03-11 | 2009-09-17 | Mallinckrodt Inc. | Use of magnesium stearate dihydrate for lubrication of solid pharmaceutical compositions |
| US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
| US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
| NO3085381T3 (pt) * | 2008-05-21 | 2018-09-15 | ||
| EP2345689B1 (en) * | 2008-09-30 | 2017-04-12 | Mitsui Chemicals, Inc. | Fiber-reinforced resin composition and molded object thereof |
| JP2022130075A (ja) * | 2021-02-25 | 2022-09-06 | フロイント産業株式会社 | 顆粒及びその製造方法、並びに錠剤 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8306367L (sv) * | 1983-11-18 | 1985-05-19 | Ferring Ab | Antidiuretiskt verkande farmaceutiskt preparat |
| US4675188A (en) * | 1985-08-02 | 1987-06-23 | Stauffer Chemical Company | Granular anhydrous dicalcium phosphate compositions suitable for direct compression tableting |
| US4820627A (en) * | 1986-03-24 | 1989-04-11 | Em Diagnostic Systems, Inc. | Method of preparing particles suitable for tabletting into diagnostic reagents |
| UA37214C2 (uk) * | 1991-01-30 | 2001-05-15 | Дзе Веллкам Фаундейшн Лімітед | Таблетки, що диспергуються у воді, та спосіб їх виготовлення |
| US5482931A (en) | 1993-06-29 | 1996-01-09 | Ferring Ab | Stabilized pharmaceutical peptide compositions |
| WO1995018602A1 (en) | 1994-01-11 | 1995-07-13 | Alkermes Controlled Therapeutics, Inc. | ORAL DOSAGE FORM OF DESMOPRESSIN (dDAVP) |
| SE9400918L (sv) * | 1994-03-18 | 1995-09-19 | Anne Fjellstad Paulsen | Stabiliserad komposition för oral administrering av peptider |
| US5849322A (en) | 1995-10-23 | 1998-12-15 | Theratech, Inc. | Compositions and methods for buccal delivery of pharmaceutical agents |
| GB9526495D0 (en) | 1995-12-23 | 1996-02-28 | Knoll Ag | Therapeutic agents |
| DE19602757A1 (de) * | 1996-01-26 | 1997-07-31 | Boehringer Mannheim Gmbh | Feste Instant-Release-Darreichungsformen und Verfahren zu ihrer Herstellung |
| SE9604341D0 (sv) * | 1996-11-26 | 1996-11-26 | Ferring Bv | Hepta-peptide oxytocin analogue |
| WO2000009423A1 (es) | 1998-08-11 | 2000-02-24 | Jaime Marti Sala | Silo para almacenamiento de cuerpos huecos ligeros |
| AT409081B (de) | 2000-02-16 | 2002-05-27 | Gebro Pharma Gmbh | Stabile, nasal, oral oder sublingual anwendbare pharmazeutische zubereitung |
| GB0009469D0 (en) * | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formalities for use in inhaler devices |
| JP2004500424A (ja) | 2000-04-17 | 2004-01-08 | ヴェクトゥラ リミテッド | 吸入器で使用するための製剤 |
| PE20011227A1 (es) * | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
| GB0010709D0 (en) | 2000-05-03 | 2000-06-28 | Vectura Ltd | Powders for use a in dry powder inhaler |
| ES2292598T3 (es) | 2000-06-27 | 2008-03-16 | Vectura Limited | Metodo para producir particulas para usar en una composicion farmaceutica. |
| KR100642976B1 (ko) * | 2001-05-10 | 2006-11-10 | 아스텔라스세이야쿠 가부시키가이샤 | 구강내 신속 붕괴성 정제 및 이의 제조방법 |
| CA2460132A1 (en) | 2001-10-15 | 2003-04-24 | Roehm Gmbh & Co. Kg | Use of a copolymer to produce a galenic form containing a peptide or a protein as active agent |
| DE60307082D1 (de) | 2002-05-07 | 2006-09-07 | Ferring Bv | In der mundhöhle dispergierbare phamarzeutische zusammensetzung mit desmopressin |
| ATE291419T1 (de) * | 2003-04-30 | 2005-04-15 | Ferring Bv | Feste dosierungsform mit desmopressin |
| US7094545B2 (en) * | 2003-04-30 | 2006-08-22 | Ferring Bv | Pharmaceutical composition as solid dosage form and method for manufacturing thereof |
-
2003
- 2003-07-25 AT AT03016945T patent/ATE301990T1/de active
- 2003-07-25 EP EP03016945A patent/EP1500390B1/en not_active Revoked
- 2003-07-25 PT PT03016945T patent/PT1500390E/pt unknown
- 2003-07-25 US US10/626,857 patent/US7022340B2/en not_active Expired - Fee Related
- 2003-07-25 ES ES03016945T patent/ES2243840T3/es not_active Expired - Lifetime
- 2003-07-25 DE DE60301351T patent/DE60301351T2/de not_active Expired - Lifetime
- 2003-07-25 SI SI200330100T patent/SI1500390T1/sl unknown
- 2003-07-25 DK DK03016945T patent/DK1500390T3/da active
-
2004
- 2004-07-19 KR KR1020057006309A patent/KR20050104331A/ko not_active Ceased
- 2004-07-19 JP JP2006520833A patent/JP4430673B2/ja not_active Expired - Fee Related
- 2004-07-19 AU AU2004260625A patent/AU2004260625B2/en not_active Ceased
- 2004-07-19 PL PL379704A patent/PL379704A1/pl not_active Application Discontinuation
- 2004-07-19 CA CA002490335A patent/CA2490335C/en not_active Expired - Fee Related
- 2004-07-19 WO PCT/EP2004/051538 patent/WO2005011640A2/en not_active Ceased
- 2004-07-19 NZ NZ544104A patent/NZ544104A/en not_active IP Right Cessation
- 2004-07-19 RU RU2005141230/15A patent/RU2303439C2/ru not_active IP Right Cessation
- 2004-07-19 MX MXPA06000903A patent/MXPA06000903A/es active IP Right Grant
- 2004-07-19 BR BRPI0412905-9A patent/BRPI0412905A/pt not_active Application Discontinuation
- 2004-07-23 TW TW093122090A patent/TWI268782B/zh not_active IP Right Cessation
-
2005
- 2005-04-19 NO NO20051896A patent/NO327328B1/no not_active IP Right Cessation
-
2007
- 2007-11-22 IL IL187591A patent/IL187591A0/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005011640A2 (en) | 2005-02-10 |
| RU2005141230A (ru) | 2006-07-10 |
| US7022340B2 (en) | 2006-04-04 |
| JP4430673B2 (ja) | 2010-03-10 |
| ATE301990T1 (de) | 2005-09-15 |
| AU2004260625A1 (en) | 2005-02-10 |
| EP1500390A1 (en) | 2005-01-26 |
| PT1500390E (pt) | 2005-10-31 |
| EP1500390B1 (en) | 2005-08-17 |
| HK1072009A1 (en) | 2005-08-12 |
| MXPA06000903A (es) | 2006-05-04 |
| DK1500390T3 (da) | 2005-09-19 |
| DE60301351D1 (de) | 2005-09-22 |
| NZ544104A (en) | 2008-06-30 |
| KR20050104331A (ko) | 2005-11-02 |
| US20050019392A1 (en) | 2005-01-27 |
| PL379704A1 (pl) | 2006-11-13 |
| TW200509995A (en) | 2005-03-16 |
| NO327328B1 (no) | 2009-06-08 |
| SI1500390T1 (sl) | 2006-02-28 |
| ES2243840T3 (es) | 2005-12-01 |
| WO2005011640A3 (en) | 2005-03-24 |
| AU2004260625B2 (en) | 2007-12-06 |
| RU2303439C2 (ru) | 2007-07-27 |
| JP2007517762A (ja) | 2007-07-05 |
| IL187591A0 (en) | 2008-03-20 |
| NO20051896L (no) | 2005-04-19 |
| TWI268782B (en) | 2006-12-21 |
| CA2490335C (en) | 2006-01-31 |
| DE60301351T2 (de) | 2006-01-19 |
| CA2490335A1 (en) | 2005-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |